Thai Lee, of Austin, remains at the top of the list in Texas. Photo courtesy of SHI

Of the country's 100 most successful female entrepreneurs, 12 call Texas home, according to Forbes and its 2023 list of America's Richest Self-Made Women, released June 1.

"Bolstered in part by a rebound in the stock market, [the richest 100 female entrepreneurs] are cumulatively worth a record $124 billion, up nearly 12 percent from a year ago," says Forbes.

To make the Forbes list, women had to garner wealth on their own, rather than by inheriting or winning it. Texas' wealthiest women have made their fortunes in fields ranging from home health care, insurance, and aviation logistics to jewelry design, dating apps, and running the show at SpaceX. Austin is home to the largest concentration of these self-made Texans with eight Austinites making the list.

With an estimated net worth at $4.8 billion, Thai Lee, of Austin, remains at the top of the list in Texas, and ranks No. 5 nationally.

She falls behind only No. 1 Diane Hendricks of Wisconsin (co-founder of ABC Supply, $15 billion net worth); No. 2 Judy Love of Oklahoma (chairman and CEO, Love's Travel Stops And Country Stores, $10.2 billion); No. 3 Judy Faulkner of Wisconsin (founder and CEO, Epic Systems, $7.4 billion); and No. 4 Lynda Resnick of California (co-founder and co-owner of Wonderful Company, $5.3 billion) among America's richest self-made women.

For some additional perspective, Oprah Winfrey lands at No. 13 on the list for 2023. The TV titan (and most famous woman on the planet) has an estimated net worth of $2.5 billion, Forbes says.

Austin's Lee, a native of Bangkok who holds an MBA from Harvard University, is founder, president, and CEO of SHI International Corp., a provider of IT products and services with a projected revenue of $14 billion in 2023. Fun fact: "Lee majored in both biology and economics," Forbes says, "in part because her English was less than perfect and she wanted to avoid writing and speaking in class."

The other seven Austin women on the list are:

  • Lisa Su, No. 34, Austin. Forbes pegs Su’s net worth at $740 million, tying her with April Anthony of Dallas. The native of Taiwan is president and CEO of Santa Clara, California-based semiconductor company Advanced Micro Devices.
  • Kendra Scott, No. 47, of Austin.Forbes says she has amassed a net worth of $550 million as founder of Kendra Scott LLC, which designs and sells jewelry in more than 100 stores (and is worth $360 million). The celebrity entrepreneur is also a judge on TV's Shark Tank.
  • Whitney Wolfe Herd, No. 52, of Austin. She is worth an estimated $510 million. Herd is co-founder and CEO of Bumble Inc., which operates two online dating apps: Bumble and Badoo. She owns a 17% stake in Bumble and became the youngest self-made woman billionaire after it went public in February 2021.
  • Paige Mycoskie, No. 73, of Austin. She is worth an estimated $380 million. Mycoskie created founded her 1970s-inspired California lifestyle brand, Aviator Nation, which took off during the pandemic and now has 16 retail locations across the U.S. If the name sounds familiar, that's because she's the sister of TOMS founder Blake Mycoskie, with whom she competed on TV's The Amazing Race.
  • Imam Abuzeid, No. 77, of Austin. Her net worth is estimated at $350 million. Abuzeid is the co-founder and CEO of Incredible Health, which she started in 2017 to help alleviate America's nursing shortage. Forbes describes it as "a souped-up version of LinkedIn for nurses." Abuzeid is one of only a handful of Black female founders to run a company valued at more than $1 billion, Forbes notes.
  • Julia Cheek, No. 92, of Austin. Her net worth is estimated at $260 million. Cheek founded at-home testing company Everly Health in 2015 "out of frustration at having to pay thousands for lab testing to diagnose issues related to vitamin imbalance," Forbes says. It got a Shark Tank deal with Lori Greiner and is now worth roughly $1.8 billion.
  • Belinda Johnson, No. 96, of Austin. She is worth an estimated $250 million. Johnson was Airbnb's first chief operating officer and led many of its legal disputes. She stepped down from that role in March 2020, Forbes says, and left the company's board in June 2023.

The remaining Texas women on the list include:

  • Gwynne Shotwell, No. 27, of Jonesboro (Coryell-Hamilton counties). Her net worth is estimated at $860 million. Shotwell is president and COO of Elon Musk's SpaceX. She manages the operations of the commercial space exploration company and owns an estimated stake of 1 percent, Forbes says.
  • Robyn Jones, No. 29, of Fort Worth. Her net worth is estimated at $830 million. Jones is founder of Westlake-based Goosehead Insurance Agency LLC. She started the property and casualty insurance agency in 2003 after being frustrated with her truck-driver husband's "road warrior lifestyle," Forbes says. He joined her in 2004 and they took the company public in 2018. It has nearly 1,000 franchised offices.
  • April Anthony, No. 34, of Dallas. Forbes puts her net worth at $740 million. She founded the Dallas-based home health and hospice division of Encompass Health Corp and sold it for $750 million to HealthSouth. In 2022, she was named CEO of VitalCaring, a home health and hospice care firm.
  • Kathleen Hildreth, No. 44, of Aubrey. Her net worth is estimated at $590 million. Hildreth is co-founder of M1 Support Services LP, an aviation logistics company based in Denton. A service-disabled Army veteran, she graduated from West Point in 1983 and was deployed all around the world as a helicopter pilot.
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This article originally ran on CultureMap.

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”