From a free workspace competition at The Cannon to a tech company's big acquisition, here are some Houston innovation short stories. Courtesy of The Cannon

It's easy to miss some of Houston's innovation news — there's quite a lot coming out across town. From contests launching out of The Cannon to a Houston tech company making a major acquisition, here are some quick news stories you need to know.

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Onit Inc.makes acquisition

Houston-based contract management software company, Onit Inc., announced the acquisition of SimpleLegal, another legal services software company. The terms of the deal were not made public.

"Onit and SimpleLegal share both a passion for both disrupting the legal technology space and valuing product innovation," says Eric M. Elfman, Onit CEO and co-founder, in a release. "Our shared commitment to elevate legal operations technology is an asset for all of our customers – from rapidly growing startups with their first in-house counsel all the way to the largest, most complex organizations. Together, our goal is to help all legal operations professionals achieve operational excellence on their legal technology journey."

According to the release, all product, support and services will go on without any interruption for customers of both companies. Elfman will serve as the CEO of the merged organization, and Nathan Wenzel, who was the CEO and co-founder of SimpleLegal, has been named the general manager of SimpleLegal.

"Today, corporations spend more than $160 billion on their in-house legal teams. The combination of Onit and SimpleLegal is a game-changer for the legal market and the future of legal operations," says Wenzel in the release. "Our teams are uniquely equipped to help shape the technology that is powering legal departments worldwide. Together, we're looking forward to combining efforts and talent to build and bring to market the next generation of legal operations technology."

The Cannon and Insperity launch startup competition

The Cannon's 120,000-square-foot space is on track to open this summer. Courtesy of The Cannon

The Insperity Innovation Scholarship is back — this time the prize of 6 months of free office space inside The Cannon means the new, 120,000-square-foot space that's set to open in West Houston very soon.

"We are so excited that Insperity has chosen to bring back this year's Innovation Scholarship and will be rewarding another lucky Houston area startup with space in our brand new building," says The Cannon's founder and CEO, Lawson Gow, in a release. "As one of our original partners, we are looking forward to another year of working with Insperity to fulfill a mission that we share — providing Houston area startups with all the resources they need to succeed and establish Houston as an exceptional place to start your business." (Gow is the son of InnovationMap's CEO.)

The applications are open from now until June 5. The finalists will be notified on June 7. All of the finalists will pitch their company to a panel of judges on June 13. Companies based in the Houston area with 3 to 8 employees are eligible. Startups can apply here.

New-to-Houston coworking concept in CITYCENTRE breaks ground

FUSE Dynamic Workspace just announced its new 26,000-square-foot project coming to CITYCENTRE. Photo via workfuse.com

The construction process has officially started this month for Texas-based FUSE Dynamic Workspace's second location in CITYCENTRE. The complex will consist of 26,000 square feet of coworking space in two buildings connected by a bridge, and include an additional 5,000 square feet across four outdoor terraces. The space will have 95 private offices, a coworking café and lounge, dedicated desks, and conference space for up to 100 people.

FUSE strives to provide business professional amenities while also giving back to its community. The first location was in Prosper, Texas.

re:3D wins over $700,000 grant

After just opening a new factory and community space, re:3D was awarded a large grant. Courtesy of re:3D

Houston-based re:3D, which just opened its new 7,000-square-foot community space and factory, recently won a six-figure grant from the National Science Foundation.

The SBIR Phase II grant is for $749,111 to further commercialize the company's Gigabot and increase maker manufacturing through 3D printing with reclaimed plastic and direct drive pellet extrusion, according to an email sent to re:3D's community.

Griddy grows with new partnership

Griddy Energy enables customer pricing transparency. Photo via gogriddy.com

Griddy Energy has signed a strategic partnership with EDF Trading Ltd — a subsidiary of low-carbon energy group EDF Group. Through this partnership, EDF will provide support to Griddy as it expands its services.

"We're thrilled to announce this deal because our focus has always been saving Texans money by connecting them directly to the grid for wholesale electricity rates. This partnership means we can bring the power of wholesale to far more people," Greg Craig, CEO of Griddy, says in a release, "In 2018, Texans paid a combined $20 billion to REPs. Had Texans paid wholesale last year, they would have paid just $14 billion. That means Texans overpaid by a staggering $6 billion last year. Our goal is to get as much of that money back into the hands of Texans in the form of savings — and this partnership with EDF will allow us to do just that."

Griddy, which has a huge presence in Texas, provides customers wholesale electricity prices and promises to be open, honest, and transparent. Rather than charging inflated rates, the company only makes a profit from the $9.99 monthly membership fees. Everything else is at cost — no margins, hidden fees, or break fees. Read more about Griddy here.

LetsLaunch and The Cannon team up ahead of a live fundraising event

LetsLaunch, a Houston-based fundraising platform, has teamed up with The Cannon. Courtesy of LetsLaunch

Fundraising for your company could be stressful, but exciting. Now, imaging that process taking place at an event in a face-to-face capacity. LetsLaunch and The Cannon have teamed up to put on a live fundraising event — think of it like a online fundraising platform meets a cocktail party.

The event is set for June 15, and LetsLaunch is taking applications for potential participating startups until May 24. Apply here. 

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Microsoft partners with Rice University's OpenStax on AI teaching tool

group project

Rice University’s OpenStax and Microsoft are partnering to integrate the nonprofit’s content with the tech giant’s AI innovation, known as Learning Zone.

“At OpenStax, our mission is to make an amazing education accessible to all,” Richard G. Baraniuk, founder and director of OpenStax, said in a news release. “That’s why we’re excited to integrate our trustworthy, peer-reviewed content with Microsoft’s AI technology through the Microsoft Learning Zone. Together, we aim to help more instructors and their students access engaging, effective learning experiences in new and dynamic ways. We also share a strong commitment to the thoughtful and responsible application of AI to better ensure all learners can succeed.”

OpenStax is a provider of affordable instructional technologies and is also one of the world’s largest publishers of open educational resources (OER).

Microsoft Learning Zone promises to provide educators and students with “responsible AI technology and peer-reviewed educational content to support learning” on Microsoft Copilot+ PCs. Microsoft Learning Zone works by utilizing on-device AI to generate interactive lessons for students, and its integration with OpenStax content means educators can rely on OpenStax’s digital library of 80 openly licensed titles.

The goal is for educators to create effective and engaging learning experiences safely, thereby bypassing the need to source and vet content independently. Included is a library of ready-to-use lessons, opportunity for immediate feedback and differentiated learning. Educators will maintain control of instructional content and pedagogical strategies and will be able to update or edit lessons or activities prior to sharing them with students.

Other tools included in the Microsoft Learning Zone are additional languages, reading coaching, public speaking help, math and reading progress, and a partnership with the online quiz platform Kahoot!

OpenStax resources have been reported as used across 153 countries, and this current collaboration combines the power and potential of responsible AI usage in education with content that has been utilized by 13,569 K-12 schools and 71 percent of U.S. colleges and universities, according to Rice.

“Through our partnership with OpenStax, we’re combining the power of on-device AI in Copilot+ PCs with OpenStax’s trusted and diverse peer-reviewed content to help educators quickly create high-quality, personalized, engaging lessons,” Deirdre Quarnstrom, vice president of Microsoft Education, added in the news release. “We’re excited about how this collaboration will empower classrooms globally.”

Houston ranks among the 15 best cities in America for 2025

Ranking It

A new national report ranking the best cities in America has declared Houston is the 13th best U.S. city in 2025.

The annual "America's Best Cities" report from Resonance Consultancy, a Canada-based real estate and tourism marketing firm, ranks the relative qualities of livability, cultural "lovability," and economic prosperity in America's principal cities with metropolitan populations of 500,000 or more.

These top 100 cities "brilliantly weave local culture with economic prospects, aligning with global and domestic travel trends to create premier experiences for both residents and travelers."

Houston's new placement is three spots lower than its triumphant No. 10 rank in 2024. Though it no longer holds a prized top-10 spot, the report hails Houston as a "coveted hometown for the best and brightest on earth."

Among Houston's other shining attributes are its booming population growth – which has now grown to a staggering 7.51 million people – plus its competitive real estate market and a vibrant hospitality and culinary scene. Additionally, Houston earned a well-deserved No. 4 rank in the report's "restaurants" subcategory.

"A 221-room Home2 Suites/Tru by Hilton debuted near Toyota Center in March, while Marriott’s newly renovated Residence Inn NASA/Clear Lake keeps surging visitors happy," the report said. "West Houston’s Greenside will convert 35,000 square feet of warehouses into a park-laced retail hub by 2026, while America’s inaugural Ismaili Center, rising along Allen Parkway, remains on schedule for later this year, adding yet another cultural jewel to H-Town’s festival-fueled mosaic."

The report additionally puts a large focus on Houston's innovative energy sector and its numerous large companies that boost the local economy and create thousands of jobs. Several of these Houston-based companies are some of the best places to work, according to U.S. News and World Report.

One such company that was specifically praised in the report was the HyVelocity Hub, which aims to "ensure economic resilience and long-lasting, domestic energy production" along the Gulf Coast.

"The HyVelocity Hydrogen Hub just locked in up to $1.2 billion from the U.S. DOE, targeting 45,000 jobs and slicing 7.7 million tons of CO₂ a year," the report said.

Elsewhere in Texas

Dallas (No. 14) and Austin (No. 15) ranked right behind Houston in the top 20, while San Antonio sank into the No. 41 spot after previously ranking 32nd last year. El Paso also fell from No. 83 in 2024 to No. 100 this year.

Jason McGrath, the executive vice president and head of U.S. Corporate Reputation at Ipsos, said in the report that American cities are proving their resiliency as they are faced with "climate issues, increasing infrastructural demands, and shifting geopolitical landscapes affecting international relations and travel."

"Despite these hurdles, cities are creatively reinventing themselves to shine as examples of cultural vibrancy and innovation, keeping their competitive edge both locally and globally," McGrath said. "Our report shows that the allure of American cities remains strong, thanks to their rich diversity and vast attractions — from natural wonders to buzzing cultural hubs."

The top 10 best cities in America in 2025 are:

  • No. 1 – New York City, New York
  • No. 2 – Los Angeles, California
  • No. 3 – Chicago, Illinois
  • No. 4 – San Francisco, California
  • No. 5 – Seattle, Washington
  • No. 6 – Miami, Florida
  • No. 7 – Boston, Massachusetts
  • No. 8 – Washington, D.C.
  • No. 9 – Las Vegas, Nevada
  • No. 10 – San Diego, California
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This article originally appeared on CultureMap.com.

Houston biosciences company opens new sequencing center for drug development

bioscience breakthroughs

Houston-based Avance Biosciences has launched the Next-Generation Sequencing Center of Excellence, designed to enhance the company’s sequencing capabilities for drug development. Specifically, the facility at the company’s main campus in Northwest Houston will pursue breakthroughs in biologics, cell therapy and gene therapy.

In the drug industry, sequencing refers to studying nucleotides in DNA and RNA molecules. Nucleotides are the building blocks of DNA and RNA.

“This is a major milestone for Avance Biosciences as we continue to support the evolving needs of biologics and cell and gene therapy developers,” Xuening “James” Huang, co-founder, CEO and chief technology officer of Avance, said in a news release. “By consolidating state-of-the-art sequencing platforms and scientific talent, we’ve created a highly capable organization ready to solve complex genomic challenges with precision and compliance.”

In 2013, Avance rolled out next-generation sequencing (NGS) that complies with federal guidelines. Since then, Avance “has remained at the forefront of regulated sequencing services,” the company said. “The launch of the (new center) strengthens the company’s ability to deliver accurate, reproducible, and regulatory-aligned sequencing data across a wide array of therapeutic modalities.”

Cal Froberg, senior vice president of sales and marketing at Avance, said pharmaceutical and biotech clients trust the company’s technical capabilities and regulatory compliance.

“With the ever-changing global landscape and increasing scrutiny around international sample shipments, conducting advanced, cost-effective NGS testing domestically is now more feasible than ever,” Froberg said. “Our clients have confidence that their samples will remain in the U.S.”

Avance, founded in 2010, plans to hold an open house at the new facility in September to showcase its capabilities, technology, talent, and services. The company’s services include sequencing, molecular biology, cell-based testing, and bioanalytical testing.