Long-time innovator reflects on Houston ecosystem development, shares why he's bullish on human performance

houston innovators podcast episode 251

Jon Nordby's career has been focused on cultivating a culture for innovation, and now he's focused on human potential technology opportunities. Photo courtesy

In his role overseeing startup accelerators for MassChallenge, Jon Nordby started noticing one industry vertical stood out in terms of success and opportunities: Human potential. Now, Nordby is a founding member of an investment firm looking for those opportunities.

Nordby, who served in various leadership roles at MassChallenge — including managing director and head of ecosystems — said he started realizing the opportunities within the organization's space and sports tech programs.

"What we realized over a couple of years running the program was that sports tech as a theme was too limiting," Nordby says on the Houston Innovators Podcast. "We were finding really great technologies, but we were limited at the market size of teams and leagues to deploy those technologies."

"Over the course of that program, we found that the things that were related more to human health and performance tended to out perform all of the other things related to sports tech — like media, entertainment, gambling," Nordby continues. "Still really great markets for those technologies, but we found a lot more traction for human performance."

Nordby joined the team at Anthropy Partners, which exists to support early stage technologies that are advancing human mental and physical performance, a little over a year ago.

Defining human performance, Nordby says he thinks about it in terms of the hardware and software of a human, or physical and cognitive abilities — and how both sides of the equation work together.

"Some of the early investments that we've made have been in three realms — sensing, data, and analytics," Nordby explains, sharing examples from the Anthropy portfolio companies.

While Nordby jokes that his interest in human performance might confuse people who know him to be not particularly athletic, his other current roles fall more in line with his career history. A three-time startup founder, Nordby worked for the Greater Houston Partnership at the time the organization launched Houston Exponential. He left GHP to lead strategy for HX before transitioning to MassChallenge. All throughout these roles, Nordby has a front row seat for witnessing what it takes to develop innovation ecosystems.

He co-founded the Anthropy's nonprofit efforts for developing innovation ecosystems, called Anthropy Constructive. This year, he founded EconWerks, a for-profit company that advises entities on creating sustainable innovation efforts.

Nordby says he's "seen where things go wrong when people with really great intentions but not a lot of exposure or pattern recognition to ecosystem development are making investments or decisions on how those ecosystems need to develop."

Usually, Nordby explains, it's an economic development or ill-informed investment decision. But wrong moves can devastate a potential startup hub.

"Typically, when an investment is made and it doesn't pan out the way they think it should, there's typically a five to eight-year cycle of no more investments being made," Nordby says on the show. "When you think about the long-term effect that has on an innovation economy — an eight-year gap where you're not investing in startups — that's a problem."

Nordby thinks back to the goal setting Houston did several years ago, and reflects on how the ecosystem locally has evolved over the years.

"The goal we always set internally was to create a culture of innovation and to have the spirit of innovation permeate through the city," Nordby says. "Between 2016 when we started that initiative and that work until now, that culture is wildly different. ... The ecosystem has come a very, very long way in terms of attracting and encouraging founders."

Samra Nawaz founded WellWorth to tackle the convoluted financial modeling process in upstream oil and gas. Photo courtesy of WellWorth

How this Houston SaaS startup plans to scale with future of energy in mind

houston innovators podcast episode 216

As much as she loves a good Excel spreadsheet, Samra Nawaz had just about had it with the convoluted — and not always completely accurate — process of building financial models within upstream oil and gas.

"Excel is generally a good tool to automate workflows and build really robust spreadsheets. I live in Excel — I have a spreadsheet for everything," Nawaz says on the Houston Innovators Podcast. "What Excel is not is a database."

Engineering teams work with massive amounts with data that's too big for Excel, she explains, so finance teams then have to work off of aggregated data to build their financial models. She was ranting about why there isn't a better process to her husband, Vinay Acharya, who suggested that they build it themselves.



After thinking it through together, the duo co-founded WellWorth in 2018. Since then, the company has developed its MVP, completed a few accelerators — Rice University's OwlSpark, MassChallenge, and Softeq Ventures, to name a few — and won this year's Startup Pitch Competition hosted by the Ion.

Now, the bootstrapped startup looks to 2024 to bring on its first venture capital investors and team members — first to thoroughly tackle upstream O&G before expanding into other parts of the energy sector, including renewables.

"We're focusing on a specific workflow, and that is for engineering and finance teams and automating the corporate financial modeling side of the workflow," Nawaz says. "But we also see a lot of the renewables companies sprouting up, and we understand the attention on renewables verticals is only going to increase in the next few years.

"We're building WellWorth in a very modular way, so that when the time is right, we can easily start working with customers in the renewable space as well," she adds.

Nawaz, CEO of WellWorth, shares more about her company's growth plan and the impact the technology has on its early customers on the podcast.

WellnessWits, founded by Kike Oduba to enhance patient-physician interaction, has integrated AI with the help of IBM. Photo via WellnessWits.com

Houston health tech startup taps into IBM tech for AI integration

teaming up

A Houston startup aimed at transforming healthcare with solutions for chronic disease and its prevention has teamed up with IBM technology.

WellnessWits has embedded IBM watsonx Assistant into its app for both iOS and Android. By making generative AI part of the app, WellnessWits now boasts an AI-based chat functionality.

That cutting-edge aspect of the platform allows patients to get information on chronic disease more quickly than ever, even before meeting with their physician. But it helps with that, too, aiding in scheduling appointments more easily with doctors who specialize in a host of chronic maladies.

“I founded WellnessWits as a platform for shared medical appointments where doctors with large patient loads can see them in groups and offer collective shared medical experiences to people suffering from chronic conditions. The goal is to bridge this divide, leveraging the strength of digital communities to enhance the overall well-being and healthcare experiences of individuals everywhere,” WellnessWits Founder and CEO Dr. Kike Oduba, a physician and informatician, writes in a blog post.

Oduba founded the company in 2018. In its early years, she participated in IBM’s First AI Cohort for Underrrepresented Founders Program. She believes that by using watsonx Assistant in her technology arsenal, WellnessWits will be a means to “digitize, standardize and automate care plans for patients dealing with chronic diseases.”

Diabetes management is a cornerstone of the company, but Oduba says that WellnessWits is similarly committed to impacting health issues including cancer, chronic pain, mental health, and obesity.

“By partnering with IBM, and academic leaders in institutions like The University of Texas, we aim to extend our reach and impact,” Oduba says.

In addition to the IBM program, Oduba and WellnessWits was selected for MassChallenge's recent cohort.

MassChallenge Startup Stories: WellnessWits Founder's Journey from Struggles to SuccessIn this inspiring 6-minute testimonial, we take you through the remarkable experience of Dr. Oduba, founder and CEO of ...

Houston founders — these four programs have applications open now. Photo via Getty Images

4 program deadlines Houston innovators should know about

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Editor's note: It's safe to say 2023 has fully kicked off as Houston's startup and innovation ecosystem has switched into second gear. A handful of programs — local and national — have opened applications for accelerators and pitch competitions. Scroll through to find one that applies to your company or a startup you know of. Take careful note of the deadlines since they'll be here before you know it.

Is something missing? Email natalie@innovationmap.com for editorial consideration.

Carbon to Value Initiative

Greentown Labs announced its looking for innovative companies with carbon-related technology. Photo via GreentownLabs.com

Greentown Labs announced that its Carbon to Value (C2V) Initiative has opened applications for its third set of startups.

"Supported by the New York State Energy Research and Development Authority, the C2V Initiative is a unique partnership among the Urban Future Lab at NYU Tandon School of Engineering, Greentown Labs, and Fraunhofer USA that’s driving the creation of a thriving innovation ecosystem for the commercialization of carbontech—technologies that capture and convert CO₂ into valuable end products or services," reads the news release. "Since the C2V Initiative's inception in 2020, the program has supported 18 groundbreaking carbontech startups—chosen from an exceptional pool of more than 230 applications."

The program is looking for companies with technologies within carbon capture, management, removal, or conversion and between TRL 4 and TRL 7. Selected companies will receive a $10,000 stipend and participate in the six-month program.

Applications are due by the end of the day on March 31. For more information and to apply, click here.

MassChallenge accelerators

MassChallenge has two accelerators open for applications. Photo courtesy of MassChallenge

MassChallenge has two programs with open applications:

MassChallenge US Early Stage Accelerator (Deadline: March 3)

This three-month program is industry agnostic and provides intensive support, guidance, tools, and connectivity to the greater MassChallenge community. Around 200 startups are selected per cohort that range in stage from those currently engaged in customer discovery work to validating a technology or service. For more information and to apply, click here.

MassChallenge HealthTech Accelerator (Deadline: February 6)

The 2023 HealthTech Sprint is an eight-week program intended to work intensely with 20 to 25 startups to accelerate the tools and technologies that could transform healthcare. The HealthTech Sprint program is designed to support mid-stage companies that possess a product/solution ready for scaling. For more information and to apply, click here.

Houston Energy Transition Initiative's Energy Ventures Pitch Competition 

HETI is bringing back its CERAWeek pitch competition. Image via houston.org

The Greater Houston Partnership's Houston Energy Transition Initiative, or HETI, is looking for participants for its Energy Ventures Pitch Competition at CERAWeek this year.

"This pitch competition brings together key members of the energy industry, investors, and startups to showcase the critical innovations and emerging technologies that create value from the world’s transition to low-carbon energy systems," reads the website.

HETI is looking for companies addressing challenges and opportunities in CCUS, hydrogen, energy storage, and the circular economy, are invited to present their well-developed business concepts to a world-class investor community.

Applications close February 9. For more information and to apply, click here.

Rice Business Plan Competition

The annual Rice Business Plan Competition has opened applications for student startups. Photo by Natalie Harms

Calling all student-founded startups — the largest and richest intercollegiate student startup competition, the Rice Business Plan Competition, has applications open. According to Rice, 784 RBPC alumni have raised $4.6 billion in funding and created over 5,500 jobs. This year's event is going to be held May 11 to 13.

The RBPC is open to all students from any university around the world. Teams must include at least one graduate-level student, and every team that is invited to compete in person at Rice University is guaranteed to take home at least one of the more that 60 expected cash prizes. For more information and to apply, click here.

MassChallenge has selected 10 Houston startups to participate in its 2022 United States cohort. Photo courtesy of MassChallenge

MassChallenge names 10 Houston companies to national cohort

class of 2022

Ten Houston companies have been chosen for MassChallenge’s 2022 United States cohort of early-stage startups.

The 10 Houston startups are:

  • BEMY Cosmetics, a maker of skin rejuvenation products based on RNA technology
  • Eisana Corp., whose products are designed to ease the side effects of breast cancer treatment
  • Enrichly, a self-esteem-based e-learning platform and gaming app
  • RE.STATEMENT, an online marketplace for upcycled clothing
  • Roxie Health, a virtual medical assigned geared toward preventing falls by seniors
  • Vivifi Medical, whose laparoscopic technology treats male infertility and prostate gland enlargement
  • Vouchpad, a provider of affordable student loans
  • Equiliberty, an equitable fintech platform focused on creating generational wealth
  • National Police Data, an organization creating an index of Police data in America
  • Cryodesalination, a new low cost desalination process focused on providing access to fresh water

In all, the MassChallenge innovation network selected 250 early-stage startups for this fall’s U.S. accelerator program in Houston, Austin, Dallas, Boston, and Providence, Rhode Island. Participants are eligible for equity-free cash prizes of as much as $1 million. MassChallenge is open to early-stage startups that have raised less than $1 million in equity funding and have generated less than $2 million in revenue over the past 12 months.

“We’re in the business of solving massive challenges, and to do that, we must continue to support diverse founders with bold ideas across geographies, industry verticals, and demographics in creative ways that allow them to wholly own their ideas and solve some of our world’s most pressing problems,” Hope Hopkins, head of acceleration at MassChallenge, says in a news release.

This year’s cohort will have access to MassChallenge’s new residency program, which allows founder teams to travel to MassChallenge’s U.S.-based hubs. The residency program already is underway in Houston and Boston.

In addition, founders will be able to take advantage of a newly created program that enables them to connect with MassChallenge stakeholders.

Last year, MassChallenge named 71 startups to its Houston cohort, and several walked away from the program with cash prizes. Per the nonprofit's website, there isn't a Houston-specific program planned for 2022. MassChallenge has had a presence in Houston since January of 2019 when it announced the Bayou City as a new market.

Note: This article originally identified seven Houston startups. The article has been updated to include the three Houston startups initially omitted.

Considering applying for something in this roundup of grants, accelerators, and more. Photo via Getty Images

4 Houston tech and startup opportunities to apply for

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A flurry of deadlines for grants, accelerators, and more are upcoming — do you have these on your radar?

Scroll through four tech and startup opportunities happening in Houston and open for Houston innovators.

MassChallenge and IBM's Mentorship Program for Underrepresented Founders

MassChallenge and IBM are bringing back a second cohort of their mentorship program, which provides AI mentoring support and resources to high-impact startups with historically underrepresented founders. In addition to artificial intelligence, IBM is expanding this program to invite startups innovating with cyber and data security.

The IBM Mentorship program will take place over the course of three months, starting May 11, and the early-stage startups enrolled in the program will be matched with IBM Mentors who will share their expertise helping them advance their businesses.

Select participating startups will be invited to participate in a Prize Competition where IBM will award $50,000 in non-cap-table cash prizes.

Applications for the IBM Mentorship program close at 11 pm April 13, 2022. Accepted startups will be notified by May 3, 2022. Apply now.

Additionally, MassChallenge has applications open for its international cohorts — including their Texas programs. The global network supports entrepreneurs and their startups through the early stages of building a business. Founded in 2009, MassChallenge’s non-profit, zero equity accelerator model supports more than 400 startups, from all industries and anywhere in the world, across seven locations and nine programs.

Eligibility requirements include:

  • Less than $1 million in funding (equity-based)
  • Less than $2 million in revenue
  • From any industry
  • From anywhere in the world
Applications are due April 20 at 11 am. Apply now.​

Small Business Growth Fund

Houston-based Hello Alice's Small Business Growth Fund provides the capital entrepreneurs need to make their next big move. Each recipient will receive a $5,000 grant to accelerate their growth and help make 2022 the year of their small business .Eligible businesses must:

  • Be a for-profit business
  • Have less than $1 million in 2021 gross annual revenue
  • Have a commitment to their customers and community
  • Have a clear plan for use of funds

If you applied and were not selected for a previous round of the program, you are welcome to submit a new application. The deadline for this application is May 20, 2022, at 5 p.m. Apply now.

M1 MedTech

Proxima Clinical Research's M1 MedTech, a medical technology accelerator, is accepting applications for its fall cohort. The accelerator is looking for five to seven of the most promising early-stage medical device companies to participate in its three-month program. The program has closed its first fund and will be selecting companies over the summer for investments up to $100,000 as a combination of both cash and in-kind services.

“Our program is unique in that it combines acceleration capital, company building expertise, and the regulatory and clinical services of a top CRO,” says Larry Lawson, a venture partner and investor with M1, in a news release. “Access to the M1 founders’ network, both within and outside of the Texas Medical Center, sets these companies up for success. There’s no better group to build a MedTech company with, period.”

Experts from Greenlight Guru, Medrio, Galen Data, and Merge Medical Device Studio join Proxima CRO as sponsors of the program and will assist with content delivery and mentoring. Applications will remain open until May 31. Apply now.

Deloitte's Technology Fast 500

Applications for Deloitte’s Technology Fast 500 are now open. Now in its 28th year, the ranking recognizes the most innovative, fastest-growing technology companies in North America across industries — media, life sciences, fintech, energy tech, and more.

“Each year, Houston’s Fast 500 applicants illustrate the important role innovation and technology play in our daily lives and in the advancement of our city,” says Amy Chronis, vice chair, oil, gas and chemicals leader, and Houston managing partner, Deloitte LLP. “We look forward to seeing the diverse portfolio of innovations Houston applicants bring to the table this year.”

To be eligible, companies must:

  • Be in business for at least four years
  • Be headquartered in North America
  • Have fiscal year 2018 operating revenues of at least US$50,000
  • Have fiscal year 2021 operating revenues of at least US$5 million
  • Have a growth rate of at least 75 percent (growth rate is computed as [(FY2021 rev. – FY2018 rev.)FY2018 rev.] x 100)
  • Own proprietary intellectual property or proprietary technology, which must be sold to customers in products or services that contribute to a majority of the company’s operating revenues

Past Houston-based winnersast Houston-based winners include Enercross LLC, Onit, and Graylog Inc.

The application period is open from April 4 to June 24. And winners will be announced on Nov. 16. Apply now.

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3 Houston innovators who made headlines in May 2025

Innovators to Know

Editor's note: Houston innovators are making waves this month with revolutionary VC funding, big steps towards humanoid robotics, and software that is impacting the agriculture sector. Here are three Houston innovators to know right now.

Zach Ellis, founder and partner of South Loop Ventures

Zach Ellis. Photo via LinkedIn

Zach Ellis Jr., founder and general partner of South Loop Ventures, says the firm wants to address the "billion-dollar blind spot" of inequitable distribution of venture capital to underrepresented founders of color. The Houston-based firm recently closed its debut fund for more than $21 million. Learn more.

Ty Audronis, CEO and founder of Tempest Droneworx

Ty Audronis, CEO and founder of Tempest Droneworx

Ty Audronis, center. Photo via LinkedIn.

Ty Audronis and his company, Tempest Droneworx, made a splash at SXSW Interactive 2025, winning the Best Speed Pitch award at the annual festival. The company is known for it flagship product, Harbinger, a software solution that agnostically gathers data at virtually any scale and presents that data in easy-to-understand visualizations using a video game engine. Audronis says his company won based on its merits and the impact it’s making and will make on the world, beginning with agriculture. Learn more.

Nicolaus Radford, CEO of Persona AI

Nicolaus Radford, founder and CEO of Nauticus RoboticsNicolaus Radford. Image via LinkedIn

Houston-based Persona AI and CEO Nicolaus Radford continue to make steps toward deploying a rugged humanoid robot, and with that comes the expansion of its operations at Houston's Ion. Radford and company will establish a state-of-the-art development center in the prominent corner suite on the first floor of the building, with the expansion slated to begin in June. “We chose the Ion because it’s more than just a building — it’s a thriving innovation ecosystem,” Radford says. Learn more.

Pharmaceutical giant plans $5.9B Houston facility and more news to know

Trending News

Editor's note: It's time to look back at the top Houston innovation news from the second half of May 2025. From exciting VC raises to major manufacturing facilities in the works, here are the most-read InnovationMap stories from May 16-30.

1. Pharmaceutical giant looks to bring $5.9 billion facility to Houston

Eli Lilly is looking to build an active pharmaceutical ingredient manufacturing facility at Generation Park. Rendering courtesy of McCord

Pharmaceutical company Eli Lilly and Company is looking to build a $5.9 billion active pharmaceutical ingredient (API) manufacturing facility in Houston, according to a recent filing with the state of Texas.

The proposal states that the project plans to employ 604 full-time direct employees at the site upon ramp-up completion. Construction is projected to begin in 2026, with a completion target of 2030 and commercial operations beginning in 2031. Continue reading.

2. Houston VC firm closes $21M fund for underrepresented founders

Zach Ellis, founder and general partner of South Loop Ventures, which recently closed its debut fund. Photo via LinkedIn

Houston-based South Loop Ventures recently closed its debut fund for more than $21 million, led by investments from Rice Management Company and Chevron Technology Ventures.

The funds will go toward teams with at least one underrepresented founder of color working in the energy, health, space, sports and fintech sectors. Additional investments came from The Great Commission Foundation of the Episcopal Diocese of Texas, Texas CapitalBank and others organizations. Continue reading.

3. Houston-founded startup raises $1.2M and moves headquarters to Detroit

ChurchSpace, founded in Houston by Day Edwards and Emmanuel Brown, is moving to Detroit. Photo courtesy ChurchSpace.

Houston-founded ChurchSpace, known as the Airbnb for churches, has formed an official partnership with the City of Detroit and will relocate its headquarters.

The announcements come as the company successfully closed a $1.2 million oversubscribed funding round. The round was led by California-based Black Ops Ventures, with participation from Michigan Rise and Dug Song of Minor Capital, who is also the founder of the Song Foundation, another Michigan-based organization. Continue reading.

4. Houston aerospace co. soars with first U.S. test flight of hypersonic engine

Venus Aerospace successfully completed the flight test of its hypersonic engine, the first of an American-developed engine of its kind. Photo courtesy Venus Aerospace

Houston-based Venus Aerospace successfully completed the first U.S. flight test of its proprietary engine at a demonstration at Spaceport America in New Mexico.

Venus’ next-generation rotating detonation rocket engine (RDRE) is supported by a $155,908 federal Small Business Innovation Research (SBIR) grant from NASA and aims to enable vehicles to travel four to six times the speed of sound from a conventional runway. The recent flight test was the first of an American-developed engine of its kind. Continue reading.

5. Houston regenerative medicine company expands lab for future trials

FibroBiologics has opened a new 10,000-square-foot Houston lab to scale up research efforts and pave the way for in-house manufacturing. Photo via Fibrobiologics.com

A Houston regenerative medicine company has unveiled new laboratory space with the goal of expanding its pioneering science.

FibroBiologics uses fibroblasts, the body’s most common type of cell, rather than stem cells, to help grow new cells. With its new space, the publicly traded company, which has more than 240 patents issued or pending, will be even better equipped to power forward with its research. Continue reading.

Houston university to launch artificial intelligence major, one of first in nation

BS in AI

Rice University announced this month that it plans to introduce a Bachelor of Science in AI in the fall 2025 semester.

The new degree program will be part of the university's department of computer science in the George R. Brown School of Engineering and Computing and is one of only a few like it in the country. It aims to focus on "responsible and interdisciplinary approaches to AI," according to a news release from the university.

“We are in a moment of rapid transformation driven by AI, and Rice is committed to preparing students not just to participate in that future but to shape it responsibly,” Amy Dittmar, the Howard R. Hughes Provost and executive vice president for academic affairs, said in the release. “This new major builds on our strengths in computing and education and is a vital part of our broader vision to lead in ethical AI and deliver real-world solutions across health, sustainability and resilient communities.”

John Greiner, an assistant teaching professor of computer science in Rice's online Master of Computer Science program, will serve as the new program's director. Vicente Ordóñez-Román, an associate professor of computer science, was also instrumental in developing and approving the new major.

Until now, Rice students could study AI through elective courses and an advanced degree. The new bachelor's degree program opens up deeper learning opportunities to undergrads by blending traditional engineering and math requirements with other courses on ethics and philosophy as they relate to AI.

“With the major, we’re really setting out a curriculum that makes sense as a whole,” Greiner said in the release. “We are not simply taking a collection of courses that have been created already and putting a new wrapper around them. We’re actually creating a brand new curriculum. Most of the required courses are brand new courses designed for this major.”

Students in the program will also benefit from resources through Rice’s growing AI ecosystem, like the Ken Kennedy Institute, which focuses on AI solutions and ethical AI. The university also opened its new AI-focused "innovation factory," Rice Nexus, earlier this year.

“We have been building expertise in artificial intelligence,” Ordóñez-Román added in the release. “There are people working here on natural language processing, information retrieval systems for machine learning, more theoretical machine learning, quantum machine learning. We have a lot of expertise in these areas, and I think we’re trying to leverage that strength we’re building.”

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