3 clean energy innovators make Forbes list of top young energy professionals

under 30

Three young professionals have made the cut for this year's Forbes Under 30 list in the Energy and Green Tech list for 2025. Photos via Forbes

A handful of Houstonians have been named to the Forbes 30 Under 30 Energy and Green Tech list for 2025.

Kip Daujotas is an investment associate at Aramco Ventures, a $7.5 billion venture capital arm of the world's largest energy company. Houston is the Americas headquarters for Saudi Aramco. Since its inception in 2012, Aramco Ventures has invested in more than 100 tech startups. Daujotas joined the team over two years ago after studying for an MBA at Yale University. He led Aramco’s first direct air capture (DAC) investment — in Los Alamos, New Mexico-based Spiritus.

Also representing the corporate side of the industry, Wenting Gao immigrated from Beijing to obtain an economics degree from Harvard University, then got a job at consulting giant McKinsey, where she recently became the firm’s youngest partner. Gao works on bringing sustainability strategies to energy and materials companies as well as investors. Her areas of expertise include battery materials, waste, biofuels, and low-carbon products.

Last but not least, Houston entrepreneur Rawand Rasheed is co-founder and CEO of Houston-based Helix Earth. He co-founded the startup after earning a doctoral degree from Rice University and co-inventing Helix’s core technology while at NASA, first as a graduate research fellow and then as an engineer. The core technology, a space capsule air filtration system, has been applied to retrofitting HVAC systems for commercial buildings.

Each year, Forbes 30 Under 30 recognizes 600 honorees in 20 categories. The 2025 honorees were selected from more than 10,000 nominees by Forbes staff and a panel of independent judges based on factors such as funding, revenue, social impact, scale, inventiveness, and potential.

Specifically, the Energy & Green Tech category recognizes young entrepreneurs driving innovation that’s aimed at creating a cleaner, greener future.

“Gen Z is one of the fastest-growing groups of entrepreneurs and creators, who are reshaping the way the world conducts business, and our Under 30 class of 2025 proves that you can never begin your career journey too early,” says Alexandra York, editor of Forbes Under 30. “With the expansion across AI, technology, social media, and other industries, the honorees on this year’s list are pushing the boundaries and building their brands beyond traditional scopes.”

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This article originally ran on EnergyCapital.

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Houston adds yet another feather to its cap and has been recognized as the best place to be after graduating college. Photo via Getty Images

Houston ranks as top spot for young professionals based on standard of living

moving to Houston

Recruiting talent in the Houston area? Might want to share this tidbit of information.

A new study by two California researchers names Houston as the No. 1 place among the country’s 50 largest spots for college graduates to enjoy the highest standard of living. Why? Because, the study says, “local income is relatively high, cost of living is moderate, and there are no state taxes.”

Among places of all sizes, the study ranks Houston second in terms of the standard of living for college graduates. McAllen nabs the No. 1 spot, followed by Houston; Huntington, West Virginia; Beaumont; and Charleston, South Carolina.

In December, job website Indeed named Houston one of the 10 best cities in 2022 for recent college graduates. The 10 cities offer “many outstanding entry-level positions in a range of industries,” Indeed says.

More good news for Houston: The study ranks puts it at No. 2 (behind Buffalo, New York) among the 50 largest places in the U.S. for providing the highest standard of living for high school graduates.

According to the study, the five places with the highest standard of living for those with a high school diploma are Gallup, New Mexico; Summersville, West Virginia; Natchez, Mississippi; Graham, a town in North Texas; and Marquette, Michigan.

The study characterizes Houston and other regions as “commuter zones.” Each zone encompasses urban, suburban, and rural areas that feed into a single labor market.

As NPR explains, the researchers — Stanford University economist Rebecca Diamond and University of California, Berkeley economist Enrico Moretti — spent four years assembling and crunching data about the finances of 3 million U.S. households to come up with their findings.

“With their treasure trove of data, Diamond and Moretti constructed a cost-of-living index that paints a vivid picture of prices and typical consumption patterns throughout the United States,” NPR says.

That index puts Houston in a good light when it comes to the standard of living for both high school and college graduates.

“When we look at the factors that go into where a person chooses to live and work, overall standard of living and quality of life are critical components,” says Susan Davenport, chief economic development officer at the Greater Houston Partnership. “Houston today offers abundant parks and green spaces with millions of dollars in new investments, a world-class arts and culinary scene that continues to grow in global awareness, and the lowest cost of living among major cities.”

These combined attributes create a quality of life that enables Houston employers to attract and retain a highly skilled workforce, Davenport says. This, in turn, helps Houston woo employers seeking access to that workforce.

“It’s a robust and thriving ecosystem,” she says, “and it continues to work to our advantage.”

Houston entrepreneur, Allie Danziger, wanted to create a program for young professionals looking to gain experience in unprecedented times. Photo courtesy of Ampersand

New Houston career training program is helping young professionals and businesses amid pandemic

a new option

Last March, school districts abruptly closed as the threat of the coronavirus grew. In-person classes were cancelled, graduation ceremonies were held virtually, and the future career plans of new graduates were suspended in uncertainty. Through the incertitude, a Houston-based company formed to offer a path forward for young professionals impacted by a newly changed world.

In the early weeks of the pandemic, Allie Danziger sat down with her husband and tried to imagine what she would tell her children to do if they were graduating college. The University of Texas graduate relished her college experience before founding Integrate, an award-winning marketing firm in Houston.

"I wouldn't want them to go to virtual college and not have the same type of experience we were all fortunate to have," she explains.

Simultaneously, Danziger's email began to overflow with young people looking for advice on how to move forward or questioning a gap year. "I've always loved coaching and mentoring young professionals right out of college," she says.

In her 11 years at Integrate, she had mentored more than 100 interns and first-year employees. After researching gap year programs, Danziger launched a new career training program, Ampersand.

Danziger and her co-founder Scott Greenberg created Ampersand with a mission to democratize access to career-building opportunities by providing mentorship and three one-month internships to young professionals. (Disclaimer: InnovationMap is a part of the Spring 2021 Ampersand program.) The curriculum includes personality assessments, career mapping, one-on-one training, and basic career skills to know as an entry-level employee.

The flexible program includes five hours of curriculum-focused learning and 15 hours of interning, allowing participants with outside engagements and college classes to also participate.

"When I speak to universities all over the country, I always tell them that while I valued my college undergraduate experience, I got so much more out of my internships," she says.

The beta launched in August with a group of ten professionals and ten businesses. Each month, the participants rotate to a position at a different business, allowing them to be exposed to new industries and departments. The program is a flexible 20-hour commitment — five hours of curriculum-based learning and 15 hours of interning — done remotely. While Danziger created the program to serve as a way to be productive during a "gap year" or "gap semester," Ampersand can be balanced with outside activities or college classes.

During Brené Brown's 2020 commencement speech for the University of Texas graduation, she predicted that interviewers would soon tell them, "I see you're a 2020 graduate. That was tough. How did you handle it?"

The quote struck Danziger and "was probably the overall inspiration for this business," she reflects. She feels Ampersand is "a way to put that anxiety into a productive place and actually use the downtime, or use the time that you're considering your options, really mindfully."

"I really believe that it scales way beyond this pandemic," says Danziger. In her research, she saw a lack of career-focused gap curriculums and resources available. "There are no programs that help you determine what the right path for you is—to really do that self-exploration and then apply it to your career path," she explains.

Textbooks and classroom learning are important, but to Danziger, "real-world experience is invaluable." In her research and through first-hand experience, she notes there are "big issues with the higher education industry as a whole not really preparing their students for careers."

At Integrate, Danziger noticed newly-hired graduates would sometimes struggle with "basic things to know for day one," like how to ask for time-off or schedule a calendar invitation. "It ends up frustrating managers while also frustrating the entry-level employees because they're not able to succeed at the pace that they expected to," she says. "These students are graduating with tons of student debt, great skills focused in the major that they chose, but very few of the soft skills that they need in order to be successful professionally," she continues.

Student loan debt in the United States reached $1.7 trillion last year with more than 44 million borrowers; the crisis has exceeded the nation's credit card debt by more than $900 billion. A 2015 study from the University of South Carolina linked student loan debt to poor psychological functioning and stress.

According to the National Center for Education Statistics, one in 10 students have changed their major more than once—a figure that can be correlated to the increasing student loan crisis.

"People are taking fifth and sixth years because they had to change their major, or they move careers after a year of their first job, which then costs them and the company significant dollars in lost wages," says Danziger.

Danziger feels Ampersand also answers the prominent issue of diversity in the workplace.

"If businesses get a more diverse workforce at that very entry-level space, who are prepared and ready to take on the jobs just like anyone else, these interns will grow through the ranks and have significantly more opportunities in management and in the boardrooms," she says.

Young professionals aren't the only beneficiaries of Ampersand. Businesses, too, have reaped the perks of interns hungry for new experiences and a resume boost. From competitive analyses to marketing plans, interns are contributing tasks companies "didn't have time to make it a priority, especially amid the pandemic," says Danziger.

Through weekly one-on-one virtual sessions, the Ampersand team works with the professionals to go over their to-do lists and act as their project managers.

"We do all the mentorship and coaching, so that the business just has to receive the end product," she explains.

"This definitely beats the option of a career day and sets them up to make more informed career choices," Liz Cordell, co-founder and COO at Mak Studio. Cordell, who participated in the first cohort, assigned interns to social media marketing projects her company didn't have the capacity to work on. Knowing the Gen Z and millennial-aged professionals excel social media, she has enjoyed working with interns who've "become a part of the team," despite a remote work environment.

"The training the interns receive with Ampersand prior to joining your team gives them access to fundamental skills, concepts, and tools used in business today. This levels up your interns to be able to meaningfully contribute to your company from day one," says Cordell. As a business owner, she feels the program provides "a unique opportunity to have an intern with professional support."

One Louisiana State University student used Ampersand to discover his creative strengths and land a job offer from one of his internships. At the beginning of the program, he confided in Danziger that he "wasn't feeling motivated to pursue this career accounting," and didn't find enjoyment in his classes.

The student's Ampersand personality assessment identified his inclination to creativity; he participated in a series of internships that included an architecture firm, furniture company, and a finance startup. "He's able to really see how he can keep his accounting degree and apply it to these other career paths. It's just amazing to see how he's blossomed from this," says Danziger.

While the nation prepares for a shift in power, the incoming president has outlined support for workforce training programs that aligns with Ampersand's mission. President-elect Joe Biden plans to make a $50 billion investment into workforce training programs when he takes office. The proposal announces that money will fund partnerships between community colleges, businesses, unions, state, local, and tribal governments, universities, and high schools to identify in-demand skills in and modernize training programs.

Ampersand kicked off its second cohort with 30 professionals and 30 participating businesses from around the country on Jan. 5, and is currently accepting applications for its summer program. She anticipates the growing startup will begin raising a seed round during the first quarter. While Danziger emanates with excitement about the launch and balances her role as President of Integrate, she has big plans for the future of Ampersand.

Danziger dreams of scaling Ampersand to serve as many young professionals and businesses who are interested in participating.

"With that, I really want to be able to bring this to the low-income community so we can fulfill the mission of democratizing access to internships and professional development to everyone," she says.


Ampersand // Professional Development & Internship Programwww.youtube.com

Young professionals can dive into fun travel with this Houston-based company. Photo courtesy of Here and Now Travel

New travel startup plans the perfect vacations for Houston's busy young professionals

GET THERE NOW

Work-life balance for a young professional is hard. There's the dream of travel but the nightmare of planning. Then there's the challenge of working with limited vacation days and finding a friend whose schedule lines up.

To the rescue comes Houston-based Here & Now Travel, which aims to create a vacation free of stress and full of memorable experiences and offers adventurous group travel specifically for young professionals.

When discussing the inspiration for starting their company, cofounder Alex Coleman tells CultureMap that he and his wife and fellow cofounder, Elise, were caught between the benefits and drawbacks of individual versus group travel.

They loved the freedom of solo traveling but not the potential feelings of isolation and vulnerability. When it came to traveling with friends, they enjoyed the bonding and security in a group but not all the work involved with navigating everyone's schedules and preferences during planning.

"We decided to create a travel company that combined the best of both worlds," Coleman says. "A company that gave people the flexibility of going to their desired destinations at their desired time, without losing the experience of traveling with a group of awesome people."

As young professionals themselves, the Colemans also wanted their company to consider the typically low number of vacation days their target clients have. That's why Here & Now trips take advantage of weekends and holidays so participants only have to take a maximum of three days off from work.

Here & Now Travel currently has six trips planned for 2020: two to Costa Rica, two to Colombia, and two to Mexico. On these trips, the itineraries lean towards adventure activities and cultural experiences.

For example, their next trip scheduled for January 9 to January 13 to Costa Rica includes exploring Juan Castro Blanco National Park, zip lining through the rainforest, learning how to make tortillas with a local family, and more.

"We shy away from crowded tourist attractions. We pride ourselves on showing travelers hidden gems of our destinations, be it the hidden Mayan cenote in Tulum where we have to be blessed by the community's Mayan Shaman before entering, or one of the region's largest waterfall in Costa Rica which sits on the land of a small farming family," says Coleman. "Through these tucked away, amazing places, we get to see things others typically don't, and have true interaction with the communities we are visiting.

Each Here & Now package includes private transportation to and from the airport and for the duration of the trip, shared three or four-star accommodation, all breakfasts and lunches, and all entrance fees and itinerary activity costs. Flights, dinners, and the required travel insurance are not included.

If you decide to join one of their trips, you can expect to be in a group of between six and 14 young professionals — with 14 being the absolute max as Here & Now Travel doesn't want to overrun the visited communities or contribute to the overuse of their resources.

"Large groups in charter buses feel clunky and seem like you are trampling or disrupting the destinations you are visiting," says Coleman. "We cap our trips at 14 people, allowing us to be good stewards of the communities we visit, and maintain our feel as a small group of travelers...and not tourists."

Each travel group is also accompanied by a Here & Now host who handles all the logistics as well as a local guide, which is a feature that Coleman believes sets their company apart from others.

"Travelers on Here & Now trips are always led by someone who calls that destination home," he explains. "Our guides have an emotional bond to the places we explore. Their passion and connection to their homes is something that can't be replicated."

Along with employing these local guides, Here & Now Travel works with local drivers, restaurants, and lodging as a way to ensure the money they spend in each community stays in that community.

As a further testament to their commitment to sustainable tourism, Here & Now Travel plans to offset their carbon footprint, which is mainly caused by airline travel, by donating to the nonprofit Trees for Houston in 2020.

The company also has plans to increase their number of trips to once per month and to eventually include European destinations.

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This article originally ran on CultureMap.

Three Houston companies made Fortune's list of best places for millennials. Photo by Katya Horner

Houston energy company with big perks named among best workplaces for millennials

Young life

When it comes to keeping young professionals happy in the workplace, Houston is doing a bang-up job — some companies more than others. A new report released by Fortune magazine and Great Place to Work finds three Houston companies, and a total of 11 Texas companies, among the top 100 Best Workplaces for Millennials 2018.

Making the national list is Hilcorp Energy Company, an organization known for giving its employees huge bonuses, such as $100,000 in 2015 and $50,000 toward a new car in 2010. The Houston-based company has 93 percent of employees saying their workplace is great, likely because of these aggressive financial incentives, which include a revenue sharing program, a bonus program, "helping hands" community assistance programs, and a generous referral incentive, according to the Fortune piece.

Hilcorp, even with its big perks, isn't actually the top Houston company on the national list. That distinction goes to Houston-based David Weekley Homes. The construction and real estate powerhouse, leads the Texas pack at No. 19. Houston's construction/real estate company Camden Property Trust comes in at No. 94, and manufacturing/production firm Hilcorp appears at No. 95.

More than 434,000 survey respondents from Great Place to Work-Certified companies provided input into this annual list. The study analyzed how millennials rated their organizations on more than 50 different metrics defining great workplaces, such as managers' competence, respect and fairness in the workplace, opportunities for meaningful work, executive leadership, and opportunities to innovate and contribute to the organization's success.

The report also analyzed an index of factors where millennials often lag behind other workers, such as access to meaningful work, fair pay, and plans for a future with their organizations. Companies were evaluated as to whether they were creating great workplaces for all millennials — regardless of who they are or what they do for the organization.

Surveys were anonymous, and companies needed to employ at least 50 millennials to be considered. Employees rated the companies on challenges, atmosphere, rewards, pride, communication, and bosses with a numerical ranking. Here's what made the other Houston companies shine:

David Weekley Homes, where 96 percent of employees say their workplace is great, was lauded for offering an employee's children's scholarship program, product discounts, profit sharing, sabbaticals, and even spiritual assistance.

At Camden, where 92 percent of employees say their workplace is great, employees are given apartment discounts, holiday suites, scholarships, tuition assistance, an aggressive stock purchase plan, and even tickets to hot sporting events.

Elsewhere In Texas, familiar San Antonio insurance/financial service brand USAA (United Services Automobile Association) comes in at No. 40, followed by Dallas professional services firm Ryan, Inc. at No. 44 and Dallas' Prime Lending at No. 58.

Austin is represented by tech firm WP Engine, Inc. at No. 61. Dallas' Encompass Home Health checks in at No. 66, while San Antonio transportation company NuStar Energy L.P. follows at No. 69. Abilene makes an appearance with Funeral Directors Life Insurance Company at No. 92, and rounding out the Texas representation is Arlington's Texas Health Resources, Inc. at No. 96.

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This story originally appeared on CultureMap.

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Intuitive Machines to buy satellite maker Lanteris for $800M

space deal

Houston-based aerospace company Intuitive Machines has agreed to buy satellite manufacturer Lanteris Space Systems for $800 million from private equity firm Advent International.

Intuitive Machines co-founder, president and CEO Steve Altemus said the combined revenue of his company and Palo Alto, California-based Lanteris exceeded $850 million as of Sept. 30, and their backlog of orders totaled $920 million.

Until recently, Lanteris operated as Maxar Space Systems. Its origins date back to 1957.

The deal—comprising $450 million in cash and $350 million in Class A shares of Intuitive Machines stock—is expected to close in the first quarter of 2026.

The acquisition “marks the moment Intuitive Machines transitions from a lunar company to a multi-domain space [company], setting the pace for how the industry’s next generation will operate,” Altemus said.

Altemus said the acquisition would enable Intuitive Machines to better compete for Earth orbit, lunar, Mars and deep space projects. Among the opportunities that would open up thanks to the Lanteris deal are the proposed Golden Dome missile defense system and a large lunar lander capable of carrying astronauts, he said.

“The new Intuitive Machines will combine rapid innovation and precision spacecraft production to meet the growing demand for responsive, high-reliability space infrastructure and services,” Altemus said.

Intuitive Machines, founded in 2013, develops lunar landers and provides aerospace services. In 2024, it became the first U.S. company to land a spacecraft on the moon in half a century.

Altemus said Intuitive Machines is already building three satellites for NASA’s near-space network, and it might upsize two more satellites now that it plans to buy Lanteris.

Aside from satellites, Lanteris is developing the power and propulsion element for NASA’s Gateway, a lunar orbiting command module that will support Artemis missions and deep space exploration.


Lanteris was a division of Maxar Technologies, which Advent and minority investor British Columbia Investment Management took private in a 2023 deal valued at $6.4 billion

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Meet 6 mentors who are helping the Houston startup scene flourish

meet the finalists

Few founders launch successful startups alone — experienced and insightful mentors often play an integral role in helping the business and its founders thrive.

The Houston startup community is home to many mentors who are willing to lend an ear and share advice to help entrepreneurs meet their goals.

The Mentor of the Year category in our 2025 Houston Innovation Awards will honor an individual like this, who dedicates their time and expertise to guide and support budding entrepreneurs. The award is presented by Houston City College Northwest.

Below, meet the six finalists for the 2025 award. They support promising startups in the medical tech, digital health, clean energy and hardware sectors.

Then, join us at the Houston Innovation Awards this Thursday, Nov. 13 at Greentown Labs, when the winner will be unveiled. The event is just days away, so secure your seats now.

Anil Shetty, InformAI

Anil Shetty serves as president and chief medical officer for biotech company Ferronova and chief innovation officer for InformAI. He's mentored numerous medical device and digital health companies at seed or Series A, including Pathex, Neurostasis, Vivifi Medical and many others. He mentors through organizations like Capital Factory, TMC Biodesign, UT Venture Mentoring, UTMB Innovation and Rice's Global Medical Innovation program.

"Being a mentor means empowering early-stage innovators to shape, test, and refine their ideas with clarity and purpose," Shetty says. "I’m driven by the opportunity to help them think strategically and pivot early before resources are wasted. At this critical stage, most founders lack the financial means to bring on seasoned experts and often haven’t yet gained real-world exposure. Mentorship allows me to fill that gap, offering guidance that accelerates their learning curve and increases the chances of meaningful, sustainable impact."

Jason Ethier, EnergyTech Nexus

Jason Ethier is the founding partner of EnergyTech Nexus, through which he has mentored numerous startups and Innovation Awards finalists, including Geokiln, Energy AI Solutions, Capwell Services and Corrolytics. He founded Dynamo Micropower in 2011 and served as its president and CEO. He later co-founded Greentown Labs in Massachusetts and helped bring the accelerator to Houston.

"Being a mentor means using my experience to help founders see a clearer path to success. I’ve spent years navigating the ups and downs of building companies, struggling with cash flow, and making all the mistakes; mentoring gives me the chance to share those lessons and show entrepreneurs the shortcuts I wish I’d known earlier," Ethier says. "At Energytech Nexus, that role goes beyond just helping individual founders — it’s about creating a flywheel effect for Houston’s entire innovation ecosystem."

Jeremy Pitts, Activate Houston

Jeremy Pitts serves as managing director of Activate Houston, which launched in Houston last year. He was one of the founders of Greentown Labs in the Boston area and served in a leadership role for the organization between 2011 and 2015. Through Activate, he has mentored numerous impactful startups and Innovation Awards finalists, including Solidec, Coflux Purification, Bairitone Health, Newfound Materials, Deep Anchor Solutions and others.

"Being a mentor to me is very much about supporting the person in whatever they need. Oftentimes that means supporting the business—providing guidance and advice, feedback, introductions, etc," But just as important is recognizing the person and helping them with whatever challenges they are going through ... Sometimes they need a hype man to tell them how awesome they are and that they can go do whatever hard thing they need to do. Sometimes they just need an empathetic listener who can relate to how hard these things are. Being there for the person and supporting them on their journey is key to my mentorship style."

Joe Alapat, Liongard

Joe Alapat founded and serves as chief strategy officer at Houston software company Liongard and chief information officer at Empact IT, which he also owns. He mentors through Founder Fridays Houston Group, Software Day by Mercury Fund, SUPERGirls SHINE Foundation, Cup of Joey and at the Ion. He's worked with founders of FlowCare, STEAM OnDemand, Lokum and many other early stage startups.

"Being a mentor to me means unleashing an individual’s 10x—their purpose, their ikigai (a Japanese concept that speaks to a person’s reason for being)," Alapat says. "Mentoring founders in the Houston community of early stage, high-growth startups is an honor for me. I get to live vicariously through a founder’s vision of the future. Once they show me that compelling vision, I’m drawn to bring the future forward with them so the vision becomes reality with a sense of urgency."

Neal Dikeman, Energy Transition Ventures

Neal Dikeman serves as partner at early stage venture fund Energy Transition Ventures, executive in residence at Greentown Labs, and offices in and supports Rice Nexus at the Ion. He mentors startups, like Geokiln, personally. He also mentored Helix Earth through Greentown Labs. The company went on to win in the Smart Cities, Transportation & Sustainability contest at SXSW earlier this year. Dikeman has helped launch several successful startups himself, most recently serving on the board of directors for Resilient Power Systems, which was acquired by Eaton Corp for $150 million.

"Founders have to find their own path, and most founders need a safe space where they can discuss hard truths outside of being 'on' in sales mode with their team or board or investors, to let them be able to work on their business, not just in it," Dikeman says.

Nisha Desai, Intention

Nisha Desai serves as CEO of investment firm Intention and mentors through Greentown Labs, TEX-E, Open Minds, the Rice Alliance Clean Energy Accelerator, Avatar Innovations and The Greenhouse. She currently works with founders from Solidec, Deep Anchor Solutions, CLS Wind and several other local startups, several of which have been nominated for Innovation Awards this year. She's served a board member for Greentown Labs since 2021.

"When I first started mentoring, I viewed my role as someone who was supposed to prevent the founder from making bad decisions. Now, I see my role as a mentor as enabling the founder to develop their own decision-making capability," Desai says. "Sometimes that means giving them the space to make decisions that might be good, that might be bad, but that they can be accountable for. At the end of the day, being a mentor is like being granted a place on the founder's leadership development journey, and it's a privilege I'm grateful for."

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

Rice, Houston Methodist developing soft 'sleep cap' for brain health research

Researchers and scientists at Rice University and Houston Methodist are developing a “sleep cap” that aims to protect the brain against dementia and other similar diseases by measuring and improving deep sleep.

The project is a collaboration between Rice University engineering professors Daniel Preston, Vanessa Sanchez and Behnaam Aazhang; and Houston Methodist neurologist Dr. Timea Hodics and Dr. Gavin Britz, director of the Houston Methodist Neurological Institute and chairman of the Department of Neurosurgery.

According to Rice, deep sleep is essential for clearing waste products from the brain and nightly “cleaning cycles” help remove toxic proteins. These toxic proteins, like amyloids, can accumulate during the day and are linked to Alzheimer’s disease and other neurological issues.

Aazhang, director of the Rice Neuroengineering Initiative, and his team are building a system that not only tracks the brain’s clearing process but can also stimulate it, improving natural mechanisms that protect against neurodegeneration.

Earlier proof-of-concept versions of the caps successfully demonstrated the promise of this approach; however, they were rigid and uncomfortable for sleep.

Preston and Sanchez will work to transform the design of the cap into a soft, lightweight, textile-based version to make sleep easier, while also allowing the caps to be customizable and tailored for each patient.

“One of the areas of expertise we have here at Rice is designing wearable devices from soft and flexible materials,” Preston, an assistant professor of mechanical engineering, said in a news release. “We’ve already shown this concept works in rigid device prototypes. Now we’re building a soft, breathable cap that people can comfortably wear while they sleep.”

Additionally, the research team is pursuing ways to adapt their technology to measure neuroinflammation and stimulate the brain’s natural plasticity. Neuroinflammation, or swelling in the brain, can be caused by injury, stroke, disease or lifestyle factors and is increasingly recognized as a driver of neurodegeneration, according to Rice.

“Our brain has an incredible ability to rewire itself,” Aazhang added in the release. “If we can harness that through technology, we can open new doors for treating not just dementia but also traumatic brain injury, stroke, Parkinson’s disease and more.”

The project represents Rice’s broader commitment to brain health research and its support for the Dementia Prevention Research Institute of Texas (DPRIT), which passed voter approval last week. The university also recently launched its Rice Brain Institute.

As part of the project, Houston Methodist will provide access to clinicians and patients for early trials, which include studies on patients who have suffered traumatic brain injury and stroke.

“We have entered an era in neuroscience that will result in transformational cures in diseases of the brain and spinal cord,” Britz said in the release. “DPRIT could make Texas the hub of these discoveries.”
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