Houston is now home to Kodiak and Ryder's autonomous "truckport" facility. Photo courtesy of Kodiak

In a major step toward driverless freight trucks hitting Houston-area roads, a facility for loading and unloading autonomous trucks opened recently near George Bush Intercontinental/Houston Airport

Miami-based transportation and logistics company Ryder operates the “truckport” for Mountain View, California-based Kodiak Robotics, which runs a network of autonomous freight trucks. The facility, located at 888 E. Airtex Dr., opened in December. It’s next to a Ryder maintenance center.

“The truckport can currently receive several truckloads per day, and the size of the Ryder facility provides the opportunity to scale much larger than that,” says Daniel Goff, director of external affairs at Kodiak.

“The number of employees stationed at the facility fluctuates day by day,” Goff adds. “Kodiak’s team that staffs the facility in this initial phase operates on a flexible schedule to align with the needs of the trucks that are utilizing the truckport.”

The Houston site is the first Kodiak truckport to be located at a Ryder facility. It serves freight routes to and from Houston, Dallas, and Oklahoma City.

Kodiak currently operates all routes with drivers on board, including its Houston-Dallas and Houston-Oklahoma City routes. The company plans to roll out its first driverless operations on Dallas-Houston route later this year, with the new Houston facility serving as a launchpad.

“Ryder’s industry-leading fleet services and vast footprint of service locations makes it an ideal partner as we scale autonomous trucks,” Don Burnette, founder and CEO of Kodiak, says in a news release. “Expanding our network of truckports with Ryder will enable us to operate autonomous trucks at scale with our customers.”

The most recent version of Kodiak’s truck debuted in Las Vegas at the recent 2024 Consumer Electronics Show (CES). Kodiak says the truck is equipped with safety-oriented software and hardware (including braking, steering and sensors).

Kodiak’s sixth-generation truck builds on the company’s track record of real-world testing, which includes carrying 5,000 loads over more than 2.5 million miles.

Founded in 2018, Kodiak has been delivering freight in Texas since mid-2019, including on the Houston-Dallas route. Kodiak announced in 2022 that it had teamed up with Swedish retailer IKEA to pilot autonomous freight deliveries in Texas between the IKEA warehouse in Baytown and the IKEA store in Frisco.

Kodiak Robotics unveiled its driverless semi-truck technology this month, which is expected to hit Texas roads later this year. Photo via Kodiak

Driverless semi-truck tech to launch between Houston and Dallas later this year

coming soon

Kodiak Robotics is scaling up its driverless semi truck, which will initially carry cargo on a Houston-to-Dallas route that’s set to formally launch this year.

The most recent version of Kodiak’s truck debuted in Las Vegas at the recent 2024 Consumer Electronics Show (CES). Mountain View, California-based Kodiak Robotics says the truck is equipped with safety-critical software and hardware (including braking, steering and sensors).

Kodiak’s sixth-generation truck builds on the company’s five years of real-world testing, which includes carrying 5,000 loads over more than 2.5 million miles.

“We’re the first and only company to have developed a feature-complete driverless semitruck with the level of automotive-grade safety redundancy necessary to deploy on public roads,” Don Burnette, founder and CEO of Kodiak, says in a news release.

“Over the course of 2.5 million miles, we’ve successfully demonstrated that our self-driving trucks can withstand the harsh environment of long-haul trucking from both a platform integrity and a software perspective,” he adds. “This truck fundamentally demonstrates that we’ve done the work necessary to safely handle driverless operations.”

Among the highlights of the sixth-generation truck are:

  • A pneumatic braking system controlled by Kodiak’s proprietary software.
  • A redundant steering system.
  • A proprietary safety computer.
  • A redundant power system.
  • Proprietary SensorPods for housing sensors.
  • Microphones designed to detect the presence of the sirens of emergency vehicles and other suspicious sounds.
  • An advanced communication system.

Founded in 2018, Kodiak has been delivering freight in Texas since mid-2019, including a Houston-to-Dallas route. Kodiak announced in 2022 that it had teamed up with Swedish retailer IKEA to pilot autonomous freight deliveries in Texas between the IKEA warehouse in Baytown and the IKEA store in Frisco.

The company wants to make Texas "the home of self-driving trucks." PRNewsfoto/Kodiak Robotics

Self-driving semi trucks are now hauling cargo in and out of Houston

Autopilot

The Interstate 45 freight corridor between Houston and Dallas now serves as a testing ground for self-driving cargo trucks.

Silicon Valley startup Kodiak Robotics Inc. recently began sending its autonomous 18-wheel trucks on trips between Texas' two largest metro areas, co-founder and CEO Don Burnette says. The trucks are carrying paid cargo, but Kodiak won't identify the customer or customers. The company also won't say how many trips the trucks are making each day.

The Texas initiative represents Kodiak's first foray into commercial deliveries. Wired.com notes that pretty much every player in the autonomous truck sector has conducted tests in Texas or is carrying commercial loads in the Lone Star State, which boasts more than 2,300 miles of interstate highways.

For its part, Kodiak aims to make Texas "the home of self-driving trucks."

According to a 2016 report from the Texas Department of Transportation, nearly half of all truck freight in Texas goes through the I-45 corridor's 11 counties. In some spots, trucks make up more than one-fourth of the traffic in the corridor, which runs 276 miles from Galveston to where I-45 intersects with Interstate 20 in Dallas County, the TxDOT report says.

"The importance of the I‐45 freight corridor to the movement of goods extends beyond Texas because much of the freight originating or passing through the corridor is destined to other domestic and international markets," the report says.

For now, Burnette says, two people are aboard each Kodiak truck traveling between Houston and Dallas — a safety driver and a safety engineer.

"Dallas will be our home base for testing and operations for the foreseeable future," Burnette says. "Kodiak plans to continue refining and testing its trucks until the last truck-involved accident happens on public roads."

Kodiak's Dallas office, which opened in March, employs eight people. The company plans to relocate soon to new office space in the Dallas suburb of Lancaster, Burnette says.

At this time, Kodiak doesn't plan to hire any workers in Houston, he says.

From its base in the Dallas area, Kodiak envisions expanding its service to routes throughout Texas, but it's focusing solely on the Houston-to-Dallas route for the time being, Burnette says.

Kodiak picked Texas for its truck tests, in part, because of the "warm welcome" extended by Gov. Greg Abbott, TxDOT, the Texas Department of Public Safety, the Texas A&M Transportation Institute, and other segments of the public sector, he says.

In addition, Burnette says, Kodiak chose Texas "because of its great people, freight-rich economy, reasonable regulatory structure, and robust infrastructure."

In 2017, Texas enacted laws enabling driverless vehicles, including long-haul trucks, to operate on the state's roads.

"Texas is a leader in the testing and implementation of connected and automated vehicles, and Kodiak's willingness to partner with academia and public agencies to ensure safe deployment of new technology will add significant value to our transportation system," Christopher Poe, assistant director of the Texas A&M Transportation Institute, says in a release.

Burnette, co-founder of Otto Trucking LLC, a self-driving truck startup purchased in 2016 by Uber Technologies Inc., and fellow entrepreneur Paz Eshel established Kodiak in 2018 to "redefine" long-haul trucking through self-driving technology.

Kodiak says its autonomous technology is designed to ease pressures facing the trucking industry, including a shortage of drivers and high turnover among drivers, while improving highway safety, fostering business efficiency, reducing traffic congestion, and cutting down on harmful emissions.

"Long-haul trucking is primed for autonomous technology," Kodiak says in a post on Medium. "Highway driving is more structured and predictable than urban driving. This means there are fewer decisions for drivers to make and [it's] a better fit for autonomous vehicles."

"As hard as it is to navigate city streets, autonomous vehicles are much closer to being able to drive on more structured interstate highways, which have no jaywalking pedestrians, no aggressive cyclists, and no runaway pets," Kodiak adds. "That's why we've focused on building technology specifically for long-haul trucks driving on highway routes, often referred to as the 'middle mile.'"

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.