This week's roundup of Houston innovators includes Emma Konet of Tierra Climate, Cindy Taff of Sage Geosystems, and Clemmie Martin of The Cannon. Photos courtesy

Editor's note: Welcome to another Monday edition of Innovators to Know. Today I'm introducing you to three Houstonians to read up about — three individuals behind recent innovation and startup news stories in Houston as reported by InnovationMap. Learn more about them and their recent news below by clicking on each article.

Emma Konet, co-founder and CTO of Tierra Climate

Emma Konet, co-founder and CTO of Tierra Climate, joins the Houston Innovators Podcast. Photo via LinkedIn

If the energy transition is going to be successful, the energy storage space needs to be equipped to support both the increased volume of energy needed and new energies. And Emma Konet and her software company, Tierra Climate, are targeting one part of the equation: the market.

"To me, it's very clear that we need to build a lot of energy storage in order to transition the grid," Konet says on the Houston Innovators Podcast. "The problems that I saw were really on the market side of things." Read more.

Cindy Taff, CEO of Sage Geosystems

Houston-based Sage Geosystems announced the first close of $17 million round led by Chesapeake Energy Corp. Photo courtesy of Sage

A Houston geothermal startup has announced the close of its series A round of funding.

Houston-based Sage Geosystems announced the first close of $17 million round led by Chesapeake Energy Corp. The proceeds aim to fund its first commercial geopressured geothermal system facility, which will be built in Texas in Q4 of 2024. According to the company, the facility will be the first of its kind.

“The first close of our Series A funding and our commercial facility are significant milestones in our mission to make geopressured geothermal system technologies a reality,” Cindy Taff, CEO of Sage Geosystems, says. Read more.

Clemmie Martin, chief of staff at The Cannon

With seven locations across the Houston area, The Cannon's digital technology allows its members a streamlined connection. Photo courtesy of The Cannon

After collaborating over the years, The Cannon has acquired a Houston startup's digital platform technology to become a "physical-digital hybrid" community.

Village Insights, a Houston startup, worked with The Cannon to create and launch its digital community platform Cannon Connect. Now, The Cannon has officially acquired the business. The terms of the deal were not disclosed.

“The integration of a world-class onsite member experience and Cannon Connect’s superior virtual resource network creates a seamless, streamlined environment for member organizations,” Clemmie Martin, The Cannon’s newly appointed chief of staff, says in the release. “Cannon Connect and this acquisition have paved new pathways to access and success for all.” Read more.

With seven locations across the Houston area, The Cannon's digital technology allows its members a streamlined connection. Photo courtesy of The Cannon

Houston coworking company acquires digital community platform

M&A moves

After collaborating over the years, The Cannon has acquired a Houston startup's digital platform technology to become a "physical-digital hybrid" community.

Village Insights, a Houston startup, worked with The Cannon to create and launch its digital community platform Cannon Connect. Now, The Cannon has officially acquired the business. The terms of the deal were not disclosed.

“The combined commitment to support innovation communities—large and small—is evident,” Andrew Ramirez, who served as CEO for Village Insights ahead of the acquisition, says in a news release. “Village Insights and The Cannon merged to align efforts and cultivate local, regional and global innovation communities. Combining our value propositions represents a significant leap forward for the populations that we serve.”

With seven locations across the Houston area, The Cannon's digital technology allows its members a streamlined connection.

“The Cannon’s hub network stretches from The Woodlands to Galveston and across the 13-county region, with a membership base of more than 900 companies and 3,000 employees,” Jon Lambert, CEO of The Cannon, adds. “The digital extension of our physical footprint brings comprehensive innovation and business development support to communities that need it the most. Cannon Connect’s virtual- connection capabilities stand to remarkably expand our universe of ecosystem opportunities.”

Village Insights was founded in 2020. According to the release, the acquisition began in December, and members of the Village Insights core leadership team have rolled onto new roles at The Cannon.

“The integration of a world-class onsite member experience and Cannon Connect’s superior virtual resource network creates a seamless, streamlined environment for member organizations,” Clemmie Martin, The Cannon’s newly appointed chief of staff, says in the release. “Cannon Connect and this acquisition have paved new pathways to access and success for all.”

This week's roundup of Houston innovators includes entrepreneur and author Jay Steinfeld, Clemmie Pierce Martin of Houston Exponential, and Matthew Costello of Voyager Portal. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from startup development to software — recently making headlines in Houston innovation.

Jay Steinfeld, author of Lead From The Core

Blinds.com founder Jay Steinfeld has released his new book last week. Photos courtesy of Jay Steinfeld

After Blinds.com successfully exited to Home Depot, founder Jay Steinfeld started thinking about what he wanted to do next. The entrepreneur is now on the boards of five companies and has taught at Rice University before publishing his new book, "Lead From The Core."

"The book was originally written so that the people at Blinds.com would know what got us to where we were and would use it as the foundation for continuing what that success was all about. As I began teaching and expanding my influence throughout the community nationally, I realized that there were many entrepreneurs who could learn from the same success, the techniques, the strategies," Steinfeld says. Click here to read the full interview.

Clemmie Pierce Martin, director of marketing and strategy at Houston Exponential

Clemmie Pierce Martin will oversee marketing and strategy for Houston Exponential. Photo via LinkedIn

Houston Exponential has made another new hire. Clemmie Pierce Martin has joined Houston Exponential as director of marketing and strategy. The nonprofit helps spur the growth of Houston’s innovation ecosystem.

She most recently was director of strategic partnerships and products at Houston-based startup Goodfair, which operates an online thrift store. Before that, she was head of client success at Austin-based startup Mesa Cloud, which offers a platform for tracking student progress.

Martin, who grew up in Houston and graduated from the University of Texas at Austin and Houston’s The Kinkaid School, says her new employer “sees the potential in Houston and our startup ecosystem that I’ve always felt was underserved and underrepresented nationally. I couldn’t be more excited to join a team that is working tirelessly to make sure that for founders and startups anywhere in the world, Houston is not just a choice but rather the clear choice of venue.” Click here to read more.

Matthew Costello, CEO and co-founder of Voyager Portal

Matthew Costello Voyager

Matthew Costello is the\u00a0CEO and co-founder of Voyager Portal. Photo courtesy of Voyager

Voyager Portal, a software-as-a-service platform, closed an $8.4 million series A investment round this week. The round was led by Phaze Ventures, a VC fund based in the Middle East, and included new investors — ScOp Venture Capital, Waybury Capital and Flexport. Additionally, all of Voyager's existing investors contributed to this round.

“Voyager Portal was created to significantly reduce cost, risk, and complexity when transporting bulk materials around the world,” says Matthew Costello, CEO and co-founder of Voyager, in the release. “The last two years have demonstrated just how critical shipping bulk commodities is to global markets – freight rates have increased and port congestion is at an all-time high – accelerating the demand for Voyager’s solution.” Click here to read more.

Clemmie Pierce Martin will oversee marketing and strategy for Houston Exponential. Photo via LinkedIn

Exclusive: Houston Exponential makes strategic marketing hire

innovator to know

Houston Exponential has made another new hire. Clemmie Pierce Martin has joined Houston Exponential as director of marketing and strategy. The nonprofit helps spur the growth of Houston’s innovation ecosystem.

She most recently was director of strategic partnerships and products at Houston-based startup Goodfair, which operates an online thrift store. Before that, she was head of client success at Austin-based startup Mesa Cloud, which offers a platform for tracking student progress.

Martin, who grew up in Houston and graduated from the University of Texas at Austin and Houston’s The Kinkaid School, says her new employer “sees the potential in Houston and our startup ecosystem that I’ve always felt was underserved and underrepresented nationally. I couldn’t be more excited to join a team that is working tirelessly to make sure that for founders and startups anywhere in the world, Houston is not just a choice but rather the clear choice of venue.”

Martin is a great-niece of the late President George H.W. and the late first lady Barbara Bush.

Serafina Lalany, the new executive director of Houston Exponential (HX), says Martin’s experience with startups “is an invaluable asset to the organization.”

“Her insights and experiences … couldn’t be more fitting for HX’s mission to lower the barrier of entry for early stage startups in the city,” Lalany says in a news release.

Lalany became executive director of HX in September. She had been the organization’s vice president of operations and chief of staff. Lalany succeeds Harvin Moore, who resigned this summer as president and CEO of the four-year-old nonprofit.

Earlier this month, HX named Ivery Boston III as director of inclusive innovation. He previously worked for the Miami Downtown Development Authority.

Aside from the new hires, the organization recently restructured its board of directors. The board transitioned to a more informal “convening” board, and an executive committee now oversees HX’s operations.

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Rice, Houston Methodist developing soft 'sleep cap' for brain health research

Researchers and scientists at Rice University and Houston Methodist are developing a “sleep cap” that aims to protect the brain against dementia and other similar diseases by measuring and improving deep sleep.

The project is a collaboration between Rice University engineering professors Daniel Preston, Vanessa Sanchez and Behnaam Aazhang; and Houston Methodist neurologist Dr. Timea Hodics and Dr. Gavin Britz, director of the Houston Methodist Neurological Institute and chairman of the Department of Neurosurgery.

According to Rice, deep sleep is essential for clearing waste products from the brain and nightly “cleaning cycles” help remove toxic proteins. These toxic proteins, like amyloids, can accumulate during the day and are linked to Alzheimer’s disease and other neurological issues.

Aazhang, director of the Rice Neuroengineering Initiative, and his team are building a system that not only tracks the brain’s clearing process but can also stimulate it, improving natural mechanisms that protect against neurodegeneration.

Earlier proof-of-concept versions of the caps successfully demonstrated the promise of this approach; however, they were rigid and uncomfortable for sleep.

Preston and Sanchez will work to transform the design of the cap into a soft, lightweight, textile-based version to make sleep easier, while also allowing the caps to be customizable and tailored for each patient.

“One of the areas of expertise we have here at Rice is designing wearable devices from soft and flexible materials,” Preston, an assistant professor of mechanical engineering, said in a news release. “We’ve already shown this concept works in rigid device prototypes. Now we’re building a soft, breathable cap that people can comfortably wear while they sleep.”

Additionally, the research team is pursuing ways to adapt their technology to measure neuroinflammation and stimulate the brain’s natural plasticity. Neuroinflammation, or swelling in the brain, can be caused by injury, stroke, disease or lifestyle factors and is increasingly recognized as a driver of neurodegeneration, according to Rice.

“Our brain has an incredible ability to rewire itself,” Aazhang added in the release. “If we can harness that through technology, we can open new doors for treating not just dementia but also traumatic brain injury, stroke, Parkinson’s disease and more.”

The project represents Rice’s broader commitment to brain health research and its support for the Dementia Prevention Research Institute of Texas (DPRIT), which passed voter approval last week. The university also recently launched its Rice Brain Institute.

As part of the project, Houston Methodist will provide access to clinicians and patients for early trials, which include studies on patients who have suffered traumatic brain injury and stroke.

“We have entered an era in neuroscience that will result in transformational cures in diseases of the brain and spinal cord,” Britz said in the release. “DPRIT could make Texas the hub of these discoveries.”

Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.