XSpace, an innovative commercial real estate company, has partnered with three Houston firms to help grow its footprint. Rendering via xspacegroup.com

Texas-based XSpace Group has brought onboard three partners from the Houston area to ramp up the company’s national expansion.

The new partners of XSpace, which sells high-end multi-use commercial condos, are KDW, Pyek Financial and Welcome Wilson Jr. Houston-based KDW is a design-build real estate developer, Katy-based Pyek offers fractional CFO services and Wilson is president and CEO of Welcome Group, a Houston real estate development firm.

“KDW has been shaping the commercial [real estate] landscape in Texas for years, and Pyek Financial brings deep expertise in scaling businesses and creating long‑term value,” says Byron Smith, founder of XSpace. “Their commitment to XSpace is a powerful endorsement of our model and momentum. With their resources, we’re accelerating our growth and building the foundation for nationwide expansion.”

The expansion effort will target high-growth markets, potentially including Nashville, Tennessee; Orlando, Florida; and Charlotte and Raleigh, North Carolina.

XSpace launched in Austin with a $20 million, 90,000-square-foot project featuring 106 condos. The company later added locations on Old Katy Road in Houston and at The Woodlands Town Center. A third Houston-area location is coming to the Design District.

XSpace condos range in size from 300 to 3,000 square feet. They can accommodate a variety of uses, such as a luxury-car storage space, a satellite office, or a podcasting studio.

“XSpace has tapped into a fundamental shift in how entrepreneurs and professionals want to use space,” Wilson says. “Houston is one of the best places in the country to innovate and build, and XSpace’s model is perfectly aligned with the needs of this fast‑growing, opportunity‑driven market.”

City of Houston has entered into an agreement with Texas Southern University to develop an aviation program at the Houston Spaceport. Photo via fly2houston.com

Houston Spaceport launches $12M expansion for leading space tech co.

to the moon

Houston will get one step closer to the moon, as the Houston Spaceport at Ellington Airport (EFD) has announced an expansion of the lease for Intuitive Machines, the Houston space tech leader dedicated to furthering lunar exploration.

On July 15, the City of Houston announced passage of Amendment 1, which would add three acres of commercial space for Intuitive Machines at the spaceport and a $12 million infrastructure expansion. Approved by the city council and Mayor John Whitmire, the expansion will include new production, testing and support facilities. The amendment extends the current lease for Intuitive Machines from 20 years to 25 years.

"I want to shout out to Intuitive Machines about everything they’re doing at the Houston Spaceport. It’s exciting to see them expand. We’re starting to reach a critical mass out there — more and more aerospace companies want to be at the Spaceport because that’s where innovation is happening,” said Fred Flinkinger, who represents District E on the Houston City Council. “It’s a great sign of momentum, and we’re proud to have them here in Houston."

Intuitive Machines was the first commercial tenant for the Houston Spaceport when it moved into the facility in August 2016. Founded by Stephen Altemus, Kam Ghaffarian, and Tim Crain in 2013, the company holds three contracts with the National Aeronautics and Space Administration (NASA) to deliver payloads to the lunar surface. In 2023, the company opened its doors in Houston with a 105,572-square-foot Lunar Production and Operations Center that contains research and development labs, clean rooms, mission control centers, and a spacecraft assembly floor.


Intuitive Machines landed Odysseus on the moon in February 2024, the first privately owned soft lunar landing ever and the first soft landing since 1972.

The Houston Spaceport is owned and operated by the City of Houston and Houston Airports, who have an eye of keeping the city a prime name in space exploration. As "Houston" was the first word spoken on the moon when Apollo 11 landed in 1969, lunar exploration in particular has a soft place in the heart of the metropolis formerly known as Space City.

“This agreement reinforces Houston’s leadership in space innovation,” said Jim Szczesniak, director of aviation for Houston Airports. “We’re building infrastructure and supporting the next era of lunar and deep space exploration, right here at Houston Spaceport. This partnership represents the forward-thinking development that fuels job creation and drives long-term economic growth.”
The new program will work with commercial spaceflight crews to bring back crucial research to one database. Photo via NASA/Unsplash

Houston organization launches the first commercial spaceflight medical research program

out of this world health care

With commercial space activity reaching cruising altitude, a Houston space health research organization has introduced a new program to create a centralized database.

The Translational Research Institute for Space Health, or TRISH, at Baylor College of Medicine announced a unique program that will work with commercial spaceflight providers and their passengers. The EXPAND — Enhancing eXploration Platforms and Analog Definition — Program will collect information and data from multiple space flights and organize it in one place. TRISH selected TrialX to build the centralized database.

As a partner to the NASA Human Research Program, the Houston-based organization's mission is to reduce health risks for astronauts and uncover advances for terrestrial healthcare, according to a news release.

"The space environment causes rapid body changes. This can help us understand how we humans react to and overcome stress. Ensuring that space explorers remain healthy pushes us to invent new approaches for early detection and prevention of medical conditions," says Dorit Donoviel, executive director at TRISH, in the release. "Studying a broad range of people in space increases our knowledge of human biology. TRISH's EXPAND program will leverage opportunities with commercial spaceflight providers and their willing crew to open up new research horizons."

The new collaborative program is meant to address the challenges that humans face on space missions — early detection and treatment of medical conditions, protection from radiation, mental health, team dynamics, and more. TRISH has been working on these challenges since its inception.

"This ground-breaking research model is only possible because everyone — scientists, commercial spaceflight companies, and passengers - recognizes the importance of space health research, and what we can learn by working together," says Dr. Emmanuel Urquieta, TRISH's chief medical officer, in the release.

EXPAND's first collaboration is the Inspiration4 mission, which is launching on September 15. The all-civilian crew will perform a variety of TRISH-supported human health experiments during their time in orbit.

"Shorter commercial space flights like Inspiration4 have similarities to early NASA Artemis missions," says Jimmy Wu, TRISH's senior biomedical engineer. "This allows TRISH an opportunity to test new health and performance technologies for future NASA astronauts."

The potential impact of innovation with this new centralized database and biobank is profound, says James Hury, TRISH's deputy director and chief innovation officer.

"The EXPAND database has the flexibility to seamlessly take in multiple types of data from different flight providers in order to create a repository that can integrate information," says Hury in the release. "A centralized, standardized research database and biobank will increase access to knowledge about human health for the global research community."

KBR signed a Space Act Agreement with NASA's Johnson Space Center to provide private astronaut training in NASA facilities. Photo via NASA.gov

Houston tech company gets green light from NASA to train commercial astronauts

space tech

For 60 years, Houston-based KBR has supported NASA's astronauts. Now, though a recently signed Space Act Agreement, KBR will also be providing its human spaceflight operation services to commercial companies.

"KBR has pioneered space travel for more than half a century. We will leverage our domain expertise to assist private astronauts with their human spaceflight activities," says Stuart Bradie, KBR President and CEO, in a news release.

The arrangement will include KBR training private astronauts on NASA property — it's the only agreement of its kind. KBR will train for space tasks like operating onboard of the International Space Station, routine operational tasks, health and performance checks, responding to emergencies, and more.

"This historic agreement is a testament to KBR's long standing partnership with NASA. We will continue to work together to propel NASA's mission to fuel a low-Earth orbit economy and advance the future of commercial space," Bradie continues in the release.

Earlier this week, Axiom Space, a Houston-based space tech startup, announced it was selected to design a commercial space flight habitat to be attached to the ISS. KBR is among Axiom's professional partners on the project.

Image---Axiom-modules-connected-to-ISSKBR is one of Axiom Space's partners on its new NASA-sanctioned ISS project. Photo via AxiomSpace.com

The Axiom project includes plans to replace the ISS with a commercially operated space station. The targeted launch date for the commercial destination module is set for late 2024.

Both the Axiom and KBR agreements with NASA are in line with a shift toward commercialization within the space industry. Last June, NASA released its plan to introduce marketing and commercial opportunities to the ISS — with financial expense being a main factory.

"The agency's ultimate goal in low-Earth orbit is to partner with industry to achieve a strong ecosystem in which NASA is one of many customers purchasing services and capabilities at lower cost," reads the release online.

In an interview with InnovationMap last July, NASA Technology Transfer Strategist Steven Gonzalez explains that opening up the space industry to commercial opportunities allows for NASA to focus on research. The government agency doesn't need to worry about a return on investment, like commercial entities have to.

"With the commercial market now, people keep talking about it being a competition, but in reality we need one another," Gonzalez says. "We have 60 years of history that they can stand on and they are doing things differently that we're learning from."

Reda Hicks create GotSpot — a digital tool that helps connect people with commercial space with people who need it. Courtesy of GotSpot

How a Houston corporate lawyer is making short-term commercial space easier to find

Featured Innovator

It only took a natural disaster for Reda Hicks to make her startup idea into a reality.

"I had been thinking on what it would be like to help people find space to do business in and how businesses find a way to stay in business a long time," Hicks says. "But, I was afraid of the tech."

Hicks, who has practiced law for almost 15 years, wanted to create a website that allows for people with commercial space — a commercial kitchen, conference room, spare desks, etc. — to list it. Then, space seekers — entrepreneurs, nonprofits, freelancers, etc. — can rent it. When Hurricane Harvey hit, Hicks was kicking herself for not acting on her idea sooner.

"It was really Harvey and having so many people desperate to find space for emergency purposes that made me realize there are so many contexts in which people need space right away for something specific," she says. "Certainly the primary user is the entrepreneur trying to grow their business, but there are so many other reasons why a community would need better access to the space it already has."

GotSpot Inc. soft launched last June with 17 listings. The company now has 37 and new listings are generated daily. Hicks has won two pitch competitions and is headed to Silicon Valley in March for Women's Startup Labs.

"In 2019, we're going to be working with local business partners, like the chambers. We'll be working on building out a team. I'll be hitting the road in March headed to Silicon Valley for Women's Startup Labs."

She spoke with InnovationMap on her career and what it takes to be a mom, a wife, a corporate lawyer, and a startup founder — all rolled into one.

InnovationMap: Did you always want to be an entrepreneur?

Reda Hicks: I feel like I kind of grew up the way a lot of small town, lower middle class kids do. The options you're aware of were either people you know or what you see on TV. Growing up there were no people in my life who were entrepreneurs. Even as a professional, it never even occurred to me. It's more about seeing a problem I wanted to be solved more than I just wanted to own my own business.

IM: How does GotSpot work?

RH: I have two types of users. One is the person who has the space — a shop on Main Street or conference rooms you're not using — and you're looking for a way to monetize that space. We call those our spot holders. It's so easy to go on the platform and create your profile and generate a listing. On the other side, I have spot seekers who can go on the site and search the available listings they are interested in booking for hours, days, or weeks at a time. It's not fully automated right now. The booking process and the calendar is all ran by me. In the next two to three months, we'll have it up and running like that, and it will feel a lot like Airbnb.

It's strictly website based right now, and I did that intentionally. Spot holders don't want to build their profile on their phones. But the site is mobile friendly.

IM: What are some early challenges you faced?

RH: My biggest challenge honestly was having a problem and wanting to solve it, but not knowing where to start — especially because I'm not a tech person. From a subject matter and contacts perspective, I felt like I had the resources. My first question was, "Who can I call?" It's a testament to Houston. No one I called said no. We talk often about how we are a new ecosystem, but we also are an extremely generous and connected city. What I see and what I hope continues is that we are an ecosystem that builds by leveraging all the awesome that's already here.

IM: Where did the name come from?

RH: I reached out to three military spouses I know and asked them to help. We spitballed a bunch of ideas. I wanted it to be simple and clear, because so many brands come up with a cute name but it takes forever to explain. We literally pulled out a thesaurus and thought of all the words that mean "space" and "finding," and that exercise is where GotSpot came from.

IM: What makes GotSpot different from anything else out there?

RH: There are a few different marketplaces out there for commercial space, but they tend to be more specialized. But another way GotSpot is different is I'm being very intentionally community driven. I look at GotSpot as your digital sidekick to grow your business — whether it's helping you pay your rent by creating a new way to make money or helping you say yes to more opportunities. But I'm also collecting information on how that same space can be used for the community. Harvey is a part of my origin story. Every time I onboard a new space, I ask if you are willing to be activated in case of an emergency, and if so, how can you be used — industrial space or washer and dryers. In other communities, there are other kind of emergencies. And, I also know half the nonprofits in Texas don't keep their own space any more, because donors don't want their money to go to overhead. I ask my space holders if they are willing to give a discount to nonprofits.

IM: What expertise from your career as a corporate lawyer do you bring to your startup career?

RH: A couple of things. I've spent my whole career working in large corporations. I really understand how the inside of a company works and how to think creatively and mitigate risks. It's so interesting because when I start talking to people about GotSpot, I have to be honest about how this is my first entrepreneurial experience. So when I say that, people tell me, "well, you're going to have to have really good counsel." And I tell them, "well, actually, I am really good counsel." The demeanor of who I'm talking to — whether it's an adviser or a potential investor — fundamentally shifts.

IM: What's been the most challenging aspect of still working full time and having a family?

RH: Probably the thing that has been the most challenging has been access to resources as a female founder. What I mean by that is there's all this great programing and things happening around town are always in the evening. It's hard to make happy hours. What I'm starting to see is more programing is a diversity of when that programing is available. I'm privileged in that I can do my job from anywhere during the day, but if all of the golden opportunities are on a weekday at 5 pm, my mommy duties win. Always.

IM: How has Houston been as a home for your startup?

RH: I think one aspect of the secret sauce is how open and can do of a city it is. It is not the traditional thing you think of when you think of startups. But we know better. In the startup space, what I love, is that I am kind of seeing it like we're building the plane as we're flying it. We have some people who have been around for a long time, but even some of our incubators are startups on their own. We have the ability, since we're still building it now, to have an ecosystem that reflects our city. We have a long ways to go, there are still some things that we are working through — capital is one of them.

------

Portions of this interview have been edited.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

Texas foundation makes massive $180M donation to Galveston hospital

historic gift

The University of Texas Medical Branch in Galveston (UTMB) has accepted a staggering $130 million grant from the Sealy & Smith Foundation, which, combined with the $50 million that the foundation donated in 2025 to establish the Department of Cardiovascular Medicine, is the largest bequest in UTMB history.

The grant will go to grow cardiovascular imaging, diagnosis, and treatment at UTMB by establishing an inpatient cardiovascular hub on the sixth floor of Jennie Sealy Hospital. In honor of the donation, the department is being renamed the Sealy Heart and Vascular Institute.

“The Sealy & Smith Foundation has a long history of investing in initiatives that transform health care for the people of Galveston and beyond,” said John Kelso, president of The Sealy & Smith Foundation Board of Directors. “We believe the Sealy Heart & Vascular Institute has the potential to redefine cardiovascular care in our region by bringing together exceptional physicians, advanced technology, innovative research and a commitment to improving patient outcomes. This additional investment reflects our confidence in UTMB’s vision and our belief that the Institute will have a lasting impact for generations to come.”

The Sealy & Smith Foundation was established in 1922 by John Sealy II and his sister Jennie Sealy Smith. Bolstered by the Sealy fortune built on shipping, oil, banking, and railroads, the Foundation has donated more than $1.2 billion to UTMB over the last century, linking the family legacy to healthcare, teaching, and research. It was John Sealy Sr. who contributed the initial $50,000 to build a hospital on the island, which opened right alongside the new medical school created by the state legislator in what was then Texas's largest and most economically powerful city.

Since then, the Foundation has helped grow UTMB into a world-class hospital. The cardiovascular care especially is well-regarded, making the 2025 Newsweek/Statista List of America's Best Hospitals.

“This extraordinary investment reflects The Sealy & Smith Foundation’s unwavering commitment to improving health and advancing medical excellence,” said Dr. Jochen Reiser, UTMB president and CEO of the UTMB Health System. “The partnership between UTMB and The Sealy & Smith Foundation is very strong. Built on generations of shared vision and trust, it continues to redefine what an academic health system can achieve. Together, we are building one of the nation’s premier cardiovascular programs integrating exceptional patient care, groundbreaking research, innovation and world-class education to improve the lives of patients throughout Texas and beyond.”

---

This article originally appeared on CultureMap.com.

UTHealth Houston team joins NASA initiative to protect border drinking water

water watch

Climate change means far more to public health than living with hotter days. Transformations in our weather are contributing to challenges in accessing safe drinking water in some communities.

One of the most dire situations is along the US–Mexico border. The National Aeronautics and Space Administration (NASA) is seeking to address that issue with its Water Quality Applications program. An 11-researcher project led by a UTHealth Houston School of Public Health faculty member has been selected to participate.

“Drinking water is one of the most fundamental public health protections, but producing safe drinking water involves a delicate balance,” Yun Hang, assistant professor of environmental and occupational health sciences, said in a news release. Her team’s proposal was one of 93 that were submitted for funding through NASA’s Research Opportunities in Space and Earth Sciences (ROSES)-2025 program.

This is the first time that NASA has worked with a team devoted to water quality applications. The group, which includes researchers from across the nation, will use satellite observations of Earth, as well as hydrologic modeling, to potentially anticipate and act on water quality conditions as they change. Challenges addressed over the course of the three-year program, which kicked off in June, might include problems with water quality due to climate variability and increased pressure on water resources.

Hang’s team will focus on a pair of borderlands: Paso del Norte and the Rio Grande Valley.

“Working closely with El Paso Water ensures that our research addresses real operational needs while helping utilities better prepare for climate-related water quality changes and continue providing safe drinking water to communities across the Texas border region,” Hang added in the release.

She and the team will use data gathered by NASA on both past and future Earth-observing missions, which will allow them to track environmental changes that may affect source water quality. Combined with past water treatment records and hydrologic models, the team will also utilize artificial intelligence to develop predictive tools that aim to stop issues before they become larger hurdles to water safety.

Another one of the project’s goals is to create visualization tools and source water summaries that can be utilized by those without scientific expertise. The tools will be produced in English and Spanish to further broaden their accessibility.

The hope is that the materials made by the team will also go far beyond the border, with protocols that can be adapted or adopted by other areas dealing with water quality issues.