Houston's innovation leaders weigh in on community's growth, progress

Houston innovation awards

Get to know the Houston innovation community's top ecosystem builders. Photos courtesy

This year's finalists in the Ecosystem Builder category for the Houston Innovation Awards have a lot to say about the city's innovation community — and they are the right ones to say it.

Selected as finalists for the newly created category, each of the five finalists are leaders for the Houston innovation ecosystem. They were each asked some questions about the development of the Houston tech and startup community. Here's what they had to say.

InnovationMap: What is your favorite part of Houston's innovation ecosystem? How have you helped contribute to that aspect of the community?

Jan E. Odegard, executive director of the Ion: Can do attitude and willingness to make big bets that can solve hard problems with global societal impact. Creating and supporting a place where this can happen is critical to the success, a place where we create the necessary density for collisions and that will sprue the next ideas.

Jason Ethier, co-founder of Lambda Catalyzer and host of the Energy Tech Startups podcast: Perhaps small, but the Ion District in the small part we have to play in it. Being able to be in a place where you can cross paths with active investors, innovators and partners. This is the hub we hoped to build over the last few years. That connective tissue may be small and focused compared to other ecosystems, but it is very strong here.

Joey Sanchez, founder of Cup of Joey and senior director of ecosystems at the Ion: My favorite part of the Houston Innovation Ecosystem is the progress and potential. We have gone from talking about how to build a Houston ecosystem to now exploring our collective potential. The conversations are now tactical actions to scale our efforts.

Kendrick Alridge, senior manager of community at Greentown Labs: My favorite part of the ecosystem is the Cup of Joey gathering. It's a great opportunity to run into or catch up with people looking to get involved in the ecosystem or looking for support. It's a great networking opportunity.

Wade Pinder, founder of Product Houston: I love seeing how the community has really connected this past year specifically. We've gathered momentum and have a "gravity well" of community leaders feeding value to one another.

IM: What are the strengths of the Houston innovation ecosystem?

Odegard: Access to (engineering) talent, capabilities, and global connectivity that are not afraid of getting her hands dirty to build and scale.

Ethier: The diversity of the founders and the intrinsic diversity of the Houston ecosystem. There are few native Houstonians, and most of the fantastic founders we meet are from somewhere else. The energy industry brings the best of the best from around the world and they inject Houston with unique excellence.

Sanchez: We are a resource right environment. We have a plethora of talent and capital. With the economy the size of Belgium, we have access to industries and talent unlike any other city. Also the convergence of energy, medical and aerospace is one of a kind. Each industry is transforming and providing a ripe opportunity for innovation.

Alridge: The growing number of startup development organizations (SDOs), incubators and accelerators, makerspaces, co-working spaces, non-profits, and academic institutions that is available is a strength, because their are plenty of places to get support and your ideas off the ground.

Pinder: We do hard things here because the ARE hard! 1) Life and death situations en masse, 2) infrastructure at scale 3) Boldly going where no one has gone before! That's what we've done here. That's what we stand to innovate on! If it's a hard problem, Houston gets it done!

IM: What are the weaknesses of the Houston innovation ecosystem? Are you helping to make improvements to these weaker aspects of the community and, if so, how?

Odegard: Access to more risk capital.

Ethier: We need a skill set on scaling businesses. This is something the valley does exceptionally well. When there is product market fit, the startup ecosystem knows how to scale teams from 20-200 and do so repeatedly. Houston knows how to do big energy projects; from sput to TD, there is a skill set here around complexity...but how that applies to scaling businesses its unclear we have what it takes. This is why its imperative we bring in mature startups from around the country and try to transfer knowledge from the energy industry into the startup space. Building an acceleration program like Lambda is a step in solving this problem.

Sanchez: Density is our biggest challenge. The geographic sprawl of our region is vast. Serendipitous meetings are a challenging. The Ion has created a central place where our ecosystem can come together. Every Friday we meet for Cup of Joey and now we host a Cup of Joey in The Woodlands, Space Center Houston, Sugar Land and The Cannon West. Creating eight Cup of Joey meetups each month. The most exciting element of Cup of Joey is coming in an online platform for connection.

Alridge: We need a robust cadre of startup specialists, serial entrepreneurs who have successfully started companies. Especially in business and STEM fields, is needed in the innovation system. Higher education in providing talent is important, I'm doing my part by organizing opportunities for students to work with our startups which can directly and indirectly contribute to the workforce and the grown startup community.

Pinder: We're changing this... but we still have a ways to go with the "I'm good... what do I need to show up for?" thinking. It's not for lack of wanting to show up... traffic makes it tougher to show up most of the time.

IM: What do you wish more people knew about the Houston startup community?

Odegard: That Houston IS a tech hub addressing some of the biggest societal challenges we are face today, such as: power (security), healthcare (affordable and accessible), sustainability (clean and green), and equitable access to economic opportunities.

Ethier: How climate focused everyone is, from the founders, to the SMEs, industry and SMEs. Houston (and energy companies) know how to manage what's measured and now that we have targets around decarbonization, we are going to get it done.

Sanchez: I wish the world knew more about Houston and our Houston startup community. I believe that our foundation is strong and we are ready for scale. 2026 to 2036 will be a decade of massive growth for Houston and our ecosystem.

Alridge: We are more than oil and gas and health care.

Pinder: We've got the solutions to some huge problems sitting right here in Houston.

Click here to secure your tickets to the November 8 event where we announce the winner of this exciting new category.

From Your Site Articles
Capital Factory will have a branded area in The Cannon when it opens its new facility. Courtesy of The Cannon

Capital Factory hires two Houston-based employees to grow its local presence

Onboarding

A major Texas innovation player with roots in Austin has now staffed its recently announced Houston outpost in partnership with The Cannon Houston. Capital Factory hired two Houstonians to help provide resources for its growing Houston-based portfolio companies.

Kendrick Alridge has been hired as mentor coordinator, and Brittany Barreto, who founded Pheramor and WeHaveChemistry, has been named the venture associate. Aldridge will focus on growing and cultivating relationships with Houston mentors, and Barreto is dedicated to reaching out to Houston startups to gauge their potential for Capital Factory participation.

Hiring these Houstonians and having these new boots on the ground is a key factor for Capital Factory as it grows its Houston presence, says Gordon Daugherty, president at Capital Factory.

"It's important for us to think Texas, but act local," Daugherty says. "What that means is we can't just assume that the way we do things and the things that made us successful in Austin will directly translate to Houston. Houston is a different market. That's one of the things we learned from Dallas."

Acting locally entails listening and learning to what the community wants and engaging with local organizations to contribute value to the market.

"We don't know how or in which ways, but we know Houston will be different from Dallas and Austin," Daugherty says. "In this way, we are advantaged by our two employees being from the Houston area. They're our eyes and ears, for one, but they are also the voice of Houston to us along with other ecosystem players."

While local resources and personnel are both new for Capital Factory, the organization already has over 20 portfolio companies that are based in the Houston area. Now, these companies will have new resources close to home and can also act as Capital Factory representatives in the community, Daugherty says.

One of the biggest benefits Capital Factory is bringing into town is investment opportunities. Daugherty says that he predicts that Capital Factory, which tends to invest many small-sum deals, will quickly become the most active early stage investor in Houston. The organization has already made a few investments in Houston companies — and this isn't even counting the dollars invested by the investment partners.

"Our mission, as it pertains to Houston, is to help the best Houston startups get funded. We will tap into our network of investors across the state and country to try to find the best matches."

If Houston can take any indication from Capital Factory's Dallas location, which opened earlier this year, Capital Factory will be making a big impact on Houston startups.

"In 2018, 25 percent of the startups we onboarded into the accelerator were from outside of Austin," Daugherty tells InnovationMap. "The first half of this year, a third or more have come from Dallas alone. And I expect the same from Houston. Next year, easily more than half of our new accelerator companies will be outside of Austin."

Capital Factory will have branded space in The Cannon when it opens its new facility later this month.

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Rice, Houston Methodist award $90K for cancer research projects

seed grants

Rice University’s Synthesis X Center, in partnership with the Houston Methodist Neal Cancer Center, announced earlier this month the organizations would award $90,000 in seed grant funding to two projects that could help fight cancer. One would ease the pain of chemotherapy, while the other could change the way the progression of leukemia is tracked.

“We’re excited to be collaborating with the Neal Cancer Center to support collaborative, novel and interdisciplinary proposals to improve cancer care and outcomes,” Han Xiao, Rice professor of chemistry and the director of the SynthX Center, said in a news release. “Together, we can achieve translational excellence.”

The projects

Chemotherapy is one of the most effective cancer treatments, but it can be hard on the body. The human body doesn’t like being injected with radioactive material, especially the skin around the injection point, which can become extremely irritated. For patients in long-term treatment, the skin irritation can be more than just a bother; it can lead to infections that are dangerous to a compromised immune system.

Angel A Marti, a professor of chemistry at Rice University, and Biana Godin, an associate professor of nanoscience at Houston Methodist Research Institute, are experimenting with metal nanoclusters as a way to block radiation at the injection site. The nanocluster could be applied in a cream or a gel on the skin, serving as a type of shield against the harsh radioactive material.

Meanwhile, Yuan Ma, an assistant professor of chemistry at Rice, and Shu-Hsia Chen, a professor of immunology at Houston Methodist Research Institute, are working with m6A. Discovered in the 1970s, m6A is the most prevalent chemical modifier found in mRNA in mammals. It is prevalent in many cancers, including leukemia.

Ma and Chen are working on measuring the amount of m6A in leukemia to see if it can determine the most effective cancer treatments. The team is also experimenting with ways to shut off m6A to see if it makes current leukemia treatments more effective.

Progress from SynthX

SynthX was first launched in April 2024 to turn research from Rice and Houston Methodist into real-world cancer treatments. Within a year, the center had secured $1.5 million in grant money to work on crossing the blood-brain barrier in brain cancer treatments. These latest awards show that SynthX Center continues to bridge the worlds of research and clinical practice.

“This collaboration reflects a shared commitment to team science in cancer research,” Daniela Matei, the director of the Houston Methodist Neal Cancer Center, added in the release. “These are the types of translational and pioneering projects that lead to transformation in patient care.”'

The SynthX Center awarded $90,000 in seed grants to three teams in 2025 and $80,000 to three teams in 2024.

Tesla self-driving mode wasn't to blame in Houston-area crash, report suggests

Tesla news

Federal safety investigators looking into a runaway Tesla that killed a grandmother in her home say the driver had pressed the accelerator to full speed, suggesting the vehicle's self-driving software was not to blame.

The driver had told police that he had the self-driving software turned on, but a report from the National Transportation Safety Board concluded that he had actually overridden that feature when he pushed hard on the pedal. Moments later the Tesla Model 3 raced down a residential street in Katy, Texas, at highway speeds, slammed into a brick home and killed a 76-year-old woman standing in the front room.

The crash last month drew national attention because Tesla CEO Elon Musk is seeking to reassure the public its self-driving feature is safe as he prepares to turn hundreds of thousands of Teslas already on the road into fully automatic vehicles and begin selling two-seated Cybercabs missing steering wheels and pedals.

The crash came two months after officials at a separate federal agency, the National Highway Traffic Safety Administration, announced it was elevating a 2024 investigation of the self-driving feature to new “engineering analysis” level, raising the possibility of a recall of 3.2 million Tesla vehicles.

That NHTSA probe was triggered by crashes where the self-driving feature failed to alert drivers to take control in fog and other poor visibility conditions.

The agency opened an investigation last year into 58 incidents in which Teslas reportedly violated traffic safety laws while using self-driving technology, leading to more than a dozen crashes and fires and nearly two dozen injuries.

Separate from the National Transportation Safety Board, NHTSA is also looking into the Tesla house crash in Texas, one of 46 “special crash” investigations of Tesla's self-driving or driver-assistance technology in the past decade, according to the agency’s records. In more than a dozen of those crashes, at least one person — a driver, passenger or pedestrian — was killed.

Tesla had originally called its driver assistance software Full Self-Driving, or FSD, but auto experts and regulators complained it was misleading because drivers must always keep their eyes on the road and be ready to take over at any time.

The company has since changed the name to Full Self-Driving (Supervised).

Video of the Katy, Texas, accident shows the Tesla traveling at more than 70 mph (112.65 kilometers per hour), jumping a curb then tearing across a lawn before crushing through a brick wall of a home. A woman standing feet away, Martha Avila, was found amid piles of crumbling plaster, split beams and bits of furniture and rushed to a hospital but died.

Sales of Tesla cars still haven't recovered fully from boycotts last year over Musk's political stands, but the stock is rising anyway as he has successfully shifted attention away from the sales figures. He says they matter less now that the company is on the cusp of major technological advances, such as turning Teslas into hands-free vehicles and having its Optimus robots take over for humans for tasks at home and work.

Tesla stock has risen 22% in the past year and is currently trading at 170 times expected annual earnings compared to 20 for the S&P 500.

For its second-quarter financial results, financial analysts surveyed by FactSet expect earnings per share will barely budge — 32 cents versus 33 cents a year earlier — continuing a sixth quarter streak of flat or falling profits.

London AI startup selects Houston for first U.S. office after $20M raise

welcome to houston

London-based AI firm Applied Computing has announced a $20 million Series A round and a new office in Houston.

The new Bayou City office is Applied Computing’s first in the United States and part of its North American expansion. The company is known for its Orbital AI platform, which is tailored for energy operations.

The funding round was led by Houston-based KBR Inc., with participation from San Francisco-based Databricks Ventures. KBR’s investment was first announced in March.

KBR and Applied Computing have also entered into a multi-year agreement to deliver exclusive AI products for the energy sector. KBR already has integrated Orbital into its INSITE 3.0 platform for energy projects, and is also using the product for ammonia production.

Applied Computing’s Orbital platform combines physics-grounded intelligence with models across chemical engineering, time-series forecasting and language, according to the company. The system analyzes sensor readings and can recognize a facility’s equipment constraints and operator activity. The platform can also allow technicians to run simulations of how a change to a facility could affect the rest of its operations.

According to TechCrunch, Applied Computing will use the $20 million to further explore projects and deployments with the energy sector, hire engineering and research positions, and continue to expand internationally, potentially into the Middle East.

The company is also working on deals with a major U.S. stream operator, TechCrunch reports. And Applied Computing shared on LinkedIn that it plans to announce its first partnership with a major European oil company in the coming weeks.

“Yesterday we showed Orbital live in deployments at our demo day at the Energy Institute in London,” Callum Adamson, CEO and co-founder of Applied Computing, posted on LinkedIn on July 16. “Today, we're announcing the capital to scale it globally as well as the launch of our new offices in Houston and Bangalore. In the weeks following, there will be more announcements on our progress, partnerships and deployments.”

The company opened its Bangalore offices in December.

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