Houston innovator shares investment opportunities outside traditional VC model

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Angel investors, corporate venture, and more options for Houston startups outside of the traditional venture capital model.

In my last column about tapping into Houston's venture capital ecosystem, I identified the 31 venture capitalists in Houston. By most measures Houston is around 0.5 to 1 percent of US venture capital activity, and that low volume is reflected in the limited number of venture capitalists locally.

But outside of venture capital funds, founders often pull money from other places including angel investors, seed funds and corporate venture capital arms as well as cross-over investors. I got asked this morning by a founder at the Ion, where’s the rest of the list?

Houston has five active corporate venture capital funds, or CVCs, with at least one senior investment professional in Houston with and one with headquarters here (Chevron). A short list of the key investment professionals in the group includes:

There are maybe half a dozen other corporates In Houston that organize around a fund structure and governance of some type, and have been actively investing in venture capital rounds with professionals in Houston. Equinor, a long time corporate investor, Baker Hughes which relaunched a CVC effort in 2021, Mitsubishi has investment professionals in Houston, and Williams which launched a new CVC effort in 2022, as well as Occidental, BHP, and Waste Management which had active CVC efforts in the past that have gone a bit on ice, as did ConocoPhillips, P66 and Schlumberger. Two larger private equity funds Ara Partners and Quantum are active in venture capital deals, but in a more mixed model. This universe would probably add another 30 to 40 Houston based active investment professionals.

The city also has around 10 angel networks, pre-seed funds, pre-seed investors, and accelerators that write checks, typically in the $100K to $1 million range, but either without committed venture funds in an acceleration model, at varying degrees of active, scale, model, and type.

Layering them in no particular order the Houston universe expands by another dozen full time or mostly full time professionals, and a few dozen angels. I’ve included their main contacts below:

These are certainly not large numbers for a city our size, and commensurate with the size of the Houston startup market. But while the cupboard may be a bit bare, it’s not empty. As a founder chasing money, that’s about 75 to 100 names to go chase, with probably double that in active or semi-active angel investors investing through these pools.

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Neal Dikeman is a venture capitalist and seven-time startup co-founder investing out of Energy Transition Ventures.

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John "JR" Reale joins the Houston Innovators Podcast for a two-part series of interviews discussing Houston innovation, the Texas Medical Center, investment trends, and more. Photo via TMC.edu

Longtime Houston innovator talks investment trends and ecosystem evolution

houston innovators podcast episode 136

Over the years, John "JR" Reale may have transitioned to various roles within the Houston innovation ecosystem, but the people he was working with stayed the same.

"My focus is always on partnering with founders — I just get to do it with two amazing hats," Reale says on this week's episode of the Houston Innovators Podcast.

Those two hats are as executive in residence at Texas Medical Center Innovation and as managing director of Integr8d Capital, an early-stage fundless venture capital firm that invests with intentionality. Reale joined the podcast for a special two-part series. The first episode is out now and focuses on his career in innovation and investment. The second part, which comes out next week, covers health tech innovation and his work with Texas Medical Center.

Most people might know Reale as one of the co-founders of Station Houston, a hub for tech innovation and entrepreneurship that launched in 2015 and dissolved into a few entities like The Ion and Capital Factory in 2018. Reale says on the show that Station's success came at a crucial time for Houston.

"Our big insight was ultimately around two things. One, we had a great empathy about how lonely and challenging it is being a founder. It was about building an authentic community where folks wanted to be," Reale says on the show. "Later in 2016 and 2017, we had this idea of separating space for the services and the things that founders need — especially in a big city like Houston."

Reale says Station was focused on the founders and providing a centralized location for support — something that sprawling Houston didn't have before.

"Our mission was really simple," he says, "it was to serve entrepreneurs. We knew who we wanted to serve, and we knew it meant a lot of different things."

Around the time of Station, Mayor Sylvester Turner's office asked Reale to join a task force with Amanda Edwards and several other impactful parties. The mission there was to get everyone on the same page and not only see the city's potential for innovation, but work on developing it.

"We went through a journey as a task force," Reale says. "A lot of it was about learning together. One of the big insights were about meeting people where they were. You're bringing all different pockets of the community together, and it's not about dictating what people have to do."

When it comes to pointing to a turning point in Houston, Reale doesn't mince words.

"One of the most important moments for Houston was when we got kicked in the teeth with the Amazon HQ2 bid," he says. "Amazon came back with the shortlist of the 20 cities in North America — and Houston isn't on it. I remember being excited. It was arguably the most innovative company in the world saying 'no thank you.'"

Rather than feel defeated or disappointed, Reale says he was excited about the rejection. It was an opportunity to spur more work that needed to be done.

"That was the gut punch that folks needed to realize," he says. "Moments like that cause real reflection. Failure like that forces you to ask a different set of questions."

The pandemic has meant for another, though very different, turning point and opportunity — especially when it comes to investment.

"Over the last few years we've seen a positive impact of the pandemic — it's changed the barriers to capital coming into different geographies, and I think that's sustainable. We've created new norms and behaviors of where capital will go," he says.

There's still room to grow and opportunities to come to fruition — especially within the early-stage investment community, Reale says.

"I'd like to see more funds launch here with very intentional strategies — particularly seed and early-stage work. You usually find those to be more geographically close," he says. "That's an opportunity. And I'd like to see more awesome operators turned investors."

Reale shares more about Integr8d Capital and what he's working on now on the podcast episode, as well as in next week's episode. Listen to the first interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


Houston-based data management startup Graylog has fresh funds to fuel its growth. Photo via Graylog.org

Houston data management company closes $18M in fresh funding

money moves

A Houston company that's created a centralized log management solution has closed a new round in funding.

Graylog closed its $18 million growth equity round led by Richmond, Virginia-based Harbert Growth Partners, a new investor, and Minneapolis, Minnesota-based Piper Sandler Merchant Banking, the company announced today. The round also received contribution from existing investors Houston-based Mercury Fund and Integr8d Capital, as well as Germany-based HTGF.

"This investment will enable us to accelerate our global go-to-market strategies and enhancements to the award-winning solutions we deliver for IT, DevOps, and Security teams," says Andy Grolnick, CEO of Graylog, in a press release. "We're excited to have the support of new and existing investor partners to help us realize our potential."

Andy Grolnick is CEO of Graylog. Photo courtesy

Per the release, the funds will go toward growing the company's platform that allows its users the ability to capture, store, and enable real-time analysis of terabytes of machine data.

"Graylog is well-positioned to be a long-term winner in the rapidly growing market for log management and analysis solutions," says Brian Carney, general partner of Harbert Growth Partners, in the release. "With its focus on delivering a superior analyst experience coupled with a vibrant Open Source community, the company provides customers a compelling alternative to other log management solutions plagued with high complexity and high total cost of ownership (TCO). We are thrilled to partner with the Graylog team to leverage the significant opportunity that lies ahead for the company."

Over the past year, despite the challenging business climate, the company saw growth in business and even expanded its European operations, according to the release.

"As a long-standing customer, Graylog is strategic to our success. We are excited to see new investment that will enable the company to accelerate innovation and continue to deliver excellent log management and SIEM solutions," says Rob Reiner, CTO of PROS, in the release.

Venture Houston brought together key innovators and investors focused on Houston — here's what they said. Photo via Getty Images

Overheard: Here's what experts say on the future of startup investment in Houston

eavesdropping in houston

Last week, over 2,500 people registered to Venture Houston to talk about startups and venture capital in Houston for two full days.

The two-day conference, which was put on by HXVF, the Houston Angel Network, the Rice Alliance, and Houston Exponential, took place February 4th and 5th and brought together startups, investors, corporations, and anyone who cares to advance the Houston tech ecosystem.

Click here to see what companies won big in the event's startup pitch competition.

Throughout the various panels and keynote addresses, Houston innovation leaders sounded off on what the future of Houston looks like in terms of venture activity. Missed the discussion or just want a refresher on on the highlights? Here are some significant overheard moments from the virtual conference.

“The way I look at it, Houston has an opportunity to really emerge as one of the leading startup cities in the country.”

— Steve Case, chairman and CEO of Revolution Ventures and co-founder of AOL.

He makes a reference to the iconic line "Houston, we have a problem" — which now is defined by a time of opportunity. Case adds that his VC fund, Revolution, which has invested in Houston-based GoodFair, is looking for new investments in Houston.

“We were behind. We were slow to start, but in typical Houston fashion, now we are escalating with real momentum."

— Amy Chronis, Houston managing partner of Deloitte and 2021 Greater Houston Partnership board chair.

Chronis notes on the fact that VC activity in Houston is up 250 percent since 2016, and in that time the city has focused on diversifying its business. Now, the city touts its active corporate community, global diversity, and more.

"In Houston, companies and talent are looking at ways to change the world," she adds.

“I see there being a significant amount of seed capital taking off.”

— Stephanie Campbell, managing director of the Houston Angel Network and The Artemis Fund.

Campbell calls out new funds to Houston, like Golden Section Ventures and her own fund, Artemis. She adds that with over $700 million invested in Houston deals last year, the city is in a good place, and she is anticipating more angel activity.

"While this is really exciting progress, there's still a lot of work to be done in terms of seed and early-stage funding," she continues.

“I see there being billion-dollar venture funds here in Houston on the life science front over the next decade.”

— John "JR" Reale, managing director of Integr8d Capital.

Reale, who's also the executive in residence at TMC Innovation, says he's seen the growth and potential of the life science industry in Houston.

"You can see the intentionality of the infrastructure that's being built that's going to attract diverse founders and all talent," he says.

“What I really see is the trajectory for Houston has been changing over the last couple years.”

— Brad Burke, managing director for the Rice Alliance for Technology and Entrepreneurship.

Burke points to three things that have really moved the needle on Houston's progress as an innovative city. The first was the Texas Medical Center establishing its Innovation Institute a few years back, and the next is how Houston's top energy companies are making big moves to support the energy transition. Finally, he says, The Ion, which is set to open this year, is the third reflection point for progress.

“The Houston startup scene is a very special place. It’s a community I actively choose to be a part of, and it activates me every day.”

— Rakesh Agrawal, CEO and founder of SnapStream.

“We’ve got a really incredible story to tell.”

— Susan Davenport, senior vice president of economic development for the GHP.

Davenport adds that this is exactly what the GHP is doing — making Houston's story known. And she says they have talked to global business leaders and they describe the city as a modern, cosmopolitan, truly global city.

Here's who won big for Houston innovation. Photos courtesy

Houston Exponential names winners of inaugural innovation awards

And the winner is...

In a virtual awards program, Houston Exponential has revealed the winners of the inaugural Listies awards.

The Listies, brought to you by Houston Exponential in partnership with InnovationMap, named the winning companies and people across 12 awards on November 20 at 3 pm as a part of Impact Hub's annual The Houston Innovation Summit (THIS).

Nominations were open until Friday, November 6, and then a group of judges made up of members of the Houston innovation ecosystem reviewed the submissions to settle on the 38 finalists. Click here to see the finalists.

Here's who took home the big wins.

SDO Superstar: MassChallenge Texas

Photo courtesy of MassChallenge

A startup development organization can be an accelerator program, an incubator, or a coworking space — and organizations falling into all three of these sectors were nominated for this category. MassChallenge Texas, which has been running its non-equity, general accelerator program in Houston for two years, stood out to judges to take the win for the SDO Superstar category.

Individual Contributor: Slawek Omylski of SecurityGate

Photo via LinkedIn

The individual contributor award was meant to find and recognize a non-founder who was essential to the success of a Houston startup, and that's exactly how SecurityGate's team sees Slawek Omylski, director of engineering. Not only has he been essential from the start over three years ago when he joined as employee No. 4, but Omylski, when unexpectedly having to move back home to Italy, never missed a single meeting or tech deployment despite being an ocean away from the rest of his team. Known as "Suave" by his teammates, his nominators say Omylski is usually the first to arrive at the office and the last to leave.

Civic Innovation: Annapurna Solutions

Image viaannapurnasolutions.org

Everyone knows that the key to sustainability is reducing, reusing, and recycling, but the fact of the matter is no one has quite perfected recycling. Houston-based Annapurna Solutions is stepping in to help. The company provides innovative technology solutions to address waste and recycling challenges, helping to make cities smart and sustainable — like the company's ReciklApp.

Welcome to Houston: Greentown Labs

Photo via greentownlabs.com

Greentown Labs is a startup development organization, but it's are also a startup itself, but when it opens its doors in Houston in the spring, the organization isn't starting from scratch. After years of working with over 200 climatech companies in the Boston area, Greentown's expansion into Houston means incubating Houston energy tech companies and furthering the conversation and activation within the energy transition.

Investor of the Year: Integr8d Capital

Photo via TMC.edu

John "J.R." Reale has been a well respected mentor, entrepreneur, and investor in Houston for years. His firm Integr8d Capital has invested in several Houston companies, including Liongard from seed stage to series A and series B. Reale is also the entrepreneur in residence for the TMC Innovation Institute.

Corporate Innovator: Houston Methodist

Courtesy of Methodist Hospital/Facebook

Houston Methodist and its Center for Innovation led by Roberta Schwartz is leading health tech innovation in Houston. In January, the hospital opened its Technology Hub, 3,500-square-foot space renovated from a former 18-room patient wing to showcase and test new digital health technologies like virtual reality, ambient listening, wearables, and more. Additionally, the hub helped with the training of dozens of doctors with the rise of telemedicine during COVID-19.

Outstanding Leadership: Grace Rodriguez

Photo courtesy of Grace Rodriguez

Grace Rodriguez's career spans industry and time, but her leadership has been consistent throughout. She currently serves Impact Hub Houston as CEO and executive director. Her nominator calls her an inspiration and someone who "shows up," clearly loving everything she does and is responsible. During COVID-19, she's gone above and beyond to provide resources and information to everyone who needs it, including launching a fund to help pay for meals for health care workers and first responders. The LIFE Fund raised over $20,000.

COVID Phoenix: Luminare

Image via luminaremed.com

Originally founded by Dr. Sarma Velamuri to treat and fight sepsis, Luminare took its sepsis platform and pivoted it to created a COVID self-assessment and testing tool. Their digital platform directed 5.5 million people to COVID-19 testing sites in just 21 days, according to its nomination. The tool was used by Harris County and several other entities.

DEI Champion: Maria Maso

Photo courtesy of Nijalon Dunn

Maria Maso is looking out for minorities when it comes to investment. As the founder and CEO of the Business Angel Minority Association (baMa) — an Angel Association aimed at bridging minority-founded startups with accesses to capital — Maria has been a champion for diversity. She also has helped to educate and activate 40 diverse investors through baMa's Diversity Investor Academy, according to her nomination.

Mentor of the Year: Landi Spearman

Photo via LinkedIn

Landi Spearman's approach to mentorship, according to her nominee, is to mentor the full person — from professional to personal life — through Organized SHIFT, which focuses on helping highly productive leaders, individuals and organizations in their quest to sustain positive growth internally and externally. She also supports entrepreneurs though The Ion, Station Houston, General Assembly, the National Urban League, Power to Fly, Black Women in Science and Engineering, the Greater Houston Partnership, the Greater Houston Black Chamber, Pink Petro, and more.

People's Choice and Soonicorn: Liongard

Photos via LinkedIn

People's Choice was based off how many nominations the startups received, and Liongard was a clear winner. The company, which also won in the Soonicorn category, has experienced major growth and, as the nominations read, that's to both Joe Alapat and Vincent Tran, co-founders, credit. The company has raised $12 million to date — the most recent round, a $10 million Series A — closed this year.

Houston Exponential has announced the 38 finalists for the inaugural Listies Awards. Photo via Getty Images

Exclusive: HX names finalists for inaugural Houston innovation awards

the listies go to...

Ever wonder what Houston startups and innovators are the best of the best? Here's your chance to figure it out. The inaugural Listies awards program has named its finalists.

The Listies, brought to you by Houston Exponential in partnership with InnovationMap, will name the winning companies and people across 12 awards on November 20 at 3 pm at a virtual event as a part of Impact Hub's annual The Houston Innovation Summit (THIS). Click here to register for the free event.

Nominations were open until Friday, November 6, and then a group of judges made up of members of the Houston innovation ecosystem reviewed the submissions to settle on the finalists. Below, in alphabetical order, the 38 finalists are listed for each category.

DEI champion

  • Heath Butler
  • Maria Maso
  • Grace Rodriguez

Individual contributor

  • Michael Matthews
  • Slawek Omylski
  • Brad True

Mentor of the year

  • Keith Kreuer
  • Wade Pinder
  • Landi Spearman

Outstanding leadership

  • Stephanie Campbell
  • Grace Rodriguez
  • Roberta Schwartz

Corporate innovation

  • Chevron Technology Ventures
  • Houston Methodist
  • Shell Ventures

Investor of the year

  • CSL Capital Management
  • Golden Section VC (GSTVC)
  • Integr8d Capital

SDO superstar

  • MassChallenge Houston
  • Rice Alliance
  • TMCx

Welcome to Houston

  • Greentown Labs
  • TestCard
  • Win-Win

Civic engagement

  • Annapurna
  • Luminare
  • McMac Cx

COVID pivot/phoenix

  • Luminare
  • re:3D
  • sEATz

People choice

  • INK
  • Liongard
  • Luminare
  • re:3D
  • Topl

Soonicorn

  • GoExpedi
  • Liongard
  • Medical Informatics Corp.
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Trailblazing Houston entrepreneur brings big ideas to new Yahoo Finance show

tune in

Elizabeth Gore, co-founder and president of Houston's Hello Alice, debuted the first episode of her new video podcast series with Yahoo Finance on Thursday, April 24.

The weekly series, known as "The Big Idea with Elizabeth Gore," will focus on providing information and resources to small business owners and sharing stories of entrepreneurship, according to a news release from Yahoo Finance.

“Entrepreneurs and small business owners drive our country’s economy forward. With a record number of small businesses launching in our communities, my goal is to help every citizen live the American Dream. On the Big Idea, we will break down barriers for entrepreneurs and lift up opportunities for every person wanting to be their own boss,” Gore said in the release.

“By hosting the 'Big Idea' on Yahoo Finance, I’m looking forward to elevating business owners’ stories and providing actionable insights to small business owners at a scale like never before. I am blown away to be joining the number one finance news source that is already trusted by so many.”

Gore was joined by Hello Alice co-founder and CEO Carolyn Rodz in the premiere episode, titled "Got a big idea for a small business? Here's your first step," to discuss the steps they took when launching the business.

Gore and Rodz founded Hello Alice in 2017. The fintech platform supports over 1.5 million small businesses across the nation. It has helped owners access affordable capital and credit and distributed over $57 million in grants to businesses across various industries. The company raised a series C round backed by Mastercard last year for an undisclosed amount and reported that the funding brought the company's valuation up to $130 million at the time.

According to Yahoo Finance, Gore's experience and expertise build on its "mission to be the trusted guide of financial information to all investors, and democratize access to quality content."

“Over the past year, we invested in expanding our programming lineup with the launch of new shows and podcasts, and welcomed new financial creators and influencers into our newsroom,” Anthony Galloway, head of content at Yahoo Finance, added the release. “By diversifying our programming and talent roster, Yahoo Finance is introducing unique points-of-view that make financial topics more engaging, actionable, and personalized. Small business owners are a vital part of our audience, so we’re excited to welcome Elizabeth Gore from Hello Alice, whose insights and expertise will help us serve and connect with this important cohort in meaningful ways.”

The show is available on Spotify, Apple Podcasts, iHeart, Pandora, and Amazon Music for listening. Streamers can view it on yahoofinance.com, Amazon Prime Video, Samsung TV, Fire TV, Vizio, Haystack, DirectTV and other streaming platforms. Watch the premiere here:

7 top Houston researchers join Rice innovation cohort for 2025

top of class

The Liu Idea Lab for Innovation and Entrepreneurship (Lilie) has announced its 2025 Rice Innovation Fellows cohort, which includes students developing cutting-edge thermal management solutions for artificial intelligence, biomaterial cell therapy for treating lymphedema, and other innovative projects.

The program aims to support Rice Ph.D. students and postdocs in turning their research into real-world solutions and startups.

“Our fourth cohort of fellows spans multiple industries addressing the most pressing challenges of humanity,” Kyle Judah, Lilie’s executive director, said in a news release. “We see seven Innovation Fellows and their professors with the passion and a path to change the world.”

The seven 2025 Innovation Fellows are:

Chen-Yang Lin, Materials Science and Nanoengineering, Ph.D. 2025

Professor Jun Lou’s Laboratory

Lin is a co-founder of HEXAspec, a startup that focuses on creating thermal management solutions for artificial intelligence chips and high-performance semiconductor devices. The startup won the prestigious H. Albert Napier Rice Launch Challenge (NRLC) competition last year and also won this year's Energy Venture Day and Pitch Competition during CERAWeek in the TEX-E student track.

Sarah Jimenez, Bioengineering, Ph.D. 2027

Professor Camila Hochman-Mendez Laboratory

Jimenez is working to make transplantable hearts out of decellularized animal heart scaffolds in the lab and the creating an automated cell delivery system to “re-cellularize” hearts with patient-derived stem cells.

Alexander Lathem, Applied Physics and Chemistry, Ph.D. 2026

Professor James M. Tour Laboratory

Lathem’s research is focused on bringing laser-induced graphene technology from “academia into industry,” according to the university.

Dilrasbonu Vohidova is a Bioengineering, Ph.D. 2027

Professor Omid Veiseh Laboratory

Vohidova’s research focuses on engineering therapeutic cells to secrete immunomodulators, aiming to prevent the onset of autoimmunity in Type 1 diabetes.

Alexandria Carter, Bioengineering, Ph.D. 2027

Professor Michael King Laboratory

Carter is developing a device that offers personalized patient disease diagnostics by using 3D culturing and superhydrophobicity.

Alvaro Moreno Lozano, Bioengineering, Ph.D. 2027

Professor Omid Veiseh Lab

Lozano is using novel biomaterials and cell engineering to develop new technologies for patients with Type 1 Diabetes. The work aims to fabricate a bioartificial pancreas that can control blood glucose levels.

Lucas Eddy, Applied Physics and Chemistry, Ph.D. 2025

Professor James M. Tour Laboratory

Eddy specializes in building and using electrothermal reaction systems for nanomaterial synthesis, waste material upcycling and per- and polyfluoroalkyl substances (PFAS) destruction.

This year, the Liu Lab also introduced its first cohort of five commercialization fellows. See the full list here.

The Rice Innovation Fellows program assists doctoral students and postdoctoral researchers with training and support to turn their ideas into ventures. Alumni have raised over $20 million in funding and grants, according to Lilie. Last year's group included 10 doctoral and postdoctoral students working in fields such as computer science, mechanical engineering and materials science.

“The Innovation Fellows program helps scientist-led startups accelerate growth by leveraging campus resources — from One Small Step grants to the Summer Venture Studio accelerator — before launching into hubs like Greentown Labs, Helix Park and Rice’s new Nexus at The Ion,” Yael Hochberg, head of the Rice Entrepreneurship Initiative and the Ralph S. O’Connor Professor in Entrepreneurship, said in the release. “These ventures are shaping Houston’s next generation of pillar companies, keeping our city, state and country at the forefront of innovation in mission critical industries.”

Houston startup Collide secures $5M to grow energy-focused AI platform

Fresh Funds

Houston-based Collide, a provider of generative artificial intelligence for the energy sector, has raised $5 million in seed funding led by Houston’s Mercury Fund.

Other investors in the seed round include Bryan Sheffield, founder of Austin-based Parsley Energy, which was acquired by Dallas-based Pioneer Natural Resources in 2021; Billy Quinn, founder and managing partner of Dallas-based private equity firm Pearl Energy Investments; and David Albin, co-founder and former managing partner of Dallas-based private equity firm NGP Capital Partners.

“(Collide) co-founders Collin McLelland and Chuck Yates bring a unique understanding of the oil and gas industry,” Blair Garrou, managing partner at Mercury, said in a news release. “Their backgrounds, combined with Collide’s proprietary knowledge base, create a significant and strategic moat for the platform.”

Collide, founded in 2022, says the funding will enable the company to accelerate the development of its GenAI platform. GenAI creates digital content such as images, videos, text, and music.

Originally launched by Houston media organization Digital Wildcatters as “a professional network and digital community for technical discussions and knowledge sharing,” the company says it will now shift its focus to rolling out its enterprise-level, AI-enabled solution.

Collide explains that its platform gathers and synthesizes data from trusted sources to deliver industry insights for oil and gas professionals. Unlike platforms such as OpenAI, Perplexity, and Microsoft Copilot, Collide’s platform “uniquely accesses a comprehensive, industry-specific knowledge base, including technical papers, internal processes, and a curated Q&A database tailored to energy professionals,” the company said.

Collide says its approximately 6,000 platform users span 122 countries.

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This story originally appeared on our sister site, EnergyCapitalHTX.com.

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