This week's roundup of Houston innovators includes Richard Seline of the Resilience Innovation Hub, Deanna Zhang of Tudor, Pickering, and Holt, and Brad Hauser of Soliton. Courtesy photos

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three innovators across industries recently making headlines — from resilience technology to energy innovation.

Richard Seline, co-founder at the Houston-based Resilience Innovation Hub Collaboratory

Richard Seline of Houston-based Resilience Innovation Hub joins the Houston Innovators Podcast to discuss how it's time for the world to see Houston as the resilient city it is. Photo courtesy of ResilientH20

Richard Seline says on this week's episode of the Houston Innovators Podcast, that people are exhausted and these feelings are festering into frustration and anger — and calling for change. The things that need to change, Seline says, includes growing investment and innovation in resilience solutions.

"As a fourth generation Houstonian, it's just so hard to see my hometown get hit persistently with a lot of these weather and other type of disasters," Seline says.

These unprecedented disasters — which are of course occurring beyond Houston and Texas — have also sparked a growing interest in change for insurance companies that have lost a trillion dollars on the United States Gulf Coast over the past seven years, Seline says. Something has got to change regarding preparation and damage mitigation. Read more and stream the podcast.

Deanna Zhang, director of energy technology at Houston-based Tudor, Pickering, Holt & Co.

Deanna Zhang of Tudor, Pickering, Holt & Co. writes a response to the energy crisis that occured in Texas in February. Photo courtesy of TPH

Deanna Zhang specializes in energy tech, and what she witnessed from February's winter weather was basically an epic fail caused by a myriad of issues.

"But it's oversimplifying to say that the only solution to preventing another situation like this is continued or increased reliance on the oil and gas industry," she writes in a guest article for InnovationMap. "What last week ultimately demonstrated was the multitude of technology solutions that needs to scale up to provide us with the best energy reliability and availability." Read more.

Brad Hauser, CEO of Soliton

Houston-based Soliton can use its audio pulse technology to erase scars, cellulite, and tattoos. Photo courtesy of Soliton

A Houston company has created a technology that uses sound to make changes in human skin tissue. Soliton, led by Brad Hauser, is using audio pulses to make waves in the med-aesthetic industry. The company, which is licensed from the University of Texas on behalf of MD Anderson, announced that it had received FDA approval earlier this month for its novel and proprietary technology that can reduce the appearance of cellulite.

"The original indication was tattoo removal," Hauser says. "The sound wave can increase in speed whenever it hits a stiffer or denser material. And tattoo ink is denser, stiffer than the surrounding dermis. That allows a shearing effect of the sound wave to disrupt that tattoo ink and help clear tattoos."

According to Hauser, the team then turned to a second application for the technology in the short-term improvement in the appearance of cellulite. With the use of the technology, patients can undergo a relatively pain-free, 40- to 60-minute non-invasive session with no recovery time. Read more.

What winter storm Uri ultimately demonstrated was the multitude of technology solutions that needs to scale up to provide us with the best energy reliability and availability. Photo by Lynn in Midtown via CultureMap

Houston expert: Winter storm Uri's devastation should be a reminder to prioritize innovative energy solutions

guest column

Texas has landed itself in the middle of a fierce debate following what's been considered one of the worst winter storm in recent history for the state.

Uri wreaked havoc as it rolled through regions that were wholly unprepared for the sudden temperature drops, single digit wind chills, and unusual precipitation (e.g. thundersnow in Galveston). Rolling power outages and water shortages affected more than 4.5 million Texans. Businesses like grocery stores and restaurants — unable to wash food or sanitize equipment or even turn on the lights, —closed throughout the ordeal, leaving many families without food, water, or power.

For most, this was an unprecedented experience. The majority of catastrophes in Texas are in the form of warm weather events like floods, hurricanes, or tornadoes, which means that even if power is lost, freezing is rarely an issue. Uri turned this upside down. ERCOT's failure to provide reliable energy for days on end led to families sleeping in devastatingly cold temperatures, further water shortage due to municipal water facilities failing, carbon monoxide deaths, disruption in vaccine rollouts, hospitals overrun with people needing to charge essential medical equipment, and much more. Uri highlighted in harrowing detail the domino effect that energy (and lack thereof) has on everything around it.

A single source of ERCOT's failure is hard to pinpoint. The cold led to production shut-ins, exacerbating the existing natural gas supply shortage and resulted in the RRC prioritizing "direct-to-consumer" natural gas delivery (i.e. to residences, hospitals, schools, etc.) over natural gas for the grid. Iced-over gas lines disrupted this flow even further. Freezing temperatures shut off some wind turbines and solar panels (if they were not already covered in snow). Coal and nuclear plants in Texas also shut down due to frozen instruments and equipment.

Thrown into sharp relief was the importance of consumer access to natural gas and other fossil fuels like propane. Most homes that had completely electrified (including my own) were ill-prepared to heat their homes without access to the grid or backup generators. Residential and community solar did little to alleviate this problem in many cases as lower technology configurations either froze, were not able to capture enough energy from a low-light environment, or were covered in snow. Having access to gas for heating or a propane stove was a lifeline for most folks.

But it's oversimplifying to say that the only solution to preventing another situation like this is continued or increased reliance on the oil and gas industry.

What last week ultimately demonstrated was the multitude of technology solutions that needs to scale up to provide us with the best energy reliability and availability.

It wasn't enough for our grid to have five potential generation sources – they all failed in different ways. But what if we incorporated more geothermal, which is more cold-weather resistant? What if we upgraded our solar panels to all have trackers or heating elements to prevent snow accumulation? What if our grid had access to larger scale energy storage? What if consumers had more access to off-grid distributed energy systems like generators, residential solar, geothermal pumps, or even just really large home batteries? What if we had predictive solutions that were able to detect when the non-winterized equipment would fail, days before they did? What if we could generate power from fossil fuels without dangerous emissions like carbon monoxide?

All of these technologies and more are being created and developed in our energy innovation ecosystem today, and many in Houston. What we're building towards is diversity of our energy system — but not just diversity of source — which is often the focus – but diversity of energy transportation, energy delivery, and energy consumption. Energy choice is about being able to, as a consumer, have a variety of options available to you such that in extenuating circumstances like winter storms or other catastrophes, there is no need to depend on any single configuration.

In a state like Texas, which is not only the largest oil and gas producer but also the largest wind energy producer and soon to be home to the largest solar project in the US, innovation should and will happen across all energy types and systems. Uri can teach us about the importance of the word all and how critical it is to encourage startups and technology development to develop stronger energy choice. Texas is the perfect home for all of this — and our state's rather embarrassing failure around Uri should be exactly the kind of reminder we need to keep encouraging this paradigm.

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Deeana Zhang is the director of energy technology at Houston-based Tudor, Pickering, Holt & Co.

This week's roundup of Houston innovators includes Deanna Zhang of Tudor, Pickering, & Holt Co., Sarma Velamuri of Luminare, and Amy Chronis of Deloitte. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three innovators recently making headlines — from health tech founders to the new GHP chair.

Deeana Zhang, director of energy technology at Tudor, Pickering, Holt & Co.

Deanna Zhang of Tudor, Pickering, Holt & Co. joined the Houston Innovators Podcast to discuss 2020's effect on the energy transition — and what that meant for startups. Photo courtesy of TPH

Deanna Zhang looks closely at the energy innovation market and, well, last year was extremely enlightening about the energy industry and where tech is taking it. She joined the Houston Innovators Podcast last week to discuss some of the 2020 trends and observations she had — and what that means for 2021.

"The energy transition saw a huge uptick in 2020 — and there's a lot of implications of that from what pilots are getting commercialized and what companies are getting more funding," says Zhang. "All around it was hugely disruptive — but hugely beneficial I think to the energy transition." Click here to read more and stream the episode.

Dr. Sarma Velamuri, CEO of Luminare

A Houston health tech startup has launched a COVID-19 vaccine management tool. Image via luminaremed.com

As great as it was to be able to begin distributing the life-saving COVID-19 vaccine, the logistics of the two-dose process was a nightmare. Dr. Sarma Velamuri, CEO of Luminare, thought he could innovate a solution. His new platform, Innoculate (a mash-up of "innovate" and "inoculate"), enables organizations like public health departments, fire departments, school systems, and businesses to manage high-volume vaccination initiatives.

"Usually when you hear news of a new batch of vaccines headed your way, there is dread at the management and distribution overhead. Not anymore," Velamuri says in a release. "Innoculate will help streamline the vaccination process in the fight against COVID-19 and allow for hundreds of thousands of people to get vaccines easily." Click here to read more.

Amy Chronis, Greater Houston Partnership's 2021 chair and the Houston managing partner at Deloitte

Houston, we have a perception problem — but the Greater Houston Partnership's new chair, Amy Chronis, is here to fix it. Photo courtesy Deloitte/AlexandersPortraits.com

Hey Houston, it's time to speak up — a little louder for the people in the back. That's what Amy Chonis, 2021 chair for the Greater Houston Partnership, wants you to know, and that it's important for business leaders across the city to take the initiative about how great Houston is.

"We just don't brag enough about how much the city has changed and its trajectory," she tells InnovationMap.

While Houston has long been innovative in the health, space, and energy industries, it has a perception problem. Recently, Chronis addressed some of these concerns in her address at the GHP's 2021 Annual Meeting. She joined InnovationMap for an interview to zero in on how the business community can work to change this perception problem and continue to grow its innovation and tech community. Click here to read the Q&A.

Deanna Zhang of Tudor, Pickering, Holt & Co. joined the Houston Innovators Podcast to discuss 2020's effect on the energy transition — and what that meant for startups. Photo courtesy of TPH

Houston expert: 2020 was 'hugely disruptive — but hugely beneficial' for the energy transition

HOUSTON INNOVATORS PODCAST EPISODE 69

In 2020, the economy was hit with a double whammy of sorts — from a devastating pandemic to an unprecedented drop in oil prices — and that has meant that the energy transition is happening at a faster pace than ever.

Deeana Zhang, director of energy technology at Tudor, Pickering, Holt & Co., joined the Houston Innovators Podcast this week to discuss what she observed throughout the year as she worked closely with energy tech businesses.

"Because it was such a disruptive year, everyone — from the commercial and business side to the consumer side — has rethought how they are using and thinking about energy," she says on the show. "It was the first time that you saw such a mass disruption of energy demand, and that rolls through the entire ecosystem."

The effect touched all four corners of the industry in some way, and it forced all major energy players to be more intentional with their business strategy — especially when it comes to the role they play within the energy transition.

"The energy transition saw a huge uptick in 2020 — and there's a lot of implications of that from what pilots are getting commercialized and what companies are getting more funding," says Zhang. "All around it was hugely disruptive — but hugely beneficial I think to the energy transition."

Environmental, social and corporate governance, which has been growing in importance to investors and company leadership for several years now, also got a spur from 2020. ESG has been propelled by activism and consumer choice, Zhang says, but now investors are now forced to be more cognizant than ever.

"What's the investor responsibility to society as a whole? It's going beyond economics — what's your social and environmental responsibility? I think a lot of that expansion of responsibility is what's driving ESG," she says. "That's going to trickle down corporations and companies as they think about what is their expanded responsibility."

Zhang, who works closely with energy startups, also observed a profound effect when it came to capital and new business.

"A lot of companies say numbers go down in 2020, but the exceptions to that were companies that had a strong energy transition angle. Those companies were able to reposition themselves to ... counteract what was going on in the market in general," Zhang says. "From a capital raising standpoint, it was also really challenging. A lot of funds put a hold on investing in new companies and even some to their existing portfolio."

Investment came back toward the second half of the year, but there was a new level of caution, she says, and this is something startups saw happening across the country.

Zhang discusses more about what she saw happen last year for energy technology — as well as what that means for 2021 — on the episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

From fossil fuels to clean and sustainable energy, here's what experts postulate the industry will look like in 2050. Natalie Harms/InnovationMap

Overheard: Experts weigh in on what the energy industry will look like in 2050 at Houston summit

Crystal ball

There are a lot of things up in the air within the energy industry when you look at the next 40 years — clean energy, regulation regarding fossil fuels, carbon footprint, and so much more.

At the Society of Petroleum Engineers' inaugural SPE Dot Energy Leadership Summit, the big question was what does 2050 look like for the industry. Tasked with the discussion were three energy leaders — Deanna Zhang, energy tech investment banking associate at TudorPickering Holt & Co., Lees Rodionov, vice president of Global Stewardship at Schlumberger, and David R. Hall, managing director of Hall Labs — on a panel moderated by Gabriella Rowe, CEO of Station Houston.

The panel, which took place on August 15 at MATCH, discussed all the variables and what their potential theories are for how time will change oil and gas. Of course, no one knows for sure. If they did, they wouldn't be sharing it, would they?

"It's very hard I think to capture all the things that will play out by 2050, and honestly, if I knew with any amount of certainty what would happen, I wouldn't be talking about it in public," Zhang says. "I'd be in a basement somewhere, making a company that would make a trillion dollars."

Fair enough. Here are some other overheard quotes from the discussion in case you missed it.

“I think we’ll face the fact that we’ve got to be totally clean and solve the emissions problem and do a complete full cycle. It’ll mean lots of innovation, but I certainly see the capability to get it done.”

David R. Hall, managing director of Hall Labs.

“When it comes to bridging the efficiency debate and the green and clean debate, that will be something that by 2050 we will have bridged.”

— Deanna Zhang, energy tech investment banking associate at Tudor Pickering Holt & Co. Currently, she says the industry is split. "Right now we are trying to optimize for two objectives. The industry is divided."

“I think that one of the challenges actually is that it’s an idea of ‘us and them,’ and energy is a ‘we.’ Everyone has a role to play.”

Lees Rodionov, vice president of Global Stewardship at Schlumberger. She emphasized that it's the energy industry — oil and gas is just one part, and it's where there's a lot of money. O&G does have opportunities for carbon neutral development.

“The opportunity for the oil and gas industry is to recognize the problems and then announce solutions itself. If the industry doesn’t, regulators will."

— Hall says on moving the industry toward a cleaner, greener future.

“In 50 years, we’ll find a way to survive, but it won’t be the same quality of life.”

— Zhang, when asked about the worst case scenario if the industry doesn't make big changes. She cites urbanization and a greater wealth gap as some things to expect.

"Stop saying 'oil and gas.' It's 'energy.'"

— Rodionov, when asked about bridging the gap between renewables and fossil fuels.

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”