Self-driving delivery company with Houston pilots gets historic government approval for new model

hit the road

Nuro is now able to roll out its new model of self-driving vehicles in Houston thanks to a recent announcement from the government. Photo courtesy of Nuro

A California-based tech company has got the green light today to move forward a new line of autonomous vehicles that will soon hit Houston streets.

Nuro, which has a few self-driving delivery pilot programs across Houston, has been granted its exemption petition from the United States Department of Transportation's National Highway Traffic Safety Administration. This move is a first for DOT, and it allows Nuro to roll out its vehicles on public roads without the features of traditional, passenger-carrying vehicles — like side mirrors or windshields, for instance.

"Since this is a low-speed self-driving delivery vehicle, certain features that the Department traditionally required – such as mirrors and windshield for vehicles carrying drivers – no longer make sense," says U.S. Secretary of Transportation Elaine L. Chao in a news release.

Now, with this permission, Nuro has unveiled its newest model — the R2. The new model is more narrow than the R1, and has 65 percent more climate-controlled space for its food deliveries. The vehicle also has new safety features, like 360-degree vision using lidar, radar, and cameras and even has a pedestrian-protecting feature that enables the car to collapse on impact.

Image courtesy of Nuro

"We founded Nuro on the belief that we could reimagine, design, and develop an autonomous vehicle that would make the world a safer place," says Nuro co-founder and president, Dave Ferguson, in a release. "Our second-generation vehicle will advance our goal of transforming local commerce, and we are gratified that the Department of Transportation, under Secretary Chao's leadership, is promoting public safety and providing regulatory certainty for the self-driving industry."

The R2 models are being assembled in the U.S. with Nuro's partner, Roush Enterprises, which is based in Michigan. Per the NHTSA announcement, Nuro can deploy up to 5,000 R2 vehicles during the two-year exemption period. According to the DOT release, the organization will be monitoring Nuro's work throughout those two years.

"NHTSA is dedicated to facilitating the safe testing and deployment of advanced vehicle technologies, including innovative vehicle designs, which hold great promise for future safety improvements," says NHTSA Acting Administrator James Owens in the release. "As always, we will not hesitate to use defect authority to protect public safety as necessary."

Nuro currently has three pilot programs — all of which were announced last year. The company is working with Domino's, Kroger, and Walmart on food and grocery deliveries in six Houston ZIP codes. Since entering the Houston market, Nuro has been using its fleet of self-driving Prius vehicles to research and map the city's roads.

With this permission granted from DOT, Nuro can start making deliveries using its R2 fleet with its three retail and restaurant partners.

"Today's decision shows that 'exemption' can mean more safety," says Ferguson. "Our world-class team solved countless novel problems to create this design, and, after extensive modeling, research, and testing, created a vehicle unlike any other on the road today."

Photo courtesy of Nuro

Kroger's self-driving cars are coming to Houston. Courtesy of Kroger

Kroger's autonomous car fleet heads to Houston for a new grocery delivery service

Look ma, no hands

Hold on to your hats, Houston. Autonomous cars are hitting the streets this spring as Kroger rolls out its fleet of self-driving, grocery-delivery cars.

Two Houston Kroger locations will provide the service to four ZIP codes — 10306 South Post Oak Road, servicing 77401 and 77096, and 5150 Buffalo Speedway, servicing 77005 and 77025.

Kroger, along with California-based robotics company, Nuro, has been operating self-driving cars delivering groceries in Scottsdale. Arizona since August. According to the release, the service has delivered thousands of orders in the self-driving vehicles.

"We've seen first-hand in Arizona how enthusiastic customers are about getting their Kroger groceries delivered by a Nuro self-driving vehicle," says Nuro co-founder, Dave Ferguson, in a release. "Texas has been a leader in encouraging self-driving innovation, and we're excited to help deliver that future for Houston — a dynamic, diverse, and welcoming metropolitan city that we're excited to soon explore and serve with this autonomous delivery service."

The service costs a flat fee of $5.95, and users can order in the app or online for same-day or next-day delivery, seven days a week. The program will launch using Toyota Prius vehicles. Currently, the exact start date of the service hasn't been provided.

"Our Arizona pilot program confirmed the flexibility and benefits provided by autonomous vehicles and how much customers are open to more innovative solutions," says Yael Cosset, Kroger's chief digital officer, in a release. "It's always been our shared vision to scale this initiative to new markets, using world-changing technology to enable a new type of delivery service for our customers. We operate 102 stores in Houston—an energetic market that embraces digital and technology advancement. The launch is one more way we are committed to sustainably providing our customers with anything, anytime, and anywhere, the way they want it."

In January, the Texas Department of Transportation created the Connected and Autonomous Vehicle Task Force to focus on being a comprehensive resource for information on all Texas CAV projects, investments, and initiatives.

"With our world-class universities, top-notch workforce and startup culture, Texas is a national leader in the development of new technologies," says Gov. Greg Abbott in the release. "As transportation technology advances, the CAV Task Force will ensure that the Lone Star State remains at the forefront of innovation."

Courtesy of Kroger

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”
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