6 female-founded startups shaping the Houston innovation ecosystem

meet the finalists

Meagan Pitcher, CEO of Houston-based Bairitone Health. Photo courtesy of LinkedIn

Female-founded businesses reached a new milestone last year. According to payroll company Gusto, female founders launched 49 percent of new businesses in 2024, reaching near parity with male-founded businesses for the first time.

And though they still face challenges, with access to VC funding at the top of the list, those women-led companies are driving major impact in the startup and innovation ecosystem.

The fifth-annual Houston Innovation Awards will honor six women-led startups that are shaping Houston innovation in our Female-founded Businesses category, presented by Houston Powder Coaters.

The finalists for the 2025 award, selected by our esteemed panel of judges, range from a company developing natural carbon-free fuel to another launching at-home sleep apnea technology.

Read more about these innovative startups and the visionary female founders behind them below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled at our live awards ceremony.

Tickets are now on sale for this exclusive event celebrating all things Houston innovation.

Anning Corporation

Clean energy company Anning Corporation is working to develop geologic hydrogen, a natural carbon-free fuel, using its proprietary stimulation approaches and advanced exploration modeling. The company said that geologic hydrogen has the potential to be the lowest-cost source of reliable baseload electricity in the U.S.

The company was founded by CEO Sophie Broun in 2024 and is a member of Greentown Labs. Last month, it also announced that it was chosen to participate in Breakthrough Energy’s prestigious Fellows Program. Anning raised a pre-seed round this year and is currently raising a $6 million seed round.

Bairitone Health

Bairitone Health is bringing anatomy imaging for sleep apnea to the home environment. The company's platform maps users' anatomy during natural sleep using a facial patch to determine the root cause of airway obstruction. It then offers effective therapies for each patient. The system is currently in the research and development phase and is being used in clinical trials and studies.

The company was founded in 2022 in the Texas Medical Center's Biodesign program by CEO Meagan Pitcher, CTO Onur Kilic and chief medical officer Britt Cross. It was a member of Activate Houston's inaugural cohort and has participated in numerous accelerators and incubators. It raised a pre-seed round last year of $435,000.

Brain Haven

Founded at the University of Houston, Brain Haven is developing neuroscience-based, clinically validated protocols that use sensory stimulation through smell and sound to offer a natural and non-invasive way to activate the brain and preserve neuroplasticity. The company aims to deliver an accessible and affordable way for the aging population to preserve memory, delay cognitive decline and improve quality of life.

The company was co-founded by Gail Aflalo, a graduate student in the University of Houston College of Optometry, and Jokūbas Žiburkus, an associate professor in the department of biology and biochemistry at UH. It was selected to participate in the 2024 Innov8 Cohort, where it won the cohort's Startup Pitch Day, and was included in Class 13 of UH RED Labs. Brain Haven was awarded $70,000 in seed funding from UH in June 2025 to support a year-long research initiative in adults aged 50 and above.

FlowCare

Sugar Land-based FlowCare is developing a period health platform that integrates smart dispensers, education and healthcare into one system to make free, high-quality organic period products more accessible.

The company was founded by CEO Tanu Jain, a registered nurse and product management executive, in 2024. It participated in the TiE Women Program and the Houston Community College Business Plan Competition, placing in the top five in both pitch competitions.

March Biosciences

Houston cell therapy company March Biosciences aims to treat unaddressed challenging cancers, with its MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma, currently in Phase 2 clinical trials.

The company was founded in 2021 by CEO Sarah Hein, Max Mamonkin and Malcolm Brenner and was born out of the TMC Accelerator for Cancer Therapeutics. The company completed a $29.6 million series A last year and also raised a $4.2 million seed round.

TrialClinIQ

Houston-based TrialClinIQ is an AI-powered clinical trial recruitment platform that helps identify, qualify and enroll eligible patients in appropriate trials faster and more accurately.

The company was founded in 2025 by CEO Jontel Pierce and Janette Obi.

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

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Denise Hamilton, founder and CEO of WatchHerWork, is publishing a book that helps guide Black Lives Matter allies to make changes that will help them change the world. Photo courtesy of WatchHerWork

Houston entrepreneur tackles diversity and inclusion challenges through new book

HOUSTON INNOVATORS PODCAST EPISODE 39

If you went to school in America, you might have been taught that George Washington's teeth were made out of wood. While this information might have been effective in promoting oral health as a kid, it's important for you to know that George Washington's dentures were not made of wood. They were made of ivory, metal alloys, and other human teeth — usually pulled from slaves.

History seems to have been rewritten in this case, and it's not the first — nor the last — time that's happened. Denise Hamilton wants individuals to recognize moments, acknowledge them, and move forward toward the truth. That's why she's publishing a thoughtful journal entitled "Do Something: An Ally's Guide to Changing Yourself So You Can Change Your World."

"I feel really strongly that we all have these challenging stories in our minds that we have to identify and release," Hamilton shares on this week's episode of the Houston Innovators Podcast. "I give that example so that we all are clear that we don't have the full story for a lot of these topics. To me, if you allow yourself to be humble and be open to the fact that you really cannot believe everything you think, we can make so much progress in this space."

Hamilton founded her company, WatchHerWork, five years ago to act as a platform for women seeking career advice and mentorship.

"I had been an executive for many years — around 25 years at this point — and I had been the only woman or the only African American in so many situations that people wanted to pick my brain or take me to lunch," she says. "Frankly, there weren't enough hours in the day."

The company evolved to more, and now she's focused on diversity and inclusion consulting and leadership.

In the months following the death of George Floyd, Hamilton has seen companies react in various ways to the resurgence of the Black Lives Matter movement with marketing campaigns and initiatives for improving workplace conditions.

"The biggest challenge is the same thing that's the biggest opportunity," she says. "Every company has the opportunity to reinvent their approach to how they handle systemic racism in their organizations, and they are terrified by it."

As Hamilton has seen first hand, companies are navigating a minefield of how to react. In her consulting with companies, Hamilton has advised business leaders to be transparent and recognize if they haven't been an ally in this space — and to not act like it. Disclose the things that are being improved and amplify the work that's already been done — don't reinvent the wheel, she says.

"And if you turn this moment into a marketing event instead of a true seed change, we can spot that a mile away. Lead with authenticity, be sincere, and be honest," she says.

The other ongoing challenge Hamilton is navigating with her work is the effect COVID-19 has had on women in the workplace. The pandemic has amplified existing gender issues in the workplace and created new challenges as well. In the past, female executives have been able to climb the corporate ladder while hiring services to help on the home front, but COVID-19 pulled the rug out from under these women's feet.

"Women are starting to opt out because they are overwhelmed," Hamilton says, adding that this thought terrifies her. "We shouldn't live in a society that penalizes you for having children — that's just the bottom line."

What employers have to realize — and this is a cornerstone of Hamilton's work — is that inclusion in the workplace isn't treating everyone the same. It's factoring everyone's differences.

"I don't want you to treat me the same. I want you to look at my situation and treat me the way I need to be treated based on my situation," she says. "And that can be difficult to navigate, but that's what we help our clients do."

As challenging both the social unrest and pandemic has been, it's an opportunity to move forward and make a difference.

"It's a bittersweet experience when there's lots of change — there's always a lot of opportunity as well," Hamilton says. "Never waste a good crisis."

On the episode, Hamilton shares more details about her forthcoming book, advice for female founders, and more. Listen to the full interview below — or wherever you get your podcasts — and subscribe for weekly episodes.


In honor of International Women's Day on Sunday, here are three female Houston innovators to know this week. Courtesy photos

3 female Houston innovators to know this week

Who's who

In honor of International Women's Day yesterday, today's roundup of Houston innovators features three of the city's entrepreneurs.

From a French ex-pat eliminating cellulite and promoting lymphatic health to a data scientist with a growing company, here are Houston's leading ladies to keep an eye on.

Reda Hicks, founder of GotSpot Inc.

Reda Hicks created GotSpot — a digital tool that helps connect people with commercial space with people who need it. Courtesy of GotSpot

Reda Hicks is a female founder — but more importantly, she supports her fellow female founders. In a lot of ways, its another one of Hicks' side hustles.

This year for SXSW, Hicks, founder of GotSpot — a temporary space finding tool, teamed up with Denise Hamilton, founder of WatchHerWork — a professional women's resource, to create an activation at the festival on March 12 called Texas Female Founders Day, which will feature female founder-focused programming. Despite SXSW being canceled, Texas Female Founders Day will continue.

"The two of us had been to SXSW together for the past two years, and we just saw a whole where a lot of female founders were being lost," Hicks says on this week's episode of the Houston Innovators Podcast. "We can solve both of those problems by creating an experience where it's an entire day that doesn't cost attendees anything and put together a lot of different content that would be really helpful for women growing their business."

Click here to read more.

Angela Wilkins, CTO and co-CEO of Mercury Data Science

It's all a numbers game, and Angela Wilkins of Mercury Data Science is about setting up startups for success. Photo courtesy of MDS

Mercury Fund realized the power of equipping its portfolio companies with data science and artificial intelligence, and the Houston VC fund's first move was to tap data scientist Angela Wilkins to help. The efforts expanded outside Mercury's portfolio, to companies that ranged from early seed stage startups to companies that had raised over $100 million — and they wanted Wilkins' help, either with the basics of data science or execution of analytics.

"In fact, many of the more established companies were sitting on data assets with plans to build AI-enabled products but didn't have the time or people to really start that process," Wilkins says. "After helping a few companies, we realized the need was pretty deep, and bigger than the Mercury Fund portfolio."

Click here to read more.

Emeline Kuhner-Stout, founder of Élastique Athletics

Emeline Kuhner-Stout, founder of Élastique Athletics, wanted to create a product that was easy to wear and benefitted lymphatic health. Photo courtesy of Élastique Athletics

When Emeline Kuhner-Stout was new to Houston, she was a new mom and the only times she had for herself were her daily trips to the gym, and she wanted to make it worth her while.

"There were so many more things I wanted to do for myself, and I just didn't have the time," Kuhner-Stout tells InnovationMap. "It would be so much more efficient if there was a way to combine [elements] to make products that would perform for us."

She got to thinking about creating a product that promoted lymphatic health while being stylish and wearable, so she created Élastique Athletics.

Click here to read more.

This week's innovators to know are all female leaders in different industries within Houston innovation. Courtesy photos

3 female Houston innovators to know this week

Who's who

Female leaders play a huge role in the Houston innovation ecosystem. This week's innovators to know are all women — and are each representatives for different industries. From health care and nonprofits to education, meet this week's who's who of Houston innovation.

Janna Roberson, executive director of Urban Harvest

Courtesy of Urban Harvest

For the first time — thanks to Houston nonprofit Urban Harvest — Houston has caught up with the times for providing access to healthy foods in exchange for government subsidies.

"Double Up is new to Houston, this is the first time we have had a Double Up kind of program here in the metroplex, ever," says Janna Roberson, executive director of Urban Harvest. "It is something that is very common in a lot of states."

Read more about the organization here.

Beena George, chief innovation officer at the University of St. Thomas 

Courtesy of UST

Beena George is the inaugural chief innovation officer at the University of St. Thomas. The former UST business school dean takes on the role at an interesting time for higher education. In the next few years, the industry expects a sizable drop in enrollment, which means UST is tasked with positioning itself in a way that creates value for its students.

"There has been a lot of changes in the industry and in society in general that's requiring higher education institutions to react in a different way," she says. "Some of the things that we've always been doing — creating new programs, moving online, new campuses — now it's even more important to bring that to prominence and figure out how it fits with your university. Things have changed, so the rate at which you're innovating has to increase."

Read more about Beena George here.

Ayse McCracken, founder of Ignite Healthcare Network

Courtesy of Ignite

It's astounding to Ayse McCracken that, while so much of the health care industry is comprised of women, the C-suites of medical companies were mostly male. She wanted to create an organization that helps women climb those corporate ladders — and innovation and startups were a way to do it.

"As we saw this innovation economy and startup space begin to evolve in the city, it seemed that our contribution to this was that we could help incubate and find companies that had high likelihood of success," says McCracken, who is the founder of Ignite Healthcare Network — a group of female health care executives who, among other things, hosts an annual pitch competition.

Read more about Ayse McCracken here.

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Generation Park lands new facility to scale xeno-organ production

Organ innovation

Maryland-based United Therapeutics Corp. has opened a new 77,448-square-foot facility to manufacture xeno-organs in Northeast Houston’s growing biotech hub, Generation Park.

The new Houston location is United Therapeutics’ third Designated Pathogen-Free (DPF) site, named for transplant pioneers Dr. Bartley P. Griffith and Dr. Robert A. Montgomery. The company says the new facility will enable it to scale commercial production of its xeno-organs once they receive regulatory approval.

An existing DPF facility in Virginia is supporting clinical trials for the xeno-organs, and a third site in Minnesota will also focus on commercialization with the Houston site, according to the company.

Xeno-organs are organs taken from a non-human animal source and transplanted, implanted or infused into a human recipient.

Currently, United Therapeutics is advancing clinical trials to support a Biologics License Application with the U.S. Food and Drug Administration for its investigational-stage xenotransplantation, UKidney, UThymoKidney and UHeart products. The products all involve working with the genes from humans and pigs.

In 2025, Chron.com reported the company was working to construct an estimated $96 million facility to breed genetically engineered animals. Head of investor relations at United Therapeutics Dewey Steadman told the Houston Business Journal in 2025 that the pigs’ DNA will be edited. In November 2024, a 53-year-old woman in Alabama received a transplanted kidney from UKidney that had 10 gene edits. She had the transplant removed in April 2025, after her body rejected it.

The Dr. Bartley P. Griffith and Dr. Robert A. Montgomery Xenograft Production Facility requires a “strictly controlled, biosecure barrier environment, including air filtration, filtered water, filtered feed supplies, and state-of-the-art decontamination entryways,” according to the company. Being pathogen-free means it includes calibrated air and water conduits to support the transplantability of xenograft products and to prevent contamination. For energy considerations, the building also features solar arrays.

“With our third xenograft production facility now open and clinical trials underway, United Therapeutics is moving closer to its goal of providing transplantable organs to the people who need them,” Martine Rothblatt, chairperson and CEO of United Therapeutics, said in a news release. “It is fitting that this facility is named for Dr. Griffith and Dr. Montgomery, whose first-in-human surgeries turned xenotransplantation from a theoretical possibility into a clinical reality.”

The facility, which wrapped construction in August, is located at 11848 Common Dock Dr. in Generation Park, which will house manufacturing sites for pharmaceutical heavyweights Bristol Myers Squibb and Eli Lilly. Last fall, Eli Lilly tapped Generation Park for its $6.5 billion manufacturing plant, and Bristol Myers Squibb made a $2.3 billion investment in August to bring its state-of-the-art site to the master-planned commercial district.

Elon Musk's SpaceX reports profit as AI and satellite businesses booms

Booming Business

SpaceX reported a bigger quarterly profit than expected on Tuesday, October 20, as its satellite communications and artificial intelligence businesses boomed.

The company, run by Elon Musk, posted a profit for the three months through September 2026 of $4.4 billion, or 35 cents per share, reversing a year-ago loss and easily topping Wall Street's expectations. Revenue soared to $14.6 billion, up 161%.

On a conference call with analysts, Musk suggested a merger with his electric car company Tesla might be in the works, something that has been rumored for months. He said both companies formed “special committees” of independent directors to discuss the issue, though he played down the chances of an imminent deal.

“Some people out there assume that a SpaceX and Tesla merger is a certainty,” he said. “I think that would be overstating it.”

The AI business became SpaceX's largest by revenue in the third quarter, although the Starlink satellite service remains the biggest profit generator.

“They beat across all metrics and the Starlink business looks to be accelerating,” said Dan Ives, an analyst at Yorkville Ives. “This is just what (Wall) Street wanted.”

The stock rose 7.5% in after-hours trading.

Musk also told analysts that for next month's launch of its Starship rocket, SpaceX will attempt to grab both the booster and ship with mechanical arms upon return to base, a key step toward demonstrating it can reuse the massive spacecraft.

“The only way that we can extend consciousness beyond Earth on a sustained basis is with a fully reusable orbital launch vehicle,” Musk said, calling the attempt, if successful, “a massive technology milestone.”

SpaceX hopes to get Starship on a regular launch pattern in preparation for NASA's upcoming lunar missions.

The company already has huge contracts with the federal government, and House Democrats have called for investigations into those contracts and Musk’s work with the Department of Government Efficiency. Musk has spent $276 million since July in support of Republican candidates.

In a filing for its initial public offering in June, SpaceX warned that a change in control of Congress could have a “material and adverse impact on our growth and competitive position.”

Musk recently drew criticism from politicians in Washington after speeds for a military version of SpaceX's satellite communications service were slowed for Ukraine following President Donald Trump's deal to get more diesel oil from Russia amid a push to end the war. The Wall Street Journal reported Tuesday that it was Musk who ordered the slowdown, impeding Ukraine’s use of drones along the front. SpaceX did not immediately respond to an Associated Press request for comment on the Journal story.

Both Trump and Musk have denied responsibility for the slowdown.

As midterm elections near, Musk on Monday promised to give one share of SpaceX to “every kid in America” next year, though he provided no details on how the distribution would be carried out. With communities nationwide protesting the construction of large data centers and concerns about AI safety, AI companies are trying to build goodwill. Anthropic pledged to commit 5% of its shares to a new “public benefit” fund.

SpaceX shares have been under pressure over concerns that the company was spending too much on major projects to compete with rivals such as Anthropic. The company said capital expenditures totaled $19.6 billion last quarter, nearly triple the figure from a year earlier, and it forecast spending would grow to $35 billion to $40 billion in the current quarter.

Shares of SpaceX closed Tuesday at $147.79, down from a peak near $201 after its IPO, which made Musk the world’s first trillionaire at the time. But the share prices for SpaceX and Tesla have since dropped, reducing his net worth to $925 billion, according to Forbes magazine.

Tesla reports third-quarter financial results Wednesday. Last week, Tesla unveiled a new Roadster sports car that in some versions may include thrusters allowing it to briefly fly using SpaceX technology — though experts say anything usable for drivers is a long shot.

These 5 trailblazing Houston startups are leading the energy transition

meet the finalists

Houston is home to a growing number of startups reshaping what it means to be called the "Energy Capital of the World."

As part of the 2026 Houston Innovation Awards, our Energy Transition Business category honors those innovative startups that are providing solutions within renewables, climatetech, clean energy, alternative materials, circular economy and more.

Five clean energy startups have been named finalists for the 2026 award. The finalists, selected by our esteemed panel of judges, range from a lower-emission steel producer to a diagnostics platform developer working to support batteries used in data centers.

Read more about these innovative businesses, their initiatives, and their inspirational founders below. The 2026 winners will be announced on InnovationMap.com in mid-November.

Capwell Services

Methane capture company Capwell Services works to eliminate vented oil and gas emissions economically for operators. According to the company, methane emissions are vented from most oil and gas facilities due to safety protocols, and operators are not able to capture the gas cost-effectively, leading operators to emit more than 14 million metric tons of methane per year in the U.S. and Canada. Founded in 2022, Capwell specializes in low and intermittent flow vents for methane capture.

The company began as a University of Pennsylvania senior design project led by CEO Andrew Lane. It has since participated in programs with Greentown Labs, the Rice Clean Energy Accelerator and the Creative Destruction Lab Energy Cohort at Texas A&M University. The company moved to Houston in 2023 and raised a pre-seed round. It deployed two commercial units this year, according to its application.

FlowCellutions

Energytech startup FlowCellutions is developing a chemistry-agnostic diagnostics platform for flow and metal-air batteries supporting data centers and critical infrastructure. The platform is designed to help reduce operating costs, prevent failures and costly downtime, and extend battery lifetime from approximately seven years to more than 30 years. It has deployed four paid pilots and plans to take insights from the programs to develop its next-gen sensor platform technology.

CEO Becca Segel founded the company in 2022. It is a member of Greentown Labs, and Segel was a 2025 Activate Fellow. The company has raised over $2 million in non-dilutive funding and received a $1.5 million NSF SBIR Fast-Track award earlier this year.

Hertha Metals

Hertha Metals produces lower-cost, lower-emission steel and high-purity iron. The company has developed a single-step process that uses natural gas as a direct reductant instead of metallurgical coal, which cuts production costs by more than 25 percent and emissions by up to 50 percent, according to the company. The same process produces high-purity iron needed for high-purity steels and rare earth magnets. The company says it aims to "re-industrialize America’s production of critical materials."

Hertha Metals was founded by CEO Laureen Meroueh in 2022 and emerged from stealth last year with more than $17 million in venture capital funding. The company closed a $133.65 million Series A this month and also broke ground on its $100M high-purity iron factory known as Chalyx in Conroe.

Mars Materials

Clean chemical manufacturing business Mars Materials is working to convert captured carbon into resources, such as carbon fiber and wastewater treatment chemicals. The company develops and produces its drop-in chemical products in Houston and uses an in-licensed process for the National Renewable Energy Lab to produce acrylonitrile, which is used to produce plastics, synthetic fibers, and rubbers.

Founded in 2019 by CEO Aaron Fitzgerald, CTO Kristian Gubsch, and vice president of operations Trey Sheridan, the company has secured over $7.2M in financing and is backed by Bill Gates’ Breakthrough Energy, Shell, Black & Veatch, and other organizations. It won in the Minority-founded Business Category in last year's Houston Innovation Awards.

Solidec

Chemical manufacturing company Solidec has developed autonomous generators that extract molecules from water and air and convert them into pure chemicals and fuels that are free of carbon emissions on-site, eliminating the need for transport, storage, and permitting. The company was founded around innovations developed by Rice University associate professor Haotian Wang.

The company was selected for the Chevron Technology Ventures’ Catalyst Program, Greentown Labs, NSF I-Corps and was part of the first cohort of the Activate Houston program. It won first place at the 2024 startup pitch competition at CERAWeek. Solidec was founded in 2023 by Wang, who serves as an advisor, CEO Ryan DuChanois, and CTO Yang Xia. It closed a $2.5 million seed round in 2025.

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