This week's Houston innovators to know includes Jon Lambert of The Cannon, Catherine Koerner of NASA, and Colton Robey of Revere Resources. Photos courtesy

Editor's note: As we start on another week, it's time to introduce you to three movers and shakers within science, tech, and innovation in Houston. This week, we have a startup leader taking coworking online, a new NASA exec with moon-bound plans, and an entrepreneur looking out for mineral rights owners.

Jon Lambert, CEO of The Cannon

Jon Lambert, CEO of The Cannon, joins the Houston Innovators Podcast to discuss Cannon Connect and the growth of The Cannon. Photo courtesy of The Cannon

When Jon Lambert joined The Cannon as CEO, he was ready to hit the ground running to expand the coworking and entrepreneurial hub concept across Houston and beyond — and, six months in, he was doing just that. Then, a pandemic hit and he and his team were forced to rethink how to grow.

The Cannon Connect, a virtual platform that exists to recreate The Cannon community online, launched a few weeks ago. Now, Lambert is focused on developing the platform to be a tool for new markets The Cannon plans to expand into.

"[We can] bring the players of the ecosystem together inside the digital component so that we can then use those connections and that dialogue to then determine the right time and place to do the physical hub development," Lambert says, adding that the these pre-pandemic conversations have picked up again. "That's where we are right now." Read more.

Catherine Koerner, manager of NASA's Orion Program

Catherine Koerner is leading the Orion Program from Houston's Johnson Space Center. Photo courtesy of NASA

Earlier this month, Catherine Koerner was named to be the new manager of NASA's Orion Program, the spacecraft that will be used for the moon-bound Artemis missions. According to a press release, Koerner's position was effective Tuesday, September 8, and will be based at NASA's Johnson Space Center in Houston.

"I'm honored to be selected as the Orion Program Manager. Orion is a key element of the agency's Artemis infrastructure, and I look forward to leading the team responsible for developing and building America's deep space human spacecraft," Koerner says in the release. "Next year we'll be launching the Artemis I test flight — a major milestone — and the first of the Artemis mission series on our way to putting the first woman and the next man on the Moon." Read more.

Colton Robey, co-founder and senior vice president of Revere Resource

Colton Robey started Revere Resources to help mineral rights owners protect themselves from bad actors. Photo courtesy of Revere Resources

A few years ago, Colton Robey helped protect his grandmother from an unfair transaction within the mineral rights space, and it led to an idea for a company. So, he teamed up with other leaders in the oil, tech, and finance industries to found Revere Resources to help landowners like his grandmother make the right decisions for their assets.

Their recently launched online resource, RevereNet, provides a dollar figure and geographic view of an owner's mineral composition along with the historical value and extensive data on wells and well locations, giving owners the information they need to get the best deal.

"Our team has all worked in different capacities at different private equity-backed mineral rights funds," says Robey. "And it all came together after somebody tried to buy my grandmother's mineral rights unjustly, it wasn't until that moment that I realized that bad actors are prevalent in the industry." Read more.

A group of Houston entrepreneurs have created a technology to advocate for mineral rights owners. Photo via Getty Images

Houston company creates platform to help protect people's mineral rights

underground business

When a landman used predatory tactics to lure his grandma into selling her mineral rights, a Houston entrepreneur stepped in, and now he's empowering landowners with knowledge and advocating for transparency for mineral buying in the oil and gas industry.

"Whether a potential seller conducts a sale with us or not, our goal is to educate families through RevereNet so they can understand what is happening in the market and protect themselves financially," says Colton Robey, co-founder and senior vice president of Revere Resources.

Robey teamed up with other leaders in the oil, tech, and finance industries to found Revere Resources to help landowners like his grandmother make the right decisions for their assets. Their recently launched online resource, RevereNet, provides a dollar figure and geographic view of an owner's mineral composition along with the historical value and extensive data on wells and well locations, giving owners the information they need to get the best deal.

"Our team has all worked in different capacities at different private equity-backed mineral rights funds," says Robey. "And it all came together after somebody tried to buy my grandmother's mineral rights unjustly, it wasn't until that moment that I realized that bad actors are prevalent in the industry."

Robey and his partners are guided by the guiding principle of transparency and honesty, even going as far as helping clients get better deals with other mineral buying companies if they beat their price.

"The data we collect allows us to gain a whole picture of the deal, so often of times we're not their natural highest bidder," says Robey. "However, we know the ins and out of the business and have helped our clients find better deals."

With RevereNet, they add a whole new layer of technology that is seldom seen in the archaic mineral rights sector, allowing landowners to check the value of their assets as easy as checking their stock portfolio.

"We believe this market is ripe for new technology," says Robey. "There are a lot of dinosaurs in this industry that need change, we collect tons of data and our online resource gives valuable information for free 365 days a week and 24/7 which definitely makes us more tech-driven than a lot of folks."

The project, which was already in production when the coronavirus pandemic changed the way we live and work, was rolled out quickly to meet landowner's immediate needs for data.

"We knew that during this time on uncertainty, a lot of people might be looking to divest," says Robey. "We're not brokers or flippers, we're long-term investors, and as mineral rights owners ourselves, I think that puts us in a different boat that other mineral rights companies."

With the successful launch of RevereNet, the team hopes to expand their efforts into new frontiers — getting this service into the hands of everyone in Texas.

"We know that only comes with people getting comfortable with learning what it is they own," says Robey. "We hope that over time we can educate landowners that can give them the confidence to manage their assets in the best financially beneficial way possible for them and their families."

The Revere Resources team wants to get all Texans on RevereNet. Photo courtesy of Revere

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”