Jon Nordby's career has been focused on cultivating a culture for innovation, and now he's focused on human potential technology opportunities. Photo courtesy

In his role overseeing startup accelerators for MassChallenge, Jon Nordby started noticing one industry vertical stood out in terms of success and opportunities: Human potential. Now, Nordby is a founding member of an investment firm looking for those opportunities.

Nordby, who served in various leadership roles at MassChallenge — including managing director and head of ecosystems — said he started realizing the opportunities within the organization's space and sports tech programs.

"What we realized over a couple of years running the program was that sports tech as a theme was too limiting," Nordby says on the Houston Innovators Podcast. "We were finding really great technologies, but we were limited at the market size of teams and leagues to deploy those technologies."

"Over the course of that program, we found that the things that were related more to human health and performance tended to out perform all of the other things related to sports tech — like media, entertainment, gambling," Nordby continues. "Still really great markets for those technologies, but we found a lot more traction for human performance."

Nordby joined the team at Anthropy Partners, which exists to support early stage technologies that are advancing human mental and physical performance, a little over a year ago.

Defining human performance, Nordby says he thinks about it in terms of the hardware and software of a human, or physical and cognitive abilities — and how both sides of the equation work together.

"Some of the early investments that we've made have been in three realms — sensing, data, and analytics," Nordby explains, sharing examples from the Anthropy portfolio companies.

While Nordby jokes that his interest in human performance might confuse people who know him to be not particularly athletic, his other current roles fall more in line with his career history. A three-time startup founder, Nordby worked for the Greater Houston Partnership at the time the organization launched Houston Exponential. He left GHP to lead strategy for HX before transitioning to MassChallenge. All throughout these roles, Nordby has a front row seat for witnessing what it takes to develop innovation ecosystems.

He co-founded the Anthropy's nonprofit efforts for developing innovation ecosystems, called Anthropy Constructive. This year, he founded EconWerks, a for-profit company that advises entities on creating sustainable innovation efforts.

Nordby says he's "seen where things go wrong when people with really great intentions but not a lot of exposure or pattern recognition to ecosystem development are making investments or decisions on how those ecosystems need to develop."

Usually, Nordby explains, it's an economic development or ill-informed investment decision. But wrong moves can devastate a potential startup hub.

"Typically, when an investment is made and it doesn't pan out the way they think it should, there's typically a five to eight-year cycle of no more investments being made," Nordby says on the show. "When you think about the long-term effect that has on an innovation economy — an eight-year gap where you're not investing in startups — that's a problem."

Nordby thinks back to the goal setting Houston did several years ago, and reflects on how the ecosystem locally has evolved over the years.

"The goal we always set internally was to create a culture of innovation and to have the spirit of innovation permeate through the city," Nordby says. "Between 2016 when we started that initiative and that work until now, that culture is wildly different. ... The ecosystem has come a very, very long way in terms of attracting and encouraging founders."

Samra Nawaz founded WellWorth to tackle the convoluted financial modeling process in upstream oil and gas. Photo courtesy of WellWorth

How this Houston SaaS startup plans to scale with future of energy in mind

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As much as she loves a good Excel spreadsheet, Samra Nawaz had just about had it with the convoluted — and not always completely accurate — process of building financial models within upstream oil and gas.

"Excel is generally a good tool to automate workflows and build really robust spreadsheets. I live in Excel — I have a spreadsheet for everything," Nawaz says on the Houston Innovators Podcast. "What Excel is not is a database."

Engineering teams work with massive amounts with data that's too big for Excel, she explains, so finance teams then have to work off of aggregated data to build their financial models. She was ranting about why there isn't a better process to her husband, Vinay Acharya, who suggested that they build it themselves.



After thinking it through together, the duo co-founded WellWorth in 2018. Since then, the company has developed its MVP, completed a few accelerators — Rice University's OwlSpark, MassChallenge, and Softeq Ventures, to name a few — and won this year's Startup Pitch Competition hosted by the Ion.

Now, the bootstrapped startup looks to 2024 to bring on its first venture capital investors and team members — first to thoroughly tackle upstream O&G before expanding into other parts of the energy sector, including renewables.

"We're focusing on a specific workflow, and that is for engineering and finance teams and automating the corporate financial modeling side of the workflow," Nawaz says. "But we also see a lot of the renewables companies sprouting up, and we understand the attention on renewables verticals is only going to increase in the next few years.

"We're building WellWorth in a very modular way, so that when the time is right, we can easily start working with customers in the renewable space as well," she adds.

Nawaz, CEO of WellWorth, shares more about her company's growth plan and the impact the technology has on its early customers on the podcast.

WellnessWits, founded by Kike Oduba to enhance patient-physician interaction, has integrated AI with the help of IBM. Photo via WellnessWits.com

Houston health tech startup taps into IBM tech for AI integration

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A Houston startup aimed at transforming healthcare with solutions for chronic disease and its prevention has teamed up with IBM technology.

WellnessWits has embedded IBM watsonx Assistant into its app for both iOS and Android. By making generative AI part of the app, WellnessWits now boasts an AI-based chat functionality.

That cutting-edge aspect of the platform allows patients to get information on chronic disease more quickly than ever, even before meeting with their physician. But it helps with that, too, aiding in scheduling appointments more easily with doctors who specialize in a host of chronic maladies.

“I founded WellnessWits as a platform for shared medical appointments where doctors with large patient loads can see them in groups and offer collective shared medical experiences to people suffering from chronic conditions. The goal is to bridge this divide, leveraging the strength of digital communities to enhance the overall well-being and healthcare experiences of individuals everywhere,” WellnessWits Founder and CEO Dr. Kike Oduba, a physician and informatician, writes in a blog post.

Oduba founded the company in 2018. In its early years, she participated in IBM’s First AI Cohort for Underrrepresented Founders Program. She believes that by using watsonx Assistant in her technology arsenal, WellnessWits will be a means to “digitize, standardize and automate care plans for patients dealing with chronic diseases.”

Diabetes management is a cornerstone of the company, but Oduba says that WellnessWits is similarly committed to impacting health issues including cancer, chronic pain, mental health, and obesity.

“By partnering with IBM, and academic leaders in institutions like The University of Texas, we aim to extend our reach and impact,” Oduba says.

In addition to the IBM program, Oduba and WellnessWits was selected for MassChallenge's recent cohort.

MassChallenge Startup Stories: WellnessWits Founder's Journey from Struggles to SuccessIn this inspiring 6-minute testimonial, we take you through the remarkable experience of Dr. Oduba, founder and CEO of ...

Houston founders — these four programs have applications open now. Photo via Getty Images

4 program deadlines Houston innovators should know about

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Editor's note: It's safe to say 2023 has fully kicked off as Houston's startup and innovation ecosystem has switched into second gear. A handful of programs — local and national — have opened applications for accelerators and pitch competitions. Scroll through to find one that applies to your company or a startup you know of. Take careful note of the deadlines since they'll be here before you know it.

Is something missing? Email natalie@innovationmap.com for editorial consideration.

Carbon to Value Initiative

Greentown Labs announced its looking for innovative companies with carbon-related technology. Photo via GreentownLabs.com

Greentown Labs announced that its Carbon to Value (C2V) Initiative has opened applications for its third set of startups.

"Supported by the New York State Energy Research and Development Authority, the C2V Initiative is a unique partnership among the Urban Future Lab at NYU Tandon School of Engineering, Greentown Labs, and Fraunhofer USA that’s driving the creation of a thriving innovation ecosystem for the commercialization of carbontech—technologies that capture and convert CO₂ into valuable end products or services," reads the news release. "Since the C2V Initiative's inception in 2020, the program has supported 18 groundbreaking carbontech startups—chosen from an exceptional pool of more than 230 applications."

The program is looking for companies with technologies within carbon capture, management, removal, or conversion and between TRL 4 and TRL 7. Selected companies will receive a $10,000 stipend and participate in the six-month program.

Applications are due by the end of the day on March 31. For more information and to apply, click here.

MassChallenge accelerators

MassChallenge has two accelerators open for applications. Photo courtesy of MassChallenge

MassChallenge has two programs with open applications:

MassChallenge US Early Stage Accelerator (Deadline: March 3)

This three-month program is industry agnostic and provides intensive support, guidance, tools, and connectivity to the greater MassChallenge community. Around 200 startups are selected per cohort that range in stage from those currently engaged in customer discovery work to validating a technology or service. For more information and to apply, click here.

MassChallenge HealthTech Accelerator (Deadline: February 6)

The 2023 HealthTech Sprint is an eight-week program intended to work intensely with 20 to 25 startups to accelerate the tools and technologies that could transform healthcare. The HealthTech Sprint program is designed to support mid-stage companies that possess a product/solution ready for scaling. For more information and to apply, click here.

Houston Energy Transition Initiative's Energy Ventures Pitch Competition 

HETI is bringing back its CERAWeek pitch competition. Image via houston.org

The Greater Houston Partnership's Houston Energy Transition Initiative, or HETI, is looking for participants for its Energy Ventures Pitch Competition at CERAWeek this year.

"This pitch competition brings together key members of the energy industry, investors, and startups to showcase the critical innovations and emerging technologies that create value from the world’s transition to low-carbon energy systems," reads the website.

HETI is looking for companies addressing challenges and opportunities in CCUS, hydrogen, energy storage, and the circular economy, are invited to present their well-developed business concepts to a world-class investor community.

Applications close February 9. For more information and to apply, click here.

Rice Business Plan Competition

The annual Rice Business Plan Competition has opened applications for student startups. Photo by Natalie Harms

Calling all student-founded startups — the largest and richest intercollegiate student startup competition, the Rice Business Plan Competition, has applications open. According to Rice, 784 RBPC alumni have raised $4.6 billion in funding and created over 5,500 jobs. This year's event is going to be held May 11 to 13.

The RBPC is open to all students from any university around the world. Teams must include at least one graduate-level student, and every team that is invited to compete in person at Rice University is guaranteed to take home at least one of the more that 60 expected cash prizes. For more information and to apply, click here.

MassChallenge has selected 10 Houston startups to participate in its 2022 United States cohort. Photo courtesy of MassChallenge

MassChallenge names 10 Houston companies to national cohort

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Ten Houston companies have been chosen for MassChallenge’s 2022 United States cohort of early-stage startups.

The 10 Houston startups are:

  • BEMY Cosmetics, a maker of skin rejuvenation products based on RNA technology
  • Eisana Corp., whose products are designed to ease the side effects of breast cancer treatment
  • Enrichly, a self-esteem-based e-learning platform and gaming app
  • RE.STATEMENT, an online marketplace for upcycled clothing
  • Roxie Health, a virtual medical assigned geared toward preventing falls by seniors
  • Vivifi Medical, whose laparoscopic technology treats male infertility and prostate gland enlargement
  • Vouchpad, a provider of affordable student loans
  • Equiliberty, an equitable fintech platform focused on creating generational wealth
  • National Police Data, an organization creating an index of Police data in America
  • Cryodesalination, a new low cost desalination process focused on providing access to fresh water

In all, the MassChallenge innovation network selected 250 early-stage startups for this fall’s U.S. accelerator program in Houston, Austin, Dallas, Boston, and Providence, Rhode Island. Participants are eligible for equity-free cash prizes of as much as $1 million. MassChallenge is open to early-stage startups that have raised less than $1 million in equity funding and have generated less than $2 million in revenue over the past 12 months.

“We’re in the business of solving massive challenges, and to do that, we must continue to support diverse founders with bold ideas across geographies, industry verticals, and demographics in creative ways that allow them to wholly own their ideas and solve some of our world’s most pressing problems,” Hope Hopkins, head of acceleration at MassChallenge, says in a news release.

This year’s cohort will have access to MassChallenge’s new residency program, which allows founder teams to travel to MassChallenge’s U.S.-based hubs. The residency program already is underway in Houston and Boston.

In addition, founders will be able to take advantage of a newly created program that enables them to connect with MassChallenge stakeholders.

Last year, MassChallenge named 71 startups to its Houston cohort, and several walked away from the program with cash prizes. Per the nonprofit's website, there isn't a Houston-specific program planned for 2022. MassChallenge has had a presence in Houston since January of 2019 when it announced the Bayou City as a new market.

Note: This article originally identified seven Houston startups. The article has been updated to include the three Houston startups initially omitted.

Considering applying for something in this roundup of grants, accelerators, and more. Photo via Getty Images

4 Houston tech and startup opportunities to apply for

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A flurry of deadlines for grants, accelerators, and more are upcoming — do you have these on your radar?

Scroll through four tech and startup opportunities happening in Houston and open for Houston innovators.

MassChallenge and IBM's Mentorship Program for Underrepresented Founders

MassChallenge and IBM are bringing back a second cohort of their mentorship program, which provides AI mentoring support and resources to high-impact startups with historically underrepresented founders. In addition to artificial intelligence, IBM is expanding this program to invite startups innovating with cyber and data security.

The IBM Mentorship program will take place over the course of three months, starting May 11, and the early-stage startups enrolled in the program will be matched with IBM Mentors who will share their expertise helping them advance their businesses.

Select participating startups will be invited to participate in a Prize Competition where IBM will award $50,000 in non-cap-table cash prizes.

Applications for the IBM Mentorship program close at 11 pm April 13, 2022. Accepted startups will be notified by May 3, 2022. Apply now.

Additionally, MassChallenge has applications open for its international cohorts — including their Texas programs. The global network supports entrepreneurs and their startups through the early stages of building a business. Founded in 2009, MassChallenge’s non-profit, zero equity accelerator model supports more than 400 startups, from all industries and anywhere in the world, across seven locations and nine programs.

Eligibility requirements include:

  • Less than $1 million in funding (equity-based)
  • Less than $2 million in revenue
  • From any industry
  • From anywhere in the world
Applications are due April 20 at 11 am. Apply now.

Small Business Growth Fund

Houston-based Hello Alice's Small Business Growth Fund provides the capital entrepreneurs need to make their next big move. Each recipient will receive a $5,000 grant to accelerate their growth and help make 2022 the year of their small business .Eligible businesses must:

  • Be a for-profit business
  • Have less than $1 million in 2021 gross annual revenue
  • Have a commitment to their customers and community
  • Have a clear plan for use of funds

If you applied and were not selected for a previous round of the program, you are welcome to submit a new application. The deadline for this application is May 20, 2022, at 5 p.m. Apply now.

M1 MedTech

Proxima Clinical Research's M1 MedTech, a medical technology accelerator, is accepting applications for its fall cohort. The accelerator is looking for five to seven of the most promising early-stage medical device companies to participate in its three-month program. The program has closed its first fund and will be selecting companies over the summer for investments up to $100,000 as a combination of both cash and in-kind services.

“Our program is unique in that it combines acceleration capital, company building expertise, and the regulatory and clinical services of a top CRO,” says Larry Lawson, a venture partner and investor with M1, in a news release. “Access to the M1 founders’ network, both within and outside of the Texas Medical Center, sets these companies up for success. There’s no better group to build a MedTech company with, period.”

Experts from Greenlight Guru, Medrio, Galen Data, and Merge Medical Device Studio join Proxima CRO as sponsors of the program and will assist with content delivery and mentoring. Applications will remain open until May 31. Apply now.

Deloitte's Technology Fast 500

Applications for Deloitte’s Technology Fast 500 are now open. Now in its 28th year, the ranking recognizes the most innovative, fastest-growing technology companies in North America across industries — media, life sciences, fintech, energy tech, and more.

“Each year, Houston’s Fast 500 applicants illustrate the important role innovation and technology play in our daily lives and in the advancement of our city,” says Amy Chronis, vice chair, oil, gas and chemicals leader, and Houston managing partner, Deloitte LLP. “We look forward to seeing the diverse portfolio of innovations Houston applicants bring to the table this year.”

To be eligible, companies must:

  • Be in business for at least four years
  • Be headquartered in North America
  • Have fiscal year 2018 operating revenues of at least US$50,000
  • Have fiscal year 2021 operating revenues of at least US$5 million
  • Have a growth rate of at least 75 percent (growth rate is computed as [(FY2021 rev. – FY2018 rev.)FY2018 rev.] x 100)
  • Own proprietary intellectual property or proprietary technology, which must be sold to customers in products or services that contribute to a majority of the company’s operating revenues

Past Houston-based winnersast Houston-based winners include Enercross LLC, Onit, and Graylog Inc.

The application period is open from April 4 to June 24. And winners will be announced on Nov. 16. Apply now.

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Experts: Houston's VC ecosystem has set the foundation — now we need scale

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Fervo Energy went public earlier this summer. The Houston geothermal company priced its IPO at $27 per share, raised $1.89 billion, and opened the next morning at a market capitalization north of $10 billion. By most measures, it is the largest venture-backed cleantech IPO in history and an unambiguous win for Houston. It’s also a useful moment to look at where Houston's venture ecosystem stands and where it can go. The highlight: Houston's venture ecosystem has real foundations and, with increased company formation activity, can grow into the scale our city's ambitions deserve.

A Houston energy story in the national recovery

The recent uptick in Houston venture activity follows national trends. U.S. venture deal count contracted roughly 22 percent from its 2021 peak through 2024 before rebounding to about 16,700 rounds in 2025. Houston's 23 percent increase in VC funding from 2023 to 2024 is part of a national recovery of comparable magnitude over the same time window.

The energy sector is where Houston exhibits unique trends—and where the story turns clearly positive. (Houston's strong health and space sectors deserve their own separate consideration.) By deal count, energy-related rounds have accounted for 15 to 20 percent of Houston activity, roughly consistent over the past few years.

By capital, energy's share surged from about 14 percent in 2023 to over 60 percent in 2025, driven by a small number of large Houston-headquartered rounds, primarily in geothermal and related technologies. Fervo is the obvious anchor, but Sage Geosystems, Quaise Energy, Zeta Energy, Vaulted Deep, Applied Carbon and Mariana Minerals have all closed meaningful rounds. Houston is concentrated and accelerating as an energy capital market, an invaluable position to build upon.

From foundation to scale

The institutional pieces are in place. Greentown Labs, Activate, the Ion and others have built sector-specialized infrastructure most cities would struggle to assemble. Fervo itself is an alum of both Activate and Greentown Labs. Mercury Fund closed its $160 million Fund V, its largest ever. Houston Angel Network, GOOSE Capital, Fathom Fund, and broader pre-seed and seed capital coverage are here. The Houston $10 million-plus Series A list now includes 40 rounds since 2021, which break roughly into two eras. While 2021 to 2022 was biotech-heavy, with companies like Sporos Bioventures, RadioMedix, Cellenkos and Coya Therapeutics, 2024 to 2025 has tilted clearly toward energy, climate, and critical minerals, with Vaulted Deep, Applied Carbon, Mariana Minerals, Sage Geosystems and Ignis H2 Energy among them.

What’s less developed is the volume of seed-stage companies flowing into that capital. Imagine a dozen more Fervos coming out of that infrastructure over the next decade, each generating jobs, recycled founder capital, and the next wave of operators and angel investors. That is the kind of opportunity Houston has within reach if we build the company-formation pipeline to feed it. To be relevant on the national stage as a venture market, and to drive an economy the size of Houston's into the 2030s, the city needs to be doing closer to 20 Series A rounds per month rather than per year. That throughput implies roughly 1,000 seed rounds per year, feeding the funnel at a 20 percent to 30 percent graduation rate. Reaching such throughput depends on how many new founders Houston produces and how quickly our innovation ecosystem can help them achieve lift-off.

Houston in context

The comparative picture brings the scaling challenge into focus. Between 2021 and 2024, Houston-area startups closed between 126 and 153 disclosed venture rounds per year, against a national count between 9,854 and 14,125. That places Houston at a little over 1 percent of the U.S. deal count. For comparison, Austin ran about three times Houston's deal count each year.

At the Series A level, Houston closed between 12 and 24 rounds in any given year. The median Houston Series A across the period was about $10.7 million, compared with $15.4 million in San Francisco. Houston founders are raising fewer and smaller Series A rounds than founders in peer metros, which points directly to where Houston has the most room to grow.

The unicorn picture tells the same story. From 2021 through 2025, the U.S. produced 590 venture-backed unicorns. Four were Houston-based: Solugen and Axiom Space in 2021, Cart.com in 2023, and Fervo Energy in 2024. Adding HighRadius from 2020 brings Houston's all-time total to five. Austin added 19 over the same five-year window. The path from here is to make Houston's entries on lists like these less the exception and more the rule.

Where this leads

Houston has a real opportunity to become the deepest, most credible energy and climate capital market in the country, with the company formation, talent and operator density to support it. The data shows the foundation is already in place. Fervo, Solugen and the growing roster of energy-adjacent Series A graduates are proof. Fervo's IPO is the first of what should be many. Houston has not had a venture-backed cleantech liquidity event of this scale before, and the city now has one to reference, recruit against and build on. With increased company formation at the seed and pre-seed stages, a Fervo-scale outcome need not be a generational event in Houston, but instead, it can become part of a chain reaction powering the city's economy.

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Stephanie T. Schmidt, PhD, is a Venture Fellow at Energy Transition Ventures and an Executive MBA candidate at Rice University. Lawson Gow is the Chief Operating Officer of Greentown Labs. The full Houston VC landscape report is available at Energy Transition Ventures and CleanTech.org.

Sources: Crunchbase, PitchBook-NVCA, Carta

8 can't-miss Houston business and innovation events for July

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Editor's note: Summer is in full swing in Houston, but the city's innovation ecosystem isn't slowing down. This month brings AI workshops, energy and manufacturing discussions, entrepreneur-focused networking, and opportunities to connect with investors and industry leaders. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.

July 7 — How Oil and Gas Professionals are Building Wealth Smarter

Hear from oil and gas professionals on how to preserve wealth at this event put on by Financial Advice Center. The conversation will touch on topics like investing, taxes and retirement planning.

This event is Tuesday, July 7, from noon-1 p.m. at the Ion. Register here.

July 7 — What AI, Cybersecurity, and Tequila Have in Common.

Join Blue People and Alpfa Houston for this engaging presentation on the advantages and risks associated with AI at the latest installment of Tech + Tequila Talk. Cybersecurity veteran Reynaldo Gonzalez will lead the conversation.

This event is Tuesday, July 7, from 5-7 p.m. at the Ion. Register here.

July 7 — Speed to Market: Houston’s Advanced Manufacturing Edge

The Greater Houston Partnership presents a forum that explores what allows advanced manufacturing projects in Houston to move from concept to operation, where delays and bottlenecks occur, and more. Industry leaders Jennifer Clement from CliftonLarsonAllen LLP and Sarah Janes from San Jacinto College will lead the discussion.

This event is Tuesday, July 7, from 11:30 a.m.-1 p.m. at the Partnership Tower. Register here.

July 9 — Capital Connections Summit

Houston City College Center for Entrepreneurship will host the Capital Connections Summit this month, with a panel discussion focused on access to capital and technical assistance for small businesses and entrepreneurs. The event will be moderated by the U.S. Small Business Administration Houston District Office and will feature lenders, nonprofit microlenders, business advisors, and entrepreneurial support organizations. A live Q&A will follow the panel.

This event is Thursday, July 9, from 11 a.m.-1:30 p.m. at Houston City College Central Campus. Register here.

July 9 — Upstream: Digital Tech Meetup at Second Draught

Join Timbergrove at this month's gathering of energy, operations and technology professionals from across the upstream ecosystem. Discuss challenges, explore new ideas and network over pizza and beer at Second Draught.

This event is Thursday, July 9, from 5:30–8 p.m. at the Ion. Register here.

July 14 — Why Networking Isn’t Turning Into Deals, And What To Do Instead

Jada Powell, founder of Powell Consulting Group, will break down why networking often fails to convert into deals and what companies can do differently to turn conversations into qualified opportunities. Powell works with oil and gas, energy, and industrial companies on business development solutions. This session is part of the monthly Pipeline Series: How Oil & Gas Companies Actually Grow Revenue.

This event is Tuesday, July 14, from noon-1 p.m. at the Ion. Register here.

July 15 — From Pilot to Performance: Building Your AI Procurement Roadmap

It's not too late to join in on the GHP's two-part AI series on moving from experimentation to implementation. In session two, explore how procurement and supply chain leaders can scale AI responsibly to create long-term business value. This event will be led by Cassye Cook Provost, founder and principal of RossGrigsby Consultancy.

This virtual event is Wednesday, July 15, from 8:30-10 a.m. Register here.

July 30 — Rice University Summer Engineering Innovation Program - Demo Day 2026

Meet the young minds and see the final team project presentations from Rice University’s Summer Engineering Innovation Program. The 10-week program challenges Rice students to solve real-world challenges using AI, digital engineering, model-based systems engineering and Industry 4.0 technologies.

This event is Thursday, July 30, from 6-8 p.m. at the Ion. Find more information here.