who's who

3 Houston innovators to know this week

This week's Houston innovators to know include Travis Parigi of LiquidFrameworks, Kathy Luders of NASA, and Stephen Spann of the University of Houston. Photos courtesy

Starting a new week, we'd like to introduce you to three Houston innovators who have recently made headlines. All three represent industries at the core of Houston's business community — from space and energy to health care.

Travis Parigi, founder and CEO of LiquidFrameworks

Travis Parigi, founder and CEO of LiquidFrameworks, joins the Houston Innovators Podcast to discuss how he's navigating both a global pandemic and an oil downturn. Photo courtesy of LiquidFrameworks

Travis Parigi, founder and CEO of LiquidFrameworks, joined the Houston Innovators Podcast to discuss how both the oil downturn and the pandemic has affected his business, which provides cloud-based, mobile field operations management solutions to oil and gas, environmental, and industrial service companies.

"We've seen these types of challenges in the past within the oil and gas space — it is cyclical based on commodities," Parigi explains on thi week's episode of the Houston Innovators Podcast. "We're well positioned to weather these storms."

Parigi shares his biggest concerns about the oil and gas market and how he's looking into partnering with another Houston energy tech startup, Data Gumbo, on the episode. Listen and read more.

Kathy Lueders, associate administrator of the Human Exploration and Operations Mission Directorate at NASA's Johnson Space Center

Kathy Lueders will lead the future of human space flight at NASA. Photo via nasa.gov

NASA's Johnson Space Center, home to human exploration, has a new leader. Kathy Lueders, formerly the commercial crew program manager, has been named associate administrator of the Human Exploration and Operations (HEO) Mission Directorate by NASA Administrator Jim Bridenstine on Friday, June 12.

"Kathy gives us the extraordinary experience and passion we need to continue to move forward with Artemis and our goal of landing the first woman and the next man on the Moon by 2024," says Bridenstine in a news release. "She has a deep interest in developing commercial markets in space, dating back to her initial work on the space shuttle program."

Lueders has been with NASA for over 12 years — spending time at both JSC and Kennedy Space Center in Florida. Read more.

Dr. Stephen Spann, founding dean of the University of Houston's College of Medicine

The University of Houston broke ground on its new medical school building and named the College of Medicine's inaugural class. Photo via UH.edu

The University of Houston is the first institution in town in about 50 years to establish a new medical school, and UH is doing it for a specific reason — to get more primary care doctors in practice. UH's College of Medicine plans to have 50 percent of graduates choose primary care specialties including family medicine, general internal medicine, and general pediatrics. For some perspective, nationally, only about 20 percent of medical students choose primary care.

"We were very deliberate in our pursuit of medical students who fit the mission. This is much different than most other medical schools because we need different solutions for the current health care problems facing our city and state," said Dr. Stephen Spann, founding dean of the College of Medicine, in a statement. Read more.

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Building Houston

 
 

San Diego-based rBIO moved to Houston to take advantage of the growing ecosystem of biomanufacturing and synthetic biology. Photo via Getty Images

Cameron Owen had an idea for a synthetic biology application, and he pitched it to a handful of postdoctoral programs. When he received the feedback that he didn't have enough research experience, he decided to launch a startup based in San Diego around his idea. He figured that he'd either get the experience he needed to re-apply, or he'd create a viable company.

After three years of research and development, Owen's path seems to have taken him down the latter of those two options, and he moved his viable company, rBIO, to Houston — a twist he didn't see coming.

“Houston was not on my radar until about a year and a half ago,” Owen says, explaining that he thought of Houston as a leading health care hub, but the coasts still had an edge when it came to what he was doing. “San Diego and the Boston area are the two big biotech and life science hubs.”

But when he visited the Bayou City in December of 2021, he says he saw first hand that something new was happening.

“Companies from California like us and the coastal areas were converging here in Houston and creating this new type of bioeconomy,” he tells InnovationMap.

Owen moved to Houston last year, but rBIO still has an academic partner in Washington University in St. Louis and a clinical research organization it's working with too, so he admits rBIO's local footprint is relatively small — but not for long.

"When we look to want to get into manufacturing, we definitely want to build something here in Houston," he says. "We’re just not to that point as a company."

In terms of the stage rBIO is in now, Owen says the company is coming out of R&D and into clinical studies. He says rBIO has plans to fundraise and is meeting with potential partners that will help his company scale and build out a facility.

With the help of its CRO partner, rBIO has two ongoing clinical projects — with a third coming next month. Owen says right now rBIO is targeting the pharmaceutical industry’s biologics sector — these are drugs our bodies make naturally, like insulin. About 12 percent of the population in the United States has diabetes, which translates to almost 40 million people. The demand for insulin is high, and rBIO has a way to create it — and at 30 percent less cost.

This is just the tip of the iceberg — the world of synthetic biology application is endless.

“Now that we can design and manipulate biology in ways we’ve never been able to before,” Owen says, "we’re really only limited by our own imagination.”

Synthetic biology is a field of science that involves programing biology to create and redesign natural elements. While it sounds like science fiction, Owen compares it to any other type of technology.

“Biology really is a type of software,” he says. “Phones and computers at their core run on 1s and 0s. In biology, it’s kind of the same thing, but instead of two letters, it’s four — A, C, T, and G.”

“The cool thing about biology is the software builds the hardware,” he continues. “You put that code in there and the biology builds in and of itself.”

Owen says the industry of synthetic biology has been rising in popularity for years, but the technology has only recently caught up.

“We’re exploring a brave new world — there’s no doubt about that,” Owen says.

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