cardiatric care

Houston heart health startup secures $8M in funding, announces new partnerships

CardioOne has fresh funding and new partners, resulting in a five-state expansion. Photo via Getty Images

With fresh funding, a Houston-based health tech platform that's less than a year old has grown its United States footprint.

CardioOne, which has created a cardiology care delivery enablement platform that serves independent cardiologists, has closed an $8 million seed round of funding and secured three new partnerships. Axios and Crunchbase report that the round has closed, and CardioOne confirms the funding and new partnerships in a press release.

The company has three new partnerships with independent cardiology clinics in New Jersey, Florida, and Pennsylvania, Cardiac Associates of New Jersey, Twin Hearts LLC, and Corrieius Cardiology. The trio joins existing partner practices in Texas and Maryland.

In addition to joining forces with these practices, CardioOne has entered into a partnership with MedAxiom, which is described as being "the cardiovascular community’s premier source for organizational performance solutions," in the release.

“CardioOne is optimizing cardiology practice management and providing new options for independent cardiologists,” Joe Sasson, MedAxiom’s executive vice president of ventures and chief commercial officer, says in the news release. “With CardioOne, independent cardiology practices can access the scale and leverage typically reserved for large hospital groups and are empowered to grow through additional service lines, strong network relationships, and payor contracts, including value-based care arrangements.”

Dr. Jasen Gunderson, who's based in Denver, is the CEO and co-founder of CardioOne, which was founded last year. He explains the challenges of independent cardiologists, which includes inefficient revenue cycle tools, incomplete vendor management systems, and other tech-based and administrative obstacles — most of which CardioOne addresses.

“Inadequate and fragmented technology is at the root of many of the problems that independent cardiologists are facing today,” Gunderson says in the release. “CardioOne’s solution removes the heavy administrative burdens, empowering cardiologists to focus on their expertise and true passion – the practice of medicine without feeling forced into acquisition.”

CardioOne's mission is to continue to help cardiology practices maintain their independence while keeping up with demand, patient care, and business growth.

"Our independence and clinical autonomy has allowed our practice to provide more personalized care to our patients, but in a consolidating market... the resources and technology investments required to run a practice group today make staying independent more difficult than ever before,” Dr. John H. Lee of Cardiac Associates of North Jersey, says in the release. “CardioOne is a true collaborator, serving as an extension of our operations and allowing us to focus on doing what we love — caring for patients.”

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A research team housed out of the newly launched Rice Biotech Launch Pad received funding to scale tech that could slash cancer deaths in half. Photo via Rice University

A research funding agency has deployed capital into a team at Rice University that's working to develop a technology that could cut cancer-related deaths in half.

Rice researchers received $45 million from the National Institutes of Health's Advanced Research Projects Agency for Health, or ARPA-H, to scale up development of a sense-and-respond implant technology. Rice bioengineer Omid Veiseh leads the team developing the technology as principal investigator.

“Instead of tethering patients to hospital beds, IV bags and external monitors, we’ll use a minimally invasive procedure to implant a small device that continuously monitors their cancer and adjusts their immunotherapy dose in real time,” he says in a news release. “This kind of ‘closed-loop therapy’ has been used for managing diabetes, where you have a glucose monitor that continuously talks to an insulin pump. But for cancer immunotherapy, it’s revolutionary.”

Joining Veiseh on the 19-person research project named THOR, which stands for “targeted hybrid oncotherapeutic regulation,” is Amir Jazaeri, co-PI and professor of gynecologic oncology at the University of Texas MD Anderson Cancer Center. The device they are developing is called HAMMR, or hybrid advanced molecular manufacturing regulator.

“Cancer cells are continually evolving and adapting to therapy. However, currently available diagnostic tools, including radiologic tests, blood assays and biopsies, provide very infrequent and limited snapshots of this dynamic process," Jazaeri adds. "As a result, today’s therapies treat cancer as if it were a static disease. We believe THOR could transform the status quo by providing real-time data from the tumor environment that can in turn guide more effective and tumor-informed novel therapies.”

With a national team of engineers, physicians, and experts across synthetic biology, materials science, immunology, oncology, and more, the team will receive its funding through the Rice Biotech Launch Pad, a newly launched initiative led by Veiseh that exists to help life-saving medical innovation scale quickly.

"Rice is proud to be the recipient of the second major funding award from the ARPA-H, a new funding agency established last year to support research that catalyzes health breakthroughs," Rice President Reginald DesRoches says. "The research Rice bioengineer Omid Veiseh is doing in leading this team is truly groundbreaking and could potentially save hundreds of thousands of lives each year. This is the type of research that makes a significant impact on the world.”

The initial focus of the technology will be on ovarian cancer, and this funding agreement includes a first-phase clinical trial of HAMMR for the treatment of recurrent ovarian cancer that's expected to take place in the fourth year of THOR’s multi-year project.

“The technology is broadly applicable for peritoneal cancers that affect the pancreas, liver, lungs and other organs,” Veiseh says. “The first clinical trial will focus on refractory recurrent ovarian cancer, and the benefit of that is that we have an ongoing trial for ovarian cancer with our encapsulated cytokine ‘drug factory’ technology. We'll be able to build on that experience. We have already demonstrated a unique model to go from concept to clinical trial within five years, and HAMMR is the next iteration of that approach.”

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