Houston organization launches the first commercial spaceflight medical research program

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The new program will work with commercial spaceflight crews to bring back crucial research to one database. Photo via NASA/Unsplash

With commercial space activity reaching cruising altitude, a Houston space health research organization has introduced a new program to create a centralized database.

The Translational Research Institute for Space Health, or TRISH, at Baylor College of Medicine announced a unique program that will work with commercial spaceflight providers and their passengers. The EXPAND — Enhancing eXploration Platforms and Analog Definition — Program will collect information and data from multiple space flights and organize it in one place. TRISH selected TrialX to build the centralized database.

As a partner to the NASA Human Research Program, the Houston-based organization's mission is to reduce health risks for astronauts and uncover advances for terrestrial healthcare, according to a news release.

"The space environment causes rapid body changes. This can help us understand how we humans react to and overcome stress. Ensuring that space explorers remain healthy pushes us to invent new approaches for early detection and prevention of medical conditions," says Dorit Donoviel, executive director at TRISH, in the release. "Studying a broad range of people in space increases our knowledge of human biology. TRISH's EXPAND program will leverage opportunities with commercial spaceflight providers and their willing crew to open up new research horizons."

The new collaborative program is meant to address the challenges that humans face on space missions — early detection and treatment of medical conditions, protection from radiation, mental health, team dynamics, and more. TRISH has been working on these challenges since its inception.

"This ground-breaking research model is only possible because everyone — scientists, commercial spaceflight companies, and passengers - recognizes the importance of space health research, and what we can learn by working together," says Dr. Emmanuel Urquieta, TRISH's chief medical officer, in the release.

EXPAND's first collaboration is the Inspiration4 mission, which is launching on September 15. The all-civilian crew will perform a variety of TRISH-supported human health experiments during their time in orbit.

"Shorter commercial space flights like Inspiration4 have similarities to early NASA Artemis missions," says Jimmy Wu, TRISH's senior biomedical engineer. "This allows TRISH an opportunity to test new health and performance technologies for future NASA astronauts."

The potential impact of innovation with this new centralized database and biobank is profound, says James Hury, TRISH's deputy director and chief innovation officer.

"The EXPAND database has the flexibility to seamlessly take in multiple types of data from different flight providers in order to create a repository that can integrate information," says Hury in the release. "A centralized, standardized research database and biobank will increase access to knowledge about human health for the global research community."

KBR signed a Space Act Agreement with NASA's Johnson Space Center to provide private astronaut training in NASA facilities. Photo via NASA.gov

Houston tech company gets green light from NASA to train commercial astronauts

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For 60 years, Houston-based KBR has supported NASA's astronauts. Now, though a recently signed Space Act Agreement, KBR will also be providing its human spaceflight operation services to commercial companies.

"KBR has pioneered space travel for more than half a century. We will leverage our domain expertise to assist private astronauts with their human spaceflight activities," says Stuart Bradie, KBR President and CEO, in a news release.

The arrangement will include KBR training private astronauts on NASA property — it's the only agreement of its kind. KBR will train for space tasks like operating onboard of the International Space Station, routine operational tasks, health and performance checks, responding to emergencies, and more.

"This historic agreement is a testament to KBR's long standing partnership with NASA. We will continue to work together to propel NASA's mission to fuel a low-Earth orbit economy and advance the future of commercial space," Bradie continues in the release.

Earlier this week, Axiom Space, a Houston-based space tech startup, announced it was selected to design a commercial space flight habitat to be attached to the ISS. KBR is among Axiom's professional partners on the project.

Image---Axiom-modules-connected-to-ISSKBR is one of Axiom Space's partners on its new NASA-sanctioned ISS project. Photo via AxiomSpace.com

The Axiom project includes plans to replace the ISS with a commercially operated space station. The targeted launch date for the commercial destination module is set for late 2024.

Both the Axiom and KBR agreements with NASA are in line with a shift toward commercialization within the space industry. Last June, NASA released its plan to introduce marketing and commercial opportunities to the ISS — with financial expense being a main factory.

"The agency's ultimate goal in low-Earth orbit is to partner with industry to achieve a strong ecosystem in which NASA is one of many customers purchasing services and capabilities at lower cost," reads the release online.

In an interview with InnovationMap last July, NASA Technology Transfer Strategist Steven Gonzalez explains that opening up the space industry to commercial opportunities allows for NASA to focus on research. The government agency doesn't need to worry about a return on investment, like commercial entities have to.

"With the commercial market now, people keep talking about it being a competition, but in reality we need one another," Gonzalez says. "We have 60 years of history that they can stand on and they are doing things differently that we're learning from."

Reda Hicks create GotSpot — a digital tool that helps connect people with commercial space with people who need it. Courtesy of GotSpot

How a Houston corporate lawyer is making short-term commercial space easier to find

Featured Innovator

It only took a natural disaster for Reda Hicks to make her startup idea into a reality.

"I had been thinking on what it would be like to help people find space to do business in and how businesses find a way to stay in business a long time," Hicks says. "But, I was afraid of the tech."

Hicks, who has practiced law for almost 15 years, wanted to create a website that allows for people with commercial space — a commercial kitchen, conference room, spare desks, etc. — to list it. Then, space seekers — entrepreneurs, nonprofits, freelancers, etc. — can rent it. When Hurricane Harvey hit, Hicks was kicking herself for not acting on her idea sooner.

"It was really Harvey and having so many people desperate to find space for emergency purposes that made me realize there are so many contexts in which people need space right away for something specific," she says. "Certainly the primary user is the entrepreneur trying to grow their business, but there are so many other reasons why a community would need better access to the space it already has."

GotSpot Inc. soft launched last June with 17 listings. The company now has 37 and new listings are generated daily. Hicks has won two pitch competitions and is headed to Silicon Valley in March for Women's Startup Labs.

"In 2019, we're going to be working with local business partners, like the chambers. We'll be working on building out a team. I'll be hitting the road in March headed to Silicon Valley for Women's Startup Labs."

She spoke with InnovationMap on her career and what it takes to be a mom, a wife, a corporate lawyer, and a startup founder — all rolled into one.

InnovationMap: Did you always want to be an entrepreneur?

Reda Hicks: I feel like I kind of grew up the way a lot of small town, lower middle class kids do. The options you're aware of were either people you know or what you see on TV. Growing up there were no people in my life who were entrepreneurs. Even as a professional, it never even occurred to me. It's more about seeing a problem I wanted to be solved more than I just wanted to own my own business.

IM: How does GotSpot work?

RH: I have two types of users. One is the person who has the space — a shop on Main Street or conference rooms you're not using — and you're looking for a way to monetize that space. We call those our spot holders. It's so easy to go on the platform and create your profile and generate a listing. On the other side, I have spot seekers who can go on the site and search the available listings they are interested in booking for hours, days, or weeks at a time. It's not fully automated right now. The booking process and the calendar is all ran by me. In the next two to three months, we'll have it up and running like that, and it will feel a lot like Airbnb.

It's strictly website based right now, and I did that intentionally. Spot holders don't want to build their profile on their phones. But the site is mobile friendly.

IM: What are some early challenges you faced?

RH: My biggest challenge honestly was having a problem and wanting to solve it, but not knowing where to start — especially because I'm not a tech person. From a subject matter and contacts perspective, I felt like I had the resources. My first question was, "Who can I call?" It's a testament to Houston. No one I called said no. We talk often about how we are a new ecosystem, but we also are an extremely generous and connected city. What I see and what I hope continues is that we are an ecosystem that builds by leveraging all the awesome that's already here.

IM: Where did the name come from?

RH: I reached out to three military spouses I know and asked them to help. We spitballed a bunch of ideas. I wanted it to be simple and clear, because so many brands come up with a cute name but it takes forever to explain. We literally pulled out a thesaurus and thought of all the words that mean "space" and "finding," and that exercise is where GotSpot came from.

IM: What makes GotSpot different from anything else out there?

RH: There are a few different marketplaces out there for commercial space, but they tend to be more specialized. But another way GotSpot is different is I'm being very intentionally community driven. I look at GotSpot as your digital sidekick to grow your business — whether it's helping you pay your rent by creating a new way to make money or helping you say yes to more opportunities. But I'm also collecting information on how that same space can be used for the community. Harvey is a part of my origin story. Every time I onboard a new space, I ask if you are willing to be activated in case of an emergency, and if so, how can you be used — industrial space or washer and dryers. In other communities, there are other kind of emergencies. And, I also know half the nonprofits in Texas don't keep their own space any more, because donors don't want their money to go to overhead. I ask my space holders if they are willing to give a discount to nonprofits.

IM: What expertise from your career as a corporate lawyer do you bring to your startup career?

RH: A couple of things. I've spent my whole career working in large corporations. I really understand how the inside of a company works and how to think creatively and mitigate risks. It's so interesting because when I start talking to people about GotSpot, I have to be honest about how this is my first entrepreneurial experience. So when I say that, people tell me, "well, you're going to have to have really good counsel." And I tell them, "well, actually, I am really good counsel." The demeanor of who I'm talking to — whether it's an adviser or a potential investor — fundamentally shifts.

IM: What's been the most challenging aspect of still working full time and having a family?

RH: Probably the thing that has been the most challenging has been access to resources as a female founder. What I mean by that is there's all this great programing and things happening around town are always in the evening. It's hard to make happy hours. What I'm starting to see is more programing is a diversity of when that programing is available. I'm privileged in that I can do my job from anywhere during the day, but if all of the golden opportunities are on a weekday at 5 pm, my mommy duties win. Always.

IM: How has Houston been as a home for your startup?

RH: I think one aspect of the secret sauce is how open and can do of a city it is. It is not the traditional thing you think of when you think of startups. But we know better. In the startup space, what I love, is that I am kind of seeing it like we're building the plane as we're flying it. We have some people who have been around for a long time, but even some of our incubators are startups on their own. We have the ability, since we're still building it now, to have an ecosystem that reflects our city. We have a long ways to go, there are still some things that we are working through — capital is one of them.

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Portions of this interview have been edited. 

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Rice biotech accelerator appoints 2 leading researchers to team

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The Rice Biotech Launch Pad, which is focused on expediting the translation of Rice University’s health and medical technology discoveries into cures, has named Amanda Nash and Kelsey L. Swingle to its leadership team.

Both are assistant professors in Rice’s Department of Bioengineering and will bring “valuable perspective” to the Houston-based accelerator, according to Rice. 

“Their deep understanding of both the scientific rigor required for successful innovation and the commercial strategies necessary to bring these technologies to market will be invaluable as we continue to build our portfolio of lifesaving medical technologies,” Omid Veiseh, faculty director of the Launch Pad, said in a news release.

Amanda Nash

Nash leads a research program focused on developing cell communication technologies to treat cancer, autoimmune diseases and aging. She previously trained as a management consultant at McKinsey & Co., where she specialized in business development, portfolio strategy and operational excellence for pharmaceutical and medtech companies. She earned her doctorate in bioengineering from Rice and helped develop implantable cytokine factories for the treatment of ovarian cancer. She holds a bachelor’s degree in biomedical engineering from the University of Houston.

“Returning to Rice represents a full-circle moment in my career, from conducting my doctoral research here to gaining strategic insights at McKinsey and now bringing that combined perspective back to advance Houston’s biotech ecosystem,” Nash said in the release. “The Launch Pad represents exactly the kind of translational bridge our industry needs. I look forward to helping researchers navigate the complex path from discovery to commercialization.”

Kelsey L. Swingle

Swingle’s research focuses on engineering lipid-based nanoparticle technologies for drug delivery to reproductive tissues, which includes the placenta. She completed her doctorate in bioengineering at the University of Pennsylvania, where she developed novel mRNA lipid nanoparticles for the treatment of preeclampsia. She received her bachelor’s degree in biomedical engineering from Case Western Reserve University and is a National Science Foundation Graduate Research Fellow.

“What draws me to the Rice Biotech Launch Pad is its commitment to addressing the most pressing unmet medical needs,” Swingle added in the release. “My research in women’s health has shown me how innovation at the intersection of biomaterials and medicine can tackle challenges that have been overlooked for far too long. I am thrilled to join a team that shares this vision of designing cutting-edge technologies to create meaningful impact for underserved patient populations.”

The Rice Biotech Launch Pad opened in 2023. It held the official launch and lab opening of RBL LLC, a biotech venture creation studio in May. Read more here.

University of Houston archaeologists make history with Mayan tomb discovery

History in the Making

Two University of Houston archaeologists have made scientific history with the discovery of a Mayan king's tomb in Belize.

The UH team led by husband and wife scientists Arlen F. Chase and Diane Z. Chase made the discovery at Caracol, the largest Mayan archeological site in Belize, which is situated about 25 miles south of Xunantunich and the town of San Ignacio. Together with Belize's Institute of Archeology, as well as support from the Geraldine and Emory Ford Foundation and the KHR Family Fund, they uncovered the tomb of Caracol's founder, King Te K’ab Chaak. Their work used airborne light detection and ranging technology to uncover previously hidden roadways and structures that have been reclaimed by the jungle.

The tomb was found at the base of a royal family shrine. The king, who ascended the throne in 331 AD, lived to an advanced enough age that he no longer had teeth. His tomb held a collection of 11 pottery vessels, carved bone tubes, jadeite jewelry, a mosaic jadeite mask, Pacific spondylus shells, and various other perishable items. Pottery vessels found in the chamber depict a Maya ruler wielding a spear as he receives offerings from supplicants represented as deities; the figure of Ek Chuah, the Maya god of traders, surrounded by offerings; and bound captives, a motif also seen in two related burials. Additionally, two vessels had lids adorned with modeled handles shaped like coatimundi (pisote) heads. The coatimundi, known as tz’uutz’ in Maya, was later adopted by subsequent rulers of Caracol as part of their names.

 Diane Chase archaeologist in Mayan tomb Diane Z. Chase in the Mayan tomb. Photo courtesy of University of Houston

During the Classical Period, Caracol was one of the main hubs of the Mayan Lowlands and covered an area bigger than that of present-day Belize City. Populations survived in the area for at least 1,000 years before the city was abandoned sometime around 900 AD. The royal dynasty established by Te K’ab Chaak continued at Caracol for over 460 years.

The find is also significant because this was roughly when the Mexican city of Teotihuacan made contact with Caracol, leading to a long relationship of trade and cultural exchange. Cremation sites found in Caracol contain items that would have come from Teotihuacan, showing the relationship between the two distant cities.

"Both central Mexico and the Maya area were clearly aware of each other’s ritual practices, as reflected in the Caracol cremation," said Arlen F. Chase, professor and chair of Comparative Cultural Studies at the University of Houston.

“The connections between the two regions were undertaken by the highest levels of society, suggesting that initial kings at various Maya cities — such as Te K’ab Chaak at Caracol — were engaged in formal diplomatic relationships with Teotihuacan.”

The Chases will present their findings at a conference on Maya–Teotihuacan interaction hosted by the Maya Working Group at the Santa Fe Institute in New Mexico in August 2025.

 UH professors Chase make Mayan Discovery UH archaeologists Arlen F. Chase and Diane Z. Chase Photo courtesy of University of Houston

 

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This story originally appeared on CultureMap.com.

Houston palliative care company integrates with Epic platforms

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Patients and medical teams using MyChart and other Epic Systems' software will now be able to access Houston-based Koda Health's AI-enhanced end-of-life planning platform.

The Houston-based palliative care company, which was born out of the TMC's Biodesign Fellowship, has integrated its advance care planning platform with Epic, one of the most widely used electronic health record (EHR) systems in the U.S., according to a news release.

Epic estimates that more than 325 million patients have a current electronic record in its systems.

“This is a significant milestone for our mission to make advance care planning scalable, meaningful, and seamless,” Tatiana Fofanova, CEO and co-founder of Koda Health, said in the release. “By integrating into systems already used by care teams, we help eliminate friction and ensure that care delivery honors what patients truly want—especially during serious illness and at the end of life.”

The partnership will streamline processes for both patients and clinicians. Users will be able to drop advance care plans directly into the Epic charts, which will be accessible through MyChart for patients and proxies and through Epic Hyperspace/Hyperdrive for care teams. Doctors can also initiate and manage advance care plans through a simple Epic order for patients.

According to Koda Health, its platform saves an average of $10,000 to $15,000 per patient. Roughly 85 percent of users complete advance care plan documents when using the platform, which is four times the national average.

“We developed Koda to give providers the time, training, and tools to guide these critical conversations," Dr. Desh Mohan, co-founder and chief medical officer at Koda Health, added in the statement. "Our integration now makes it possible to operationalize ACP at scale—aligned with value-based care goals and clinical reality.”

The company announced a partnership with Dallas-based Guidehealth, which integrates into primary care workflows and allows providers to identify high-risk patients, coordinate care and reduce administrative burden. Guidehealth works with more than 500,000 patients

Koda Health was founded in 2020 and closed an oversubscribed seed round for an undisclosed amount last year, with investments from AARP, Memorial Hermann Health System and the Texas Medical Center Venture Fund. The company also added Kidney Action Planning to its suite of services in 2024.

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