Texas' first decacorn and more top innovation news for January 2025

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Colossal is reportedly Texas' first decacorn. Photo courtesy Colossal Biosciences

Editor's note: It's time to look back at the top innovation headlines from January 15-30. Here are the most-read InnovationMap stories for the second half of January 2025, from the birth of Texas' first decacorn to an exciting collaboration between researchers at top Texas universities.

1. Biosciences startup becomes Texas' first decacorn after latest funding

Colossal Bioscience.Texas bioscience company Colossal is reportedly the state's first decacorn. Courtesy photo

A Dallas-based biosciences startup whose backers include millionaire investors from Austin and Dallas has reached decacorn status — a valuation of at least $10 billion — after hauling in a series C funding round of $200 million, the company announced this month. Colossal Biosciences is reportedly the first Texas startup to rise to the decacorn level. Continue reading.

2. Houston investor on why 2025 will be the year of exits

Samantha Lewis of Mercury joins the Houston Innovators Podcast. Photo courtesy of Mercury

Samantha Lewis will be the first to admit that the past few years have been tough on startups and venture capital investors alike. However, as she explains on the Houston Innovators Podcast, the new year is expected to look very different. Continue reading.

3. Houston private equity firm beats target on first investment fund

The Sallyport Partners Fund focuses on investments in founder- and family-owned businesses, corporate carve-outs and startups in various industries. Photo via Getty Images

Houston-based private equity firm Sallyport has raised $160 million for its first investment fund, exceeding the target amount by $10 million. The Sallyport Partners Fund focuses primarily on investments in founder- and family-owned businesses, corporate carve-outs and startups in various industries. Continue reading.

4. Texas universities develop innovative open-source platform for cell analysis

Baylor College of Medicine, Texas A&M and University of Houston researchers have designed SPACe, a new open-source image analysis platform. Photo via Getty Images

What do labs do when faced with large amounts of imaging data? Powerful cloud computing systems have long been the answer to that question, but a new riposte comes from SPACe. That’s the name of a new open-source image analysis platform designed by researchers at Baylor College of Medicine, Texas A&M University and the University of Houston. Continue reading.

5. The Ion names new coworking partner for Houston innovation hub

Coworking company Industrious replaces WeWork-owned Common Desk at The Ion. Photo via thecommondesk.com

Rice University subsidiary Rice Real Estate Co. has tapped coworking company Industrious as the new operator of the Ion’s 86,000-square-foot coworking space in Midtown. Industrious replaces WeWork-owned Common Desk in that role. Continue reading.

The Ion expanded its coworking space — and more top stories from the week. Photo via iondistrict.com

Ion grows coworking footprint, Cart.com returns HQ to Houston, and more top stories

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Editor's note:Another week has come and gone, and it's time to round up the top headlines from the past few days. Trending Houston tech and startup articles on InnovationMap included the Ion growing its coworking space, Cart.com moving its headquarters back to Houston, and more.

Houston-founded unicorn logistics company returns HQ to the Bayou City

It's a homecoming for this Texas unicorn. Photo via cart.com

While originally founded in Houston in 2020, Cart.com has called Austin home for the past two years. Now, the scaling software company is coming home.

Cart.com, a tech company providing commerce and logistical solutions for businesses, announced today that its corporate headquarters has returned to Houston amid its rapid growth.

“I couldn’t be happier to bring Cart.com back home to Houston as we continue to revolutionize how merchants sell and fulfill products to meet customers anywhere they are,” Cart.com Founder and CEO Omair Tariq says in a news release. “The idea for Cart.com was born in Houston and we’ve always maintained a strong local presence with the majority of our executive team and board based here. As our customer mix increasingly moves upmarket and our own needs evolve, I’m confident Houston has what we need as we look towards the next stage of Cart.com’s growth story.” Read more.

Growing femtech company chooses Houston for first out-of-state expansion

After growing in Chicago and raising funding, Partum Health selected Houston to expand its femtech platform. Photo via Getty Image

A startup dedicated to comprehensive pregnancy, birth and postpartum care has expanded from its Chicago birthplace to Houston.

Last summer, Partum Health raised $3.1 million in seed funding, which makes it possible for the company to begin a nationwide expansion. That begins in Space City.

“We looked at states where there is work to do on outcomes for maternal health. Texas rose to the top and Houston, in many ways is fairly close to Chicago, our home city. The really thriving healthcare ecosystem attracted us as well,” CEO and Co-Founder Meghan Doyle tells InnovationMap.Read more.

Coworking concept delivers 28,000-square-foot expansion in the Ion

The Ion now officially has more coworking space. Photo via thecommondesk.com

The coworking space in the Ion has increased by 50 percent thanks to a recent expansion project.

Dallas-based Common Desk has officially delivered on its project to expand the coworking space in the Ion that it originally opened on the second floor two years ago. Now, coworkers have access to a total of 86,400 square feet of space, including newly opened space on the fourth floor. The company has agreed to a 10-year commitment to the Ion with the expansion.

“This expansion of Common Desk at The Ion was designed specifically to complement the existing amenities and serve remote and hybrid work styles," Austin Gauley, head of design at Common Desk says in the news release. "There's a variety of video conferencing room types—from multiple individual private rooms, to a large group presentation-style room—all equipped with state-of-the-art technology that is also user-friendly. Read more.

Houston founders named winners for 2023 Entrepreneur of the Year awards

Gaurab Chakrabarti and Sean Hunt were originally named regional winners in this year's competition this summer along with nine other Houston entrepreneurs. Photos via solugen.com

Houston’s Gaurab Chakrabarti and Sean Hunt, the founders of the transformative chemical manufacturing company Solugen, have been named EY’s US National Award winners for Entrepreneur of the Year.

Solugen, also recently named a finalist in the 2023 Houston Innovation Awards, is an environmentally friendly approach that relies on smaller chemical refineries that helps in reducing costs and transportation-related emissions. Some of their noted accomplishments includes innovations like the proprietary reactor, dubbed the Bioforge, which is a carbon-negative molecule factory and manufacturing process produces zero wastewater or emissions compared with traditional petrochemical refineries.The Bioforge uses a chemienzymatic process in converting plant-sourced substances into essential materials that can be used instead of fossil fuels. Read more.

4 Houston life science startups secure over $40M in CPRIT funding

Four Houston startups have received over $40 million in funding from a Texas organization. Photo via Getty Images

Four Houston bioscience startups have collected nearly $43 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT).

The four startups, the amount and purpose of each grant, and some background information about each company are rounded up here.

The Ion now officially has more coworking space. Photo via thecommondesk.com

Coworking concept delivers 28,000-square-foot expansion in the Ion

move in ready

The coworking space in the Ion has increased by 50 percent thanks to a recent expansion project.

Dallas-based Common Desk has officially delivered on its project to expand the coworking space in the Ion that it originally opened on the second floor two years ago. Now, coworkers have access to a total of 86,400 square feet of space, including newly opened space on the fourth floor. The company has agreed to a 10-year commitment to the Ion with the expansion.

“This expansion of Common Desk at The Ion was designed specifically to complement the existing amenities and serve remote and hybrid work styles," Austin Gauley, head of design at Common Desk says in the news release. "There's a variety of video conferencing room types—from multiple individual private rooms, to a large group presentation-style room—all equipped with state-of-the-art technology that is also user-friendly.

"We doubled down on outfitting our space with more art from local artists and creative works that reflect the community," Gauley continues. "Altogether, we've built a range of workspace solutions to fuel creativity and productivity."

Common Desk has grown in Houston over the past few years, opening its sixth location earlier this year. The Ion location is home to many Houston startups and entrepreneurs. Passes, desks, and offices are all available at the Ion's coworking space.

"Common Desk's expansion at the Ion is a testament to the community and experience we've created here," Jan Odegard, executive director at the Ion, says in the release. "Accessibility to connections and an array of amenities and resources continues to drive traffic for us, and we are thrilled to welcome the anticipated growth of new like-minded individuals coming to the Ion daily."

Passes, desks, and offices are all available at the Ion's coworking space. Photo via thecommondesk.com

Houston's coworking space is growing. Photo courtesy of The Cannon

Houston sees growth in coworking space, rises in national ranks for 2023

growing and flexing

Houston continues to grow its coworking space across the city — and the progress is notable just between the first and second quarters of 2023, a recent report shows.

When it comes to coworking space growth, Houston saw an increase of 16 percent between June and March of 2023, reports CoworkingCafe. This stat means Houston outpaced the national average, which is 10 percent. Houston, which now has a reported 208 coworking and flex office space facilities, edged out Boston in the overall rankings of cities based on number of coworking spaces.

Houston ranks No. 7 now behind Manhattan, Los Angeles, Washington, D.C., Chicago, Dallas - Fort Worth, and Atlanta, respectively.

When it came to the amount of space coworkers in Houston have, the Bayou City reported "an equally impressive expansion in terms of square footage," reads the report, "the market logged the highest increase in this metric and ended at more than 4,160,000 square feet of coworking space."

Nationally, coworking space totals 120 million square feet, which is a 6 percent increase between Q1 and Q2 and about 1.74 percent of the total office space nationwide.

While Houston saw growth in its coworking space, half of the top 25 markets for coworking have seen decreases in 2023 so far. Philadelphia, Seattle, the Bay Area, and Denver saw a decreased square footage average, but this trend isn't reflected when it comes to the number of coworking spots, which "likely equates to an increased focus on smaller coworking spaces across the nation," the report finds.

"With falling property values in some cities and rising interest rates, the commercial real estate industry is at a crossroads," says Doug Ressler, business intelligence manager at Yardi Matrix, in the report. "Many companies still aren't certain the number of employees who will be in their physical office space in the near or long term. That has led to firms doing smaller projects with startups, like pilot tests, instead of larger-scale purchases."

In January, Texas coworking company Common Desk announced its sixth Houston-area location. Common Desk also shared that it's expanding in the Ion last December, and that construction is ongoing.

The Cannon, a Houston-based coworking company, its latest locations in Fish Creek and The Woodlands, which is a partnership with Amegy Bank.

Stephanie Tsuru joins this week's Houston Innovators Podcast to share her growth plans for 2023. Photo via LinkedIn

Houston founder shares expansion plans for female-focused coworking

houston innovators podcast episode 169

Stephanie Tsuru didn't know much about coworking when she decided to jump headfirst into creating SheSpace.

On this week's episode of the Houston Innovators Podcast, Tsuru, founder and CEO of SheSpace, explains that she saw an need for a place for women — entrepreneurs, independent contractors, remote workers, etc. — to congregate and collaborate. So, she filled that need.

"The idea wasn't about coworking — it was a place to bring women together so that they didn't have to sit by themselves in a coffee shop," she says on the show.

Tsuru opened the membership-based space with her daughter-in-law Katie in November of 2020, and has already expanded to support its growing membership. In August 2021, SheSpace added an additional 1,500 square feet. Now, the company has 250 women in its network, whether they rent a private office, hotdesk, or just attend for events — something Tsuru says was created based on interest from potential members.

"We had so many people who wanted to be a part of the community — so we started a social networking group," she says.

SheSpace was designed very intentionally, Tsuru explains on the podcast. Everything from the colors on the walls to the parking and surrounding retail access was intentional.

"Women have a lot of stuff on their plate," she says, explaining how SheSpace has a gas station, a grocery store, a nail salon, and more within the same retail property. "We don't get our stuff done in an office complex."

SheSpace has a busy year ahead. While the Heights-area location will be SheSpace's flagship and where programming will continue to be held, Tsuru says she has plans to open a satellite location to accommodate a growing membership and Houston's sprawl.

"We are looking at satellite areas for more offices, workspace, and meeting rooms," she says. "We'll make a decision and have a location this year."

She shares more about what she's accomplished with SheSpace in its first two years — as well as what's next on the podcast. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


Both the city and state appear on a new report on best places for coworking. Photo via Getty Images

Report: Houston, Texas rank as top locations for coworking space

where to work

Attention all Houston-based remote workers, small business owners, and startups — if you're looking for flexible office space, you're in the right place.

Both the city and state have landed on CoworkingCafe's list of the best places for coworking in the country. With 652 reported coworking spots, Texas ranks as the No. 2 state — behind California 1,188 coworking spots and ahead of Florida's 629 and New York's 589 offices.

Houston ranks as eighth best metro for coworking with 208 coworking facilities. The Dallas-Fort Worth area ranked a few spots ahead of the Bayou City, coming in at No. 5 with 261 coworking spots. Austin also makes the top 2 with a reported 97 coworking spots, earning the No. 19 spot.

Data via coworkingcafe.com

According to the report, the area looked into included 15 cities within the Houston metro. The majority of the coworking properties —154 of the 208 identified — are located in Houston proper. Sugar Land has over 10 coworking spots, with the rest of the properties scattered across the greater Houston area in Katy, Spring, The Woodlands, etc.

Houston has followed the overall trend of increased remote workers, though not to the extreme other cities and states are seeing, according to the study. Per a Statista report, the number of people working in coworking spaces today has more than tripled since 2015. Houston's remote workers increased to 16 percent in 2021 from 4 percent in 2019.

"Even though Houston is already an established working hub with great job opportunities, it is also one of the cities with the lowest change in the share of remote workers," the report reads. "The change, however, still accounts for a notable outcome."

Earlier this year, a Seattle-based human resources company named Karat conducted their own report on the most attractive metros for remote workers within tech. In that 2022 study, Houston ranked No. 6 just ahead of No. 7 Austin. Last year, Houston ranked as No. 2 and Dallas at No. 9, but that North Texas metro fell off the top 10 for 2021. Pittsburgh maintained its top spot on this list year over year.

"Last year we took our first look at the rapidly expanding remote software engineer hiring landscape. As more organizations shifted to remote or hybrid working models we had started to see significantly improving candidate performance outside of the more-established tech hubs," writes Patrick Wu, data analyst at Karat, in a blog post. "Today, as even more top tech companies commit to hiring remote software engineers, we’re taking a look at how this landscape has continued to evolve."

The full ranking of CoworkingCafe's report is below.

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United breaks ground on $177 million facility and opens tech center at IAH

off the ground

United Airlines announced new infrastructure investments at George Bush Intercontinental Airport as part of the company’s ongoing $3.5 billion investment into IAH.

United broke ground on a new $177 million Ground Service Equipment (GSE) Maintenance Facility this week that will open in 2027.

The 140,000-square-foot GSE facility will support over 1,800 ground service vehicles and with expansive repair space, shop space and storage capacity. The GSE facility will also be targeted for LEED Silver certification. United believes this will provide more resources to assist with charging batteries, fabricating metal and monitoring electronic controls with improved infrastructure and modern workspaces.

Additionally, the company opened its new $16 million Technical Operations Training Center.

The center will include specialized areas for United's growing fleet, and advanced simulation technology that includes scenario-based engine maintenance and inspection training. By 2032, the Training Center will accept delivery of new planes. This 91,000-square-foot facility will include sheet metal and composite training shops as well.

The Training Center will also house a $6.3 million Move Team Facility, which is designed to centralize United's Super Tug operations. United’s IAH Move Team manages over 15 Super Tugs across the airfield, which assist with moving hundreds of aircraft to support flight departures, remote parking areas, and Technical Operations Hangars.

The company says it plans to introduce more than 500 new aircraft into its fleet, and increase the total number of available seats per domestic departure by nearly 30%. United also hopes to reduce carbon emissions per seat and create more unionized jobs by 2026.

"With these new facilities, Ground Service Equipment Maintenance Facility and the Technical Operations Training Center, we are enhancing our ability to maintain a world-class fleet while empowering our employees with cutting-edge tools and training,” Phil Griffith, United's Vice President of Airport Operations, said in a news release. “This investment reflects our long-term vision for Houston as a critical hub for United's operations and our commitment to sustainability, efficiency, and growth."

Trailblazing Houston leaders and more innovation news to know right now

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Editor's note: It's time to look back at the top Houston innovation and business news for the second half of March 2025. InnovationMap's top stories include female founders in the Inc. spotlight, an inaugural list of top local business and civic leaders, Harris County's population boom, and more. Read more below.

1. Texas robotics co. begins new search for missing Malaysia Airlines flight 370

Ocean Infinity will begin a new search for MH370. Ocean Infinity/Facebook

Malaysia’s government has given final approval for a Texas-based marine robotics company to renew the search for Malaysia Airlines Flight 370, which is believed to have crashed in the southern Indian Ocean more than a decade ago.

Cabinet ministers agreed to terms and conditions for a “no-find, no-fee” contract with Texas-based Ocean Infinity to resume the seabed search operation at a new 5,800-square-mile site in the ocean, Transport Minister Anthony Loke said in a statement. Ocean Infinity will be paid $70 million only if wreckage is discovered. Continue reading.

2. 5 Houston female founders land on coveted Inc. 500 list

Sassie Duggleby, Margo Jordan, Stephanie Murphy, Emily Cisek and Nina Magon were named to Inc.'s Female Founders 500 list for 2025. Photos courtesy the company's websites and social media pages.

Five Houston female founders have been recognized by Inc. Magazine for their innovations and for leading their industries forward.

The women were named to Inc.'s Female Founders 500 list, which features female entrepreneurs based in the U.S. The group attracted approximately $9 billion in 2024 revenue and $10.6 billion in funding, according to Inc.

“Female founders know what struggle is, but they’re also experts of improvisation, adaptability, and creativity. The women featured on this year’s list exemplify these qualities," Diana Ransom, Inc. executive editor said in a release. "Through times of uncertainty, their unwavering dedication and steadfast leadership are not only inspiring but vital to driving progress.” Continue reading.

3. Harris County booms with 3rd biggest population in U.S.

Harris County booms with 3rd biggest population in U.S.

Harris County now boasts a population of more than 5 million. Photo via Getty Images

Newly released U.S. Census Bureau data has revealed Harris County became the third most populous county nationwide in 2024, and it had the highest year-over-year growth rate from 2023.

The new population report, published this month, estimated year-over-year population data from 2023 to 2024 across all 3,144 U.S. counties, and 387 metro areas. Harris County's numeric growth rate outpaced all other U.S. counties from July 1, 2023 to July 1, 2024, the report found. The Census Bureau estimated Harris County's population grew by 105,852 people year-over-year, bringing the total population to 5,009,302 residents. That's around a 2.16 percent growth rate. Continue reading.

4. Houston lab develops AI tool to improve neurodevelopmental diagnoses

A new AI tool from a Baylor College of Medicine Lab could help better diagnose specific types of autism spectrum disorder, epilepsy and developmental delay disorders. Photo via Getty Images.

One of the hardest parts of any medical condition is waiting for answers. Speeding up an accurate diagnosis can be a doctor’s greatest mercy to a family. A team at Baylor College of Medicine has created technology that may do exactly that.

Led by Dr. Ryan S. Dhindsa, assistant professor of pathology and immunology at Baylor and principal investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, the scientists have developed an artificial intelligence-based approach that will help doctors to identify genes tied to neurodevelopmental disorders. Continue reading.

5. Houston's top 25 business and civic leaders named by local organization

The Center for Houston’s Future will celebrate its first Top 25 Business/Civic Leadership Forum Alumni group all year, kicking off with an event this week. Photo via Getty Images

As part of its 25th anniversary celebrations, the Center for Houston’s Future has named its first-ever group of Top 25 Business/Civic Leadership Forum Alumni, including energy transition CEOs and legendary craft brewery founders.

The group was selected from among 1,400 alumni of the Center for Houston's Future's Leadership Forum, which hosts two cohorts per year, bringing together leaders from across industries to focus on issues critical to the long-term success of Greater Houston. Continue reading.

UH study uncovers sustainable farming methods for hemp production

growth plan

A new University of Houston study of hemp microbes can potentially assist scientists in creating special mixtures of microbes to make hemp plants produce more CBD or have better-quality fibers.

The study, led by Abdul Latif Khan, an assistant professor of biotechnology at the Cullen College of Engineering Technology Division, was published in the journal Scientific Reports from the Nature Publishing Group. The team also included Venkatesh Balan, UH associate professor of biotechnology at the Cullen College of Engineering Technology Division; Aruna Weerasooriya, professor of medicinal plants at Prairie View A&M University; and Ram Ray, professor of agronomy at Prairie View A&M University.

The study examined microbiomes living in and around the roots (rhizosphere) and on the leaves (phyllosphere) of four types of hemp plants. The team at UH compared how these microorganisms differ between hemp grown for fiber and hemp grown for CBD production.

“In hemp, the microbiome is important in terms of optimizing the production of CBD and enhancing the quality of fiber,” Khan said in a news release. “This work explains how different genotypes of hemp harbor microbial communities to live inside and contribute to such processes. We showed how different types of hemp plants have their own special groups of tiny living microbes that help the plants grow and stay healthy.”

The study indicates that hemp cultivation can be improved by better understanding these distinct microbial communities, which impact growth, nutrient absorption, stress resilience, synthesis and more. This could help decrease the need for chemical inputs and allow growers to use more sustainable agricultural practices.

“Understanding these microorganisms can also lead to more sustainable farming methods, using nature to boost plant growth instead of relying heavily on chemicals,” Ahmad, the paper’s first author and doctoral student of Khan’s, said the news release.

Other findings in the study included higher fungal diversity in leaves and stems, higher bacterial diversity in roots and soil, and differing microbiome diversity. According to UH, CBD-rich varieties are currently in high demand for pharmaceutical products, and fiber-rich varieties are used in industrial applications like textiles.

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