Support Houston startups by shopping local this holiday season. Photos courtesy

The holidays are fully upon us, and in the spirit of giving, why not give a little business to local startups as you shop for friends and family this year?

Browse this year's roundup of Houston startup-created gift ideas below, and then click here to check out last year's gift ideas too for eight more options for you.

Low-carb treats from ChipMonk Baking

Give the gift of healthy desserts with ChipMonk Baking. Photo via chipmonkbaking.com

Houstonians David Downing and Jose Hernandez were tired of having such limited options when it came to finding healthy dessert alternatives. So, they founded ChipMonk Baking, a local, mail-order bakery that creates treats using monk fruit and allulose, a low-calorie (0.4 calories per gram) rare sugar that's found naturally in foods such as raisins, dried figs, and kiwi. Hernandez began developing ChipMonk's recipes to satisfy his taste for cookies after being diagnosed with type-2 diabetes.

An online business, ChipMonk offers every snacks from cookies and bites to mixes and sweeteners. There are also a few bundles to choose from as well as a free, downloadable holiday cookbook

Skin-healthy athletic wear from Élastique

Emeline Kuhner-Stout, founder of Élastique Athletics, wanted to create a product that was easy to wear and benefitted lymphatic health. Photo courtesy of Élastique Athletics

Moms know how to make the most of their time, and that's exactly how Emeline Kuhner-Stout came across the idea for Élastique Athletics, a clothing line that promotes skin health and reduces cellulite.

"We did some research, and found that the best way to improve the appearance of your skin and move those fluids — because the cause [of cellulite] is really about those fluids that get trapped under your skin and cause a lot more negative effects other than skin appearance," Kuhner-Stout previously told InnovationMap.

She learned that exercise is the best move for improving lymphatic drainage, and another option is to do it manually through massaging and with compression. After around five years of research and development, Kuhner-Stout was able to release her first product for Élastique Athletics — a pair of leggings that have MicroPerle™ micro-massage beads in the compression leggings to massage the skin when worn.

Now, Élastique has three "wellnesswear" products available online.

Support local with Sesh Coworking

Sesh's gift sets are available for pick-up or delivery. Photo via girlsesh.com

Sesh Coworking is a space founded for women, by women, and that focus extends to the company's in-store and online market. Located in Montrose, Sesh opened its doors in February and was founded by Maggie Segrich and Meredith Wheeler to fill a need in the coworking sector.

"We as women show up in our work lives as a whole person. We don't compartmentalize and forget about all the other things happening in our lives," Wheeler previously told InnovationMap. "We wanted a space that reflected that and embraced it."

While the market supports local female-owned business year round, Sesh has some special items for the holidays. The company has produced a 2020 Holiday Haute List to help users find the perfect gift as well as some gift bundles for the working women of the world. These sets and more are available on Sesh's online store.

Stylish sanitizers from Cobalt

Cobalt's gift set comes with a bottle of each of the company's three FDA-approved cleaning products. Photo via cobaltclean.com

This year's pandemic inspired new products and companies aplenty, and one of them here in Houston is Cobalt founded by Houstonians Molly Voorhees and Christina Milligan. Their hand sanitizing and surface cleaning products blend the importance of cleanliness and safety with the added value of accessibility and a refined appearance.

As working parents of young children, the two women wanted to create a line of sanitizing products that boosted their confidence in the safety of their environments amid a pandemic and that they'd be proud to pull out of their purse on short notice.

"Cleaning products are in your bathroom or are in an ugly looking bottle or the back of our restaurant in massive chemical containers. There is really nothing for the on-the-go market," Voorhees says.

The company sells six FDA-approved sanitizers, sprays, keychains, and to-go kits that eliminate 99.9 percent of bacteria and viruses in easy to access, personal-sized, contemporary bottles, ranging from $14 to $30. The products are designed to be free of harsh, alcoholic odors and come in scents like peppermint and bubble gum.

The gift set, which is available online for $50, includes a bottle of hand sanitizer, surface spray, and mask refresher.

Humidity-conscious women's workwear from Cotidie

Cotidié's fabrics are lightweight and moisture wicking — similar to exercise clothing — making the pieces conducive to the Houston heat and humidity. Lauren Marek/Cotidié

Other than during Houston's brief winter, rocking a professional wardrobe is tough in humidity that is so iconic to Houston. Local entrepreneur Kristina Haag founded Cotidié to design clothes with this struggle in mind.

"With Cotidié, it is all about the functionality of the clothing," Haag previously told InnovationMap. "It is more traditional items, but the use of technical fabrics is our differentiating factor."

The online retailer, which launched in June 2019, offers dresses, jackets, pants, skirts, and tops, ranging between $60 and $200 in price. The fabrics, sourced from Italy and Taiwan, provide breathable comfort, along with an elastic, structured fit for a more tailored look. All items are moisture wicking and machine washable.

"Everything we use on the line is athletic technical fabric that you would typically find in workout attire, but I've repurposed these fabrics to use in a contemporary womenswear line," Haag tells InnovationMap. "I wanted to create a more foundational capsule clothing collection that women can draw their own inspiration from."

The full collection is available online, as are gift cards.

Bonus: 8 more gift ideas from Houston startups

From after-alcohol relief to a smart pillbox, these Houston-founded companies have innovative holiday gifts to offer. Images via Instagram

Here are eight more ideas for gifts made by Houston startups. Click here,

Matthew Costello, Kristina Haag, and Greg Wright are this week's Houston innovators to know. Courtesy photos

3 Houston innovators to know this week

who's who

It's the penultimate Monday of 2019, which means it's also the penultimate roundup of Houston innovators to know this week.

Today's featured innovators include an entrepreneur revolutionizing the maritime shipping industry, a fashion designer striving for comfort in Houston's long summers, and a startup advocate shining a spotlight on cybersecurity.

Matthew Costello, co-founder and CEO of Voyager

Matthew Costello Voyager

Houston-based Voyager, co-founded by Matthew Costello, has created a software solution for inefficient communication practices of the maritime shipping industry. Photo courtesy of Voyager

While in business school, Matthew Costello could not kick the thought of all the inefficiencies within the maritime shipping industry. He asked a friend, Bret Smart, to help him look into some of the logistical communications issues within the industry. The two co-founders of Houston-based Voyager started asking some questions for all the different parties involved in shipping across seas.

"The data we got back was pretty alarming," Costello says on this week's episode of the Houston Innovators Podcast. "It basically showed that whoever you speak to in the maritime industry, people are spending about 40 percent of their day on what we would consider low-value, low-complexity tasks." Read more and stream the podcast here.

Kristina Haag, founder of Cotidíe

Kristina Haag worked a corporate job that required her to run around Houston. She thought of her new fashion line out of wanting stylish clothes conducive to Houston's climate. Lauren Marek/Cotidié

Houston is a humid subtropical climate — the majority of the year brings hot and sticky weather. Local entrepreneur Kristina Haag found herself struggling to find traditional clothing that is comfortable in the Texas heat, so she created it herself.

"With Cotidié, it is all about the functionality of the clothing," says Haag, founder of the clothing line Cotidié. "It is more traditional items, but the use of technical fabrics is our differentiating factor."

The online retailer, which launched in June 2019, offers pieces specifically tailored for women who are up against Houston's hot and muggy climate. Read more here.

Greg Wright, founder of Hatch Pitch

Houston-based Hatch Pitch will host two competitions in spring of 2020 — one marks the return of the competition to the Bayou City. Photo courtesy of Hatch Pitch

For eight years, Greg Wright has been organizing a SXSW pitch competition in Austin for startups from around the world that are using technology to improve life. In 2020, Wright is bringing Houston-based Hatch Pitch back into the Bayou City — a goal he's had for a while — for a new cybersecurity-focused event.

"Many people know us as being associated with Austin and SXSW, but not many people know us as being based in Houston," Wright tells InnovationMap. "There's been a big push to bring Hatch back to Houston, and what we've been struggling with is finding the right vehicle."

After Hatch Pitch Summit returns to Austin for its ninth year on March 16, Cyber Hatch will be hosted by the annual Houston Cyber Summit on April 28. Read more here.

Cotidié's fabrics are lightweight and moisture wicking — similar to exercise clothing — making the pieces conducive to the Houston heat and humidity. Lauren Marek/Cotidié

Local entrepreneur designs fashionable clothes with Houston's heat and humidity in mind

h-town workwear

Houston is a humid subtropical climate — the majority of the year brings hot and sticky weather. Local entrepreneur Kristina Haag found herself struggling to find traditional clothing that is comfortable in the Texas heat, so she created it herself.

"With Cotidié, it is all about the functionality of the clothing," says Haag, founder of the clothing line Cotidié. "It is more traditional items, but the use of technical fabrics is our differentiating factor."

The online retailer, which launched in June 2019, offers pieces specifically tailored for women who are up against Houston's hot and muggy climate.

The line offers dresses, jackets, pants, skirts, and tops, ranging between $60 and $200 in price. The fabrics, sourced from Italy and Taiwan, provide breathable comfort, along with an elastic, structured fit for a more tailored look. All items are moisture wicking and machine washable. The line uses three different fabrics: LunAir, 88 percent polyester and 12 percent spandex; SolaSmooth, 73 percent nylon and 27 percent elastane; and StellaForm, 59 percent nylon and 41 percent elastane.

"Everything we use on the line is athletic technical fabric that you would typically find in workout attire, but I've repurposed these fabrics to use in a contemporary womenswear line," Haag tells InnovationMap. "I wanted to create a more foundational capsule clothing collection that women can draw their own inspiration from."

Haag, originally from Houston, studied history and business at Rice University before moving to London to attend the British School of Fashion. Following a few years of work at a London-based fashion PR firm, she returned to Texas. Haag was working a corporate job that required extensive job-site visits.

"I thought, how is there not more stylish women's clothing on the market that is comfortable and functional," says Haag.

The name Cotidié, which means "daily" or "every day," encompasses Haag's desire to create clothing that can be worn at work, for travel, on weekends, and more. Haag was determined to find comfortable professional clothing that held up in Houston's heat and humidity and created Cotidié to bridge the gap between technical performance wear and business attire, introducing a new kind of clothing for stylish women on the go.

Kristina Haag worked a corporate job that required her to run around Houston. She thought of her new fashion line out of wanting stylish clothes conducive to Houston's climate. Lauren Marek/Cotidié

Haag worked for over a year testing different fabrics and designing each piece to blend feminine style with technical performance. Haag works with Sew Pro Production, an apparel manufacturer based in Houston to develop the pieces.

For Cotidié's fall and winter line, which launched in October 2019, Haag adapted the pieces for cooler weather as the temperature shifts.

Haag plans to expand the marketing of Cotidié to a national scale in the next year. The company currently has two employees and has plans to begin fundraising efforts in 2020. The company currently ships internationally.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."