Houston's innovation leaders weigh in on community's growth, progress

Houston innovation awards

Get to know the Houston innovation community's top ecosystem builders. Photos courtesy

This year's finalists in the Ecosystem Builder category for the Houston Innovation Awards have a lot to say about the city's innovation community — and they are the right ones to say it.

Selected as finalists for the newly created category, each of the five finalists are leaders for the Houston innovation ecosystem. They were each asked some questions about the development of the Houston tech and startup community. Here's what they had to say.

InnovationMap: What is your favorite part of Houston's innovation ecosystem? How have you helped contribute to that aspect of the community?

Jan E. Odegard, executive director of the Ion: Can do attitude and willingness to make big bets that can solve hard problems with global societal impact. Creating and supporting a place where this can happen is critical to the success, a place where we create the necessary density for collisions and that will sprue the next ideas.

Jason Ethier, co-founder of Lambda Catalyzer and host of the Energy Tech Startups podcast: Perhaps small, but the Ion District in the small part we have to play in it. Being able to be in a place where you can cross paths with active investors, innovators and partners. This is the hub we hoped to build over the last few years. That connective tissue may be small and focused compared to other ecosystems, but it is very strong here.

Joey Sanchez, founder of Cup of Joey and senior director of ecosystems at the Ion: My favorite part of the Houston Innovation Ecosystem is the progress and potential. We have gone from talking about how to build a Houston ecosystem to now exploring our collective potential. The conversations are now tactical actions to scale our efforts.

Kendrick Alridge, senior manager of community at Greentown Labs: My favorite part of the ecosystem is the Cup of Joey gathering. It's a great opportunity to run into or catch up with people looking to get involved in the ecosystem or looking for support. It's a great networking opportunity.

Wade Pinder, founder of Product Houston: I love seeing how the community has really connected this past year specifically. We've gathered momentum and have a "gravity well" of community leaders feeding value to one another.

IM: What are the strengths of the Houston innovation ecosystem?

Odegard: Access to (engineering) talent, capabilities, and global connectivity that are not afraid of getting her hands dirty to build and scale.

Ethier: The diversity of the founders and the intrinsic diversity of the Houston ecosystem. There are few native Houstonians, and most of the fantastic founders we meet are from somewhere else. The energy industry brings the best of the best from around the world and they inject Houston with unique excellence.

Sanchez: We are a resource right environment. We have a plethora of talent and capital. With the economy the size of Belgium, we have access to industries and talent unlike any other city. Also the convergence of energy, medical and aerospace is one of a kind. Each industry is transforming and providing a ripe opportunity for innovation.

Alridge: The growing number of startup development organizations (SDOs), incubators and accelerators, makerspaces, co-working spaces, non-profits, and academic institutions that is available is a strength, because their are plenty of places to get support and your ideas off the ground.

Pinder: We do hard things here because the ARE hard! 1) Life and death situations en masse, 2) infrastructure at scale 3) Boldly going where no one has gone before! That's what we've done here. That's what we stand to innovate on! If it's a hard problem, Houston gets it done!

IM: What are the weaknesses of the Houston innovation ecosystem? Are you helping to make improvements to these weaker aspects of the community and, if so, how?

Odegard: Access to more risk capital.

Ethier: We need a skill set on scaling businesses. This is something the valley does exceptionally well. When there is product market fit, the startup ecosystem knows how to scale teams from 20-200 and do so repeatedly. Houston knows how to do big energy projects; from sput to TD, there is a skill set here around complexity...but how that applies to scaling businesses its unclear we have what it takes. This is why its imperative we bring in mature startups from around the country and try to transfer knowledge from the energy industry into the startup space. Building an acceleration program like Lambda is a step in solving this problem.

Sanchez: Density is our biggest challenge. The geographic sprawl of our region is vast. Serendipitous meetings are a challenging. The Ion has created a central place where our ecosystem can come together. Every Friday we meet for Cup of Joey and now we host a Cup of Joey in The Woodlands, Space Center Houston, Sugar Land and The Cannon West. Creating eight Cup of Joey meetups each month. The most exciting element of Cup of Joey is coming in an online platform for connection.

Alridge: We need a robust cadre of startup specialists, serial entrepreneurs who have successfully started companies. Especially in business and STEM fields, is needed in the innovation system. Higher education in providing talent is important, I'm doing my part by organizing opportunities for students to work with our startups which can directly and indirectly contribute to the workforce and the grown startup community.

Pinder: We're changing this... but we still have a ways to go with the "I'm good... what do I need to show up for?" thinking. It's not for lack of wanting to show up... traffic makes it tougher to show up most of the time.

IM: What do you wish more people knew about the Houston startup community?

Odegard: That Houston IS a tech hub addressing some of the biggest societal challenges we are face today, such as: power (security), healthcare (affordable and accessible), sustainability (clean and green), and equitable access to economic opportunities.

Ethier: How climate focused everyone is, from the founders, to the SMEs, industry and SMEs. Houston (and energy companies) know how to manage what's measured and now that we have targets around decarbonization, we are going to get it done.

Sanchez: I wish the world knew more about Houston and our Houston startup community. I believe that our foundation is strong and we are ready for scale. 2026 to 2036 will be a decade of massive growth for Houston and our ecosystem.

Alridge: We are more than oil and gas and health care.

Pinder: We've got the solutions to some huge problems sitting right here in Houston.

Click here to secure your tickets to the November 8 event where we announce the winner of this exciting new category.

From Your Site Articles
Capital Factory will have a branded area in The Cannon when it opens its new facility. Courtesy of The Cannon

Capital Factory hires two Houston-based employees to grow its local presence

Onboarding

A major Texas innovation player with roots in Austin has now staffed its recently announced Houston outpost in partnership with The Cannon Houston. Capital Factory hired two Houstonians to help provide resources for its growing Houston-based portfolio companies.

Kendrick Alridge has been hired as mentor coordinator, and Brittany Barreto, who founded Pheramor and WeHaveChemistry, has been named the venture associate. Aldridge will focus on growing and cultivating relationships with Houston mentors, and Barreto is dedicated to reaching out to Houston startups to gauge their potential for Capital Factory participation.

Hiring these Houstonians and having these new boots on the ground is a key factor for Capital Factory as it grows its Houston presence, says Gordon Daugherty, president at Capital Factory.

"It's important for us to think Texas, but act local," Daugherty says. "What that means is we can't just assume that the way we do things and the things that made us successful in Austin will directly translate to Houston. Houston is a different market. That's one of the things we learned from Dallas."

Acting locally entails listening and learning to what the community wants and engaging with local organizations to contribute value to the market.

"We don't know how or in which ways, but we know Houston will be different from Dallas and Austin," Daugherty says. "In this way, we are advantaged by our two employees being from the Houston area. They're our eyes and ears, for one, but they are also the voice of Houston to us along with other ecosystem players."

While local resources and personnel are both new for Capital Factory, the organization already has over 20 portfolio companies that are based in the Houston area. Now, these companies will have new resources close to home and can also act as Capital Factory representatives in the community, Daugherty says.

One of the biggest benefits Capital Factory is bringing into town is investment opportunities. Daugherty says that he predicts that Capital Factory, which tends to invest many small-sum deals, will quickly become the most active early stage investor in Houston. The organization has already made a few investments in Houston companies — and this isn't even counting the dollars invested by the investment partners.

"Our mission, as it pertains to Houston, is to help the best Houston startups get funded. We will tap into our network of investors across the state and country to try to find the best matches."

If Houston can take any indication from Capital Factory's Dallas location, which opened earlier this year, Capital Factory will be making a big impact on Houston startups.

"In 2018, 25 percent of the startups we onboarded into the accelerator were from outside of Austin," Daugherty tells InnovationMap. "The first half of this year, a third or more have come from Dallas alone. And I expect the same from Houston. Next year, easily more than half of our new accelerator companies will be outside of Austin."

Capital Factory will have branded space in The Cannon when it opens its new facility later this month.

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Microsoft partners with Rice University's OpenStax on AI teaching tool

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Rice University’s OpenStax and Microsoft are partnering to integrate the nonprofit’s content with the tech giant’s AI innovation, known as Learning Zone.

“At OpenStax, our mission is to make an amazing education accessible to all,” Richard G. Baraniuk, founder and director of OpenStax, said in a news release. “That’s why we’re excited to integrate our trustworthy, peer-reviewed content with Microsoft’s AI technology through the Microsoft Learning Zone. Together, we aim to help more instructors and their students access engaging, effective learning experiences in new and dynamic ways. We also share a strong commitment to the thoughtful and responsible application of AI to better ensure all learners can succeed.”

OpenStax is a provider of affordable instructional technologies and is also one of the world’s largest publishers of open educational resources (OER).

Microsoft Learning Zone promises to provide educators and students with “responsible AI technology and peer-reviewed educational content to support learning” on Microsoft Copilot+ PCs. Microsoft Learning Zone works by utilizing on-device AI to generate interactive lessons for students, and its integration with OpenStax content means educators can rely on OpenStax’s digital library of 80 openly licensed titles.

The goal is for educators to create effective and engaging learning experiences safely, thereby bypassing the need to source and vet content independently. Included is a library of ready-to-use lessons, opportunity for immediate feedback and differentiated learning. Educators will maintain control of instructional content and pedagogical strategies and will be able to update or edit lessons or activities prior to sharing them with students.

Other tools included in the Microsoft Learning Zone are additional languages, reading coaching, public speaking help, math and reading progress, and a partnership with the online quiz platform Kahoot!

OpenStax resources have been reported as used across 153 countries, and this current collaboration combines the power and potential of responsible AI usage in education with content that has been utilized by 13,569 K-12 schools and 71 percent of U.S. colleges and universities, according to Rice.

“Through our partnership with OpenStax, we’re combining the power of on-device AI in Copilot+ PCs with OpenStax’s trusted and diverse peer-reviewed content to help educators quickly create high-quality, personalized, engaging lessons,” Deirdre Quarnstrom, vice president of Microsoft Education, added in the news release. “We’re excited about how this collaboration will empower classrooms globally.”

Houston ranks among the 15 best cities in America for 2025

Ranking It

A new national report ranking the best cities in America has declared Houston is the 13th best U.S. city in 2025.

The annual "America's Best Cities" report from Resonance Consultancy, a Canada-based real estate and tourism marketing firm, ranks the relative qualities of livability, cultural "lovability," and economic prosperity in America's principal cities with metropolitan populations of 500,000 or more.

These top 100 cities "brilliantly weave local culture with economic prospects, aligning with global and domestic travel trends to create premier experiences for both residents and travelers."

Houston's new placement is three spots lower than its triumphant No. 10 rank in 2024. Though it no longer holds a prized top-10 spot, the report hails Houston as a "coveted hometown for the best and brightest on earth."

Among Houston's other shining attributes are its booming population growth – which has now grown to a staggering 7.51 million people – plus its competitive real estate market and a vibrant hospitality and culinary scene. Additionally, Houston earned a well-deserved No. 4 rank in the report's "restaurants" subcategory.

"A 221-room Home2 Suites/Tru by Hilton debuted near Toyota Center in March, while Marriott’s newly renovated Residence Inn NASA/Clear Lake keeps surging visitors happy," the report said. "West Houston’s Greenside will convert 35,000 square feet of warehouses into a park-laced retail hub by 2026, while America’s inaugural Ismaili Center, rising along Allen Parkway, remains on schedule for later this year, adding yet another cultural jewel to H-Town’s festival-fueled mosaic."

The report additionally puts a large focus on Houston's innovative energy sector and its numerous large companies that boost the local economy and create thousands of jobs. Several of these Houston-based companies are some of the best places to work, according to U.S. News and World Report.

One such company that was specifically praised in the report was the HyVelocity Hub, which aims to "ensure economic resilience and long-lasting, domestic energy production" along the Gulf Coast.

"The HyVelocity Hydrogen Hub just locked in up to $1.2 billion from the U.S. DOE, targeting 45,000 jobs and slicing 7.7 million tons of CO₂ a year," the report said.

Elsewhere in Texas

Dallas (No. 14) and Austin (No. 15) ranked right behind Houston in the top 20, while San Antonio sank into the No. 41 spot after previously ranking 32nd last year. El Paso also fell from No. 83 in 2024 to No. 100 this year.

Jason McGrath, the executive vice president and head of U.S. Corporate Reputation at Ipsos, said in the report that American cities are proving their resiliency as they are faced with "climate issues, increasing infrastructural demands, and shifting geopolitical landscapes affecting international relations and travel."

"Despite these hurdles, cities are creatively reinventing themselves to shine as examples of cultural vibrancy and innovation, keeping their competitive edge both locally and globally," McGrath said. "Our report shows that the allure of American cities remains strong, thanks to their rich diversity and vast attractions — from natural wonders to buzzing cultural hubs."

The top 10 best cities in America in 2025 are:

  • No. 1 – New York City, New York
  • No. 2 – Los Angeles, California
  • No. 3 – Chicago, Illinois
  • No. 4 – San Francisco, California
  • No. 5 – Seattle, Washington
  • No. 6 – Miami, Florida
  • No. 7 – Boston, Massachusetts
  • No. 8 – Washington, D.C.
  • No. 9 – Las Vegas, Nevada
  • No. 10 – San Diego, California
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This article originally appeared on CultureMap.com.

Houston biosciences company opens new sequencing center for drug development

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Houston-based Avance Biosciences has launched the Next-Generation Sequencing Center of Excellence, designed to enhance the company’s sequencing capabilities for drug development. Specifically, the facility at the company’s main campus in Northwest Houston will pursue breakthroughs in biologics, cell therapy and gene therapy.

In the drug industry, sequencing refers to studying nucleotides in DNA and RNA molecules. Nucleotides are the building blocks of DNA and RNA.

“This is a major milestone for Avance Biosciences as we continue to support the evolving needs of biologics and cell and gene therapy developers,” Xuening “James” Huang, co-founder, CEO and chief technology officer of Avance, said in a news release. “By consolidating state-of-the-art sequencing platforms and scientific talent, we’ve created a highly capable organization ready to solve complex genomic challenges with precision and compliance.”

In 2013, Avance rolled out next-generation sequencing (NGS) that complies with federal guidelines. Since then, Avance “has remained at the forefront of regulated sequencing services,” the company said. “The launch of the (new center) strengthens the company’s ability to deliver accurate, reproducible, and regulatory-aligned sequencing data across a wide array of therapeutic modalities.”

Cal Froberg, senior vice president of sales and marketing at Avance, said pharmaceutical and biotech clients trust the company’s technical capabilities and regulatory compliance.

“With the ever-changing global landscape and increasing scrutiny around international sample shipments, conducting advanced, cost-effective NGS testing domestically is now more feasible than ever,” Froberg said. “Our clients have confidence that their samples will remain in the U.S.”

Avance, founded in 2010, plans to hold an open house at the new facility in September to showcase its capabilities, technology, talent, and services. The company’s services include sequencing, molecular biology, cell-based testing, and bioanalytical testing.
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