Here's who to know in innovation this week in Houston. Courtesy photos

As we head into May, this week's Houston innovators are all thought leaders keeping our city and state at the forefront of technology and innovation — from consulting to real estate, and everything in between.

Amy Chronis, managing partner of the Houston office of Deloitte

Amy Chronis runs the Houston office of Deloitte and serves on the sustainability board for the GHP. AlexandersPortraits.com

Shortly after Amy Chronis was named as Deloitte's Houston managing partner, she got the call to join the sustainability committee for the Greater Houston Partnership. Chronis did not take this position lightly, she says, and she immediately started researching what Houston needed as a business ecosystem.

In March, as the chair for the organization's sustainability committee, she brought together a group of constituents to engage in a Smart Cities study with the goal to identify what Houston needs to focus on — what it wanted to be known for. She learned a lot about the city through the study.

"It's affirming how much all types of people with different backgrounds care and are interested in this topic and are highly desirous of our region moving forward," she says. "I also learned that things are more complicated or difficult than we would like — in terms of funding initiatives, for instance." Read the full story here.

Brad Deutser, author and founder of the Deutser Clarity Institute

DCI has been described as the "Wonkaland for business." Courtesy of DCI

Brad Deutser is taking his approach to business consulting and creative thinking to a whole new level with the Deutser Clarity Institute. The idea accelerator, think tank, and learning lab opens this week in Uptown.

"The Deutser Clarity Institute has captured the imagination of leaders across the country," says Deutser in a release. "Even with the available science on environmental design and leadership learning, we took a chance and pushed creativity and innovation to the farthest reaches to develop a fundamentally different space, way of learning and learning curriculum. We are also producing game changing research which will influence how leaders drive engagement." (Deutser serves on the board of InnovationMap.) Read the full story here.

Alex Doublet, CEO of Door.com

Buying a home is more digitized than ever — and here's how that's affecting the industry. Photo courtesy of Door

Alex Doublet is an honorary Houston innovator to know this week after he authored a guest article about technology trends in real estate that greatly affect Houston real estate. The Dallasite cites a recent lawsuit in which homesellers claim The National Association of Realtors, Realogy Holdings Corp., HomeServices of America, RE/MAX Holdings, Inc., and Keller Williams Realty, Inc. violated the federal antitrust law by conspiring the sellers to pay an inflated amount to the buyer's broker.

"The lawsuit highlights a new need for home buyers and sellers: transparency," writes Doublet. "Gone are the days when real estate agents can take a hefty commission from his or her clients without providing value that is worthy of the price tag. The sellers who came forward to shed light on this issue have provided further proof that the current real estate model is outdated, and some serious changes could be on the way." Read Doublet's article here.

Buying a home is more digitized than ever — and here's how that's affecting the industry. Photo courtesy of HAR

How technology is disrupting — and improving — the real estate industry in Texas

Modern moving

A recent lawsuit is rocking the residential real estate industry across the country. Home sellers whose properties were listed on one of 20 MLSs claim The National Association of Realtors, Realogy Holdings Corp., HomeServices of America, RE/MAX Holdings, Inc., and Keller Williams Realty, Inc. violated the federal antitrust law by conspiring the sellers to pay an inflated amount to the buyer's broker.

The lawsuit highlights a new need for home buyers and sellers: transparency. Gone are the days when real estate agents can take a hefty commission from his or her clients without providing value that is worthy of the price tag. The sellers who came forward to shed light on this issue have provided further proof that the current real estate model is outdated, and some serious changes could be on the way.

Our next moves as a united industry in the wake of this lawsuit are critical. It is critical that we react positively. It is critical that we bring more value and transparency to our customers, and it is critical that we utilize the technology we now have at our hands to do so.

How is technology finding its way into real estate? Here are a few ways in the evolving world of home buying and selling has evolved over the past five years:

Online searching 

Everything can be done online. In most modern real estate transactions, the buyer has already found the house they want before they even contact an agent to begin the process. To put that into numbers, 95 percent of buyers are looking for their home online, and over half find it before they engage an agent, according to the National Association of Realtors. Despite the fact that this big chunk of the traditional real estate agent's job has been cut out, the commission is still the same and the buyer will have to pay it indirectly through a higher listing price on the home.

Evolving past commissions and working towards a focus on the customer experience is the only way to provide value and stay relevant in the world of apps and search bars.

Accurate valuations 

Algorithms and accuracy in information gathering are imperative to a successful real estate transaction. Traditional agents will often come to a potential seller client with high dollar signs, telling them they should list their home for a high price. This is a tactic used to earn the seller's business. Where is the data behind that hefty price? What kind of algorithm did the agent use to value the home?

Modern real estate brokerages should be utilizing advanced valuation algorithms to bring an accurate value of the home to the seller instead of wooing them with an unattainable price.

Targeted marketing

Due to the high dependency of the internet, mass marketing in physical publications aren't as effective as they once were — consumers have more options to find what they need faster. Fifty percent of people that will ever see a home that is advertised online will see it in the first seven days on the market. We all know the importance of target marketing, and here's where social media comes in.

Targeting the right people on Facebook, Instagram, Pinterest, and Google will get a home sold faster than a newspaper or magazine can even be published. Effective agents will have built online audiences for each type of home to ensure a faster sale.

Simplifying and increasing visibility

Remember how important transparency is? Simplifying and streamlining the process is right up there with it on the priority list. Luckily, there's an easy way to solve both: custom portals. Clients love the fact that they can login and see their entire buying or selling experience in one neatly packaged, convenient tool.

The modern tools now at the hands of real estate brokerages should not diminish service, but rather enhance it. Acting as a specialized guide and using the technology to bring incredible value to clients should be the new norm when it comes to real estate transactions.

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Alex Doubet is the founder and CEO of Door, Inc. (Door.com), which is a residential real estate startup company based in Texas.

Texas startups should be getting funded with Texas money, and here's why. Getty Images

Why it's important for Texas startups to get funding within the Lone Star State

Stay local

When you set out to disrupt a long-standing industry, one of the most important aspects is figuring out where you are going to get the money. Odds are, you are going to be OK with breaking the mold on other traditional practices such as forgoing the venture capitalist firms for smaller companies who share your innovative vision and want to invest in it.

That philosophy works well in Texas seeing as the big venture capitalists tend to stay on the East and West Coasts.

There are dozens of things to think about when starting a company. Funding can be the most important, and there are many ways to approach raising funding for your startup. Here are a few things to consider.

Think local

They say everything is bigger in Texas, and one thing is for certain, the Texas economy is thriving and historically very stable. Five of the top 10 fastest-growing cities in the U.S. are in Texas, and a recent Federal Reserve Bank of Dallas report found that Texas is the top state for corporate relocations due to our business-friendly climate.

Benefits of the Texas economy

Business owners and investors alike are noticing the rapid job growth, low tax rates, minimal regulation, successful economic development, and the fact that Texas is the largest exporting state in the nation.

It's important to explore and evaluate all of your options because there are investors everywhere – big and small. I explored fundraising in other states and had I gone that route, it most likely would have led to a successful fundraising campaign. However, it would have looked a lot different. I learned during the first round of fundraising that as much as the angel investment matters, the first meaningful investment might matter even more.

Explore family office investors — it's personal

Traditionally, companies looking for investors seek out the venture capitalist firms with deep pockets. You can joke that Texas is a venture capitalist desert. Compared to the "coasts," there are not many venture capitalist firms here.

I realized that what Texas does have plenty of, is family office investors. And I quickly learned that it was this type of organization that I truly desired. Why? Because local family offices are more likely to share your "homegrown" startup vision. They have true vested interest and it is really personal for them.

Also, the younger generations of these family businesses often lead the way in extending beyond oil wells, fracking, shopping centers and agriculture in seeking to invest in technology startups.

Expert tip: We used our personal connections to target regional investors such as Court Wescott; the founder of 1-800-Flowers; retired Hollywood Casinos CEO Jack Pratt; The Murchison Family; and residential real estate developer Phillip Huffines. We were able to successfully reach around $12 million in the Series A round of fundraising.

When we were ready for the next round of fundraising, we had everything we needed right here in Texas.

Great ideas get funded

Venture capitalists who put a lot of money into a lot of companies also delegate to those companies a lifespan, or a timeline for getting their money back.

Since the family offices believed in our concept and understood what we were doing, we were seen as more of a long-term investment and therefore given a longer time horizon than we would if we had gone the more traditional route of fundraising.

Investors like to watch their investments grow and typically they have more money for second and third rounds of funding when you can prove your success in the first few years.

The bottom line: Investing in Texas companies is a beneficial strategy due to the Lone Star State's booming economy and investing in companies that you believe in makes for a more meaningful relationship, which helps everyone involved succeed.

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Alex Doubet is the CEO and founder of Door Inc., a Texas-based, tech-infused real estate platform.

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Axiom Space-tested cancer drug advances to clinical trials

mission critical

A cancer-fighting drug tested aboard several Axiom Space missions is moving forward to clinical trials.

Rebecsinib, which targets a cancer cloning and immune evasion gene, ADAR1, has received FDA approval to enter clinical trials under active Investigational New Drug (IND) status, according to a news release. The drug was tested aboard Axiom Mission 2 (Ax-2) and Axiom Mission 3 (Ax-3). It was developed by Aspera Biomedicine, led by Dr. Catriona Jamieson, director of the UC San Diego Sanford Stem Cell Institute (SSCI).

The San Diego-based Aspera team and Houston-based Axiom partnered to allow Rebecsinib to be tested in microgravity. Tumors have been shown to grow more rapidly in microgravity and even mimic how aggressive cancers can develop in patients.

“In terms of tumor growth, we see a doubling in growth of these little mini-tumors in just 10 days,” Jamieson explained in the release.

Rebecsinib took part in the patient-derived tumor organoid testing aboard the International Space Station. Similar testing is planned to continue on Axiom Station, the company's commercial space station that's currently under development.

Additionally, the drug will be tested aboard Ax-4 under its active IND status, which was targeted to launch June 25.

“We anticipate that this monumental mission will inform the expanded development of the first ADAR1 inhibitory cancer stem cell targeting drug for a broad array of cancers," Jamieson added.

According to Axiom, the milestone represents the potential for commercial space collaborations.

“We’re proud to work with Aspera Biomedicines and the UC San Diego Sanford Stem Cell Institute, as together we have achieved a historic milestone, and we’re even more excited for what’s to come,” Tejpaul Bhatia, the new CEO of Axiom Space, said in the release. “This is how we crack the code of the space economy – uniting public and private partners to turn microgravity into a launchpad for breakthroughs.”

Chevron enters the lithium market with major Texas land acquisition

to market

Chevron U.S.A., a subsidiary of Houston-based energy company Chevron, has taken its first big step toward establishing a commercial-scale lithium business.

Chevron acquired leaseholds totaling about 125,000 acres in Northeast Texas and southwest Arkansas from TerraVolta Resources and East Texas Natural Resources. The acreage contains a high amount of lithium, which Chevron plans to extract from brines produced from the subsurface.

Lithium-ion batteries are used in an array of technologies, such as smartwatches, e-bikes, pacemakers, and batteries for electric vehicles, according to Chevron. The International Energy Agency estimates lithium demand could grow more than 400 percent by 2040.

“This acquisition represents a strategic investment to support energy manufacturing and expand U.S.-based critical mineral supplies,” Jeff Gustavson, president of Chevron New Energies, said in a news release. “Establishing domestic and resilient lithium supply chains is essential not only to maintaining U.S. energy leadership but also to meeting the growing demand from customers.”

Rania Yacoub, corporate business development manager at Chevron New Energies, said that amid heightening demand, lithium is “one of the world’s most sought-after natural resources.”

“Chevron is looking to help meet that demand and drive U.S. energy competitiveness by sourcing lithium domestically,” Yacoub said.

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This article originally appeared on EnergyCapital.