Here's how AI-based chat will effect research. Graphic byMiguel Tovar/University of Houston

Researchers have to write extremely specific papers that require higher-order thinking — will an intuitive AI program like OpenAI’s ChatGPT be able to imitate the vocabulary, grammar and most importantly, content, that a scientist or researcher would want to publish? And should it be able to?

University of Houston’s Executive Director of the Research Integrity and Oversight (RIO) Office, Kirstin Holzschuh, puts it this way: “Scientists are out-of-the box thinkers – which is why they are so important to advancements in so many areas. ChatGPT, even with improved filters or as it continues to evolve, will never be able to replace the critical and creative thinking we need in these disciplines.”

“A toy, not a tool”

The Atlantic published, “ChatGPT Is Dumber Than You Think,” with a subtitle advising readers to “Treat it like a toy, not a tool.” The author, Ian Bogost, indulged in the already tired troupe of asking ChatGPT to write about “ChatGPT in the style of Ian Bogost.” The unimaginative but overall passable introduction to his article was proof that, “any responses it generates are likely to be shallow and lacking in depth and insight.”

Bogost expressed qualms similar to those of Ezra Klein, the podcaster behind, “A Skeptical Take on the AI Revolution.” Klein and his guest, NYU psychology and neural science professor Gary Marcus, mostly questioned the reliability and truthfulness of the chatbot. Marcus calls the synthesizing of its databases and the “original” text it produces nothing more than “cut and paste” and “pastiche.” The algorithm used by the program has been likened to auto-completion, as well.

However, practical use cases are increasingly emerging, which blur the lines between technological novelty and professional utility. Whether writing working programming code or spitting out a rough draft of an essay, ChatGPT does have a formidable array of competencies. Even if just how competent it is remains to be seen. All this means that as researchers look for efficiencies in their work, ChatGPT and other AI tools will become increasingly appealing as they mature.

Pseudo-science and reproducibility

The Big Idea reached out to experts across the country to determine what might be the most pressing problems and what might be potential successes for research now that ChatGPT is readily accessible.

Holzschuh, stated that there are potential uses, but also potential misuses of ChatGPT in research: “AI’s usefulness in compiling research proposals or manuscripts is currently limited by the strength of its ability to differentiate true science from pseudo-science. From where does the bot pull its conclusions – peer-reviewed journals or internet ‘science’ with no basis in reproducibility?” It’s “likely a combination of both,” she says. Without clear attribution, ChatGPT is problematic as an information source.

Camille Nebeker is the Director of Research Ethics at University of California, San Diego, and a professor who specializes in human research ethics applied to emerging technologies. Nebeker agrees that because there is no way of citing the original sources that the chatbot is trained on, researchers need to be cautious about accepting the results it produces. That said, ChatGPT could help to avoid self-plagiarism, which could be a benefit to researchers. “With any use of technologies in research, whether they be chatbots or social media platforms or wearable sensors, researchers need to be aware of both the benefits and risks.”

Nebeker’s research team at UC San Diego is conducting research to examine the ethical, legal and social implications of digital health research, including studies that are using machine learning and artificial intelligence to advance human health and wellbeing.

Co-authorship

The conventional wisdom in academia is “when in doubt, cite your source.” ChatGPT even provides some language authors can use when acknowledging their use of the tool in their work: “The author generated this text in part with GPT-3, OpenAI’s large-scale language-generation model. Upon generating draft language, the author reviewed, edited, and revised the language to their own liking and takes ultimate responsibility for the content of this publication.” A short catchall statement in your paper will likely not pass muster.

Even when being as transparent as possible about how AI might be used in the course of research or in development of a manuscript, the question of authorship is still fraught. Holden Thorp, editor-in-chief of the Science, writes in Nature, that “we would not allow AI to be listed as an author on a paper we published, and use of AI-generated text without proper citation could be considered plagiarism.” Thorp went on to say that a co-author of an experiment must both consent to being a co-author and take responsibility for a study. “It’s really that second part on which the idea of giving an AI tool co-authorship really hits a roadblock,” Thorp said.

Informed consent

On NBC News, Camille Nebeker stated that she was concerned there was no informed consent given by the participants of a study that evaluated the use of a ChatGPT to support responses given to people using Koko, a mental health wellness program. ChatGPT wrote responses either in whole or in part to the participants seeking advice. “Informed consent is incredibly important for traditional research,” she said. If the company is not receiving federal money for the research, there isn’t requirement to obtain informed consent. “[Consent] is a cornerstone of ethical practices, but when you don’t have the requirement to do that, people could be involved in research without their consent, and that may compromise public trust in research.”

Nebeker went on to say that study information that is conveyed to a prospective research participant via the informed consent process may be improved with ChatGPT. For instance, understanding complex study information could be a barrier to informed consent and make voluntary participation in research more challenging. Research projects involve high-level vocabulary and comprehension, but informed consent is not valid if the participant can’t understand the risks, etc. “There is readability software, but it only rates the grade-level of the narrative, it does not rewrite any text for you,” Nebeker said. She believes that one could input an informed consent communication into ChatGPT and ask for it to be rewritten at a sixth to eighth grade level (which is the range that Institutional Review Boards prefer.)

Can it be used equitably?

Faculty from the Stanford Accelerator for Learning, like Victor Lee, are already strategizing ways for intuitive AI to be used. Says Lee, “We need the use of this technology to be ethical, equitable, and accountable.”

Stanford’s approach will involve scheduling listening sessions and other opportunities to gather expertise directly from educators as to how to strike an effective balance between the use of these innovative technologies and its academic mission.

The Big Idea

Perhaps to sum it up best, Holzschuh concluded her take on the matter with this thought: “I believe we must proceed with significant caution in any but the most basic endeavors related to research proposals and manuscripts at this point until bot filters significantly mature.”

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This article originally appeared on the University of Houston's The Big Idea. Sarah Hill, the author of this piece, is the communications manager for the UH Division of Research.

Owning or even imagining that you own an object linked to a particular task can make you feel — and act — more like an adept. Photo via Getty Images

Houston research: Your tools can reflect your workplace skills

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Want to get better at a task? It may be possible to shop — or imagine — your way to success.

Just pretending to shop for items associated with certain skills (for example, a fancy calculator) may actually improve your performance in areas related to that skill (in this case, math).

That’s because our identities are highly influenced by our possessions — which we often experience as part of ourselves. As a result, this activation of an identity by our possessions, even imaginary ones, can enhance performance. For example, one study found that by using a pen labeled “MIT” on GRE exams, students scored higher than those using a standard Pilot pen, particularly when they believed that their inner ability was fixed, and that they had to rely on external products to improve their ability.

In 2018, Rice Business professor Jaeyeon Chung and Gita V. Johar of Columbia University took a close look at the implications of this human quirk.

In a series of experiments, Chung and Johar found that the product-related activation of our identities (e.g., calculator ownership awakening an inner math prodigy) can actually de-activate our identities unrelated to the product, and undermine performance in other tasks.

For example, shopping for a calculator could make you perform better on a math test, but worse on a creative-writing essay.

Merely owning an item, the scholars discovered, is only part of the equation. Self-concept clarity — that is, the strength and clarity of one’s personal beliefs — makes a difference as well. A person whose self-concept is well-defined, consistent, and stable is less likely to be influenced by external factors such as possessions.

To measure the phenomenon, Chung and her colleague devised a series of experiments. The results showed that when a person merely imagines an item she longs to own, two inner changes occur: Identities related to the product are awakened, and identities unrelated to the desired object are stifled. Strikingly, these changes have measurable consequences on the performance of tasks.

But how do you awaken an inner self through possession, and measure its effects? The team found an ingenious approach: They assigned people to a control group or an experimental group, and then asked them to peruse an online IKEA. The control group was told to shop for items to go in a senior citizen home. The experimental group shopped for items to go into their own homes.

The experimental group, who got to imagine items such as a MALM bed in their own bedrooms, were more likely to think of themselves as artistic designers than were their counterparts, the imaginary retirement home shoppers. The exercise, in other words, had activated participants’ art-related identities.

Next, Chung and Johar asked everyone to complete a math task. The experimental group scored lower at this than did those in the control group. Their newly awakened identities as design mavens had undermined their ability to solve math problems, apparently because they were unrelated to the fetching Scandinavian décor they’d imagined owning.

The researchers then took another approach. Asking one group of participants to imagine owning a calculator, they activated that group’s “math identity.” They then asked all the participants to engage in a short IQ test. Though there was only one test, the researchers labeled it two different ways, indicating to some participants that the test measured math skills, and to others that it measured creative writing skills.

Despite the test being exactly the same, the would-be calculator owners performed markedly worse when they thought they were doing a creative writing project than when they thought the test measured their math skills. Why, exactly? The researchers concluded that imagining owning a piece of math-y technology and activating their “math person identities” tamped down participants’ “creative writer” identities — so much so that it actually degraded their performance in that area.

In a third experiment, Chung and Johar asked a group to envision calculators that they actually owned, rather than simply imagining buying one. Again, the group that felt ownership regarding a math tool performed better on tasks that seemed math-related, but worse on tasks that seemed unrelated to math. The finding was robust when the task itself was exactly the same and the only difference how the task was labeled.

Interestingly, identity activation and performance were influenced by the participants’ level of self-concept clarity. Some people have a clear and consistent self-view that does not vary over time; these are individuals who are less likely to rely on their possessions or other environmental stimuli to infer who they are. These individuals were less likely to be affected by the “ownership” of a calculator.

In other words, self-concept clarity limited the power of ownership on identity activation and performance. Chung and Johar’s findings offer practical implications for both business and academia. Owning or even imagining that you own an object linked to a particular task can make you feel — and act — more like an adept.

So the next time you have a big quantitative test coming up, consider browsing for a high-end calculator first — and unwinding with your oil paints or “Infinite Jest” when you’re done. For best results, of course, take the test with your Rice-labeled pen.

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This article originally ran on Rice Business Wisdom and was based on research from Jaeyeon (Jae) Chung is an assistant professor of marketing at Jones Graduate School of Business at Rice University.

Earnings report delays generally lead to drops in stock prices. Disclosure can soften this market reaction. Photo via Getty Images

Houston research: Is no news always bad news in market reports?

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Investors eagerly wait for the news in their earnings reports. When these reports don't appear on the expected date, investors worry — and stock prices often fall as a result. But what if managers could present late reports in a way that spared their companies?

Research by K. Ramesh, a professor at Rice Business, shows that managers' approach to late earnings reports can profoundly affect market reaction. When firms put off filing a report, it's up to managers to decide whether to speak up or stay quiet. Those who choose to talk about a postponement then must decide how, what and how much to say.

All earnings delays, whether they're attended by a statement or not, prompt negative market reaction, prior research suggests. But in his research, Ramesh, Herbert S. Autrey Professor of Accounting, wanted to learn more about the exact consequences of these late reports, and how managers can lessen the blowback.

To do this, Ramesh and a team of coauthors first looked at the incidence, timing and contents of a comprehensive sample of press releases announcing an earnings delay. Then they studied what those delays did to market value.

Conventional wisdom in the business press already suggested that investors viewed any announcement of a delayed earnings report as bad news. But finance theorists tell a more complicated story, one in which the market response might be partially shaped by managerial behavior. Subtle factors, they found, such as whether the impending delay is discussed or treated with silence, really can make a difference.

In the view of some theorists, merely announcing a delay can sometimes avert a drop in stock prices. Others argue that this isn’t necessarily the case, especially if the company discloses that the delay stemmed from legal concerns. The better approach: making it clear up front that reports aren't being postponed to hide disastrous information. But what if the information is indeed disastrous?

That may be the one case where disclosure won’t change much, Ramesh and his team found.

“Those companies that are in fact concealing disastrous results will experience no benefits (in the form of higher stock price) from revealing their true situation,” the research team wrote, “because the market will infer the worst from the manager’s decision not to announce the delay.” For this reason, they added, delayed earnings without a stated explanation prompt the most negative market reaction. As in so many areas of public relations, without a narrative, investors will infer a negative one of their own.

To better understand the impact of late reports, Ramesh and his coauthors built a comprehensive sample of 545 delay announcements by using a keyword search of the Dow Jones Factiva database between January 1, 1995, and December 31, 2009.

As conventional wisdom suggested, the study showed that announcements of late earnings reports led to negative market reactions. (Earlier studies have shown smaller firms are hit hardest by this dynamic, perhaps because investors assume large companies have more finely tuned financial reporting systems, so are less worried by their earnings delays).

Consistent with the anecdotal evidence, the average one-day abnormal stock return for the sample was -6.29 percent, while the median return was -2.27 percent. Both figures are economically and statistically significant.

The researchers next classified the announcements according to stated reason, dividing the delays into “Accounting” and “Non-Accounting” categories. “Accounting” explanations were subdivided into “Accounting Issue,” “Accounting Process” and “Rule Change.”

Meanwhile, “Non-Accounting” explanations were divided into “Business,” which linked the delay to some event such as divestitures or regulatory proceedings, and “Other,” which ranged from earthquakes to power outages. Finally, there were delays for no stated reason at all.

About two-thirds of the late announcements, the team found, were linked to accounting. When firms named a specific accounting issue as the cause for delay, the average abnormal return reached a statistically significant -8.15 percent. When managers explained that the accounting process was not complete, the average abnormal return was slightly lower, at -7.04 percent.

After accounting issues, business events drove most earnings delays. In theory, these events could have been either good or bad news. But the average abnormal return for the subsample was a statistically significant -3.74 percent — a reflection of the fact that most business events linked to late earnings reports tend to be negative.

Curiously, the average abnormal return for the grouping classified as “Other” was almost nil — at 0.53 percent. This suggests that the market does not penalize managers for events outside of their control that have little, if any, relevance to firm performance.

“No Reason,” the researchers found, was the most damaging explanation of all. Seven percent of the sample, or 37 out of 545 delays, came without a stated reason. The average abnormal return for these was a significant -10.41 percent, a greater negative number than the returns for any of the other reasons.

So what should managers do when a deadline is going to be busted? Bite the bullet and disclose the reasons, Ramesh suggests. For one thing, it helps limit legal exposure and preserve credibility. When the reason for the late report is innocuous, explaining to investors can also mitigate the market's displeasure. A caveat: While informing investors that a power outage caused earnings delay will calm jitters, disclosure may not make a difference if the company just can’t balance its books.

It's human nature, apparently, to read no news as bad news. Relaying something—anything—about the cause of a late report seems to soothe investors' nerves by preventing them from filling the silence themselves.

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This article originally ran on Rice Business Wisdom and was based on research from K. Ramesh, Tiago Duarte-Silva, Huijing Fu and Christopher F. Noe. K. Ramesh is the Herbert S. Autrey Professor of Accounting at Jones Graduate School of Business at Rice University.

To err is human, after all. Graphic byMiguel Tovar/University of Houston

University of Houston: Navigating non-compliance and human error in research

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To comply is to obey, or conform to instruction or official requirements. In a perfect world, research non-compliance wouldn’t occur and following the rules would be a behavioral norm. But the reality is, to err is human.

To err is human

Often times the judgement of our own, and others, poor decision-making is rooted in the innate tendency to view things in black or white – categorizing behaviors as either right or wrong, good or bad, thus deeming them as either ethical or unethical.

But this way of thinking often conflicts with the gray world in which we exist. So what happens when research decisions land somewhere in the moral gray area?

Before answering, here are two situations to consider that involve the over-enrollment of research participants:

Case 1:
The IRB has approved a survey for 40 subjects. The PI realizes after the survey has been open for several weeks that she forgot to set a participant limit within the survey program and 60 subjects have completed the survey.

Case 2:

A study involving a new drug to control diabetes symptoms is approved to enroll 30 participants. The study doctor thinks the drug may be beneficial, so she continues enrolling, for a total of 80 subjects.

The devil is in the details

Why is over-enrollment of subjects considered non-compliance?

Many institutions have agreed, within their assurance to the U.S. Department of Health and Human Services (HHS), to apply the Common Rule to all human subjects research, whether the research is funded or not.

The Common Rule regulations found at 45 CFR 46.109(a) and 45 CFR 46.111 (1) state that the IRB shall review and have authority to approve, require modifications in (to secure approval), or disapprove all research activities. This includes the maximum number of research .

And what must the IRB review?

Under the above regulatory requirements, the IRB must evaluate all instances of non-compliance.

In these cases of over-enrollment, the IRB must review the number of subjects over-enrolled and assess any potential effects on additional subjects and/or the research, as well as determine if the noncompliant data may be used for research purposes.

What UH IRB says about Case 1:

While over-enrollment in a survey seems low-risk, depending on the content of the survey questions, the IRB could determine the issue to be more serious, such as for a study collecting data related to illegal substance use or questions about traumatic events (legal or psychological harm). The IRB must ensure that risks to subjects are minimized; only the number of subjects needed to statistically justify the research are approved. Depending on the number of subjects over-enrolled and the time period over which they participated, the non-compliance could also be considered continuing.

What UH IRB says about Case 2:

Investigational drug studies often pose more than minimal risk of harm to subjects. In these studies, it is even more critical to ensure that additional subjects are not exposed to potential harms without scientific justification

In a drug study, the PI may not continue a study based on opinion; the reason a physician is blinded to treatment assignment in many drug studies is to avoid potential bias.

Finding non-compliance: What can you do?

If the number of subjects enrolled exceeds the number approved by the IRB, a finding of non-compliance is justified. The IRB will review the numbers, the Principal Investigator’s reasons for over-enrollment and assess what procedures were conducted in these subjects. Often over-enrollment is inadvertent, however the committee also has the ultimate authority to determine whether the data may be used for research purposes.

Corrective actions, such as continuing education of the PI and/or study team to ensure this issue does not occur again in the future, are often required. In the most serious cases, the IRB may suspend or terminate approval.

If the non-compliance rises to the level of being serious (harms or has the potential to harm subjects or others) and/or continuing in nature, it must be reported to federal oversight agencies such as the Health and Human Services Office for Human Research Protections (OHRP) and the FDA. These agencies ensure that the institution is monitoring for these activities and puts appropriate fixes in place.

The importance of intetrity

Non-compliant research can be due to inadvertent errors or deliberate acts of noncompliance. The results could be the same. Human subjects could be harmed. Funding and reputation at an institution conducting research could be negatively affected. In times of reduced federal funding for basic research, there are direct financial costs to the agencies when funds and resources are misused.

The responsibility of ensuring that research protocols are adhered to rests upon the shoulders of the researchers involved.

If you were a member on the IRB, what would you consider to be appropriate consequences for the PI in these situations?

It’s important to note that non-compliance, whether it’s a “little white lie/inadvertent error” or a deliberate violation of the approved protocol can undermine the integrity of both the research process and the academic research enterprise.

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This article originally appeared on the University of Houston's The Big Idea. Nitiya Spearman, the author of this post, is the internal communications coordinator for the UH Division of Research.

Managers can nurture creativity, even in workers who appear less creative, by building a supportive environment. Image via Pexels

Workplaces need to support and encourage creativity, according to Houston research

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Give a kid a toy car, a stuffed bear, or an armful of blocks, and she is off on an imaginative romp, staging epic battles, building palaces or creating new worlds.

Coaxing creativity from adults is more challenging. But if creativity in children develops their spirits, creativity in adults enriches productivity — especially at the office.

It’s simple math. Creativity is where ideas come from; ideas form the basis for innovation. In an increasingly competitive world economy, it’s innovation that allows businesses to survive and thrive. This makes creativity a prized commodity in the job market. For managers, cultivating creativity in their workforce is a crucial professional skill.

Identifying the best circumstances to make creativity bloom is one of the driving questions in a study by Rice Business Professor Jing Zhou and colleague Inga J. Hoever, a professor at the Barcelona School of Management in Spain.

To explore the mystery of creativity, the two scholars first reviewed the hefty body of research by organizational psychologists and management scholars who’ve studied innovation in employees and teams. Most early research in this field, published since 2000, focused on the creativity of the actor — the individual or the team — or else revolved around the work environment.

Current academic research takes a more holistic look. By studying the interaction between the character traits of the worker or the team, the leader or the supervisor, and the prevailing atmosphere at the workplace, researchers are unveiling new insights.

Studies show, for example, that the benefits of benevolent leadership expand when workers recognize creativity as an important component of their role. Not only that, creativity is highest in employees who experience high levels of both positive and negative moods and feel supported by their supervisors. Other research finds that leaders who empower their workers get a greater payback in creativity.

To explore these findings further, Zhou and Hoever developed a typology that sorts out research about workplace creativity based on interactions between the worker (which they call the “actor”) and the workplace (which they call “context”).

The best-case scenario is a positive actor in a positive context, a mix that is synergistic for creativity. Worst case: When a positive actor languishes in a negative context or, similarly, when a negative actor stews in a positive context. At the extreme end of possibility, a negative actor in a negative context is downright antagonistic to creativity, Zhou and Hoever found.

There’s one final type of employee-workplace interaction: the “configurational” experience, which includes factors that are neutral in shaping creativity, but, when combined with other factors, cause a kind of chemical reaction that boosts or blocks creativity.

Zhou’s research serves up some bad news and good news for managers. Choosing and hiring employees who are creative is not enough, it turns out. If your workplace is discouraging, creativity will wither in almost anyone. On the brighter side, cultivate a nurturing environment and creative tendrils may sprout even in the most no-nonsense workers. Best of all, good managers can build a nurturing greenhouse environment. Practically speaking, it means that companies can and should train supervisors to cultivate creativity in their management choices.

Plenty of research gaps remain, however. To fill them, Zhou has outlined an ambitious agenda for future research, including a close look at the impact of workplaces on collective creativity; exploring as-yet unidentified factors in workers and work settings that spark creative thinking; and seeking ways to vanquish the effects of unsupportive environments.

Making creativity happen at work, in other words, isn’t child’s play.

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This article originally ran on Rice Business Wisdom and was based on research from Jing Zhou, the Mary Gibbs Jones Professor of Management and Psychology in Organizational Behavior at the Jones Graduate School of Business of Rice University.

Detractors are suspicious of the anonymity that comes with blockchain technology. Supporters say it's exactly the point. Photo via David McBee/Pexels

Houston expert weighs in on the trustworthiness of cryptocurrency

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Interest in cryptocurrencies reignited during the pandemic, driven in part by trillions of dollars in stimulus money that left many investors with “free money” to put to work. And while bitcoin recently tumbled nearly 55 percent from its peak, it remains the most valuable crypto asset in the world, with a market capitalization of around $589 billion. Its investors argue that it’s still a safer bet than stocks during this period of economic upheaval.

A renewed interest in cryptocurrencies — digital currencies that rely on blockchain technology, in which transactions are verified and records maintained by a decentralized system that uses cryptography — is widespread. Large corporations like Tesla, Mass Mutual and KPMG Canada have announced plans to hold cryptocurrency assets in treasury or accept them as payment. Meanwhile, major financial institutions are offering customers more digital asset investment options. Twelve years after bitcoin’s birth, mainstream investors are honing in on the currency, too.

In the midst of this market fascination, a fundamental question still remains. What exactly is cryptocurrency, and why should we care? And what about other industry buzzwords, like blockchain, decentralized exchanges or non-fungible tokens (NFTs)? Are they all just fads that will fade away?

Some have called cryptocurrency a Ponzi scheme, a tool for illicit activities, or a short-term fascination that will be irrelevant in a few years. It’s an understandable mindset, since there’s no intrinsic value in cryptocurrencies — not unlike the U.S. dollar after it stopped being backed by gold in the 1970s. But it’s also a shortsighted one. Blockchain technology, which allows users to exchange information on a secure digital ledger, is extremely useful because it automates contractual arrangements through computer programming.

I’m a firm believer that cryptocurrencies and the blockchain technology that underpins them are here to stay, and understanding how this technology has transformed our environment, and how it will continue to evolve, is critical to succeeding in business.

First steps

Bitcoin took the first major steps towards a truly electronic cash system in 2008, in the midst of one of the worst financial collapses of all time. Governments worldwide were bailing out financial institutions that had been deemed “too big to fail.” Perceptions of economic inequality spurred movements such as Occupy Wall Street, which was fueled by a distrust in banks.

Bitcoin, on the other hand, wasn’t created by a trusted source — in fact, no one knows exactly who invented it. In a 2008 white paper, “Bitcoin: A Peer-to-Peer Electronic Cash System,” Satoshi Nakamoto — the pseudonymous individual presumed to have developed bitcoin — described the currency as a way to securely facilitate financial transactions between parties without having to involve a central intermediary. No longer would people have to put their trust in the large financial institutions that failed them during the financial crisis.

Detractors find the lack of a central authority with blockchain worrisome, but proponents say it’s exactly the point: You no longer have to trust the person or institution you’re dealing with. You only have to trust the algorithms that run the program — and presumably an algorithm will never run off with your money.

Instead, blockchain enables a cooperative of members to run the shared network ledger required to keep track of a currency’s credits and debits. No one can shut down the system so long as a group of computers anywhere in the world is able to connect to the internet and run bitcoin’s software.

Because of bitcoin, today we can uniquely own digital assets and transfer them with the certainty that people can’t spend the same cryptocurrency twice. The transactions that bitcoin-like applications make possible are registered in permanent and immutable digital records for all to see in a common ledger.

By enabling fast and easily verifiable transactions, blockchain technology is also streamlining business operations in banking, supply chains, sustainability, healthcare and even voting. Development in these sectors and others is continuing at an intense pace. Annual global funding of blockchain projects now runs in the billions of dollars. From 2020 to 2021 alone, it jumped from several billion to nearly $30 billion.

Second generation

Since bitcoin’s arrival, we’ve seen a second, more sophisticated generation of cryptocurrencies evolve, with Ethereum as their flagship. Ethereum has its own programming language, enabling users to write and automate self-executing smart contracts, allowing for the creation of tokens for a specific use. For example, imagine that when Uber was founded, it had created an Uber token, and only people who owned Uber tokens could use the rideshare service. Tokens currently power thousands of decentralized applications that give people more privacy and control in a variety of areas, such as internet browsing, financial services, gaming and data storage, among others.

Some critiques of cryptocurrency remain. One growing concern is that cryptocurrencies require a significant amount of energy to run their networks, leading to higher transaction costs, energy waste and limited scalability. Newer cryptocurrencies are attempting to find ways to verify transactions that require less energy.

Some people also worry about ongoing volatility in cryptocurrency markets. A third generation of cryptocurrencies has emerged to address this concern: so-called “stablecoins,” which are pegged to a government-issued currency, a commodity, assets, or basket of assets. For some, stablecoins are serving as an onramp into the world of crypto from the world of traditional finance.

Before a new technology becomes part of everyday life, we often see a long period of development, improvement and consumer adoption. Cryptocurrency and blockchain markets are still in this early development stage, but they’re also moving quickly into the mainstream. The total market capitalization of cryptocurrencies late last year briefly reached the $3 trillion mark, or roughly 15 percent of the U.S. GDP, and there’s been more than $100 billion locked into decentralized finance applications.

Large companies like IBM, Amazon and Bank of America are leading the way by tapping into blockchain technology in their daily business activities. It won’t be long until this market, previously characterized by speculation and wild volatility, will be transformed into a stable infrastructure framework. But companies need to get up to speed on the industry now. Those that commit to doing so will be the ones that thrive.


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This article originally ran on Rice Business Wisdom and was written by Manolo Sánchez, an adjunct professor of operations management at the Jones Graduate School of Business at Rice University.

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7 lessons from a Houston-based unicorn startup founder

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At a fireside chat at SXSW, a Houston founder pulled back the curtain on his entrepreneurial journey that's taken him from an idea of how to make the chemicals industry more sustainable to a company valued at over $2 billion.

Gaurab Chakrabarti, the CEO and co-founder of Solugen, joined the Greater Houston Partnership's Houston House at SXSW on Monday, March 13, for a discussion entitled, "Building a Tech Unicorn." In the conversation with Payal Patel, principal of Softeq Ventures, he share the trials and tribulations from the early days of founding Solugen. The company, which has raised over $600 million since its founding in 2016, has an innovative and carbon negative process of creating plant-derived substitutes for petroleum-based products.

The event, which quickly reached capacity with eager SXSW attendees, allowed Chakrabarti to instill advice on several topics — from early customer acquisition and navigating VC investing to finding the right city to grow in and setting up a strong company culture.

Here are seven pieces of startup advice from Chakrabarti's talk.

1. Don’t be near a black hole.

Chakrabarti began his discussion addressing the good luck he's had standing up Solugen. He's the first to admit that luck is an important element to his success, but he says, as a founder, you can set yourself up for luck in a handful of ways.

“You do make your own luck, but you have to be putting in the work to do it," Chakrabarti says, adding that it's not an easy thing to accomplish. “There are things you can be doing to increase your luck surface area."

One of the principals he notes on is not surrounding yourself with black holes. These are people who don't believe in your idea, or your ability to succeed, Chakrabarti explains, referencing a former dean who said he was wasting his talent on his idea for Solugen.

2. The co-founder dynamic is the most important thing.

Early on, Chakrabarti emphasizes how important having a strong co-founder relationship is, crediting Solugen's co-founder and CTO Sean Hunt for being his "intellectual ping-pong partner."

“If you have a co-founder, that is the thing that’s going to make or break your company,” he says. “It’s not your idea, and it’s not your execution — it’s your relationship with your co-founder.”

Hunt and Chakrabarti have been friends for 12 years, Chakrabarti says, and, that foundation and the fact that they've been passionate about their product since day one, has been integral for Solugen's success.

"We had a conviction that we were building something that could be impactful to the rest of the world," he says.

3. Confirm a market of customers early on.

Chakrabarti says that in the early days of starting his company, he didn't have a concept of startup accelerators or other ways to access funding — he just knew he had to get customers to create revenue as soon as possible.

He learned about the growing float spa industry, and how a huge cost for these businesses was peroxide that was used to sanitize the water in the floating pods. Chakrabarti and Hunt had created a small amount of what they were calling bioperoxide that they could sell at a cheaper cost to these spas and still pocket a profit.

“We ended up owning 80 percent of the float spa market,” Chakrabarti says. “That taught us that, ‘wow, there’s something here.”

While it was unglamourous work to call down Texas float spas, his efforts secured Solugen's first 100 or so customers and identified a path to profitability early on.

“Find your niche market that allows you to justify that your technology or product that has a customer basis,” Chakrabarti says on the lesson he learned through this process.

4. Find city-company fit.

While Chakrabarti has lived in Houston most of his life, the reason Solugen is headquartered in Houston is not due to loyalty of his hometown.

In fact, Chakrabarti shared a story of how a potential seed investor asked Chakrabarti and Hunt to move their company to the Bay Area, and the co-founders refused the offer and the investment.

“There’s no way our business could succeed in the Bay Area," Chakrabarti says. He and Hunt firmly believed this at the time — and still do.

“For our business, if you look at the density of chemical engineers, the density of our potential customers, and the density of people who know how to do enzyme engineering, Houston happened to be that perfect trifecta for us," he explains.

He argues that every company — software, hardware, etc. — has an opportunity to find their ideal city-company fit, something that's important to its success.

5. Prove your ability to execute.

When asked about pivots, Chakrabarti told a little-known story of how Solugen started a commercial cleaning brand. The product line was called Ode to Clean, and it was marketed as eco-friendly peroxide wipes. At the time, Solugen was just three employees, and the scrappy team was fulfilling orders and figuring out consumer marketing for the first time.

He says his network was laughing at the idea of Chakrabarti creating this direct-to-consumer cleaning product, and it was funny to him too, but the sales told another story.

At launch, they sold out $1 million of inventory in one week. But that wasn't it.

“Within three months, we got three acquisition offers," Chakrabarti says.

The move led to a brand acquisition of the product line, with the acquirer being the nation's largest cleaning wipe provider. It meant three years of predictable revenue that de-risked the business for new investors — which were now knocking on Solugen's door with their own investment term sheets.

“It told the market more about us as a company,” he says. “It taught the market that Solugen is a company that is going to survive no matter what. … And we’re a team that can execute.”

What started as a silly idea led to Solugen being one step closer to accomplishing its long-term goals.

“That pivot was one of the most important pivots in the company’s history that accelerated our company’s trajectory by four or five years," Chakrabarti says.

6. Adopt and maintain a miso-management style.

There's one lesson Chakrabarti says he learned the hard way, and that was how to manage his company's growing team. He shares that he "let go of the reins a bit" at the company's $400-$500 million point. He says that, while there's this idea that successful business leaders can hire the best talent that allows them to step back from the day-to-day responsibilities, that was not the right move for him.

“Only founders really understand the pain points of the business," Chakrabarti says. "Because it’s emotionally tied to you, you actually feel it."

Rather than a micro or macro-management style, Chakrabarti's describes his leadership as meso-management — something in between.

The only difference, Chakrabarti says, is how he manages his board. For that group, he micromanages to ensure that they are doing what's best for his vision for Solugen.

7. Your culture should be polarizing.

Chakrabarti wrapped up his story on talking about hiring and setting up a company culture for Solugen. The company's atmosphere is not for everyone, he explains.

“If you’re not polarizing some people, it’s not a culture,” Chakrabarti says, encouraging founders to create a culture that's not one size fits all.

He says he was attracted to early employees who got mad at the same things he did — that passion is what makes his team different from others.

Houston tech company to acquire IT infrastructure startup

M&A moves

Hewlett Packard Enterprise has announced its plans to acquire a San Jose, California-based startup.

HPE, which relocated its headquarters to Houston from the Bay Area a couple years ago, has agreed to acquire OpsRamp, a software-as-a-service company with an IT operations management, or ITOM, platform that can monitor, automate, and manage IT infrastructure, cloud resources, and more.

According to a news release from HPE, the OpsRamp platform will be merged with the HPE GreenLake edge-to-cloud platform, which supports more than 65,000 customers, powers over two million connected devices, and manages more than one exabyte of data with customers worldwide.

The new integrated system "will reduce the operational complexity of multi-vendor and multi-cloud IT environments that are in the public cloud, colocations, and on-premises," per the statement.

“Customers today are managing several different cloud environments, with different IT operational models and tools, which dramatically increases the cost and complexity of digital operations management,” says HPE's CTO Fidelma Russo in the release. “The combination of OpsRamp and HPE will remove these barriers by providing customers with an integrated edge-to-cloud platform that can more effectively manage and transform multi-vendor and multi-cloud IT estates.

"This acquisition advances HPE hybrid cloud leadership and expands the reach of the HPE GreenLake platform into IT Operations Management,” she continues.

HPE's corporate venture arm, Pathfinder, invested in OpsRamp in 2020. The company raised $57.5 million prior to the acquisition. Other investors included Morgan Stanley Expansion Capital and Sapphire Ventures, per TechCrunch.

“The integration of OpsRamp’s hybrid digital operations management solution with the HPE GreenLake platform will provide an unmatched offering for organizations seeking to innovate and thrive in a complex, multi-cloud world. Partners and the channel will also play a pivotal role to advance their as-a-service offerings, as enterprises look for a unified approach to better manage their operations from the edge to the cloud,” says Varma Kunaparaju, CEO of OpsRamp, in the release.

“We look forward to leveraging the scale and reach of HPE’s global go-to-market engine to deliver our unique offering and are excited for this journey ahead as part of HPE.”

3 Houston innovators to know this week

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from space tech to software development — recently making headlines in Houston innovation.


Michael Suffredini, CEO and president of Axiom Space

Axiom's CEO announced a new mission and space suit design. Photo courtesy of Axiom Space

It was a big news week for Axiom Space. The Houston company announced its next commercial space mission with NASA to the International Space Station a day before it unveiled its newly design space suit that will be donned by the astronauts headed to the moon.

“We’re carrying on NASA’s legacy by designing an advanced spacesuit that will allow astronauts to operate safely and effectively on the Moon,” says Micahel Suffredini, CEO of Axiom, in a statement. “Axiom Space’s Artemis III spacesuit will be ready to meet the complex challenges of the lunar south pole and help grow our understanding of the Moon in order to enable a long-term presence there.”

Called the Axiom Extravehicular Mobility Unit, or AxEMU, the prototype was revealed at Space Center Houston’s Moon 2 Mars Festival on March 15. According to Axiom, a full fleet of training spacesuits will be delivered to NASA by late this summer. Read more.

Julie King, president of NB Realty Partners

Houston's access to lab space continues to be a challenge for biotech companies. Photo via Getty Images

In terms of Houston developing as an attractive hub for biotech companies, Julie King says the city still has one major obstacle: Available lab space.

She writes in a guest column for InnovationMap that biotech startups need specialized space that can hold the right equipment. That's not cheap, and it's usually a challenge for newer companies to incur that cost.

"However, with realistic expectations about these challenges, the good news is that once settled into a facility that is a fit, Houston’s emerging biotech companies can thrive and grow," she writes. Read more.

Owen Goode, executive vice president at Zaelot

Houston software development firm Axon is planning its Texas expansion thanks to its recent acquisition. Photo via LinkedIn

Owen Goode is a huge fan of Houston. That's why when his software design firm, Axon, got acquired by Zaelot, led by CEO Jeff Lombard, in January, he made sure the deal would mean growth in the region.

Zaelot is a global, software firm with a presence in 14 countries, mostly focused in the United States, Uruguay, and Iceland. With the acquisition of Axon, the combined company is poised to expand in Texas, beginning in Houston, Goode says.

“Together we have a strong suite of offerings across a wide variety of domains including full-stack development, cloud/data engineering, design, staff augmentation, project management, and software architecture. We also have experience in multiple domains, including health care, aviation, defense, finance, and startups,” says Goode. Read more.