Real estate giant taps downtown Houston tower for new smart building tech

hi, tech

Tenants of this downtown office building just got an upgrade. Rendering via 717texas.com

Houston-based real estate giant Hines is rolling out a new smart building platform with the goal of better serving workers and workplaces at its buildings across the country, including one building in Houston that's aiming to be an office building of the future.

From the employee perspective, the new Hines app will allow employees and employers to book spaces within buildings, order food from on-site cafes and restaurants, book on-site fitness classes and access the building via their smartphone or smartwatch. For employers and tenants, the app will help them gain insights into building performance, occupancy data, ESG targets and employee satisfaction, according to a statement from Hines.

“We’re committed to a people-centric experience and this investment takes that commitment to the next level,” Ilene Goldfine, chief digital strategy officer at Hines, says in a statement. “The traditional systems were managed building by building and made it difficult or impossible to track performance across a portfolio. This new digital ecosystem, which unites back-end technology with front-end experiences, will deliver long-term cost savings to our investors and clients.

"Our clients will also be able to track employee satisfaction, make informed decisions about their space needs and ensure they’re monitoring their carbon targets,” Goldfine continues.

The new digital platform will be launched at eight Hines buildings across five cities, including 717 Texas Ave., a 33-story Class A office tower in Downtown Houston.

The other buildings where Hines will roll out the app include:

  • Salesforce Tower in Chicago
  • 1144 15th Street in Denver
  • The Kearns Building in Salt Lake City
  • CIBC Square in Toronto
  • T3 Bayside in Toronto
  • Two buildings at T3 Sterling Road in Toronto

The company plans to add more locations across its global portfolio.

Hines' opened its first location of The Square coworking space at 717 Texas Ave. in 2020 as part of its coworking concept Hines². The company, in collaboration with Montreal-based Ivanhoé Cambridge, opened a second Houston location of The Square recently and has a coworking space in The Kearns Building in Salt Lake City where it will roll out the new app.

Earlier this year, Hines also launched a sustainability-focused business unit, known as EXP by Hines. The unit, led by Hines veteran Doug Holte, aims to address “the disruptive changes in the built environment.”
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Hines, which has its global HQ in downtown Houston, has established an ESG-focused initiative. Photo via hines.com

Houston-based real estate giant rolls out sustainability-focused business unit

seeing green

Houston-based real estate investor, developer, and manager Hines is stepping up its commitment to sustainability.

The company just formed a business unit, EXP by Hines, that is aimed at addressing “the disruptive changes in the built environment.”

EXP by Hines comprises two parts: Global ESG and the Global Venture Lab. Doug Holte, who was a senior partner at Hines from 1987 to 2009, has been hired as CEO of EXP.

“EXP by Hines is an engine of growth using the most innovative ideas in capital, culture, and environmental stewardship to connect every stakeholder in the built environment and create healthy, activated communities,” Holte says in a news release. “EXP is looking beyond the boundaries of real estate to solve complex problems while creating long-term value.”

Peter Epping, who joined Hines in 2001, is the company’s global head of ESG (environmental, social, and governance). A 2022 survey by professional services firm Deloitte found that ESG continues to gain ground in the corporate world. Business executives questioned for the survey believe ESG strategies will:

  • Strengthen stakeholder trust
  • Elevate brand reputation
  • Boost employee retention
  • Improve ROI
  • Reduce risk

Kathryn Scheckel, who joined Hines in 2019, leads the company’s new Global Venture Lab, which is tasked with identifying and accelerating ventures, partnerships and investments. The lab includes a startup incubator and a VC arm.

According to the news release, priorities of the Global Venture Lab include innovations in the use of physical space, development of ESG solutions, and creation of “revolutionary built-world technologies.”

The efforts being spearheaded by Holte, Epping, and Scheckel are geared in part toward Hines achieving net zero carbon by 2040 in its nearly 231 million-square-foot global portfolio without buying carbon credits.

This week's roundup of Houston innovators includes Zimri Hinshaw of BUCHA BIO, Kelly Klein of Easter Seals of Greater Houston, ad John Mooz of Hines. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from esports to biomaterials — recently making headlines in Houston innovation.

Zimri Hinshaw, CEO of BUCHA BIO

Zimri T. Hinshaw, CEO of BUCHA BIO, joins the Houston Innovators Podcast to discuss how he's planning to scale his biomaterials startup to reduce plastic waste. Photo courtesy of BUCHA BIO

After raising a seed round of funding, BUCHA BIO is gearing up to move into its new facility. The biomaterials company was founded in New York City in 2020, but CEO Zimri T. Hinshaw shares how he started looking for a new headquarters for the company — one that was more affordable, had a solid talent pool, and offered a better quality of life for employees. He narrowed it down from over 20 cities to two — San Diego and Houston — before ultimately deciding on the Bayou City.

Since officially relocating, Hinshaw says he's fully committed to the city's innovation ecosystem. BUCHA BIO has a presence at the University of Houston, Greentown Labs, and the East End Maker Hub — where the startup is building out a new space to fit the growing team.

"By the end of this month, our laboratories will be up and running, we'll have office space adjacent, as well as chemical storage," Hinshaw says on the Houston Innovators Podcast. Listen to the episode and read more.

Kelly Klein, development director of Easter Seals Greater Houston

A nonprofit organization has rolled out an esports platform and event to raise awareness and funding for those with disabilities. Photo via Easter Seals

For many video games is getaway from reality, but for those with disabilities — thanks to a nonprofit organization —gaming can mean a lot more. On Saturday Dec. 3 — International Day of Persons with Disabilities — from 1 to 9 pm, Easter Seals Greater Houston will be joining forces with ES Gaming for the inaugural Game4Access Streamathon.

Gaming helps enhance cognitive skills, motor skills, improve mental well-being, and can help reduce feelings of social isolation due to the interactive nature of playing with others.

“This is really a unique way for (people) to form a community without having to leave their house, and being part of an inclusive environment,” says Kelly Klein, development director of Easter Seals Greater Houston. ”The adaptive equipment and specialized technology just does so many miraculous things for people with disabilities on so many levels — not just gaming. With gaming, it is an entrance into a whole new world.” Read more.

John Mooz, senior managing director at Hines

Levit Green has announced its latest to-be tenant. Photo courtesy

Levit Green, a 53-acre mixed-use life science district next to the Texas Medical Center and expected to deliver this year, has leased approximately 10,000 square feet of commercial lab and office space to Sino Biological Inc. The Bejing-based company is an international reagent supplier and service provider. Houston-based real estate investor, development, and property manager Hines announced the new lease in partnership with 2ML Real Estate Interests and Harrison Street.

“Levit Green was meticulously designed to provide best-in-class life science space that can accommodate a multitude of uses. Welcoming Sino Biological is a testament to the market need for sophisticated, flexible space that allows diversified firms to perform a variety of research,” says John Mooz, senior managing director at Hines, in a press release. “Sino is an excellent addition to the district’s growing life science ecosystem, and we look forward to supporting their continued growth and success.” Read more.Read more.

Levit Green has announced its latest to-be tenant. Rendering courtesy

Rising Houston life science district signs health tech tenant​

growing on the green

A rising life science hub has signed its latest tenant.

Levit Green, a 53-acre mixed-use life science district next to the Texas Medical Center and expected to deliver this year, has leased approximately 10,000 square feet of commercial lab and office space to Sino Biological Inc. The Bejing-based company is an international reagent supplier and service provider. Houston-based real estate investor, development, and property manager Hines announced the new lease in partnership with 2ML Real Estate Interests and Harrison Street.

“Levit Green was meticulously designed to provide best-in-class life science space that can accommodate a multitude of uses. Welcoming Sino Biological is a testament to the market need for sophisticated, flexible space that allows diversified firms to perform a variety of research,” says John Mooz, senior managing director at Hines, in a press release. “Sino is an excellent addition to the district’s growing life science ecosystem, and we look forward to supporting their continued growth and success.”

With a global presence, Sino Biological is a leading provider of mammalian cell-based recombinant proteins, antibodies, and related contract research services, per the release, and the recently announced location represents the company’s first US-based manufacturing facility.

“We are extremely excited about our new partnership with the Hines team and our forthcoming laboratories and production facilities at Levit Green. Hines is at the forefront of next-generation laboratory space design and development, and our new site at the Levit Green master-planned district in the heart of Houston’s Texas Medical Center will enable Sino Biological to considerably expand its research services and bioreagent manufacture capabilities into the United States,” says Dr. Rob Burgess, chief business officer for Sino Biological, in the release.

Sino's space will be in Building I at Levit Green — a 290,000-square-foot, five-story building with wet lab and incubator space — and is expected to be ready for move-in by the third quarter of 2023. The facility is the first to deliver in the nine-building Levit Green masterplan, which includes office and research space, as well as retail, residential, and more. According to the release, the building will also feature amenities — a 5,800-square-foot fitness center and outdoor garden, a 7,000-square-foot conference center, 3,500 square feet of café and restaurant space, and on-site parking.

Levit Green was first announced in the summer of 2020.

Hines, which opened its Texas Tower in 2021, is hoping to reach net-zero operational carbon by 2040. Image via Hines

Houston real estate giant cracks down on carbon emissions

seeing green

Houston-based real estate giant Hines is on a mission to make its entire global portfolio free of carbon emissions.

Hines recently set a target of its 1,530 properties in 28 countries being net-zero operational carbon by 2040, including the 27.7 million square feet of space it owns or manages in the Houston area. Operational carbon refers to greenhouse gases produced by building operations.

The company says it will accomplish the net-zero goal by reducing emissions through renewable technology, and not by purchasing carbon offset credits.

Peter Epping, global head of ESG (environmental, social, and governance) at Hines, says that because the company has made its carbon-neutral plan public, “investors, developers, engineers, and building managers across our industry can use it to guide their own carbon-reduction efforts.”

Hines notes that the real estate sector emits nearly 40 percent of global carbon emissions related to energy. The World Building Council’s Net Zero Carbon Buildings Commitment calls for decarbonizing half of buildings by 2030 and all buildings by 2050.

“As the impact of climate change is becoming increasingly integrated into our lives every day, the real estate industry has a responsibility to acknowledge this growing problem and take meaningful action to reduce our collective carbon emissions,” Jeff Hines, chairman and co-CEO of Hines, says in a news release. “By seeking to achieve net-zero operational carbon without relying on offsets, Hines wants to raise the bar for sustainability and invest in a plan designed to achieve significant and tangible results.”

To achieve those results, Hines plans to:

  • Halting the use fossil fuels to power buildings in its $90.3 billion portfolio.
  • Reducing energy demand by improving building efficiencies.
  • Boosting reliance on renewable energy.
  • Using “circular systems” to reduce energy waste and enhance efficiency.
  • Promoting carbon capture.

A recent report from Houston-based law firm Vinson & Elkins underscores the economic benefits that the net-zero movement presents to commercial real estate players like Hines.

“Real estate increasingly attracts attention from sustainability-minded investors amid a wider push for ESG considerations in bond and loan markets. … Decarbonizing the real estate industry will likely require trillions of dollars of capital, but there is vast opportunity for environmentally friendly projects to access additional financing sources, often on favorable terms,” Caitlin Snelson, sustainable finance senior associate in the Houston office of Vinson & Elkins, says in a news release.

Beyond real estate, Hines’ net-zero campaign aligns with efforts to transform Houston into a net-zero industrial hub. A whitepaper published by Columbia University’s Center on Global Energy Policy declares that Houston is well-positioned to become a “best in class” net-zero hub.

According to the whitepaper, the hub “could serve as a magnet for new and emerging industries, innovators and entrepreneurs and investment in energy transition companies and resources. Failure to develop a hub could lead to loss of these benefits and opportunities.”

Consulting giant McKinsey & Co. points out that clean hydrogen is emerging as a vehicle to achieve net-zero status and says Houston could evolve into a global hub for clean hydrogen. A Houston hub that’s in place by 2050 could generate 180,000 jobs and an economic impact of $100 billion, according to McKinsey.

“With the right supportive policy frameworks, Texas could become the global leader in clean-hydrogen production, application, development, and exports with Houston at its core; the resulting thriving hydrogen community could push innovation and develop the necessary talent to conceive and deliver hydrogen projects,” McKinsey says.

Laura Hines-Pierce, 38, is the new co-CEO with her father Jeff Hines. Photo courtesy of Hines

Gerald D. Hines' granddaughter named new co-CEO of global real estate powerhouse

boss up

A global real estate juggernaut now has a new — and familiar — face in the executive office. Hines announced that Laura Hines-Pierce has been promoted to co-CEO, joining Jeff Hines, her father.

This move makes Hines-Pierce, 38, one of the youngest CEOs of a major real estate organization and one of only a few women in an often male-dominated industry.

Hines-Pierce was most recently Hines’ senior managing director in the office of the CEO since 2020, and before that, served as the firm’s transformation officer. She is credited with building the investment management platform that launched three flagship funds across the U.S. and Asia with a total current investment capacity of $4.8 billion in equity, translating to $10.8 billion in purchasing power.

Other work included integrated innovation into all areas of the business and further defined the firm’s ESG commitments, per press materials.

While serving as the firm’s transformation officer, Hines-Pierce worked with the co-heads of investment management, the global chief investment officer, and the CEO of capital markets, to refine investment strategy and acquisition efforts.

On-the-ground and grassroots work also included serving as project manager for River Point, a one-million-square-foot development in Chicago. She was also part of the OneHines Women’s Network, which focused on the company’s diversity and inclusion.

Before her Hines tenure, Hines-Pierce worked for Sotheby’s in New York. She graduated from Duke University with a BA in Economics and Art History and received her MBA from Harvard University, per her bio.

As far as next steps, Hines is keeping it in the family: plans include Hines-Pierce’s two brothers, Adam and Matthew Hines, who are expected to join her and Jeff in the office of the CEO.

“I’m proud to become co-CEO and continue the momentum we’re experiencing across the board at Hines,” said Hines-Pierce in a statement. “My father has been the catalyst for our global expansion and growth over the past three decades and I’m excited to partner with him at this pivotal moment for the firm. The pace of innovation in real estate is finally catching up with other industries; my primary focus has always been – and continues to be – positioning Hines at the forefront of those changes.”

Hines is the brainchild of real estate icon Gerald D. Hines, who passed away in 2020 at the age of 95. Gerald Hines engineered his fledgling firm from an entrepreneurial startup in Houston in 1957 into an international powerhouse that has developed, owned, and managed some of the world’s most recognizable architectural landmarks across five continents. The firm boasts nearly 1,500 buildings in 255 cities in 27 countries and some $84 billion in assets.

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This article originally ran on CultureMap.

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Meet 6 mentors guiding Houston’s next generation of startup founders

meet the finalists

Houston’s thriving startup ecosystem is supported by a network of experienced leaders who work behind the scenes, investing their time and knowledge to help the next generation of entrepreneurs succeed.

As part of the 2026 Houston Innovation Awards, the Mentor of the Year category will honor an individual who dedicates their time and expertise to guide and support budding entrepreneurs. They support promising startups in the medical tech, digital health, clean energy, hardware sectors and more.

Read more about these businesses, their founders and their breakthrough technologies below. The 2026 winners will be announced on InnovationMap.com in mid-November.

Al Danto, Rice University

Al Danto is a senior lecturer in entrepreneurship at Rice University. He mentors undergraduate and graduate students at Rice and through the university's Liu Idea Lab for Innovation and Entrepreneurship (Lillie). He's also involved in the Houston Entrepreneurs Organization and Rice Veterans' Business Battle.

"[Mentoring] is very rewarding and fulfilling," Danto says. "[It] helps to me to pay back full circle over the incredible mentors I have had."

Eric Rubenstein, New Climate Ventures

Eric Rubenstein is managing partner at New Climate Ventures. He mentors startups through the clean energy-focused early-stage VC firm and also through the Breakthrough Energy Fellowship, Activate, Greentown Labs and Yale Ventures. Rubenstein has worked with numerous startups and Innovation Awards finalists, including Solidec, Rheom Materials, Bairitone Health, Pattern Materials and many others.

"Being a mentor is an important part of an innovation ecosystem," Rubenstein says. "Seeing founders succeed is rewarding, particularly if what they are building will meaningfully contribute to society. It is a way to give back that also builds community, as mentorship often involves introducing founders to other mentors, to potential investors and to potential customers. Just like the adage 'it takes a village' is used in reference to raising a child, the same adage applies to building a startup. That’s why we say 'let’s build.' Let’s build is inclusive because we do it together, as a community, even if the founders need to execute on a daily basis to make their vision a reality."

Jeremy Pitts, Activate

Jeremy Pitts serves as managing director of Activate Houston, which launched in Houston in 2024. He was one of the founders of Greentown Labs in the Boston area and served in a leadership role for the organization between 2011 and 2015. Through Activate, he has mentored numerous impactful startups and Innovation Awards finalists, including Solidec, Coflux Purification, Bairitone Health, Newfound Materials, Deep Anchor Solutions and others.

"Mentorship to me is all about selflessly supporting a person," Pitts says. "The person comes first--if you're not supporting the person, then their business needs don't matter. I'm there not to answer questions for people, but to help them gain the confidence and the capability to solve problems on their own. I am successful when my mentees are successful and happy, regardless of what their personal definition of success might look like."

Joe Alapat, Liongard

Joe Alapat founded and serves as chief strategy officer at Houston software company Liongard. He founded Startup Circle Houston and co-hosts Cybersecurity Circle, which both meet regularly at The Ion. He participates in Mercury Fund Day and has also mentored through Impact Hub Houston. He's worked with founders of FlowCare, Unytag, STEAM OnDemand, Lokum and many other early-stage startups.

"I compare being a mentor for startup founders to the Montessori method. ... Mentoring should not involve telling a founder what to do," Alapat says. "I see it as a founder whisperer approach that seeks to challenge the founder to think through their journey through different lenses and go on a journey of self-discovery while discovering the true market pain they are seeking to solve. The cherry on top is that the mentor gains as much as the mentee, so learning is happening for both. Ultimately, the meter of achievement with mentoring is seeing visible progress with the maturity of the founder and the degree of traction for their startup."

Kyle Judah, Rice University's Liu Idea Lab for Innovation & Entrepreneurship

Kyle Judah is the executive director of Lilie, where he mentors pre-seed student startups. He also mentors through organizations like TEX-E, Greentown Labs, Activate and previously with MassChallenge. Some of the startups he's mentored include Helix Earth Technologies, Tierra Climate, Solidec, HexaSpec, SteerBio and many others.

"[Being a mentor] means helping to ensure that the most people possible have the best shot possible at making their company a successful reality," Judah says. "It means, at its root, opening the aperture for what is possible for people, by believing in them before anyone else even understands what their ambitions are. Because belief is the most infectious thing in the world. And before digging into the work in the trenches, most times founders need to kickstart their journey by having someone from the outside believe in them, when there's no real evidence to support that belief. So I guess, mentorship is a pure form of entrepreneurial faith."

Rachel Bickham, Bickham Services Unlimited LLC

Rachel Bickham is CEO of Bickham Services Unlimited, through which she mentors founders across a range of business stages and industries. She founded the organization in 2017. Bickham also mentors through The Affirmed Entrepreneur, a mentorship platform that she also launched. In 2024, she also began mentoring through the Goldman Sachs One Million Black Women: Black in Business program. Some of the startups she has worked with included Elaine Transportation, Nakira's World and NP Skills Made Easy, among others.

"Being a mentor means helping someone see what is possible while being honest about what it will take to get there," Bickham says. "It is not about giving generic advice or telling entrepreneurs what they want to hear. Sometimes mentorship means offering encouragement, and sometimes it means asking difficult questions that help someone avoid an expensive mistake. In both situations, my responsibility is to listen, share what I have learned, and help the entrepreneur make an informed decision. ... Being a mentor also means opening doors when I can—making introductions, inviting entrepreneurs into rooms they may not have entered on their own, and helping them build relationships that can change the direction of their businesses. It also means holding them accountable for what they said they wanted to accomplish. I do not measure successful mentorship by how often someone returns to me for an answer. I measure it by whether they become more confident, more strategic, and better equipped to make decisions on their own."

3 Houston incubators and accelerators fueling the growth of local startups

Meet the finalists

It takes a village to launch a business. That's where Houston's network of incubators and accelerators can step in, providing the resources, mentorship and community needed to push a fledgling company forward.

As part of our 2026 Houston Innovation Awards, the Incubator/Accelerator of the Year category honors a local organization that is championing and fueling the growth of Houston startups.

Three incubators and accelerators have been named finalists for the 2026 award. They support startups ranging from hard-tech companies to food and youth concepts.

Read more about these organizations below. The 2026 winners will be announced on InnovationMap.com in mid-November.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced in 2024, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its third Houston cohort this summer.

The two-year program graduated its first class of Houston fellows in 2026 and saw its first alumni IPO from Houston-based Fervo Energy, which previously participated in a Berkley cohort. Nationally, it has supported 346 fellows and 276 companies since 2015. Those companies have raised more than $6 billion in follow-on funding, according to Activate. In Houston, it has supported Houston startups like Solidec, FlowCellutions and Orbital Arc. Activate Houston is led by managing director Jeremy Pitts, who co-founded Greentown Labs in Boston. It is based out of the Ion.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with members spanning 72 countries. Launched in 2018, Impact Hub Houston says its membership tripled by the beginning of 2026. This year brought major milestones for the community, including the launch of its Ideas to Impact Accelerator, which supported 11 founders across the health, education, food systems, civic technology and workforce development sectors. It also received funding from more than 20 international Impact Hubs to develop SYNC, a collaboration platform that 25 Impact Hubs across five continents have committed to pilot. The organization has worked with local startups including Myoviva Health, The Change Lab and INNERVERSE Inc.

MarMo Innovation

Galveston-based business incubator MarMo Innovation is focused on removing barriers to entrepreneurship. It aims to provide affordable space, education, mentorship, market access, connections and real-world opportunities that help entrepreneurs move from idea to launch to sustainable growth. The "industry-agnostic" incubator was founded in 2022 and is led by Executive Director Erica Delgadillo.

This year, the organization moved from primarily serving as a coworking and community space into a more comprehensive entrepreneurial incubator by expanding its MarMo Market, MarMo Market Jr. and Lunch LineUp programs. A major focus for MarMo is food entrepreneurship. It is developing an Incubator Kitchen, which MarMo says will support programs like its Cottage to Commercial Bootcamp and Food Biz 101. The organization also expanded its board this year and says it is diversifying its revenue through memberships, events, markets, equipment and space rentals, sponsorships, grants and new entrepreneurial programming.

Baylor College of Medicine launches VC fund to invest in biotech startups

fresh funding

Houston’s Baylor College of Medicine just unveiled a new venture capital fund that backs early-stage biotech startups—and it’s already made its first investment.

BCM Legacy Fund I, funded by philanthropies, invested an undisclosed amount in Houston biotech startup Nemea Therapeutics. Nemea, a spinout of the Baylor College of Medicine and Germany’s Lead Discovery Center, is developing an oral drug to treat metastatic triple-negative breast cancer that no longer responds to currently available therapies.

This type of aggressive cancer spreads from the breast to other areas of the body, such as the bones, liver, lungs or brain. Roughly 38,000 to 57,000 Americans are diagnosed each year with metastatic triple-negative breast cancer. One study showed about half of patients survive past the one-year mark following diagnosis and about one-third survive two years.

“Baylor College of Medicine’s laboratories produce discoveries with the potential to change patients’ lives, and too many of them stall where academic funding ends and private investment has not yet begun,” Dr. Jakub Tolar, president, CEO and executive dean of the Baylor College of Medicine, said in a press release. “The BCM Legacy Fund fills that gap, giving our scientists a path to advance their discoveries to patients.”

The National Institutes of Health awards more than $36 billion per year for biomedical research in the U.S., Baylor said. But some biomedical discoveries “never leave the starting line because they don’t yet fit the economics of venture capital,” the college said.

“The forefront of a new model”

The BCM Legacy Fund aggregates philanthropic capital from private foundations and donor-advised funds. It then invests in startups so they can move beyond that starting line and into later-stage investment rounds. The Greater Houston Community Foundation is the fund’s philanthropic partner.

“It’s exciting to be on the forefront of a new model for philanthropic capital,” said Houston entrepreneur and investor Burton Hanson, managing partner of the fund.

“Not only do we hope to solve a real problem by advancing these therapies to the patients who need them most, but we also hope this model will inspire others in the city and beyond toward philanthropic creativity and a posture of ‘I sacrifice; we win.’”

The fund expects to invest in about 15 early-stage startups over a five-year span. Baylor declined to divulge the amount of money in the fund and the size of the investment in Nemea.

Nemea’s “world-class chemistry”

Hanson oversees the Baylor fund alongside Chicago investor Steve Lehmann, who led the University of Chicago’s Innovation Fund.

Lehmann said Nemea, the fund’s first portfolio company, “has world-class chemistry, Baylor biology, and patients with no good options. Our job is to fund the experiments that carry it to the next handoff, so that industry and later-stage investors can take it from there.”

Based at Houston’s massive Texas Medical Center, Nemea plans to start clinical trials next year in collaboration with Baylor’s Lester and Sue Smith Breast Center.

Nemea previously received $9 million from the Lead Discovery Center and a $1.6 million grant from Baylor. Last year, the startup said it was seeking $25 million to $30 million in seed and Series A funding.

Debra McCoy of Houston, a former managing director at BlackRock and former partner at Bain & Co., and Paul Thomas, co-founder and CEO of Spring-based benefits manager Luscinia Health, sit on the Baylor fund’s governing board. Dr. Paul Klotman, former president, CEO and executive dean of Baylor, is a senior strategic adviser.

How does the fund find investment targets?

The Baylor Legacy Fund relies on two tools to help unearth early-stage biotech startups:

  • High-resolution “innovation maps” of research institutions. These maps surface hidden clusters of innovation, identify rising-star researchers and tie pockets of “innovation supply” at Baylor to areas of “innovation demand” in biotech.
  • AI-enhanced due diligence. AI agents assist with due diligence of early-stage biotech startups. The fund says the platform “distills the frameworks we’ve developed over a decade of teaching and investing into a flexible … diligence environment.”
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