3 Houston innovators to know this week

Who's who

This week's roundup of Houston innovators includes Anouk van Pol of INGU Solutions, Eric Tait of Urban Capital Network, and Chris Howard of Softeq. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from venture capital to energy — recently making headlines in Houston innovation.

Anouk van Pol, co-founder and COO of INGU Solutions

INGU Solutions has established its U.S. office in Houston — and is ready to tap into the city's energy industry with its revolutionary pipeline inspection-as-a-service model. Photo via LinkedIn

After generating some fresh funds from U.S. investors in 2019, Canadian pipeline services company INGU Solutions decided it was time to open a new office somewhere in the country. The startup led by a father-daughter team chose Houston and opened up an office just ahead of the first wave of the COVID-19 pandemic.

“The idea was to be closer to our customers,” Anouk van Pol, COO, tells InnovationMap. “Houston is the oil and gas hub, and just being able to be in [our clients'] offices and be there in person it just helps. I hope at one point COVID passes and that we can make use out of it a bit more.

Despite the challenges of the pandemic, INGU, which uses data analytics and a small sensor to inspect pipes within the energy and water industries, grew 60 percent over the past two years. Click here to read more.

Eric Tait, co-founder at Urban Capital Network

Urban Capital Network have launched a fund-of-funds to allow investors to tap into later-stage startups at a much lower barrier of entry. Photo via urbancapitalnetwork.com

With its new fund of funds, Houston-based Urban Capital Network is allowing its members the chance to invest in venture funds at a much lower barrier of entry. The Horizon Fund II will deploy capital in up to five funds — each with 15 to 30 portfolio companies.

Eric Tait, co-founder at UCN, says they are looking for variety in the funds they invest in and are targeting top-tier, and highly rated VC firms all over the country that UCN's leadership has connections with.

“We’re relatively agnostic in terms of industry,” Tait says. “We do try to have a portfolio allocation that will create a return threshold that is varied.” Click here to read more.

Chris Howard, CEO and founder of Softeq

A Houston software company has announced its new venture fund. Photo courtesy of Softeq

Last week, Houston-based Softeq Development Corporation, a global full-stack development company, launched The Softeq Venture Fund, a $40 million venture fund to invest in seed and series A startup rounds. According to a news release, more than half the fund will be deployed to power the Softeq Venture Studio, Softeq's recently launched accelerator program.

“For generations, the state of Texas has been home to world-renowned tech companies who have greatly contributed to our regional success. As a local entrepreneur, advisor, and angel investor, it’s been my dream for many years to create a venture fund benefiting startups," says Christopher A. Howard, founder and CEO of Softeq, in the release. "I am proud to increase our support of the state’s early-stage tech community. Our investment fund is designed to attract tech visionaries from both inside and outside the state and grow innovative concepts in Houston." Click here to read more.

INGU Solutions has established its U.S. office in Houston — and is ready to tap into the city's energy industry with its revolutionary pipeline inspection-as-a-service model. Photo via ingu.com

Innovative Canadian company taps into Houston market to better serve energy customers

in the pipeline

On average, oil and gas pipelines are inspected every five years, which, considering pipelines in the United States are more than 60 years old, just isn't cutting it. Operators face costly and damaging leaks on cracks and incidences that are totally avoidable with more regular inspection. The issue is inspection isn't an easy process — unless INGU Solutions is involved.

The Alberta, Canada-based company has created a hardware component — called a Piper — that's about the size of a baseball. The device can be run through pipes of any size to inspect and detect internal issues. INGU has an inspection-as-a-service model so that whatever data is collected by the Pipers is analyzed and provided to clients without any more steps from them.

The idea for the device came to John van Pol, founder and CEO, who has a background in nuclear physics and founded the company in 2015. Now, he runs the company with his daughter, Anouk van Pol, who started as an analyst and working in the field for INGU and now serves the company as co-founder and COO.

The Piper is smaller than a baseball and can flow through any sized pipe used in the oil and gas industry. Photo via ingu.com

In 2017, INGU was selected to be a part of Chevron's inaugural Catalyst Program cohort and Chevron Technology Ventures — along with two other U.S. investors — contributed to the company's series A round in 2019. This led to INGU establishing its U.S. operations in Houston in order to grow their American team and to be closer to customers. Then, the pandemic hit.

“The idea was to be closer to our customers,” Anouk tells InnovationMap. “Houston is the oil and gas hub, and just being able to be in [our clients'] offices and be there in person it just helps. I hope at one point COVID passes and that we can make use out of it a bit more.

"The other thing is you open up your market on the hiring side," she says, adding that the company has two U.S. employees now.

INGU first had an office in The Cannon, but now operates locally at The Ion in the Common Desk coworking space with an office suite to support its local team. In 2019, the company was named to Plug and Play's inaugural Houston cohort and as a most-promising business by Rice Alliance at OTC.

Anouk, who was selected for Forbes 30 Under 30 in energy in 2020, and her father both split their time between Houston and Alberta, usually alternating so that the van Pols have a presence in each office at all times, but both are currently in town for the 34th annual Pipeline Pigging and Integrity Management conference, or PPIM. It's the OTC for the pipeline industry, Anouk says.

Ahead of the conference and despite the challenges the pandemic has posed for INGU, Anouk says the company has seen significant growth over the past two years.

"We grew 60 percent last year," she says. "which is pretty good for what's been happening over the past two years."

From a hardware perspective, the pandemic's impact has been relatively small. The Pipers are designed with off-the-shelf materials, which INGU stocked up on — avoiding any supply chain shortages. Additionally, INGU can send the devices to pipeline operators, who can deploy them while the devices send the collected data directly to INGU.

Anouk van Pol is the company's COO. Photo via LinkedIn

The company, which anticipates a secondary series A round this year in addition to tripling its annual revenue, has an environmental, social, and governance, or ESG, component to its business. While half of INGU's clients are in the energy industry and Pipers contribute to reducing waste within oilfield operations, the other half of customers are within the water industry. Water infrastructure is 100 years old, and Anouk says about 6 billion gallons of water are wasted each day.

"That's 40 percent of all water, and because so much water is lost, you need more power and energy," Anouk says. "Where we see oil and gas is aimed at prevention in well condition, etc., the water market is doing a lot of leak protection."

In both industries, Pipers are preventing waste and allowing companies to make positive moves in their ESG plans.

INGU has clients all over the world and servicing these various types of pipes and businesses is growing INGU's database, which better benefits their inspection-as-a-service capabilities.

"The more we grow, the more we can and will learn, and then go in this self-fulfilling cycle," Anouk says.

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

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