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Houston biotech startup announces merger and $10M series A

A biotech startup focused on developing therapeutics for neurodegenerative and autoimmune diseases has some big news to share. Photo via Getty Images

A Houston company has emerged from stealth mode to announce a merger and a round of financing.

Coya Therapeutics, a clinical-stage biotech startup that focuses on creating therapeutics for neurodegenerative and autoimmune diseases, announced that it has completed a merger with Nicoya Health Inc. and raised $10 million in its series A. The round was led by Florida-based Allele Capital Partners LLC. Howard Berman, founder and board of directors for imaware, has been named CEO of Coya, as well as a member of the company's board of directors.

Coya's therapeutics uses innovative work from Dr. Stanley H. Appel, co-director of Houston Methodist Neurological Institute and Chair of the Stanley H. Appel Department of Neurology at Houston Methodist Hospital. The researcher has created a way to "isolate dysfunctional Tregs from a patient, convert them to a highly functional and neuroprotective condition, and expand these cells into the billions for intravenous reinfusion back to the patient," says Berman in a news release. This revolutionary work overcomes previous limitations in the field.

"I'm excited to have the opportunity to lead Coya at such an exciting and pivotal phase of growth," Berman says. "Through our sponsored research program in conjunction with Dr. Appel, we look forward to continuing advancement of this promising work and translating this work into a meaningful therapy for patients."

The company's fresh funds will be used to continue work on the company's lead therapeutic program, ALS001, an autologous, expanded Treg cell therapy for amyotrophic lateral sclerosis (ALS) patients , as well as to introduce clinical pipeline candidates targeting Parkinson's disease, Alzheimer's disease, frontal temporal dementia, and more, according to the release.

"Patients with neurodegenerative diseases are in desperate need of transformative therapeutic options; harnessing the neuro-protective effects of Treg cell therapy shows great potential in unlocking a new treatment paradigm and may enable us to revolutionize care for patients with devastating neurodegenerative diseases," says Appel. "We have successfully demonstrated, in a phase 1 trial, the safety and tolerability of autologous infusions of expanded Tregs in ALS patients, with the potential of slowing or halting disease progression. Ongoing studies provide a transformative framework for advanced clinical trials in ALS and other neurodegenerative disorders."

Tribal Capital Markets LLC acted as sole placement agent for the offering, according to the release, and Allele Capital Partners — through Tribal Capital Markets — was responsible for sourcing, investing and executing the $10 million offering.

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Building Houston

 
 

This autonomous freight delivery provider has entered the Texas market. Photo via VAS

A global car brand has expanded its autonomous transport-as-a-service company to Texas.

Volvo Autonomous Solutions, or VAS, announced it has established an office in Fort Worth to set up its first self-driving freight corridors between Dallas-Fort Worth and El Paso, as well as from Dallas to Houston. Ahead of commercial launch, VAS has started hauling freight for key customers like DHL and Uber Freight for testing purposes.

"At Volvo Autonomous Solutions, we believe the path to autonomy at scale is through reducing the friction and complications around ownership and operations for customers," says Nils Jaeger, president of VAS, in a news release. "This is why we have taken the decision to be the single interface to our customers and take full ownership of the elements required for commercial autonomous transport. With the opening of our office in Texas and start of operational activities, we are building the foundations for a transport solution that will change the way we move goods on highways."

As a part of the Volvo Group, VAS provides its Autonomous Transport Solutions — a combination of hardware, software, and services — to its customers.

"Through our Autonomous Transport Solution, our ambition is to create a new source of industry capacity that will ease some of the burden of the increasing demand for freight while also enabling local drivers to shift into short-haul jobs that will keep them closer to home. This will unlock significant efficiencies in the entire supply chain and benefit everyone in the transportation industry," says Sasko Cuklev, head of On-Road Solutions, in the release.

The company has a partnership with Aurora, which includes the integration of the Aurora Driver with Volvo's on-highway truck offering.

Autonomous freight tech development in Texas has ramped up, with Ikea testing deliveries last fall and Silicon Valley-based Kodiak Robotics entering the Texas market in 2019.

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