Houston Voices

The Valley of Death: How universities can help startups survive

Universities and startups have different goals, but that doesn't mean that educational institutions can't help new companies through the valley of death that is entering the marketplace. Miguel Tovar/University of Houston

When looking out over the commercialization landscape, the vast space a product has to travel from discovery to the marketplace appears to be growing. For many startup companies, this so-called "valley of death" means the end of the road. Without support, resources and, most importantly, cash, many startups will shut down.

Universities are becoming epicenters for startup activity. In many ways, they are perfectly positioned to support commercialization, with a pro-research environment, lab facilities, faculty expertise, human resources, and tech transfer operations.

But there's one problem.

"Universities and industry are like two icebergs moving in different directions," says Montgomery Alger, professor of chemical engineering and director of the Institute for Natural Gas Research at Pennsylvania State University. "Companies need to make quarterly profits quickly through new products and services, and the academic business model is not set up to support that need."

The question then becomes: how can universities shift their approach to bridge the gap from idea to market?

Spark innovation on campus

Universities may need to rethink a few things when it comes to their innovation ecosystems.

"Universities must play a key role in the commercialization process because so many ideas start there," says Walter Ulrich, longtime technology management consultant and former chief executive officer of the Houston Technology Center, previously one of Houston's most prominent accelerators and incubators. "Investors and inventors go to where there's a critical mass of opportunity, so universities need to step up their game."

Supporting commercialization gives universities a chance to be even more relevant when it comes to local economic development. Changing the institutional culture, however, may be necessary if universities want to become a true bridge across the valley of death.

Alger, who spent part of his early career working for GE Global Research before transitioning to academia, argues that this can be done by creating multidisciplinary teams of researchers across the university to help industry bring ideas to the market — a foundational part of the bridge.

Another way to spark innovation is to boost technology transfer or industry alliance offices, according to Susan Jenkins, managing director of the Innovative Genomics Institute at the University of California, Berkeley. Hiring an intellectual property manager to work specifically with academic research institutes can go a long way in supporting an innovation environment.

"When it comes to innovation, universities need to be open to new ideas," says Jenkins. "They need to be able to shift quickly to the next best thing, whatever is hot at the moment. That's how the market works."

Disrupt the academic business model

Universities are designed to support educational throughput. Most are not set up to support commercialization activities.

"Universities are stuck in a rut," says Alger. "There has to be a conscious decision to make the university function like a business to support business."

That means putting the right resources in place to fix the many pain points companies may experience. Long response times, extensive paperwork processes and the lack of system wide policies governing university-corporate relationships can often lead startups and industry partners to look elsewhere for solutions.

"Just like scientists need to be innovative, the administration needs to be innovative," says Jenkins. "If you want to be in the race, you have to be ready to be flexible and adapt."

Another way to disrupt the academic business model is to consider commercialization as part of the promotion and tenure process.

"If universities are serious about advancing technology entrepreneurship, they must recognize faculty who drive commercialization," says Ulrich.

Alger agrees. "There has to be some kind of incentive structure established for the research program when it comes to technology transfer."

Six ways to get serious about startups

According to Ulrich, who has launched hundreds of successful startups throughout his career, startups need cash — and lots of it. Early licensing fees, short-term payouts, competitive prices for rent, and other services charged by the universities could end up keeping startups from success.

Ulrich says "Cash is king," noting that an increased demand for early-stage capital has widened the valley of death.

There are a few things universities can do to support early-stage startups:

1. Invest in long-term payouts.
Most venture firms expect returns in 7 to 10 years. By establishing longer-term payouts, more cash will stay in the hands of the entrepreneur.

2. Consider equity for returns.
Universities can negotiate equity, possibly even in the leasing of space.

3. License more broadly.
Diversifying provides more pathways for inventors to find the right fit for licensing their product.

4. Provide resources as investment.
Explore resources such as coursework credits for startups looking to expand their knowledge base.

5. Establish seed funding.
Entrepreneurs can use even the smallest amounts of cash. Not having to give it back is even better.

6. Create a university-focused angel network.
With broad alumni and donor bases, universities can more readily tap into its business community to build a network of investors.

Incorporating different streams of funding could be very important, says Jenkins, who worked with a foundation to establish entrepreneurial fellowship program at UC-Berkeley.

It's a dimension, however, that some campuses may not be set up to deal with yet.

"Product development within the academic research environment will take a focused investment," says Alger. "Universities just need to give the right attention and priority to it."

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This article originally appeared on the University of Houston's The Big Idea.

Lindsay Lewis is the director of strategic research communications at UH.

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Building Houston

 
 

Houston is home to many talented researchers — and about 60 have been recognized by a global study for being among the most cited individuals in their fields. Photo via Getty Images

Nearly 60 scientists and professors from Houston-area universities and institutions, working in fields from ecology to immunology, have been named among the most-cited researchers in the world.

The Clarivate Highly Cited Researchers 2022 list considers a global pool of public academic papers that rank in the top 1 percent of citations for field and publication year in the Web of Science. It then ranks researchers by the number of times their work has been cited, or referenced, by other researchers, which, according to the University of Houston, helps their findings "become more impactful and gain further credibility."

This year 6,938 researchers from 70 different countries were named to this list. About 38 percent of the researchers are based in the U.S.

“Research fuels the race for knowledge and it is important that nations and institutions celebrate the individuals who drive the wheel of innovation. The Highly Cited Researchers list identifies and celebrates exceptional individual researchers who are having a significant impact on the research community as evidenced by the rate at which their work is being cited by their peers," says David Pendlebury, head of research analysis at the Institute for Scientific Information at Clarivate, in a statement. "These individuals are helping to transform human ingenuity into our world’s greatest breakthroughs.”

Harvard University was home to the most researchers, with 233 researchers making the list, far outpacing Stanford University, which had the second highest total of 126 researchers.

Texas universities and institutions had a strong showing, too. The University of Texas at Austin had 31 researchers on the list, tying UT with the University of Minnesota and Peking University in China for the No. 35 spot. MD Anderson had 30 researchers on the list, the most among organizations in Houston, earning it a 38th place ranking, tied with the University of Maryland and University of Michigan.

Below is a list of the Houston-area highly cited researchers and their fields.

From UT MD Anderson Cancer Center

  • Jaffer Ajani (Cross-Field)
  • James P. Allison (Immunology)
  • Jan A. Burger (Clinical Medicine)
  • George Calin (Cross-Field)
  • Jorge Cortes (Clinical Medicine)
  • Courtney DiNardo (Clinical Medicine)
  • John V. Heymach (Clinical Medicine)
  • David Hong (Cross-Field)
  • Gabriel N. Hortobagyi (Cross-Field)
  • Robert R. Jenq (Cross-Field)
  • Hagop M.Kantarjian (Clinical Medicine)
  • Marina Y. Konopleva (Clinical Medicine)
  • Dimitrios P. Kontoyiannis (Cross-Field)
  • Scott E. Kopetz (Clinical Medicine)
  • Alexander J. Lazar (Cross-Field)
  • J. Jack Lee (Cross-Field)
  • Anirban Maitra (Clinical Medicine)
  • Robert Z. Orlowski (Clinical Medicine)
  • Padmanee Sharma (Clinical Medicine and Molecular Biology and Genetics)
  • Anil K. Good (Cross-Field)
  • Jennifer A. Wargo (Molecular Biology and Genetics)
  • William G. Wierda (Clinical Medicine)

From Baylor College of Medicine

  • Erez Lieberman Aiden (Cross-Field)
  • Nadim J. Ajami (Cross-Field)
  • Christie M. Ballantyne (Clinical Medicine)
  • Malcolm K. Brenner (Cross-Field)
  • Hashem B. El-Serag (Clinical Medicine)
  • Richard Gibbs (Cross-Field)
  • Heslop, Helen Cross-Field
  • Joseph Jankovic (Cross-Field)
  • Sheldon L. Kaplan (Immunology)
  • Joseph F. Petrosino (Cross-Field)
  • Cliona Rooney (Cross-Field)
  • James Versalovic (Cross-Field)
  • Bing Zhang (Cross-Field)

From Rice University

  • Plucker M. Ajayan (Materials Science)
  • Pedro J. J. Alvarez (Environment and Ecology)
  • Naomi Halas (Materials Science)
  • Jun Lou (Materials Science)
  • Antonios G. Nikos (Cross-Field)
  • Aditya D. Mohite (Cross-Field)
  • Peter Nordlander (Materials Science)
  • Ramamoorthy Ramesh (Physics)
  • James M. Tour (Materials Science)
  • Robert Vajtai (Materials Science)
  • Haotian Wang (Chemistry)
  • Zhen-Yu Wu (Cross-Field)
  • From University of Houston
  • Jiming Bao (Cross-Field)
  • Shuo Chen (Cross-Field)
  • Whiffing Ren (Cross-Field)
  • Zhu Han (Computer Science)

From UTMB Galveston

  • Vineet D.Menachery (Microbiology)
  • Nikos Vasilakis (Cross-Field
  • Scott C. Weaver (Cross-Field)
  • From UT Health Science Center-Houston
  • Eric Boerwinkle (Cross-Field)

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