4 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Aleece Hobson of HX Venture Fund, Denis Akhiyarov of AiKYNETIX, and Sean Harkins and Brien Beach of AMPD Labs. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from additive manufacturing to venture capital — recently making headlines in Houston innovation.

Aleece Hobson, venture partner for the HX Venture Fund

Aleece Hobson of HX Venture Fund shares what people can expect from Venture Houston on this week's episode of the Houston Innovators Podcast. Photo courtesy of HXVF

Today is a big day for Aleece Hobson — venture partner for the HX Venture Fund, a fund of funds investing in venture capital firms across the country that have interest in investing in Houston companies. She joined the Houston Innovators Podcast last week to discuss Venture Houston, which takes place today, and why it is so important to HXVF to showcase Houston.

"Houston is a destination for innovation — we are not a flyover city," she says on the show. Click here to read more and stream the podcast.

Denis Akhiyarov, CEO and co-founder of AiKYNETIX

Houston-based AiKYNETIX is equipping runners with high-tech tracking tools. Image courtesy of AiKYNETIX

Houstonain Denis Akhiyarov wanted to design a way to easily improve running performance. He founded AiKYNETIX uses real-time technology to provide a new option for runners on treadmills.

“Runners spend a lot of time, energy and money to run better,” says Akhiyarov, CEO and co-founder of the company. “In my personal life with training for nine marathons, I’ve seen limitations with wearables, they don’t actually track running form while running. Overall, our technology tracks not only your basic parameters but it can also analyze the human running form while in motion.”

AiKYNETIX, which was founded in January 2021, is positioned to replace power meters and can make a treadmill smarter. It has ability to plug into interactive video platforms for sports and serves as a much cheaper and more widely available analysis tool outside of motion capture labs, he says. Click here to read more.

Sean Harkins and Brien Beach, co-founders of AMPD Labs

Sean Harkins and Brien Beach opened AmPd Labs' space in the Heights last month. Images via ampdlabs.llc

Last year, Sean Harkins introduced his friend Brien Beach to the world of additive manufacturing, and together the duo saw a business opportunity not only for themselves — but also for all of Houston.

Harkins had been working in 3D printing and additive manufacturing — the process of creating an object by building it one layer at a time — for the last decade and studied industrial design at the University of Houston. Working together, Harkins and Beach launched AmPd Labs, Houston’s next-generation additive manufacturing facility for industrial design and production.

“There is a hill to climb with market acceptance, but we want to be the champions of that and Houston is just a great place to start this because it's the largest industrial city in America and there's so much industry here and there's tons of engineers in this community,” says Beach. “Houston is such a business-forward place. A ‘how can I help you’ type of business place.” Click here to read more.

Houston-based AiKYNETIX is equipping runners with high-tech tracking tools. Image courtesy of AiKYNETIX

Houston sports tech startup is enhancing performance metrics for runners and athletes

sweat tech

With the Houston Marathon only five months away, a new application using human motion insights could help a runner refine their form to reach peak performance – all from the convenience of their smart phone.

While traditional treadmills are limited in training feedback and wearables are not designed to track elevation, Houston-based AiKYNETIX uses real-time technology to provide a new option for runners on treadmills.

“Runners spend a lot of time, energy and money to run better,” says Denis Akhiyarov, CEO and co-founder. “In my personal life with training for nine marathons, I’ve seen limitations with wearables, they don’t actually track running form while running. Overall, our technology tracks not only your basic parameters but it can also analyze the human running form while in motion.”

AiKYNETIX, which was founded in January 2021, is positioned to replace power meters and can make a treadmill smarter. It has ability to plug into interactive video platforms for sports and serves as a much cheaper and more widely available analysis tool outside of motion capture labs, he says.

“Motion analysis is becoming important in sports,” says Akhiyarov, a data scientist who previously worked as a developer in machine learning. “We want to make this expensive fitness technology available for everyone.”

The current target market for the technology is tech-savvy triathletes, however, there are wider applications for the technology including for coaches to get real-time performance metrics. Also, there are medical applications such as for rehabilitation and injury prevention.

“One of the discoveries for us is seeing differences between runners using different shoes,” says cofounder and Rice University MBA Anton Galvas. “It’s very interesting to see how much energy you preserve depending on what kind of shoe you wear.”

The team’s primary market for sale is the IOS app store but they plan to expand to fitness platforms for integration and have seen interest from treadmill companies for potential partnerships.

There are other current competitor solutions that require special hardware and wearables but set up can be cumbersome and if performed in a running lab, it can be very costly for the user. The AiKYNETIX platform is a downloadable app that has a $10 monthly subscription and can be set up with only a tripod.

Within six months of launching, the technology was being tested in a professional lab to track 360 different running conditions. AiKINETIX is a finalist of CodeLaunch accelerator and has moved into phase 1 with America’s Seed Fund powered by the National Science Foundation.

AiKYNETIX has experts and consultants with experience at NASA, Major League Baseball, and European Soccer League.

The AiKYNETIX team is raising seed funding to help to accelerate the development of the app to go to a wider market. The team will also host a showcase of the technology at the grand opening of the fitness center at The Ion this month.

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Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

Texas space co. takes giant step toward lunar excavator deployment

Out of this world

Lunar exploration and development are currently hampered by the fact that the moon is largely devoid of necessary infrastructure, like spaceports. Such amenities need to be constructed remotely by autonomous vehicles, and making effective devices that can survive the harsh lunar surface long enough to complete construction projects is daunting.

Enter San Antonio-based Astroport Space Technologies. Founded in San Antonio in 2020, the company has become a major part of building plans beyond Earth, via its prototype excavator, and in early February, it completed an important field test of its new lunar excavator.

The new excavator is designed to function with California-based Astrolab's Flexible Logistics and Exploration (FLEX) rover, a highly modular vehicle that will perform a variety of functions on the surface of the moon.

In a recent demo, the Astroport prototype excavator successfully integrated with FLEX and proceeded to dig in a simulated lunar surface. The excavator collected an average of 207 lbs (94kg) of regolith (lunar surface dust) in just 3.5 minutes. It will need that speed to move the estimated 3,723 tons (3,378 tonnes) of regolith needed for a lunar spaceport.

After the successful test, both Astroport and Astrolab expressed confidence that the excavator was ready for deployment. "Leading with this successful excavator demo proves that our technology is no longer theoretical—it is operational," said Sam Ximenes, CEO of Astroport.

"This is the first of many implements in development that will turn Astrolab's FLEX rover into the 'Swiss Army Knife' of lunar construction. To meet the infrastructure needs of the emerging lunar economy, we must build the 'Port' before the 'Ship' arrives. By leveraging the FLEX platform, we are providing the Space Force, NASA, and commercial partners with a 'Shovel-Ready' construction capability to secure the lunar high ground."

"We are excited to provide the mobility backbone for Astroport's groundbreaking construction technology," said Jaret Matthews, CEO of Astrolab, in a release. "Astrolab is dedicated to establishing a viable lunar ecosystem. By combining our FLEX rover's versatility with Astroport's civil engineering expertise, we are delivering the essential capabilities required for a sustainable lunar economy."

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This article originally appeared on CultureMap.com.

Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.

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