CellChorus created a visualization AI program that helps scientists to better understand the functioning of cells, including their activation, killing and movement. Photo via Getty Images

A Houston biotech company just announced a new award of $2.5 million.

CellChorus, a spinoff of the Single Cell Lab at the University of Houston, announced the fresh funding, which comes from an SBIR (Small Business Innovation Research) grant from the National Institute of Health (NIH) through its National Center for Advancing Translational Sciences (NCATS).

CellChorus is the business behind a technology called TIMING, which stands for Time-lapse Imaging Microscopy In Nanowell Grids. It’s a visualization AI program that helps scientists to better understand the functioning of cells, including their activation, killing and movement. This more in-depth knowledge of immune cells could be instrumental in developing novel therapies in countless disorders, including cancers and infectious diseases.

“While many cell therapies have been approved and are in development, the industry needs an integrated analytical platform that provides a matrix of functional readouts, including cell phenotype and metabolism on the same cells over time,” Rebecca Berdeaux, vice president of science at CellChorus, says in a press release. “We are grateful to NCATS for its support of the development of application-specific kits that apply dynamic, functional single-cell analysis of immune cell phenotype and function. The product we will develop will increase the impact of these therapies to improve the lives of patients.”

A two-year, $2.1 million Phase II grant will begin after the company achieves predetermined milestones under a $350,000 Phase I grant that is currently taking place. As Berdeaux explained, the funds will be used to develop TIMING kits which will manufacture analytics that provide end-users with rapid, specific and predictive results to accelerate translational research and the development and manufacture of more effective cell therapies.

TIMING is more than a great idea whose time has yet to come. It has already been proven in great depth. In fact, last June, CellChorus CEO Daniel Meyer told InnovationMap that he was initially attracted to the technology because it was “very well validated.” At the time, CellChorus had just announced a $2.3 million SBIR Fast-Track grant from the National Institute of General Medical Sciences. The company also went on to win an award in the Life Science category of the 2023 Houston Innovation Awards.

That confirmation of success comes from more than 200 peer-reviewed papers that describe myriad cell types and types of therapy, all of which used data from TIMING assays. TIMING data has benefited industry leaders in everything from research and clinical development to manufacturing. With the new grant, TIMING will become more widely available to scientists making important discoveries relating to the inner workings of the cells that drive our immunity.

The projects are among 16 other early-stage research projects at U.S. colleges and universities to receive a total of $17.4 million from the DOE's Office of Fossil Energy and Carbon Management. Photo courtesy of University of Houston

3 UH projects land $17.4M in DOE funding for early-stage research

follow the money

Three projects from the University of Houston have been awarded funds from the U.S. Department of Energy for research on decarbonization and emissions.

The projects are among 16 other early-stage research projects at U.S. colleges and universities to receive a total of $17.4 million from the DOE's Office of Fossil Energy and Carbon Management (FECM).

“These three projects show the relevance and quality of the research at UH and our commitment to making a meaningful impact by addressing society’s needs and challenges by doing critical work that impacts the real world,” Ramanan Krishnamoorti, vice president for energy and innovation at UH, says in a statement. “The success of these project could attract investment, create jobs, produce clean energy, save costs, reduce carbon emissions, and benefit not only the greater Houston area, but the Gulf Coast and beyond.”

The projects were selected under FECM’s University Training and Research program, which aims to support "research and development opportunities for traditionally underrepresented communities and tap into the innovative and diverse thinking of student researchers," according to an announcement from the DOE.

Here are the projects from UH and their funding amounts:

A Comprehensive Roadmap for Repurposing Offshore Infrastructure for Clean Energy Projects in the Gulf of Mexico, $749,992 — Led by Ram Seetharam, UH Energy program officer, this project looks at ways to prolong the life of platforms, wells and pipelines in the Gulf Coast and will create a plan "covering technical, social, and regulatory aspects, as well as available resources," according to UH.

Houston Hydrogen Transportation Pilot, $750,000— Led by Christine Ehlig-Economides, Hugh Roy and Lillie Cranz Cullen, and managed by Joe Powell, this project will demonstrate the potential for a hydrogen refueling pilot in Houston. The first phase will create a system to optimize hydrogen and the second will create a workforce training network. The project is in collaboration with Prairie View A&M University.

Synergizing Minority-Serving Institution Partnerships for Carbon-Negative Geologic Hydrogen Production, $1.5 million — This project is in collaboration with Stanford Doerr School of Sustainability and Texas Tech. The project will create a visiting scholars program for students from UH and TTU, who will spend one month per year at Stanford for three years. While in the program, students will focus on creating carbon-negative hydrogen from rocks beneath the Earth's surface. Kyung Jae Lee, associate professor in the Department of Petroleum Engineering at UH, is working alongside colleagues at TTU and Stanford on this project.

Other projects in the group come from the University of Texas at El Paso, New Mexico Institute of Mining and Technology, Tennessee State University, North Carolina Agricultural and Technical State University, Duke University and more.

Last year the DOE also awarded $2 million to Harris and Montgomery counties for projects that improve energy efficiency and infrastructure in the region. Click here to read about those projects.

The DOE also granted more than $10 million in funding to four carbon capture projects with ties to Houston last summer.
Greentown Houston has received funding from the EDA. Photo via GreentownLabs.com

Houston energy tech startup incubator secures federal support to accelerate tech entrepreneurship

seeing green

Sixty organizations across the country have received a grant from the United States Department of Commerce — and one recipient is based in Houston.

Greentown Labs, dual located in Houston and Somerville, Massachusetts, has received a grant from the 10th cohort of the Economic Development Administration's “Build to Scale” program for its Houston location. The $53 million of funding was awarded to 60 organizations across 36 states, the District of Columbia, and Puerto Rico. All of the programs support technology entrepreneurs across industries.

“The Biden-Harris Administration is Investing in America to help create entrepreneurial ecosystems across the country and put quality, 21st century job opportunities in people’s backyards,” Secretary of Commerce Gina Raimondo says in the press release. “The ‘Build to Scale’ program will unlock innovation potential in regions all over the nation, improving our economic competitiveness now, and for decades to come.”

According to the EDA, Greentown, located in a growing innovation district, will receive $400,000 with a $400,000 local match confirmed. The project, named Houston Ion District Investor Activation, is described as a way to create economic opportunity through equitable capital access.

"This project capitalizes on the need for jobs and economic development, especially in communities most vulnerable to the impacts of natural disasters," reads the project abstract. "EDA funding will enable the expansion of Greentown’s Investor Program into EDIJ, in partnership with the Ion, to further climate equity and resilience in Houston and empower underrepresented entrepreneurs as the city transitions from fossil fuels to a clean energy economy."

Greentown receives of of the 2023 Capital Challenge Grant Recipients. The other competition, the Venture Challenge, also awarded funding to another Houston organization. The Urban Partnerships Community Development Corporation received $741,925 to support the BioWell Start Accelerator Program, which is committed to scaling of bio-industrial startups.

“EDA is proud to partner with this year’s ‘Build to Scale’ grantees as they fuel regional innovation hubs and technology-based economic development strategies throughout the U.S.,” Assistant Secretary of Commerce for Economic Development Alejandra Y. Castillo says in the release. “Investing in scalable startups and expanding access entrepreneurial capital will yield good-paying jobs, economic resiliency, and equitable growth in communities throughout America.”

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This article originally ran on EnergyCapital.

Houston-based Zeta Energy has fresh funding from the government. Image via Zeta Energy

Houston-based battery innovators receive $4M in federal funding

money moves

Houston-based Zeta Energy announced this week that it was selected to receive $4 million in federal funding for the development of efficient electric vehicle batteries.

The funds come from the U.S. Department of Energy's ARPA-E Electric Vehicles for American Low-Carbon Living, or EVs4ALL, program, which aims to increase the number of EVs on the roads by boosting the country’s supply chain of affordable, convenient, reliable and safe batteries.

Zeta Energy is one of 12 groups in the U.S. to receive funding from the program, which awarded $42 million in total.

“Electric vehicle sales in America have tripled since the start of this Administration and by addressing battery efficiency, resiliency and affordability, the projects announced today will make EVs attractive to even more drivers,” U.S. Secretary of Energy Jennifer M. Granholm said in a statement released earlier this week. “This is a win-win for our efforts to fight climate change and power America’s clean transportation future with technologies produced by researchers and scientists right here at home.”

Other teams to receive funding include 24M Technologies, national laboratories and universities like The Ohio State University, University of Maryland, Virginia Tech, among others. Zeta is the only Texas-based company to receive funds. It received one of the largest grants among the group.

"We are thrilled to have been selected for funding by the ARPA-E EVs4ALL program," Zeta Energy CEO Tom Pilette said in a statement. "We have been working hard to make this technology a reality, and we are really grateful to receive this recognition of the promise of our technology and the progress we have made on it."

Zeta Energy is known for its lithium sulfur batteries that traditionally have not been long lasting. While sulfur is an economical and abundant material, it traditionally would dissolve after a few uses in lithium sulfur batteries.

However, Zeta uses its proprietary sulfur-based cathodes and lithium metal anodes that have shown to have higher capacity and density and better safety profiles, according to the company's website.

According to ARPAE, the company will create a new anode that will "be highly accessible and rechargeable" with the funding.

Zeta Energy

closed a $23 million series A round led by New York VC firm Moore Strategic Ventures about a year ago. In addition to applications for electric vehicles, the company's technology is also expected to have uses in grid energy storage.
Federal relief efforts can be confusing — are are four options from a local tax expert that are reliable for small business owners. Getty Images

Tax expert shares 4 COVID-19 relief options for Houston small businesses

Guest article

There's been a lot in the news lately about large companies securing large federal grants to soften the financial blow of the CORONA shutdown — to the exclusion of smaller businesses. And even with new legislation that could provide additional funding, small companies could still be left out.

Here are four ways that companies can garner some financial relief in these challenging financial times:

1. Delay of employer FICA contributions 

While most of the attention has been focused on the forgivable loans that are part of the CARES Act, the good news is that — if you dig deeper — the legislation also provides a postponement (not forgiveness) of the employer portion of FICA payments. These are available for payroll taxes due beginning on March 27 through year's end. Payments can be deferred with half due on December 31, 2021, and the remaining half on December 31, 2022.

2. Employee retention credits

This is fully refundable tax credit available for employers equal to 50 percent of qualified wages paid to employees. The retention credit applies to qualified wages paid after March 12, 2020, though the balance of this calendar year.

There is a cap to the amount of the credit, and the credit is only available to companies that either:

  1. Fully or partially suspended operation during any calendar quarter in 2020 due to orders from an appropriate governmental authority limiting commerce, travel, or group meetings (for commercial, social, religious, or other purposes) due to COVID-19; or
  2. Experienced a significant decline in gross receipts during the calendar quarter.

3. Carrying back Net Operating Losses (NOL)

Another often missed provision of the CARES Act is the ability for companies to carry back net operating losses from 2018 or 2019 to prior years (going back 5 years) and obtain refunds of previously paid taxes. The 2017 tax reform eliminated the ability to carry back NOLs, but the CARES Act has resurrected them.

4. Families First Coronavirus Response Act (FFCRA) 

Employers with fewer than 500 employees may qualify for tax credits under the FFCRA, which was enacted on March 18. The legislation has two main sections: the Emergency Paid Sick Leave Act (EPSLA), and the Emergency Family and Medical Leave Expansion Act (FMLA Expansion).

An eligible employer may claim a fully refundable tax credit equal to 100 percent of the qualified family leave wages (and allocable qualified health plan expenses and the eligible employer's share of Medicare tax on the qualified family leave wages) it pays.

Each company's situation is different, so we strongly suggest you speak with your tax adviser to see how these provisions might apply to you.

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Jason Sharp, CPA, is tax partner at Briggs & Veselka, Houston's largest locally owned CPA firm. He can be contacted a jsharp@bvccpa.com.

Houston startup Grant Source, which helps its clients find the right grants to apply for, has seen a surge in business amid the coronavirus shutdown. Getty Images

This Houston tech startup is helping businesses find the funds during COVID-19 crisis and beyond

Taken for granted

Since 2015, Grant Source has perfected the art of helping businesses, foundations, and organizations find and secure grant funding — and now their expertise has become vital to COVID-19 response initiatives.

With the devastation caused by the novel coronavirus, America's medical organizations have been scrambling to obtain the funds required to purchase the testing kits, masks, PPE, and other life-saving products needed to help curb the effects of the global pandemic and now, thanks to the mobile and web platform, they're getting the assistance they need to accomplish that goal.

"COVID-19 response is actually our claim to fame right now," says Allen Thornton, founder and CEO of Grant Source. "We have probably done more business in the last few months than we have since we started. Simply because we are helping people find grants with the CARES Act. There's over $500 billion out there, which has created overnight a $40 billion market opportunity for us."

Grant Source has worked extensively with city, county, state, and government agencies to secure grant funding, which is why they have become a game changer for those that need emergency capital to combat COVID-19's challenges.

"Initially, it was scary because we lost some of our clients, but then a bunch of medical clients came to us and asked if we could help them find funding for COVID-19 outreach," Thornton says. "We've found that they have a higher probability of success right now because with COVID-19 outreach, the procurement cycle has gone from six to nine months down to 30 days, which is unheard of."

In addition to telemedicine companies, Grant Source has been helping write grants for clients that range from airports to technology companies in order to help provide them with a path forward in the fight against the novel coronavirus.

Grant Source has created a database and a suite of resources for companies looking for grants. Photo via grantsource.com


Preventing federal funding waste

Outside of the context of a pandemic, the government uses grants as a way to fund ideas and projects that provide public services and stimulate the economy.

Grants are also essential when it comes to supporting critical recovery initiatives and innovative research, but on a fundamental level, very few even know how or where to start when it comes to applying for one and it becomes even more esoteric when it comes to getting funded. That's why so much grant money goes unclaimed, with millions of nonprofits and businesses going underfunded and not maximizing their impact.

"Over $3.2 billion in grant money goes unclaimed every single year," says Thornton. "We have a broken system and we wondered what we could do to change it, so we started Grant Source, our revolutionary grant funding system, to help organizations find and secure money for their mission."

Client-focused services and support

In addition to helping clients find grants, Grant Source assists with the necessary pre-work to apply for a grant.

"We started out as just a database where you could find grants and grant writers," says Thornton. "But in listening to our customers, they wanted us to do everything full service, too. So, I flew all across the country from Minneapolis to Kansas to Los Angeles to Toronto and put all the top grant writing associations on retainer and created what is Grant Source today, which is pretty much mobile for grants."

Thornton says Grant Source has more than 1,500 consultants across the U.S. and Canada, and these professionals each have different specialties — much like a lawyer or a doctor — and relationships in different states.

For a flat fee that ranges from $500 to $5,000 per month, Grant Source will set out to procure its clients grants that range anywhere from $50,000 to $1 million based on their goals. To date, Grant Source has helped businesses and organizations find and secure over $6 million in grant funding.

New clients first sign up for an assessment with Grant Source that establishes what the client's goals are and how the company is set up. Once Grant Source has established a few options for the client, they get started on submitting to the grants. In order to protect its customers from the uncertainty of the process, Grant Source offers investment protection for 12 months.

"We have the investment protection so customers won't be left empty handed," says Thornton. "It's risk free, so if they don't at least get their investment back within the first 12 months, we'll either continue their grant at no cost or we'll give them a credit for the difference."

Founded from a personal need

Treating customers with fairness is important for Grant Source because they started out as a nonprofit seeking grant funding themselves and soon learned that there was a lot that they did not know about the process.

"When I was at UTSA in 2006, the African American graduation population was less than 6 percent, which was unacceptable, so we started a nonprofit," says Thornton. "We made a lot of impact in just a few years. We increased the graduation population from 6 percent to about 38 percent, And, for the 2008 election, we were able to register over 3,200 students."

After graduation, Thornton says he saw an opportunity to expand to other colleges, but lacked funding to do so.

"We saw grants as a huge opportunity and they are, but unfortunately, they're also a huge hassle and it takes a lot of time and energy and effort to even find one that you qualify for," he remembers. "And even when you do, if you don't know how to write the proposal, you're dead in the water."

After the grant process failed, Thornton's money was gone with no communication or valid reason as to why. That frustrated him to the point where he wanted to provide coherent solutions to the problem himself.

"I spent a ton of money on education and researching top grant writing associations," says Thornton. "Most people don't know where to find grants, and there are so many different types of grants and places you can find them. For instance, we're working on a federal proposal with the federal government, there's 26 different agencies that still don't even know how to talk to each other."

Creating a lasting impact

From the outset, Grant Source started creating corporate responsibility programs and impact within a cost center for organizations that were for profit companies. They seek to put them in ideal situations to create the kind of impact that warrants grant funding.

"What we teach our clients is that you can't approach the process with the idea that you will get the grant money and then go out and create come impact," says Thornton. "You have to focus on being able to showcase the impact that you're already creating and then we can go find money for that. If you can articulate the impact of whatever you're doing is creating, we can find the person that cares about that.

In addition providing the software and platform for grant seekers, Grant Source offers a book, courses, seminars, workshops, and conferences that offer the baseline information needed to secure grant funding.

"At the end of the day, Grant Source is a technology platform that helps organizations find money for their mission," says Thornton. "We've streamlined the grant writing process and the grant finding process. At Grant Source, we don't focus on the money, we focus on the impact and then we give people a clear path to make it happen."

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Houston wearable biosensing company closes $13M pre-IPO round

fresh funding

Wellysis, a Seoul, South Korea-headquartered wearable biosensing company with its U.S. subsidiary based in Houston, has closed a $13.5 million pre-IPO funding round and plans to expand its Texas operations.

The round was led by Korea Investment Partners, Kyobo Life Insurance, Kyobo Securities, Kolon Investment and a co-general partner fund backed by SBI Investment and Samsung Securities, according to a news release.

Wellysis reports that the latest round brings its total capital raised to about $30 million. The company is working toward a Korea Securities Dealers Automated Quotations listing in Q4 2026 or Q1 2027.

Wellysis is known for its continuous ECG/EKG monitor with AI reporting. Its lightweight and waterproof S-Patch cardiac monitor is designed for extended testing periods of up to 14 days on a single battery charge.

The company says that the funding will go toward commercializing the next generation of the S-Patch, known as the S-Patch MX, which will be able to capture more than 30 biometric signals, including ECG, temperature and body composition.

Wellysis also reports that it will use the funding to expand its Houston-based operations, specifically in its commercial, clinical and customer success teams.

Additionally, the company plans to accelerate the product development of two other biometric products:

  • CardioAI, an AI-powered diagnostic software platform designed to support clinical interpretation, workflow efficiency and scalable cardiac analysis
  • BioArmour, a non-medical biometric monitoring solution for the sports, public safety and defense sectors

“This pre-IPO round validates both our technology and our readiness to scale globally,” Young Juhn, CEO of Wellysis, said in the release. “With FDA-cleared solutions, expanding U.S. operations, and a strong AI roadmap, Wellysis is positioned to redefine how cardiac data is captured, interpreted, and acted upon across healthcare systems worldwide.”

Wellysis was founded in 2019 as a spinoff of Samsung. Its S-Patch runs off of a Samsung Smart Health Processor. The company's U.S. subsidiary, Wellysis USA Inc., was established in Houston in 2023 and was a resident of JLABS@TMC.

Elon Musk vows to launch solar-powered data centers in space

To Outer Space

Elon Musk vowed this week to upend another industry just as he did with cars and rockets — and once again he's taking on long odds.

The world's richest man said he wants to put as many as a million satellites into orbit to form vast, solar-powered data centers in space — a move to allow expanded use of artificial intelligence and chatbots without triggering blackouts and sending utility bills soaring.

To finance that effort, Musk combined SpaceX with his AI business on Monday, February 2, and plans a big initial public offering of the combined company.

“Space-based AI is obviously the only way to scale,” Musk wrote on SpaceX’s website, adding about his solar ambitions, “It’s always sunny in space!”

But scientists and industry experts say even Musk — who outsmarted Detroit to turn Tesla into the world’s most valuable automaker — faces formidable technical, financial and environmental obstacles.

Feeling the heat

Capturing the sun’s energy from space to run chatbots and other AI tools would ease pressure on power grids and cut demand for sprawling computing warehouses that are consuming farms and forests and vast amounts of water to cool.

But space presents its own set of problems.

Data centers generate enormous heat. Space seems to offer a solution because it is cold. But it is also a vacuum, trapping heat inside objects in the same way that a Thermos keeps coffee hot using double walls with no air between them.

“An uncooled computer chip in space would overheat and melt much faster than one on Earth,” said Josep Jornet, a computer and electrical engineering professor at Northeastern University.

One fix is to build giant radiator panels that glow in infrared light to push the heat “out into the dark void,” says Jornet, noting that the technology has worked on a small scale, including on the International Space Station. But for Musk's data centers, he says, it would require an array of “massive, fragile structures that have never been built before.”

Floating debris

Then there is space junk.

A single malfunctioning satellite breaking down or losing orbit could trigger a cascade of collisions, potentially disrupting emergency communications, weather forecasting and other services.

Musk noted in a recent regulatory filing that he has had only one “low-velocity debris generating event" in seven years running Starlink, his satellite communications network. Starlink has operated about 10,000 satellites — but that's a fraction of the million or so he now plans to put in space.

“We could reach a tipping point where the chance of collision is going to be too great," said University at Buffalo's John Crassidis, a former NASA engineer. “And these objects are going fast -- 17,500 miles per hour. There could be very violent collisions."

No repair crews

Even without collisions, satellites fail, chips degrade, parts break.

Special GPU graphics chips used by AI companies, for instance, can become damaged and need to be replaced.

“On Earth, what you would do is send someone down to the data center," said Baiju Bhatt, CEO of Aetherflux, a space-based solar energy company. "You replace the server, you replace the GPU, you’d do some surgery on that thing and you’d slide it back in.”

But no such repair crew exists in orbit, and those GPUs in space could get damaged due to their exposure to high-energy particles from the sun.

Bhatt says one workaround is to overprovision the satellite with extra chips to replace the ones that fail. But that’s an expensive proposition given they are likely to cost tens of thousands of dollars each, and current Starlink satellites only have a lifespan of about five years.

Competition — and leverage

Musk is not alone trying to solve these problems.

A company in Redmond, Washington, called Starcloud, launched a satellite in November carrying a single Nvidia-made AI computer chip to test out how it would fare in space. Google is exploring orbital data centers in a venture it calls Project Suncatcher. And Jeff Bezos’ Blue Origin announced plans in January for a constellation of more than 5,000 satellites to start launching late next year, though its focus has been more on communications than AI.

Still, Musk has an edge: He's got rockets.

Starcloud had to use one of his Falcon rockets to put its chip in space last year. Aetherflux plans to send a set of chips it calls a Galactic Brain to space on a SpaceX rocket later this year. And Google may also need to turn to Musk to get its first two planned prototype satellites off the ground by early next year.

Pierre Lionnet, a research director at the trade association Eurospace, says Musk routinely charges rivals far more than he charges himself —- as much as $20,000 per kilo of payload versus $2,000 internally.

He said Musk’s announcements this week signal that he plans to use that advantage to win this new space race.

“When he says we are going to put these data centers in space, it’s a way of telling the others we will keep these low launch costs for myself,” said Lionnet. “It’s a kind of powerplay.”

Johnson Space Center and UT partner to expand research, workforce development

onward and upward

NASA’s Johnson Space Center in Houston has forged a partnership with the University of Texas System to expand collaboration on research, workforce development and education that supports space exploration and national security.

“It’s an exciting time for the UT System and NASA to come together in new ways because Texas is at the epicenter of America’s space future. It’s an area where America is dominant, and we are committed as a university system to maintaining and growing that dominance,” Dr. John Zerwas, chancellor of the UT System, said in a news release.

Vanessa Wyche, director of Johnson Space Center, added that the partnership with the UT System “will enable us to meet our nation’s exploration goals and advance the future of space exploration.”

The news release noted that UT Health Houston and the UT Medical Branch in Galveston already collaborate with NASA. The UT Medical Branch’s aerospace medicine residency program and UT Health Houston’s space medicine program train NASA astronauts.

“We’re living through a unique moment where aerospace innovation, national security, economic transformation, and scientific discovery are converging like never before in Texas," Zerwas said. “UT institutions are uniquely positioned to partner with NASA in building a stronger and safer Texas.”

Zerwas became chancellor of the UT System in 2025. He joined the system in 2019 as executive vice chancellor for health affairs. Zerwas represented northwestern Ford Bend County in the Texas House from 2007 to 2019.

In 1996, he co-founded a Houston-area medical practice that became part of US Anesthesia Partners in 2012. He remained active in the practice until joining the UT System. Zerwas was chief medical officer of the Memorial Hermann Hospital System from 2003 to 2008 and was its chief physician integration officer until 2009.

Zerwas, a 1973 graduate of the Houston area’s Bellaire High School, is an alumnus of the University of Houston and Baylor College of Medicine.