Overheard: Why these 3 startups relocated to Houston

eavesdropping at the houston innovation awards gala

Here's why three New to Hou finalists from the Houston Innovation Awards have committed to Houston. Photo via Getty Images

Houston is attracting more and more businesses big and small, old and new. So much that it seemed worthy of an award for the Houston Innovation Awards Gala.

The awards event, which is on November 9 and hosted by InnovationMap and Houston Exponential at the Ion, is honoring five finalists selected by judges — and naming one winner — who have recently relocated or significantly expanded to Houston.

Here's why three of these New to Hou finalists have committed to Houston.

"The move to the Houston area allowed us to be much closer to our strategic partners, customers and suppliers. We are also impressed by the vast talent pool in the area. Houston has a highly skilled workforce with diverse experiences, particularly in oil and gas, petrochemicals, and a broad range of technical areas."

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— Jay Manouchehri, CEO of Fluence Analytics, which relocated from Louisiana to Stafford last year, just outside of Houston. "We have been able to engage very actively with many customers since the move and also have developed valuable supplier relationships."

"In 2019, Chevron and EIC (both Houston based) became investors and we already had a lot of US clients, so we wanted to create a Houston footprint."

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— John van Pol, co-founder and CEO of INGU, which opened its new Houston office in 2021. Van Pol adds that the pandemic delayed their expansion initially.

"Houston has a quickly-growing biotechnology sector and already has existing oil and gas talent, making it an ideal place to find the people we need to grow our business."

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— Zimri T. Hinshaw, founder and CEO of BUCHA BIO, which relocated to Houston from New York in January 2022. "Our most prominent investor is Houston-based New Climate Ventures," he adds.

INGU Solutions has established its U.S. office in Houston — and is ready to tap into the city's energy industry with its revolutionary pipeline inspection-as-a-service model. Photo via ingu.com

Innovative Canadian company taps into Houston market to better serve energy customers

in the pipeline

On average, oil and gas pipelines are inspected every five years, which, considering pipelines in the United States are more than 60 years old, just isn't cutting it. Operators face costly and damaging leaks on cracks and incidences that are totally avoidable with more regular inspection. The issue is inspection isn't an easy process — unless INGU Solutions is involved.

The Alberta, Canada-based company has created a hardware component — called a Piper — that's about the size of a baseball. The device can be run through pipes of any size to inspect and detect internal issues. INGU has an inspection-as-a-service model so that whatever data is collected by the Pipers is analyzed and provided to clients without any more steps from them.

The idea for the device came to John van Pol, founder and CEO, who has a background in nuclear physics and founded the company in 2015. Now, he runs the company with his daughter, Anouk van Pol, who started as an analyst and working in the field for INGU and now serves the company as co-founder and COO.

The Piper is smaller than a baseball and can flow through any sized pipe used in the oil and gas industry. Photo via ingu.com

In 2017, INGU was selected to be a part of Chevron's inaugural Catalyst Program cohort and Chevron Technology Ventures — along with two other U.S. investors — contributed to the company's series A round in 2019. This led to INGU establishing its U.S. operations in Houston in order to grow their American team and to be closer to customers. Then, the pandemic hit.

“The idea was to be closer to our customers,” Anouk tells InnovationMap. “Houston is the oil and gas hub, and just being able to be in [our clients'] offices and be there in person it just helps. I hope at one point COVID passes and that we can make use out of it a bit more.

"The other thing is you open up your market on the hiring side," she says, adding that the company has two U.S. employees now.

INGU first had an office in The Cannon, but now operates locally at The Ion in the Common Desk coworking space with an office suite to support its local team. In 2019, the company was named to Plug and Play's inaugural Houston cohort and as a most-promising business by Rice Alliance at OTC.

Anouk, who was selected for Forbes 30 Under 30 in energy in 2020, and her father both split their time between Houston and Alberta, usually alternating so that the van Pols have a presence in each office at all times, but both are currently in town for the 34th annual Pipeline Pigging and Integrity Management conference, or PPIM. It's the OTC for the pipeline industry, Anouk says.

Ahead of the conference and despite the challenges the pandemic has posed for INGU, Anouk says the company has seen significant growth over the past two years.

"We grew 60 percent last year," she says. "which is pretty good for what's been happening over the past two years."

From a hardware perspective, the pandemic's impact has been relatively small. The Pipers are designed with off-the-shelf materials, which INGU stocked up on — avoiding any supply chain shortages. Additionally, INGU can send the devices to pipeline operators, who can deploy them while the devices send the collected data directly to INGU.

Anouk van Pol is the company's COO. Photo via LinkedIn

The company, which anticipates a secondary series A round this year in addition to tripling its annual revenue, has an environmental, social, and governance, or ESG, component to its business. While half of INGU's clients are in the energy industry and Pipers contribute to reducing waste within oilfield operations, the other half of customers are within the water industry. Water infrastructure is 100 years old, and Anouk says about 6 billion gallons of water are wasted each day.

"That's 40 percent of all water, and because so much water is lost, you need more power and energy," Anouk says. "Where we see oil and gas is aimed at prevention in well condition, etc., the water market is doing a lot of leak protection."

In both industries, Pipers are preventing waste and allowing companies to make positive moves in their ESG plans.

INGU has clients all over the world and servicing these various types of pipes and businesses is growing INGU's database, which better benefits their inspection-as-a-service capabilities.

"The more we grow, the more we can and will learn, and then go in this self-fulfilling cycle," Anouk says.

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Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

Elon Musk's SpaceX site officially becomes the city of Starbase, Texas

Starbase, Texas

The South Texas home of Elon Musk’s SpaceX rocket company is now an official city with a galactic name: Starbase.

A vote Saturday, May 3, to formally organize Starbase as a city was approved by a lopsided margin among the small group of voters who live there and are mostly Musk’s employees at SpaceX. With all the votes in, the tally was 212 in favor to 6 against, according to results published online by the Cameron County Elections Department.

Musk celebrated in a post on his social platform, X, saying it is “now a real city!”

Starbase is the facility and launch site for the SpaceX rocket program that is under contract with the Department of Defense and NASA that hopes to send astronauts back to the moon and someday to Mars.

Musk first floated the idea of Starbase in 2021 and approval of the new city was all but certain. Of the 283 eligible voters in the area, most are believed to be Starbase workers.

The election victory was personal for Musk. The billionaire’s popularity has diminished since he became the chain-saw-wielding public face of President Donald Trump’s federal job and spending cuts, and profits at his Tesla car company have plummeted.

SpaceX has generally drawn widespread support from local officials for its jobs and investment in the area.

But the creation of an official company town has also drawn critics who worry it will expand Musk’s personal control over the area, with potential authority to close a popular beach and state park for launches.

Companion efforts to the city vote include bills in the state Legislature to shift that authority from the county to the new town’s mayor and city council.

All these measures come as SpaceX is asking federal authorities for permission to increase the number of South Texas launches from five to 25 a year.

The city at the southern tip of Texas near the Mexico border is only about 1.5 square miles (3.9 square kilometers), crisscrossed by a few roads and dappled with airstream trailers and modest midcentury homes.

SpaceX officials have said little about exactly why they want a company town and did not respond to emailed requests for comment.

“We need the ability to grow Starbase as a community,” Starbase General Manager Kathryn Lueders wrote to local officials in 2024 with the request to get the city issue on the ballot.

The letter said the company already manages roads and utilities, as well as “the provisions of schooling and medical care” for those living on the property.

SpaceX officials have told lawmakers that granting the city authority to close the beach would streamline launch operations. SpaceX rocket launches and engine tests, and even just moving certain equipment around the launch base, requires the closure of a local highway and access to Boca Chica State Park and Boca Chica Beach.

Critics say beach closure authority should stay with the county government, which represents a broader population that uses the beach and park. Cameron County Judge Eddie Trevino, Jr. has said the county has worked well with SpaceX and there is no need for change.

Another proposed bill would make it a Class B misdemeanor with up to 180 days in jail if someone doesn’t comply with an order to evacuate the beach.

The South Texas Environmental Justice Network, which has organized protests against the city vote and the beach access issue, held another demonstration Saturday that attracted dozens of people.

Josette Hinojosa, whose young daughter was building a sandcastle nearby, said she was taking part to try to ensure continued access to a beach her family has enjoyed for generations.

With SpaceX, Hinojosa said, “Some days it’s closed, and some days you get turned away."

Organizer Christopher Basaldú, a member of the Carrizo/Comecrudo Nation of Texas tribe, said his ancestors have long been in the area, where the Rio Grande meets the Gulf.

“It’s not just important,” he said, “it’s sacred.”

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