Spring-based ExxonMobil ranks within the top 10 on the new Fortune AIQ 50 ranking. Photo via Getty Images.

Three companies based in the Houston area appear on Fortune’s inaugural list of the top adopters of AI among Fortune 500 companies.

The three companies are:

  • No. 7 energy company ExxonMobil, based in Spring
  • No. 19 tech company Hewlett Packard Enterprise, based in Spring
  • No. 47 energy company Chevron, based in Houston

All three companies have taken a big dive into the AI pool.

In 2024, ExxonMobil’s executive chairman and CEO, Darren Woods, explained that AI would play a key role in achieving a $15 billion reduction in operating costs by 2027.

“There is a concerted effort to make sure that we're really working hard to apply that new technology to the opportunity set within the company to drive effectiveness and efficiency,” Woods told Wall Street analysts.

Hewlett Packard Enterprise is also employing AI to decrease costs. In March, the company announced a restructuring plan — including the elimination of 3,000 jobs — aimed at cutting about $350 million in annual expenses. The restructuring is scheduled to wrap up by the end of October.

Hewlett Packard Enterprise’s Catalyst cost-cutting program includes a push to use AI across the company to improve efficiency, Marie Myers, the company’s executive vice president and chief financial officer, told Wall Street analysts in June.

“Our ambition is clear: A leaner, faster, and more competitive organization. Nothing is off limits. We are focused on rethinking the business — not just reducing our costs, but transforming the way we operate,” Myers said.

At Chevron, AI tools are being used to quickly analyze data and extract insights from it, according to tech news website VentureBeat. Also, Chevron employs advanced AI systems known as large language models (LLMs) to create engineering standards, specifications and safety alerts. AI is even being put to work in Chevron’s exploration initiatives.

Bill Braun, Chevron’s chief information officer, said at a VentureBeat-sponsored event in 2024 that AI-savvy data scientists, or “digital scholars,” are always embedded within workplace teams “to act as a catalyst for working differently.”

The Fortune AIQ 50 ranking is based on ServiceNow’s Enterprise AI Maturity Index, an annual measurement of how prepared organizations are to adopt and scale AI. To evaluate how Fortune 500 companies are rolling out AI and how much they value AI investments, Fortune teamed up with Enterprise Technology Research. The results went into computing an AIQ score for each company.

At the top of the ranking is Alphabet (owner of Google and YouTube), followed by Visa, JPMorgan Chase, Nvidia and Mastercard.

Aside from ExxonMobil, Hewlett Packard Enterprise, and Chevron, two other Texas companies made the list: Arlington-based homebuilder D.R. Horton (No. 29) and Austin-based software company Oracle (No. 37).

“The Fortune AIQ 50 demonstrates how companies across industry sectors are beginning to find real value from the deployment of AI technology,” Jeremy Kahn, Fortune’s AI editor, said in a news release. “Clearly, some sectors, such as tech and finance, are pulling ahead of others, but even in so-called 'old economy' industries like mining and transport, there are a few companies that are pulling away from their peers in the successful use of AI.”

In honor of Labor Day, here are three Houston innovators who probably aren't taking the day off. Courtesy photos

3 Houston innovators to know this week

Who's who

It may be Labor Day, but some of the hardest working Houston innovators are probably still checking their email on their phones from the pool.

Here are this week's innovators to know around town.

Marie Myers, CFO of UiPath

Marie Myers is the CFO of UiPath. Courtesy of UiPath

Marie Myers is a self-proclaimed Houstonian, avid bike rider, and robotics nerd — for lack of a better word. She's had a 20-year career in tech — most roles based right here in town — and throughout her whole experience, robotics process automation has been the most exciting technology she's gotten to work with.

UiPath just opened an office in Houston earlier this year, and Myers serves the company as CFO. She first worked with UiPath on the client side of things, and the technology awed her. She says she jumped at the opportunity to join the organization.

"When I think about RPA, the world lights up for me," she says. "It's truly transformative."

Click here to read more about the company.

Marco Bo Hansen, chief customer officer at Sani nudge and his executive team

Marco Bo Hansen, right, the chief customer officer at Sani nudge. Courtesy of TMCx

The Sani nudge executives may not be from Houston, but we give the Denmark-based company a pass for all its success coming out of the Texas Medical Center's accelerator program earlier this year. Sani nudge is a medical device company that can better track and encourage hand sanitation. The company is headed to California after being selected for a prestigious program with the Mistletoe Foundation.

Dr. Marco Bo Hansen is the chief customer officer and says that he'll be vigilantly advocating that his Sani nudge colleagues and the Mistletoe researchers keep hospital patients and staff in mind as Sani nudge moves forward with its innovations.

"We have to make sure that our solutions always generate value to the end users and can easily be used by the clinicians, infection preventionists, and hospital managers," he says.

Click here to read more about the company.

Ashley Gilmore, CEO and co-founder of Tracts.co

When Ashley Gilmore was studying law — specifically for the purposes of going into oil and gas — it amazed him how non-digitized the industry was, especially the mineral buying process. Gilmore figured out a way how to use tech to make the process way easier — and cheaper.

Now, his company, Tracts, has a new land group that's growing at a revenue rate of 30 percent month to month. With more and more clients, Tracts engages more data. And, with more and more data, the product increases in value for his customers.

"For some of our clients, Tracts is now existential for their business," Gilmore says. "In other words, they wouldn't be able to operate on their current business model without Tracts."

Click here to read more about the company.

Marie Myers is the CFO of UiPath and is based in the company's new Houston office. Courtesy of UiPath

Robotics exec talks plans for new Houston office and the future of automation

robot revolution

It's safe to say that Marie Myers — CFO of UiPath, which opened its 71-person office in Houston earlier this year — loves her job.

The robotics process automation company, which was founded in Romania before moving its headquarters to New York City last year, is in major growth mode. At the helm of the financial side of things is Myers, who has over 20 years of experience in technology.

When Myers was working on a spinoff project for HP, she started seeing the difference software automation makes on a company's bottom line.

"I realized RPA was the fastest way to drive efficiencies, so I started building bots," she tells InnovationMap. "During that time, I came across UiPath and I saw how impressive their technology was. In my more than two-decade career, I hadn't really come across a technology that I felt that had such an impressive impact in such a short time."

She drank the UiPath Kool-Aid, and when the company came to her adopted hometown of Houston to open an office to be its central, Midwestern location, she leapt at the opportunity to join the team. Now, with several months under her belt in the position and a growing office, Myers speaks with InnovationMap about the company's growth and the revolution that RPA is having in business.

InnovationMap: You've been in your role since January, but you've been in tech for a while now. How has the transition been for you?

Marie Myers: This has been one of the most exciting times for my career. I've been in tech for about two decades. I started with Compaq — quite an incredible company that started right here in Texas. It was a very famous startup in its own time, and I had a chance to be a part of that wave, which was really incredible. Then, it got bought out by HP, and then I pivoted and spent a lot of time in Silicon Valley for a couple decades.

I got involved in robotics process automation quite by happenstance about four years ago when HP decided to split. I was involved in setting up a company from the finance and legal perspective. I got challenged to drive some cost efficiency, so I turned to RPA as a means to drive some of that impact within my own organization of a couple thousand folks.

When the opportunity came up to be CFO for UiPath, I really jumped at it because it filled two important things for me. I wanted to be a leader of a finance organization and team. Secondly, I wanted to do something where I was really passionate about the technology. When I think about RPA, the world lights up for me. It's truly transformative.

IM: How did UiPath decide to open a Houston office? What made the city a key market?

MM: Houston — particularly Texas — are both important for us, from a customer perspective. We have some of our larger companies in the country here in Texas, so it was a natural place to look to build capability. Secondly, we're impressed with the overall quality of the market and the availability of different skills here as we build out our company.

IM: What are some goals UiPath has for its new Houston office?

MM: Overall, one of the key goals is to establish a strong Midwest presence for the company. Texas is an ideal location if you think about it for customers that range from the East to the West. Being in the middle is a good, central location. Also, as we grow and expand in Latin America, it's another interesting spot for us. So, one, to ensure that we are able to support the growth needs of the company throughout the United States and leverage the strategic location that Texas has.

I think the other goal is to build some of the core skills we need for the overall organization as we grow in the United States. UiPath is a relatively new player in the U.S., only been here a couple of years.

Finally, we've got terrific customers here, so what's important is to continue to support and nurture those customers. We have a big presence in oil and gas and the support companies within energy.

IM: Tell me about the Academic Alliance and how the company engages with students.

MM: Basically, we offer free training to the universities so that students can get first-hand experience for robotics process automation, which is part of our broader commitment we've made to ensure RBA is available in an open, democratized way.

We are big proponents of supporting students, and we had a great intern program this last summer. We had a double-digit number of interns — I think the largest population in the U.S. We love the fact that we have this access to universities that we can easily tap into.

Just a couple weeks ago we ran UiPath's first-ever hackathon for students in the United States. We had over 50 participants.

We're really excited about building out the ecosystem with the universities and the students here in Houston.

IM: What sort of misconceptions do you encounter within automation?

MM: First and foremost, a lot of it is misconceptions about RPA replacing jobs. I'd say it's a shift in the workforce — I witness this first hand because I had a team where we implemented and built bots. What happens is you create capacity and end up creating new jobs. You have roles of managing bots, bot controllers, bot librarians — these are roles that fundamentally didn't exist five years ago.

IM: What advice do you have for women in tech?

MM: I think it's so critical for women to be in the driving seat and in the forefront of technology. I have two daughters and I'm adamant about how they are exposed to robotics. I did a coffee talk in Houston not too long ago, and I really challenged the women to get out there and get digitally literate. It's really important as women that we don't let ourselves fall behind on technology and how they are impacting both our work and our families. So, staying informed, no matter how you do that — reading, podcasts, news. Another way is to join and network with associations. Myself and another woman important in this space are looking to create a network for women in automation. We want to build a group that will allow women to look for jobs, board roles, mentors, etc. in this industry.

IM: What role do you see Houston playing in the greater innovation conversation and where does the city have room to improve?

​MM: I'm a big fan of Houston. I'm Australian, but I feel like a Texas implant now. It's an incredibly diverse city, and I think that's one of its greatest strengths. You've got people from all walks of life from all parts of the world and a great education system. That creates a really unique backdrop for the technology-led era we're in. The historical strengths of the city have been predicated on the healthy oil and gas sector and medical sector — both are important industries going through major technology transformations. I think for Houston being able to capitalize on all that is a very unique opportunity. It will position Houston very well for the future. You've got the right ingredients here.

Where the city is going to have to continue to build is specifically around some of these skills for the future. Artificial intelligence and having that depth of experience is an area the city struggles in. Certainly other cities like Seattle and San Francisco have tens of years of experience from companies like Google, Facebook, and Amazon that have been able to build deep AI. In Houston, that skillset is going to come more from oil and gas, where they've been building some of those skills, just not in the same breath and not in the same depth as those other cities. I think the real opportunity is to nourish and nurture this in the academic institutions and then take that talent out of the academic institutions and integrate them into the corporations.

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Portions of this interview have been edited.

UiPath's Houston office is in a historic downtown Houston building that's been renovated. Courtesy of Main&Co

Global automation company doubles down on Houston as it grows its United States presence

New bot on the block

When UiPath decided to look into an office in Houston, it was a bit of a gamble, since Houston's not particularly known for its wealth of hardware talent.

"We did a little bit of an experiment to see what the skills would be like specifically in a Houston office," Marie Myers, CFO of the company and based in Houston, tells InnovationMap. "As a robotics company, we weren't sure if we'd get more of those software skills. It's not a natural market for those skills."

But Houston — and Texas in general — is a great location for the robotics process automation company, Myers says. It's central and optimal for customer acquisition. Valued at $7 billion, UiPath has over 2,500 customers — adding six more a day on average, according to a news release.

Since beginning Houston operations in January, Myers says she's very pleased with the 71-person team the company has assembled locally, and the company has even expanded in that short time. Following a $568 million Series D round closing, the company almost doubled its office size.

"The Series D is critical for us as we continue to grow and we're using those proceeds to grow our base across the world, and obviously part of the Houston expansion has been just that," Myers says.

UiPath plans to really settle into Houston and even bring a an RPA Immersion Lab into its Houston office. The lab would allow for potential customers to try out the technology and run simulations. The lab is on the docket for 2020, Myers says.

Another way UiPath is engaging with the Houston community is through its connection to students and universities. The company has an arrangement with six universities in Houston and is even located just across the street from the University of Houston-Downtown. Myers says the company had one of its largest group of interns working in Houston.

"It's going to be so important for students graduating to have experience in up-and-coming technologies, like RPA," Meyers says. "We see such great support from the local universities."

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Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.

5 incubators and accelerators fueling the growth of Houston startups

meet the finalists

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.