This week's roundup of Houston innovators includes Hannah Le of RE.STATEMENT, Misha Govshteyn of MacroFab, and Kelli Newman of Newman & Newman Inc. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from sustainable fashion to tech manufacturing — recently making headlines in Houston innovation.

Hannah Le, founder of RE.STATEMENT

Hannah Le founded RE.STATEMENT to provide a much-needed platform for sustainable fashion finds. Photo courtesy of RE.STATEMENT

It's tough out there for a sustainable fashion designer with upcycled statement pieces on the market. First of all, there historically hasn't been a platform for designers or shoppers either, as Hannah Le explains on this week's episode of the Houston Innovators Podcast.

"Most designers give up if they haven't sold an item within three months," Le says. "That's something RE.STATEMENT has dedicated its business model to — making sure that items sell faster and at a higher value than any other marketplace."

RE.STATEMENT won one of the city of Houston's startup competition, Liftoff Houston's categories last year. Le shares what's next for the early-stage company on the show. Read more and listen to the episode.

Misha Govshteyn, CEO of MacroFab

MacroFab has secured fresh investment to the tune of $42 million. Photo courtesy of MacroFab

MacroFab, a Houston-based electronics manufacturing platform, has announced $42 million in new growth capital. The company was founded by Misha Govshteyn and Chris Church, who built a platform that manage electronics manufacturing and enables real-time supply chain and inventory data. The platform can help customers go from prototype to high-scale production with its network of more than 100 factories across the continent.

“Electronics manufacturing is moving toward resilience and flexibility to reduce supply chain disruptions,” says Govshteyn, MacroFab’s CEO, in a news release. “We are in the earliest stages of repositioning the supply chain to be more localized and focused on what matters to customers most — the ability to deliver products on time, meet changing requirements, and achieve a more sustainable ecological footprint. MacroFab is fundamental to building this new operating model.”

The company has seen significant growth amid the evolution of global supply chain that's taken place over the past few years. According to the company, shipments were up 275 percent year-over-year. To keep up with growth, MacroFab doubled its workforce, per the release, and opened a new facility in Mexico. Read more.

Kelli Newman, president of Newman & Newman Inc.

In her guest column, Kelli Newman explains how to leverage communications at any stage your company is in. Photo courtesy of Newman & Newman

Kelli Newman took actionable recommendations from investors, customers, advisers, and founders within Houston to compose a guest column with key observations and advice on leveraging communications.

"The significance of effective communication and its contribution to a company’s success are points regularly stressed by conference panelists and forum speakers," she writes. "Yet for many founders it’s advice that fuels frustration for how to make communications a priority with a lack of understanding of the practice." Read more.

MacroFab has secured fresh investment to the tune of $42 million. Photo via macrofab.com

Tech-enabled manufacturing startup based in Houston secures $42M in growth financing

show me the money

A Houston company has nearly doubled its total raised with its latest funding round.

MacroFab, a Houston-based electronics manufacturing platform, has announced $42 million in new growth capital led by Foundry and joined by BMW i Ventures, as well as existing investors Edison Partners and ATX Venture Partners. The platform was first launched by Misha Govshteyn and Chris Church in 2015.

“Given MacroFab’s compelling solutions to electronics manufacturing challenges and Foundry’s successful history with parallel companies, our investment is a perfect fit," Foundry Partner Seth Levine says in a news release. "This is a unique opportunity to be part of next generation cloud manufacturing and we’re excited to be joining forces with Misha and his team."

MacroFab built a platform that manage electronics manufacturing and enables real-time supply chain and inventory data. The platform can help customers go from prototype to high-scale production with its network of more than 100 factories across the continent.

“Electronics manufacturing is moving toward resilience and flexibility to reduce supply chain disruptions. These are long term trends recognized by Foundry and BMW i Ventures, who joined this round as investors,” says Govshteyn, MacroFab’s CEO, in a news release. “We are in the earliest stages of repositioning the supply chain to be more localized and focused on what matters to customers most — the ability to deliver products on time, meet changing requirements, and achieve a more sustainable ecological footprint. MacroFab is fundamental to building this new operating model.”

The company has seen significant growth amid the evolution of global supply chain that's taken place over the past few years. According to the company, shipments were up 275 percent year-over-year. To keep up with growth, MacroFab doubled its workforce, per the release, and opened a new facility in Mexico.

“Most companies have felt the pain of inflexible and fragile supply chains," says Daniel Herscovici, partner at Edison Partners, a growth equity firm focused on technology-enabled and SaaS solutions. "MacroFab’s cloud manufacturing platform is transforming contract manufacturing, enabling ‘Made in North America, faster design iteration, and increased supply chain resiliency, among its benefits. Edison Partners shares the company’s vision for addressing this more than $100 billion global market."

Misha Govshteyn, CEO of MacroFab Misha Govshteyn is the founder and CEO of MacroFab. Photo courtesy of MacroFab

This week's roundup of Houston innovators includes Juliana Garaizar of Greentown Houston, Misha Govshteyn of MacroFab, and Kerri Smith of the Rice Alliance. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to two local innovators, as well as one honorary Houstonian, across industries — energy, manufacturing, and more — recently making headlines in Houston innovation.

Juliana Garaizar, head of Greentown Houston and vice president of Greentown Labs

Juliana Garaizar is transitioning her role at Greentown Houston. Courtesy photo

Juliana Garaizar has a new role within Greentown Labs. She's lead the local team as launch director, and now is taking a new role now that Greentown Houston has opened its doors. Garaizar recently discussed with InnovationMap why now is the perfect time for Greentown to premiere in Houston.

"I think that if Greentown had happened one year before or even one year later, it wouldn't be the right time. I really believe that our main partners are transitioning themselves — Shell, Chevron, and many others are announcing how they are transitioning," she says. "And now they look at Greentown as an execution partner more than anything. Before, it was a nice initiative for them to get involved in. Now, they are really thinking about us much more strategically." Click here to read more.

Misha Govshteyn, CEO of MacroFab

Misha Govshteyn joins the Houston Innovators Podcast to discuss the evolving electronics manufacturing industry. Photo courtesy of MacroFab

Electronics manufacturer and MacroFab, run by CEO Misha Govshteyn, much like the rest of the business world, was not immune to the effects of the pandemic. But as some business returned last summer, Govshteyn says MacroFab bounced back in a big way.

"In a lot of ways, the concepts we've been talking about actually crystalized during the pandemic. For a lot of people, it was theoretically that supply chain resiliency is important," Govshteyn says on this week's episode of the Houston Innovators Podcast. "Single sourcing from a country halfway around the world might not be the best solution. ... When you have all your eggs in one basket, sooner or later you're going to have a break in your supply chain. And we've seen nothing but breaks in supply chains for the last five years." Click here to read more.

Kerri Smith, interim executive director of the Rice Alliance Clean Energy Accelerator

A new clean energy accelerator has announced its first cohort. Photo via rice.edu

The Rice Alliance Clean Energy Accelerator, a 12-week program that will prepare startups to grow their business, connect them with strategic partners and mentors, launch pilots, and fundraise, has named its inaugural cohort.

"We were impressed with the quality, potential and range of clean energy solutions being commercialized by our applicant pool and took great care in assessing their potential as well as our ability to meet their identified needs," says Kerri Smith, the accelerator's interim executive director. "The selection process was very competitive. We had a difficult time paring down the applications but are looking forward to working with our first class of 12." Click here to read more.

Misha Govshteyn joins the Houston Innovators Podcast to discuss the evolving electronics manufacturing industry. Photo courtesy of MacroFab

Global electronics manufacturing is changing — and this Houston company is leading the way

HOUSTON INNOVATORS PODCAST EPISODE 87

When the pandemic hit, global supply chains across industries were affected, and major corporations and consumers alike continue to be affected — especially when it comes to manufacturing.

In March, General Motors had to shutdown production at three factories due to the global shortage of semiconductors, while gaming systems like PlayStation and Xbox are dealing with a chip shortage that will affect production into next year.

Houston-based MacroFab has a solution. The company has developed a software solution and digital platform to optimize electronics manufacturing by creating a network of factories across North America. The growing business, which was founded in 2013 by Chris Church, saw a setback at the beginning of the pandemic just like most industries. But, Misha Govshteyn, CEO of MacroFab, says the company finished last year on track.

"We really reignited our growth in the second half of 2020 just as the economy started to reopen," Govshteyn says on this week's episode of the Houston Innovators Podcast. "We had about 100 percent growth in the second half of the year, and that really led to our ability to close our most recent round."

That round — a $15 million series B — was led by New Jersey-based Edison Partners. ATX Venture Partners also participated, along with strategic investor Altium Limited, a leader in the electronics design software space. Govshteyn says that it's an important moment for MacroFab to prove out its solution to manufacturing.

"In a lot of ways, the concepts we've been talking about actually crystalized during the pandemic. For a lot of people, it was theoretically that supply chain resiliency is important," Govshteyn says. "Single sourcing from a country halfway around the world might not be the best solution. ... When you have all your eggs in one basket, sooner or later you're going to have a break in your supply chain. And we've seen nothing but breaks in supply chains for the last five years."

For years, global manufacturers have faced supply chain challenges with tariffs, and the pandemic and its accompanying shutdowns took these challenges to a whole new level.

"Supply chains haven't recovered — if anything, things have gotten worse. It's a perfect storm of customers realizing they have to rethink the way they source products," Govshteyn says.

One of the ways to bring the logistics of the process into the modern era. Some industries, like plastics manufacturing, are already doing this, Govshteyn says, but MacroFab has a huge opportunity within electronics.

"We think everything's going to look like a cloud service in the future. Everything is going to be software-driven, and API-addressable," Govshteyn says. "We're staking a claim to electronics manufacturing being one of those areas — and we're still the only company doing so."

Govshteyn shares more about the manufacturing business and the role Houston is playing on the episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes

MacroFab's latest $15 million round will help it expand and grow throughout North America. Photo via macrofab.com

Houston-based electronics manufacturing biz raises $15M in new funding

money moves

A Houston company that has optimized electronics manufacturing by setting up a digital platform connecting a network of factories across North America has raised its latest round of funding.

MacroFab closed a $15 million series B round led by New Jersey-based Edison Partners. ATX Venture Partners also participated, along with strategic investor Altium Limited, a leader in the electronics design software space.

The new funds will go toward keeping up with MacroFab's growth, specifically in expanding in North America and an increased investment in research and development, sales and marketing, and the opening of a new distribution center for international logistics this summer, according to a news release.

"MacroFab customers found themselves in a perfect storm last year, and went from being curious about cloud-enabled manufacturing to going all-in," says Misha Govshteyn, MacroFab CEO, in the release. "The turbulence started with the trade war and tariffs, and only accelerated with massive delays in delivering products from overseas and the ongoing microchip availability crisis.”

Govshteyn says the pandemic has affected traditional manufacturing processes. While some companies utilized manufacturing in China, international travel meant for impossible in-person troubleshooting. Digitization became increasingly optimal.

"Supply chain leaders are turning to MacroFab and our digital platform as a way to move faster," Govshteyn continues in the release. "If you're not as big as Apple, but want to build across multiple factories in parallel, our platform is the only way to do so without incurring immense costs".

MacroFab was founded in 2013 and has raised both seed and series A financing led by ATX Venture Partners and Techstars. Govshteyn and his co-founders — Chris Church, who serves as chief product officer, Chris Granberry, the company's COO — previously co-founded Alert Logic.

The trio of entrepreneurs reconvened to address an opportunity in a market that was home to an antiquated process within manufacturing. Lately, MacroFab's clients are looking to reduce waste.

"A typical electronics factory is only 60 percent utilized, according to New Venture Research, which is startlingly inefficient," Church says in the release. "A number of our customers focused on Environmental and Social Governance (ESG) issues see our ability to tap into this capacity as a step towards ecologically sustainable production."

The deal includes a new board member for MacroFab. Daniel Herscovici, partner at Edison Partners, will join MacroFab's board of directors

The company has "a proven track record of building successful SaaS and cloud infrastructure businesses together, and are now bringing supply chain innovation to the market at a time when global electronics manufacturing is facing disruption," Herscovici says in the release. "MacroFab is at the center of driving the digital transformation needed to unlock factory capacity, manufacturing agility and efficiency, and even new economic and labor markets for electronics makers across North America."

MacroFab's raise also included a new strategic partnership with Altium, one of the largest players in the electronics design space, per the release.

"Altium shares MacroFab's vision for digital transformation of manufacturing in the electronics industry," says Ted Pawela, chief ecosystem officer at Altium. "Our investment in, and partnership with MacroFab is a huge step forward in connecting design, supply chain, and manufacturing to accelerate innovation."

Here's what Houston startups won prizes at the inaugural Venture Houston conference. Photo via Getty Images

Inaugural Houston Venture startup pitch competition names big winners and doles out nearly $1M

taking home the W

Just a few months ago, Venture Houston 2021 was just an idea. Now, the two-day conference concluded with over 2,500 registrants and doled out nearly $1 million in cash and investment prizes to startups.

The idea was to bring together startups, investors, corporations, and anyone who cares to advance the Houston tech ecosystem, says Sandy Guitar, managing director at HX Venture Fund, at the closing event. The conference, which was put on by HXVF, the Houston Angel Network, the Rice Alliance, and Houston Exponential, wrapped up with the announcement of nine startups taking home investment or cash prizes.

In its first year, the Venture Houston conference attracted over 266 startup applications, and a group of Houston innovation leaders named 30 semifinalists that pitched on Thursday, February 4. On Friday, February 5, seven finalists pitched:

  • Koda Health
  • Spark Biomedical Inc
  • PATH EX, Inc.
  • Conversifi
  • CellChorus
  • MacroFab, Inc.
  • Mainline

The top three startups in the competition took home cash prizes — Macrofab won first place and $15,000 from Halliburton Labs, Spark Biomedical won second place and $10,000 from Softeq, and PathEx won third place and $5,000 from ChampionX.

  • Work & Mother won $250,000 from The Artemis Fund
  • MacroFab won $250,000 — $100,000 from Mercury Fund and $150,000 from Carnrite Ventures
  • Conversifi won $200,000 — $100,000 from Next Coast Ventures and $100,000 from Live Oak Venture Partners
  • Koda Health won $50,000 from Houston Angel Network
  • CellChorus won $50,000 from Texas Halo Fund
  • Nesh won $50,000 from Plug and Play
  • Cemvita Factory won $25,000 from baMa

Two previously announced prizes — $500,000 from Fitz Gate Ventures and $250,000 from Montrose Lane — were not given out.

The Venture Houston organizers are already looking forward to next year's program, but in the meantime Guitar had a parting call to action.

"Keep helping your fellow entrepreneur," she says, "that's really what Venture Houston 2021 is really about at the end of the day. The entrepreneur journey is a difficult one — often a lonely one — and sometimes one of hard knocks. Please keep finding entrepreneurs within your ecosystem. Let's help them with our advice, our capital, and our understanding."

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Pharma giant considers Houston for $1B manufacturing campus

in the works

Another pharmaceutical giant is considering Houston’s Generation Park for a manufacturing hub.

According to a recent filing with the Texas Jobs, Energy, Technology and Innovation (JETI) program, Bristol Myers Squibb Co. is considering the northeast Houston management district for a new $1 billion multi-modal pharmaceutical manufacturing campus.

If approved, the campus, known as Project Argonaut, could create 489 jobs in Texas by 2031. Jobs would include operations technicians, engineering roles, administrative and management roles, production specialists, maintenance support, and quality control/assurance. The company predicts annual average wages for these positions to be around $96,000, according to the filing.

The project currently includes the 600,000-square-foot facility, but according to the filing, Bristol Myers Squibb “envisions this site growing in scale and capability well beyond its opening configuration."

The Texas JETI program offers companies temporary school property tax limitations in exchange for major capital investment and job creation. E.R. Squibb & Sons LLC applied for a 10-year tax abatement agreement in the Sheldon Independent School District.

The agreement promises a $ 1 billion investment. Construction would begin in 2027 and wrap in 2029.

“The proposed project reflects [Bristol Myers Squibb Co.’s] enduring commitment to bringing innovative medicines to patients and ensuring the long-term supply reliability they depend on,” the filing says. “The proposed project is purpose-built to support and manufacture medicines spanning multiple therapeutic areas and modalities, positioning the site as a long-term launch and commercial campus for decades to come. These medicines will provide therapies to the [Bristol Myers Squibb Co.’s] patients located in markets both nationally and internationally.”

The Fortune 100 company is considering 16 other cities for the new manufacturing facility in the Central and Eastern markets in the U.S. According to the Houston Chronicle, Bristol Myers Squibb Co is still in the “evaluation process” for its potential manufacturing site.

Last fall, Eli Lilly and Co. selected Generation Park for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

Houston health tech co. lands NIH grant for AI cancer prediction tool

fresh funding

Houston-based CellChorus and Stanford Medicine were recently awarded a Phase I Small Business Innovation Research grant for the company's AI platform to test how certain cancer patients will respond to therapies.

The funding comes from the National Cancer Institute of the National Institutes of Health. According to a filing, the grant totaled just under $400,000.

CellChorus, which spun out from the University of Houston’s Technology Bridge, has developed TIMING (Time-lapse Imaging Microscopy In Nanowell Grids), which analyzes the behavior of thousands of individual immune cells over time and can identify early indicators of treatment success or failure.

The company will work with Stanford's Dr. David Miklos and Dr. Saurabh Dahiya, who have built the Bone Marrow Transplantation and Cell Therapy Biobank. The biobank manages and stores biological samples from patients treated at their clinic and in clinical trials.

"Predicting which patients will achieve durable responses after CAR-T therapy remains one of the most important challenges in the field,” Miklos said in a news release. “We aim to uncover functional cellular signatures that can guide treatment decisions and improve patient outcomes.”

The project will specifically profile cells from patients with relapsed/refractory large B-cell lymphoma (r/rLBCL). According to CellChorus, only about half of r/rLBCL patients who receive CAR-T therapy "achieve a durable, long-term remission." Others do not respond to therapy or experience relapse.

“The sooner we know whether a cancer therapy is working, the better. To maximize patient benefit, we need technology that can provide a robust and early prediction of response to therapy. The technology needs to be scalable, cost-efficient, and capable of rapid turnaround times,” Rebecca Berdeaux, chief scientific officer of CellChorus, added in the release. “We are excited to work with Drs. David Miklos and Saurabh Dahiya and their colleagues on this very important project.”

CellChorus has previously received SBIR grants from federal agencies, including a $2.5 million award in 2024 from its National Center for Advancing Translational Sciences (NCATS) and a $2.3 million SBIR Fast-Track award from the National Institute of General Medical Sciences in 2023.

Houston museum showcases America's founding documents in rare exhibit

Experience History

As the United States prepares to celebrate its 250th birthday, Houstonians have a chance to see rare documents from the founding of the nation. Freedom Plane National Tour: Documents That Forged a Nation, presented by the National Archives Foundation, will be on display at the Houston Museum of Natural Science through Monday, May 25.

The collection includes a rare engraving of the original Declaration of Independence; official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton; a draft of the Bill of Rights; the Treaty of Paris, the documented that recognized America's independence from Great Britain; and the tally of votes approving the Constitution.

The National Archives specifically chose Houston as one of only eight cities in the country to host the exhibit as a means to help the documents reach a wider audience outside of the main hub of semiquincentennial events in New England and the Washington, D.C. area.

"One of the things we decided when we put the tour together because we wanted to be off the East Coast," said Patrick Madden, CEO of the National Archives Foundation, who was onsite for the exhibit's opening in Houston. "There's a lot of 250th celebration stuff happening in the original 13 colonies. How do we get it to major markets where larger numbers of people can see it? So in the case of Houston, obviously, [is a] major market in this part of the country, but also we've partnered with the museum twice before with National Archives exhibits, so we knew that they would be up to the task of handling the exhibit and the crowds."

The star of the collection is a rare engraving of the original Declaration of Independence. Secretary of State and future president John Quincy Adams commissioned 200 exact replicas of the document from engraver William J. Stone in 1823. Less than 50 now remain. Madden joyfully pointed out that there are errors in this document, a potent reminder that the men who forged a nation made mistakes.

"There's a couple of typos in it where they had to make corrections," said Madden. "So even the founders, you know, they're all human. That resonates because here these people are making this move against the most powerful nation in the world and putting their lives on the line for a country based on ideas."

Other impressive parts of the collection include official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton, as well as one of the drafts of the Bill of Rights. Many states would not ratify the Constitution until certain rights were included in the document, leading to Washington going on a national tour assuring state leaders enshrining protections was first on the list. The draft copy on display specifically shows the First Amendment in progress.

Houston is the fourth stop on the exhibition's tour, which will take the documents to Denver, Miami, Dearborn, and Seattle through the summer. Freedom Plane is just one part of a larger patriotic celebration at the HMNS, which includes a film series celebrating American science and culture and general Americana decoration throughout the main hall.

Admission to Freedom Plane is free to the public, but separate from general admission to the museum. Space is limited, and passes are available on a first-come, first-serve basis. Non-members should expect long waits or the possibility that the day's passes are sold out. Only museum members can reserve passes for specific times. Flash photography is prohibited due to the fragile nature of the documents.

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This article originally appeared on CultureMap.com.