From closing a million-dollar raise to being tapped by Google to serve on a council, Houston entrepreneurs have been busy. Courtesy of Security Gate

Wrapping up March, there's been a lot of innovator and startup news that's slipped through the cracks. From funds closing and incubator applications opening, here's all the news bits you need to know.

SecurityGate closes $1 million fund

Photo via securitygate.io

Houston-based SecurityGate closed its $1 million seed round on March 22. The lead investor was a private investment group in Houston. The startup, a B-to-B, software-as-a-service cybersecurity company, will use the funds to further refine its business and grow its team.

"We're excited our investment team understands the need for digital transformation in the critical infrastructure security space," CEO and co-founder, Ted Gutierrez says.

In February, SecurityGate traveled to Charlotte, North Carolina, to accept the Game Changers award. Gutierrez said being able to bring home that award really spurred the last leg of the raise.

Impact Hub Houston launches with fundraising campaign

Photo via LinkedIn

Houston's Impact Hub, a nonprofit organization focused on impacting change within the world through startups and technologies, has officially launched. The organization also launched its fundraising campaign called 321 Impact.

Led by Grace Rodriguez, Impact Hub Houston will set up shop in a few "pop-up" locations to truly serve all of the city. The first location will soon be announced, Rodriguez writes online.

Impact Hub Houston also announced a few other projects the organization has launched or is working on:

MassChallenge Texas will open Houston application at kick-off event

Photo via greenstreetdowntown.com

MassChallenge Texas announced its first Houston cohort in January, indicating that applications will open sometime in April. Last week, the zero-equity incubator program revealed that applications will open following an April 10th launch party event. The networking event will be at the Four Seasons in downtown Houston and will take place from 6 to 9 pm. Guests can RSVP here, and startups can begin the application process at masschallenge.org/apply to start their application. The application deadline is May 8, 2019 at noon.

Google taps Houston innovator for AI-focused council

Dyan Gibbons

Courtesy of Alice

Google has selected Houston innovator and founder of Trumbull Unmanned, Dyan Gibbens, as a member of its inaugural Advanced Technology Executive Advisory Council focused on AI. The council will meet with Google's executive leadership quarterly throughout 2019, beginning in April. Kent Walker, senior vice president of Global Affairs at Google, introduced Gibbens, and the fellow council members, in a blog post.

"We hope this effort will inform both our own work and the broader technology sector," writes Walker in the post. "In addition to encouraging members to share generalizable learnings in their ongoing activities, we plan to publish a report summarizing the discussions. Council members represent their individual perspectives, and do not speak for their institutions."

Houston to host nationwide pitch competition finals

Photo via celebrasianconference.com

The country's largest Asian organization is concluding its pitch competition in Houston. The contest, called What's Your Pitch: Innovations Meets the Market, is put on by the United States Pan Asian Chamber of Commerce. Chaired by Diane Yoo, former director of the Rice Angel Network, the semifinal and final rounds will take place in Houston on June 4 and 5, respectively. $100,000 work of cash and prizes is on the line. For more info on the contest, click here.

FutureSight AR selected as the only Texas startup for an international program

future sight AR

Courtesy of Future Sight AR

Houston-based Future Sight AR was selected for Magic Leap's Independent Creators Program in the productivity category and was awarded a grant to continue development. The program, which had over 6,500 applicants, will take place through March and some of April. FutureSight AR, which uses artificial reality to make oil and gas construction workers more productive, is the only startup represented from Texas in the program, says co-founder of the company, Lori-Lee Emshey.

Lyft introduces new programs and opportunities in Houston

Courtesy of Lyft

Lyft will bring or expand three driver-focused programs to the Houston market, the company announced this week.

  • Drivers can opt into Lyft Direct, a bank account with no fees that links to a debit card. Rather than cashing their check from Lyft, drivers can instantly access earnings and even receive points for cash back on specific purchases.
  • Lyft will open a Vehicle Service Center, which is a new and improved version of Lyft Hubs. The idea is to have mechanics work on the vehicles of Lyft drivers at cost, rather than the drivers having to pay full-price for their repairs. Also new to the program is the opportunity to provide mobile repair services for drivers on the go.
  • Lyft announced that Houston will have more locations of the Express Drive program, where Lyft drivers can use a rental car and receive subsidized earnings.

Blockchain entrepreneur profiled by Rice University publication

Courtesy of Topl

Houston-based Topl's co-founder, Kim Raath, was featured in a piece for Rice University as a part of the school's Spotlights on Diversity in Engineering. Her company, Topl, uses blockchain technology to connect the dots on industries — from food to oil and gas. To read the feature of how Raath went from backpacking through developing countries to startup founder, click here.

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Short stories will be a regular roundup on InnovationMap. If your company recently closed on a round, received recognition, or has any news, please email Natalie Harms at natalie@innovationmap.com with the information.

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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”