MassChallenge names 10 Houston companies to national cohort

class of 2022

MassChallenge has selected 10 Houston startups to participate in its 2022 United States cohort. Photo courtesy of MassChallenge 

Ten Houston companies have been chosen for MassChallenge’s 2022 United States cohort of early-stage startups.

The 10 Houston startups are:

  • BEMY Cosmetics, a maker of skin rejuvenation products based on RNA technology
  • Eisana Corp., whose products are designed to ease the side effects of breast cancer treatment
  • Enrichly, a self-esteem-based e-learning platform and gaming app
  • RE.STATEMENT, an online marketplace for upcycled clothing
  • Roxie Health, a virtual medical assigned geared toward preventing falls by seniors
  • Vivifi Medical, whose laparoscopic technology treats male infertility and prostate gland enlargement
  • Vouchpad, a provider of affordable student loans
  • Equiliberty, an equitable fintech platform focused on creating generational wealth
  • National Police Data, an organization creating an index of Police data in America
  • Cryodesalination, a new low cost desalination process focused on providing access to fresh water

In all, the MassChallenge innovation network selected 250 early-stage startups for this fall’s U.S. accelerator program in Houston, Austin, Dallas, Boston, and Providence, Rhode Island. Participants are eligible for equity-free cash prizes of as much as $1 million. MassChallenge is open to early-stage startups that have raised less than $1 million in equity funding and have generated less than $2 million in revenue over the past 12 months.

“We’re in the business of solving massive challenges, and to do that, we must continue to support diverse founders with bold ideas across geographies, industry verticals, and demographics in creative ways that allow them to wholly own their ideas and solve some of our world’s most pressing problems,” Hope Hopkins, head of acceleration at MassChallenge, says in a news release.

This year’s cohort will have access to MassChallenge’s new residency program, which allows founder teams to travel to MassChallenge’s U.S.-based hubs. The residency program already is underway in Houston and Boston.

In addition, founders will be able to take advantage of a newly created program that enables them to connect with MassChallenge stakeholders.

Last year, MassChallenge named 71 startups to its Houston cohort, and several walked away from the program with cash prizes. Per the nonprofit's website, there isn't a Houston-specific program planned for 2022. MassChallenge has had a presence in Houston since January of 2019 when it announced the Bayou City as a new market.

Note: This article originally identified seven Houston startups. The article has been updated to include the three Houston startups initially omitted.

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Houston startup funding surpasses $1B in 2025 despite national slowdown

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Houston-area startups raised more than $1 billion in venture capital during the first half of 2025 — almost double the haul for the first half of last year.

According to the new PitchBook-NCVA Venture Monitor, Houston-area startups raised $417.2 million in the second quarter of this year, compared with $281 million during the same period last year. In the first quarter of 2025, local startups collected $607.5 million in venture capital, compared with $281 million during the same period a year earlier.

Based on those figures, Houston-area startups picked up slightly over $1 billion in VC during the first half of this year, compared with $535 million in the first half of 2024.

Nationally, startups gained almost $70 billion in VC in the second quarter, down 25 percent from the same period a year ago, the PitchBook-NCVA Venture Monitor says.

Nizar Tarhuni, executive vice president of research and market intelligence at PitchBook, explained that “the VC landscape continues to navigate a fragile recovery” and is constrained by economic uncertainty.

However, startups in certain sectors are poised to attract a great deal of attention and venture capital over the next several years, according to the report.

“Companies operating in AI, national security, defense tech, fintech, and crypto — sectors aligned with the administration’s priorities — are attracting disproportionately more investor interest, and this trend will likely continue throughout President Donald Trump’s term,” the report says.

The AI sector accounted for 64 percent of VC deal value in the first half of 2025, according to the report.

2 Houston universities among world's best and more innovation news to know

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Editor's note: We're looking back at the biggest Houston business and innovation news from the first half of July. From the world's best universities to innovative cybersecurity staffing, catch up on the top InnovationMap stories from July 1-15 below:

2 Houston universities declared among world’s best in 2026 rankings

Rice is the No. 2 best school in Texas, and No. 119 in the world. Photo via Rice University

Two Houston universities are in a class of their own, earning top spots on a new global ranking of the world's best universities.

Rice University and University of Houston are among the top 1,200 schools included in the QS World University Rankings 2026. Ten more schools across Texas make the list. Continue reading.

Texas cybersecurity co. expands unique train-to-hire model to Houston

San Antonio-based Nukudo is bridging the global cybersecurity talent gap through immersive training and job placement in Houston. Photo via Getty Images

It’s increasingly more difficult to ensure the confidentiality, integrity, and availability of proprietary data and information in the ever-changing, ever-evolving digital world. Cyberattacks, including malware, phishing, and ransomware, are becoming increasingly common and sophisticated, posing a consistent threat to a company’s sustainability and bottom line.

To combat that trend, Nukudo, a San Antonio-based cybersecurity workforce development company, is expanding its initiative to bridge the global cybersecurity talent gap through immersive training and job placement to Houston. Continue reading.

Houston hospital performs first fully robotic heart transplant in the U.S.

Dr. Kenneth Liao and a team at Baylor St. Luke’s Medical Center used a surgical robot to implant a new heart in a 45-year-old male patient. Photo courtesy Baylor College of Medicine.

A team at Baylor St. Luke’s Medical Center, led by Dr. Kenneth Liao, successfully performed the first fully robotic heart transplant in the United States earlier this year, the Houston hospital recently shared.

Liao, a professor and chief of cardiothoracic transplantation and circulatory support at Baylor College of Medicine and chief of cardiothoracic transplantation and mechanical circulatory support at Baylor St. Luke’s Medical Center, used a surgical robot to implant a new heart in a 45-year-old male patient through preperitoneal space in the abdomen by making small incisions. Continue reading.

New Houston biotech co. developing capsules for hard-to-treat tumors

Sentinel BioTherapeutics is developing cytokine interleukin-2 (IL-2) capsules to fight many solid tumors. Photo via Getty Images.

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Sentinel CEO Rima Chakrabarti says. Continue reading.

Greentown Labs names Lawson Gow as its new Houston leader

Lawson Gow, founder of The Cannon, will lead Greentown Houston. Photo courtesy Greentown Labs.

Greentown Labs has named Lawson Gow as its Head of Houston.

Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role. Continue reading.

Houston space companies land $150M NASA contract for vehicles and robots

space simulations

Houston-based MacLean Engineering and Applied Technology Services LLC, known as METECS, has received a five-year contract from NASA to develop simulations and software services for space-based vehicles and robots, with a maximum value of $150 million.

Two other Houston-area companies, Tietronix Software Inc. and Vedo Systems LLC, were assigned as subcontractors for the award.

"This award is a strong testament to NASA’s continued trust in the quality of our work and their confidence in our ongoing support of the human spaceflight program," John MacLean, president of METECS said in a release.

According to NASA, the awardees are tasked with providing:

  • Simulation and software services for space-based vehicle models and robotic manipulator systems
  • Human biomechanical representations for analysis and development of countermeasure devices
  • Guidance, navigation, and control of space-based vehicles for all flight phases
  • Space-based vehicle on-board computer systems simulations of flight software systems
  • Astronomical object surface interaction simulation of space-based vehicles
  • Graphics support for simulation visualization and engineering analysis
  • Ground-based and onboarding systems to support human-in-the-loop training

The contract is called Simulations and Advanced Software Services II (SASS II), and begins in October. This is the second time METECS has received the SASS award. The first also ran for five years and launched in 2020, according to USASpending.gov.

METECS specializes in simulation, software, robotics and systems analysis. It has previously supported NASA programs, including Orion, EHP, HLS, Lunar Gateway and Artemis. It also serves the energy, agriculture, education and construction sectors.

Tietronix Software has won numerous awards from NASA. Most recently, it won the NASA JSC Exceptional Software Award (2017). Some of its other customers include Houston Independent School District, Baylor College of Medicine, DARPA and Houston Methodist.

Video Systems offers software for implementing human-rated, AI and autonomous systems, as well as engineering services to address the needs of spaceflight and defense. The company has previously worked with NASA and METECS, as well as Axiom Space and defense contractor Lockheed Martin.

The three companies are headquartered near NASA’s Johnson Space Center in Houston.

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