3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Spencer Randall of CryptoEQ, Andy Grolnick of Graylog, and Imran Alibhai of Tvardi. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from software to cryptocurrency — recently making headlines in Houston innovation.

Spencer Randall, co-founder and principal at CryptoEQ

Spencer Randall, principal and co-founder of CryptoEQ, joins the Houston Innovators Podcast to discuss how his company has grown alongside the cryptocurrency industry. Photo courtesy of CryptoEQ

It's an interesting time for cryptocurrency and no one knows that better than Spencer Randall, principal and co-founder of Houston-based CryptoEQ, a company that's built a platform for resources and information for everyone interested in cryptocurrency and digital assets.

"CryptoEQ is really built to be the North Star for digital asset research and information. We provide market insights for both newcomers and folks that are already well-versed in cryptocurrency and digital assets," Randall says on this week's of the Houston Innovators Podcast. "The idea of the company is to help shepherd folks along and guide them on their crypto journey."

Recently the company entered into a partnership with The Cannon, an entrepreneurial hub with locations across Houston, to provide a one-of-a-kind crypto starter pack to help onboard innovators to the cryptosphere worldwide. Click here to read more and stream the episode.

Andy Grolnick, CEO of Graylog

A Houston company that's created a centralized log management solution has closed a new round in funding. Photo courtesy of Graylog

Houston-based Graylog closed its $18 million growth equity round led by new investors Harbert Growth Partners and Piper Sandler Merchant Banking, as well as existing investors Houston-based Mercury Fund and Integr8d Capital.

"This investment will enable us to accelerate our global go-to-market strategies and enhancements to the award-winning solutions we deliver for IT, DevOps, and Security teams," says Andy Grolnick, CEO of Graylog, in a press release. "We're excited to have the support of new and existing investor partners to help us realize our potential." Click here to read more.

Imran Alibhai, CEO at Tvardi

Tvardi Therapeutics Inc. has fresh funds to support its drug's advancement in clinical trials. Photo courtesy of Tvardi

Houston-based, cancer-fighting company Tvardi Therapeutics Inc. closed its $74 million series B funding round led by new investors New York-based Slate Path Capital, Florida-based Palkon Capital, Denver-based ArrowMark Partners, and New York-based 683 Capital, with continued support and participation by existing investors, including Houston-based Sporos Bioventures.

"We are thrilled to move out of stealth mode and partner with this lineup of long-term institutional investors," says Imran Alibhai, CEO at Tvardi. "With this financing we are positioned to advance the clinical development of our small molecule inhibitors of STAT3 into mid-stage trials as well as grow our team." Click here to read more.

Tvardi Therapeutics Inc. has fresh funds to support its drug's advancement in clinical trials. Photo via Getty Images

Cancer-fighting company based in Houston emerges from stealth and snags $74M in its latest round

fresh funds

A Houston-based clinical-stage biopharmaceutical company has raised millions in its latest round.

Tvardi Therapeutics Inc. closed its $74 million series B funding round led by new investors New York-based Slate Path Capital, Florida-based Palkon Capital, Denver-based ArrowMark Partners, and New York-based 683 Capital, with continued support and participation by existing investors, including Houston-based Sporos Bioventures.

"We are thrilled to move out of stealth mode and partner with this lineup of long-term institutional investors," says Imran Alibhai, CEO at Tvardi. "With this financing we are positioned to advance the clinical development of our small molecule inhibitors of STAT3 into mid-stage trials as well as grow our team."

Through Slate Path Capital's investment, Jamie McNab, partner at the firm, will join Tvardi's board of directors.

"Tvardi is the leader in the field of STAT3 biology and has compelling proof of concept clinical data," McNab says in the release. "I look forward to partnering with the management team to advance Tvardi's mission to develop a new class of breakthrough medicines for cancer, chronic inflammation, and fibrosis."

Tvardi's latest fundraise will go toward supporting the company's products in their mid-stage trials for cancer and fibrosis. According to the release, Tvardi's lead product, TTI-101, is being studied in a Phase 1 trial of patients with advanced solid tumors who have failed all lines of therapy. So far, the drug has been well-received and shown multiple durable radiographic objective responses in the cancer patients treated.

Dr. Keith Flaherty, who is a member of Tvardi's scientific advisory board and professor of medicine at Harvard Medical School, offered his support of the company.

"STAT3 is a compelling and validated target. Beyond its clinical activity, Tvardi's lead molecule, TTI-101, has demonstrated direct downregulation of STAT3 in patients," he says in the release. "As a physician, I am eager to see the potential of Tvardi's molecules in diseases of high unmet medical need where STAT3 is a key driver."

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Impact-driven Houston fintech startup emerges to streamline international remittance

money transfer tech

Africans living abroad send over $40 billion back to their home country annually — yet the process continues to be expensive, fraud-ridden, and complicated. A new Houston-area startup has a solution.

AiDEMONEY, based in Katy, has launched a money transfer app for mobile devices. The app enables digital transfers from the United States to five African countries: Cameroon, Ethiopia, Ghana, Kenya, and Nigeria

"International remittance has always been about people living in diaspora wanting to share their success with people back home," says Uzoma Eze, AiDEMONEY co-founder and CEO, in a news release. "By replacing profit as the point of the spear, we're helping Africans fund Africa and, ultimately, rewriting our motherland's story."

Eze co-founded the company with Felix Akompi, a fellow member of Houston's African diaspora community and the company's COO

The app, which is already available on the App Store and Google Play, focuses on blockchain-powered security and instant transfers. The company also designed the platform with a "give back" model that builds a stronger Africa.

With every transaction fee, users are funding progress in Africa. A portion of customer transaction fees to nonprofits in education and literacy, women's empowerment, and healthcare. Currently, AiDEMONEY partners with the Lagos Food Bank Initiative, Shalom Sickle Cell Foundation, Sharing Smiles Initiative, and Jenny Uzo Foundation.

"We're creating a superhighway for tens of billions in USD to flow from one part of the world to another," Eze says. "When you have the right people with the right vision, that capital tills the ground—tilling out profit, social advancement and a stronger Africa."

Doing Money Remittance Better | AiDEMONEY, The African Diaspora's Money Transfer App www.youtube.com

New Pearland healthcare training center will raise the bar for nursing in Houston

Training for More

As if those in the healthcare field needed another reason to relocate to Pearland: the HCA Healthcare Center for Clinical Advancement opened its doors on July 27.

Located at the Pearland Town Center at 11200 Broadway St., building 200, the two-story, 48,400-square-foot training center houses hospital simulation labs, virtually-connected classrooms, and debriefing rooms.

The center provides ongoing education for HCA Houston Healthcare's 7,000 nurses and will help standardize training across the system's 13 Greater Houston-area hospitals, outpatient surgery centers, emergency centers, and imaging facilities.

The utilization of simulcast technology will also facilitate education and training opportunities for colleagues working in locations across the HCA Healthcare Gulf Coast Division, which includes facilities in Corpus Christi and South Texas.

"The HCA Healthcare Center for Clinical Advancement is a significant part of our strategic nursing plan to support and grow our nurses as the differentiator at our hospitals and other facilities," says Kelli Nations, chief nurse executive at HCA Houston Healthcare, one of the city's largest healthcare systems. "It certainly helps us raise the bar for nursing care in Houston."

The first floor is designated for nurse training, which can last up to 22 weeks, depending on their specialty. Additional classroom and conference room space on the second floor will serve as a hub for new-hire orientations and the system's leadership and organizational development training for up to 250 employees at a time.

"Bringing the latest teaching technologies under one roof in a new, advanced facility is a major step in preparing our nurses to provide the highest level of care," says Nations.

Additional facility features include a simulated hospital supply room, a large break room, a mother's room for employees who are nursing, and several lounge areas.

Upcoming energy conference adds innovation focus for Houston-based event

innovating energy

The World Petroleum Congress, which plans to return to in-person status in December, is adding a new wrinkle — a pitch competition — to this year's event.

On August 4, the World Petroleum Congress announced the launch this year of the Innovation Zone, which will enable energy pioneers to showcase their offerings. The 2021 World Petroleum Congress — hosted in Houston this time around — is set for December 5-9 at the George R. Brown Convention Center.

Houston-based energy giant ConocoPhillips is sponsoring the Innovation Zone.

"For more than a century, innovation has enabled our industry to keep pace with the growing demand for safe and reliable energy," Bill Bullock, executive vice president and chief financial officer of ConocoPhillips, says in a news release. He adds that the Innovation Zone will highlight "innovations that can propel our industry's purposeful journey through the energy transition and into the future."

In all, 32 startups and individuals will pitch their products or practices on the World Petroleum Congress stage. One winner will be honored with the inaugural Energy Innovator Award.

The Innovation Zone is open to energy companies, private entities, and individuals working as independent contractors. Proposals will be evaluated on seven criteria:

  • Innovation
  • Creativity
  • Potential or actual technical or business success
  • Environmental impact
  • Stakeholder impact
  • Scalability
  • Broad-based uses

Applications for the Innovation Zone are due Aug. 20. To obtain an application, visit the World Petroleum Congress website. Representatives of ConocoPhillips and the World Petroleum Congress will sift through the applications and pick 32 finalists, who will be notified in early September.

"Startups, with their innovative business models, will play a decisive role in shaping a sustainable energy future, and for participating companies, this is a good opportunity to present and forge new links with key stakeholders and investors," says Serafina Lalany, interim executive director of entrepreneurship and innovation nonprofit Houston Exponential.

Aside from ConocoPhillips, sponsors of this year's World Petroleum Congress include Chevron, Halliburton, Accenture, Hess, ExxonMobil, BP, Qatar Petroleum, Baker Hughes, and Saudi Aramco.

The 23rd World Petroleum Congress was supposed to happen last year in Houston but was shifted to 2021 due to the COVID-19 pandemic. More than 10,000 people are expected to attend this year's event. It's been estimated that the World Petroleum Congress will pump $60 million to $80 million into the Houston economy.

Staged by the World Petroleum Council, the event hasn't been held in North America since 1987, when Houston hosted it. It's known as the "Olympics" of the oil and gas sector.

The 24th World Petroleum Congress will be held in 2023 in Calgary, Canada. The event traditionally takes place every three years.