3 Houston innovators to know with exciting new announcements

Who's who

New funds, new classes, and new opportunities for mentorship — these are this week's Houston innovators to know. Courtesy photos

While last week's innovators to know were all starting new jobs, these three for this week are starting new endeavors — from multi-million-dollar funds to education programs. Here are this week's three innovators to know.

Barbara Burger, president of Chevron Technology Ventures

Courtesy of CTV

Houston-based Chevron Technology Ventures announced a new $90 million fund to focus scalable tech companies that could improve and advance Chevron's oil and gas business.

Leading Fund VII is CTV president, Barbara Burger. According to the release, the fund will target early- to mid-stage companies and limited partnership funds.

"CTV serves as an excellent source within Chevron for new business models and novel technologies that can deliver value to the enterprise through their integration," Burger says in the release. "We are using venture capital as a conduit for early access to innovation and to build a pipeline of innovation for Chevron." Read the full story here.

Anthony Ambler, dean of the College of Technology at the University of Houston

Courtesy of UH

Undergraduate students at the University of Houston now have the option to major or minor in Technology Leadership and Innovation Management or minor in Applied Innovation, thanks, in part, to the College of Technology dean Anthony P. Ambler. All three options begin in the fall semester of this year, and the college is also interested in adding a master's and a PhD. program in Innovation Management or a post-graduate certificate program.

"We are about giving people the right tools to innovate," says Ambler in a release. "How do you get more people to the position where they are able to innovate?" Read the full story here.

Myrtle Jones, senior vice president at Halliburton

Courtesy of Myrtle Jones

Despite climbing through the ranks within the energy industry, Myrtle Jones says mentorship wasn't a big priority when she was in the early part of her career.

"I started working in the energy business in the early '80s, and women were new to the industry," Jones says. "We were somewhat getting ourselves established in the business world – there was no such thing as someone saying, 'We're going to get you linked up with mentors,' so you had to find role models."

Now, Jones has teamed up with Austin-based tech company, Bumble Bizz, that helps connect industry professionals and foster networking and mentoring opportunities. As of 2019, users have the option to see only women on the app, too, in order to foster their professional network of women. Read the full story here.

When Myrtle Jones was rising through the ranks of an energy company, she didn't have a female mentor to look up to. Now, she hopes help connect young women with mentors digitally. Courtesy of Myrtle Jones

This Houston energy executive is helping to create more women mentors in business

Featured Innovator

If you're a young woman in business, you're probably familiar with the struggle of finding a woman in business to be mentor. Here's some good news for those women: There's an app that's looking to change that, and there's a good chance you've already downloaded it on your phone.

In 2017, Austin-based Bumble, the dating and social mobile application, launched Bumble Bizz, an application that seeks to connect industry professionals and foster networking and mentoring opportunities. As of 2019, users have the option to see only women on the app, too, in order to foster their professional network of women.

Myrtle Jones, senior vice president at Houston-based Halliburton, knows a thing or two about the importance of mentorship, in large part because she went without it for much of her career. Jones, who's participating in Bumble Bizz's launch efforts, has become known as one of Houston's most influential and inspiring women in business. She spoke with InnovationMap about the importance of mentorship, how she wound up in the energy industry, and how interested professionals can become mentors to the next generation of professionals.

InnovationMap: What role did mentorship play in your career?

Myrtle Jones: I think people fail to realize that I came up in the industry before mentorship was really a thing. I started working in the energy business in the early '80s, and women were new to the industry. We were somewhat getting ourselves established in the business world – there was no such thing as someone saying, "We're going to get you linked up with mentors," so you had to find role models. I always had role models, and I always looked at the fact that women should have an equal opportunity in the workforce, and that we belonged in the workforce.

I was going to make my way in corporate America, and my motivation was believing that we had just as much right to be out here as men did.

IM: Did you have a mentor in your earlier days in the professional world?

MJ: A very wonderful sponsor came in as a treasurer when I was at GlobalSantaFe [now Transocean], and he was eventually promoted to CFO. He was someone who picked me out of the crowd and noticed I brought a lot of value. He brought me to executive meetings and board meeting and gave me an opportunity to show what I could do.

IM: How'd you get involved in the energy industry?

MJ: It wasn't that I was looking to go into energy. At the time I got out of school, the hottest job market was Houston, Texas, and it was the energy business. I went to Mississippi State, and the oil and gas companies were expanding their search outside of Texas and attracting people to move to Texas. So, that's how I ended up in the business. Other than the energy business, the economy was a bit slow around the rest of the country.

IM: What are some of the professional obstacles and adversities that you've faced as a female, especially in a stereotypically male-dominated industry?

MJ: First off, it was men getting used to seeing women in this industry, and just having to build those relationships and build mutual trust. A lot of it was just building trust, and overcoming a lot of prior stereotypes and beliefs that people had about the role [of women] in the workplace.

IM: Tell me about the role of technology and innovation at Halliburton.

MJ: There's so much technology development at Halliburton. A lot of people don't realize that Halliburton is a technology company. We have a fully fledged research and development center and we file hundreds of patents each year. The technology that Halliburton has developed has led to significant improvements in terms of oilfield services.

IM: What's your advice for folks reading this who are interested in mentoring, but aren't sure how to get started?

MJ: Make yourself open to it. When I'm in networking situations, and I'm meeting someone who's committed to their career, and they're looking for ways to talk to me, I open myself to that opportunity. I have a number of people who I mentor at Halliburton. For people who want to be mentors, it's really not that hard. [Mentees] are looking for that sounding board, and for someone who's "been there, done that."

So, even without having a formal organization to go through, people can become a mentor through their own network, or seek out organizations that have formal mentoring programs.

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Portions of this interview have been edited.

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Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

     
  • $1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
  • $922 million for the University of Houston System
  • $167 million for Texas Southern University
  • $10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

     
  • Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
  • Created the Lake Houston Dredging and Maintenance District
  • Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

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