Know before you go: 2024 H-Town Roundup

Plan your week

Here's what you need to know about HTR this year. Photo courtesy

Next week, Houston Exponential's annual week of innovation and networking is taking place. Here are five things you need to know before you go.

1. New year, new name.

Houston Tech Rodeo, which originated in 2020, has been rebranded to H-Town Roundup, but the week of innovation and entrepreneurship still has the same goal of providing programming and events that connect and educate Houstonians.

On a recent episode of the Houston Innovators Podcast, Natara Branch, CEO of Houston Exponential, says the change is meant to make for a more inclusive experience for entrepreneurs of small businesses, something she's seen a need for since she took on her role last year.

"This year, we've had the better part of a year to think about what can be different and how can we serve the founder," she says.

Branch explains that some members of the Houston community confused the event for being associated with the Houston Livestock Show and Rodeo or for being only for true tech people. Branch says the wanted to open the door a little wider to entrepreneurs who are innovative without necessarily working in technology.

"That's not what we wanted — to exclude anyone," she says. "H-Town Roundup is going to allow us to be more inclusive."

2. It's completely free to attend.

Dozens of events are taking place around town, and all are free to Houston entrepreneurs, investors, and more. Simply register for anything you're able to attend.

For reference, a full, detailed agenda is available online too.

3. There are two featured events.

Need to make some priorities? This year, there are two featured events for HTR.

  • Tech and Tequila Talk powered by Blue People at 5 to 7:30 pm, on Tuesday, February 27, at the UH Tech Bridge Innovation Center.
  • CodeLaunch Houston at 4 to 9 pm, on Wednesday, February 28, at Bayou Music Center.

4. Introducing: The Founder Lounge.

For attendees with the founder pass, The Founder's Lounge at Esperson Building in downtown is open Monday through Thursday from 10 am to 3 pm next week.

The full agenda of talks planned at the lounge is online.

5. Find the activity zones.

HTR again is rotating venues. Here's where and when you can expect to find HTR activities.

  • Sunday (1 to 5 pm) - Esperson Building
  • Monday (8 am to 12:30 pm) - TMC Innovation
  • Monday (1:30 to 5 pm) - The Cannon Downtown
  • Tuesday (1 to 7:30 pm) - UH Tech Bridge
  • Wednesday (10 am to 1 pm) - Esperson Building
  • Wednesday (4 to 9 pm) - Bayou Music Center
  • Thursday ( 8 am to noon) - HCC Central Campus
  • Thursday (1 to 7 pm) - Greentown Labs
  • Friday (9 am to 3:30 pm) - the Ion
  • Saturday (10 am to 2 pm) - Esperson Building

Spaces, an Amsterdam-based coworking space company that entered the Houston market with a lease in Kirby Grove announced in 2017, has two more Spaces locations planned for end of 2019. Courtesy of Midway

International workspace company announces 2 more Houston coworking spots

Space(s) city

An Amsterdam-based coworking company is doubling down on Houston with the announcement of over 120,000 square feet to deliver before the end of the year.

Spaces, which first entered the Houston market with the 2017 announcement of its Kirby Grove lease, will be opening new locations in CITYCENTRE and GreenStreet, according to a news release. All three properties are owned and operated by Midway Properties.

"Spaces is redefining the way work is done, providing a contemporary, social and creative environment with a real focus on community," says Michael Berretta, vice president of Network Development, for IWG, which owns Spaces, in the release. "Houston is a vibrant city with a global business hub and an entrepreneurial attitude. Spaces gives Houston's talent pool an inspiring place to work and meet with other people who believe in the power of collaboration to drive a business forward."

Spaces has over 3,300 flexible workspace locations across the world. There are three locations open in Texas — the other two being in the Dallas area. In addition to the two expected Midway properties, a third location in Two Post Oak Central is expected to deliver in 2019, the Houston Business Journal reports.

The GreenStreet location in downtown Houston will have 63,000 square feet of workspace in repurposed retail space. Among the features promised are open space, smaller team rooms, private offices, phone booths, and a 3,000-square foot rooftop patio.

The news of the workspace follows closely behind an international accelerator program, MassChallenge, announced its Houston program in GreenStreet.

The CITYCENTRE workspace will take up almost 61,000 square feet of CITYCENTRE One and touts similar features and flexible space. Both locations also boast of existing shopping, dining, and entertainment perks in the centers.

"Spaces fits perfectly in GreenStreet, a mixed-use district that is being redeveloped as the new model of urban lifestyle,"sys Chris Seckinger, vice president and investment manager for Midway, in the release. "And CITYCENTRE gives Spaces an ideal platform to serve businesses, whether they are collaborating globally or locally, in the midst of West Houston's concentration of energy, technology and engineering firms."

Earlier this month, a report found that over the past two and a half years, Houston's coworking space has only grown marginally. With the announcement of Spaces' expansion — as well as The Cannon and The Ion projects — expected to deliver over the next two years, Houston stands to make up for lost times, so to speak.

Station Houston's stakeholders voted in favor of the organization transitioning to a nonprofit. Station Houston/Facebook

Station Houston announces its transition into becoming a nonprofit

Cha-cha-changes

Houston's startup scene just got a little more accessible. Station Houston's stakeholders voted to transition the organization to nonprofit status from the C-corp status it currently holds.

The status change is effective January 1, 2019, for the acceleration hub, which is based in downtown Houston. The news was announced to its members in an email sent on December 13.

"Following in the footsteps of successful hubs such as 1871 in Chicago or Mass Challenge in Boston, we see that non-profit status allows these organizations to stay true to their missions while providing best-in-class services to members," reads the email. "We are excited to announce that this week, all Station stakeholders voted in favor of the conversion to non-profit status."

Station's CEO, Gabriella Rowe, tells InnovationMap that the announcement is part of a larger change for the organization, which will announce its plans for Station 3.0 in January.

"This opens up so many more funding and programing opportunities for us, so that we can charge our entrepreneurs and startups as little as possible and give them all the depth of services and support," Rowe says. "That's really what it comes down to."

Station Houston is among the partners — along with the Rice Alliance for Technology and Entrepreneurship — for the Houston innovation district that plans to open in the rehabilitated Sears building in Midtown. The space plans to open in 2020 and hasn't yet broken ground. Rowe discussed Station 3.0 and the district in an interview with InnovationMap in November.

"We're going to be doing a huge launch of Station 3.0 in January," she said in the interview. "It will really allow us to tell the world not just what we're going to be for the next three months, but what we're going to be over the next three years."

Station Houston recently hosted the Texas Digital Summit with Rice University and the Rice Alliance. The all-day summit consisted of panel discussions, keynote speakers, and a startup pitch of 39 companies. At the conclusion of the day, Rowe and Brad Burke from Rice announced 10 of the most promising startups from the summit. You can read about those companies here.

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”