3 Houston innovators to know this week

who's who

This week's Houston innovators to know include Yared Akalou of Alcove Group, Serafina Lalany,of Houston Exponential, and Patrick Lewis of Sustainability Ventures Group. Photos courtesy

Editor's note: This week's group of Houston innovators you need to know might be pretty familiar to you, however each of them have a new endeavor they are excited to launch — from an energy investment group with a new name to new virtual platforms to benefit entrepreneurs.

Yared Akalou, founder-and-CEO of Alcove Group

Yared Akalou founded IAmOther50 to capture the brand of the freelancer along with their personality and experience. Photo courtesy of Alcove

Yared Akalou describes himself as a designer-focused entrepreneur. As founder-and-CEO of Alcove Group, his latest venture, IAmOther50, is a platform for creatives and freelancers to connect to work. This innovation he's focused on is in light of the growth in jobs that are freelance and remote.

"I am really on a mission," Akalou tells InnovationMap. "I have been talking about the future of work for over a decade now. The paradigm will change to viewing work as a service, so it is important to tell a freelancer's story through a more engaging and novel way." Read more.

Serafina Lalany, chief of staff at Houston Exponential

Serafina Lalany joins the Houston Innovators Podcast to discuss the HTX TechList, which launches this week. Photo courtesy of Serafina Lalany

Serafina Lalany is pinpoint focused on creating resources for Houston innovators through her work at Houston Exponential. Most recently, that's meant creating and launching the HTX TechList, which went live last week. For her, one of the most important benefits the platform will afford the city is access to data about the ecosystem.

"We needed a centralized datasource classifying startups, investors, startup development organizations, and corporate innovators," she says on the Houston Innovators Podcast. "There was not any good resource on the internet that was verified, centralized, and adhered to a data standard." Read more and stream the episode.

Patrick Lewis, managing partner of Sustainability Ventures Group

Houston-based Sustainability Ventures Group is focused on connecting energy companies to innovative, sustainable solutions. Photo courtesy of SVG

As Patrick Lewis started to get a feel for what his network within the energy industry was looking for amid the pandemic, he thought some of the sustainability-focused ventures might be on the back burner.

"We thought we would hear that sustainability in this environment may have slipped down the priority list, but it was the exact opposite," Lewis says. "Pretty consistently across all the operators, sustainability, reducing emissions, and greenhouse gases — those are all even more important today."

This confirmation that the energy industry is committed to innovative sustainability projects led Lewis to rebrand his energy tech investment group from BBL Ventures to Sustainability Ventures Group, or SVG. The investment team focuses on reverse engineering the startup innovation process by sourcing the concerns and goals of the energy companies, then finding solutions from the startup world through reverse pitch competitions and challenges. Read more.

Houston — much like the rest of the world — has a growing freelance economy. A local innovator has created a platform for freelancers to find work. Photo courtesy of Common Desk

Houston entrepreneur creates a new digital platform to help connect freelancers to clients

calling all creatives

By 2027, freelancers will account for the majority of the American workforce — and Houston is already well represented by the freelance space.

According to a recent study, Houston is home to 117,260 skilled freelancers who generated more than $4.1 billion in revenue in 2018. This burgeoning environment for freelancers presents many opportunities for innovations in the tech world, as one Houston entrepreneur has already discovered.

Yared Akalou, founder-and-CEO of Alcove Group and self-described designer-focused entrepreneur, released his third innovation catering to freelancers of the Houston area. His digital solutions platform, IAmOther50, assists freelancers with securing new clients by sharing their personal stories rather than just submitting their professional experience, it uses videos and articles to promote the work of a freelancer and connect them to their next client.

"I am really on a mission," Akalou tells InnovationMap. "I have been talking about the future of work for over a decade now. The paradigm will change to viewing work as a service, so it is important to tell a freelancer's story through a more engaging and novel way."

At first glance, the digital platform seems like a departure for Akalou who in 2017 founded Alcove, a portable laptop case that serves as a private workspace for freelancers to use amid coffee shops or coworking spaces. However, IAmOther50 serves as a distinctly separate yet integral part of his innovation landscape.

"These projects have been a combination of my focus and research," says Akalou. "My new platform works hand in hand with Alcove, supporting the mission to help people stay productive from anywhere."

The digital platform serves to capture the brand of the freelancer along with their personality and experience. It lives at the intersection of popular social media platforms and professional platforms such as LinkedIn, except just for freelancers in the Houston area. Currently, any freelancing professional in the Houston area can join for free by filling out a survey that customizes their goals for their profile.

"IAmOther50 provides information in a contextual way," says Akalou. "We have this guiding principle of delivering value even before the prospective client contacts the freelancer for an interview or potential position. It's about going beyond just a resume of what you've done and showcasing how you add value right now."

Akalou, who is also one of the mentors in The Ion Smart and Resilient Cities Accelerator, is focused on elevating the professional profiles of many freelancers, including those outside the Houston area. He is aiming to grow the platform to a self-service platform that can connect freelancers to clients all over the biggest metropolitan areas soon.


It's not easy getting green. Getty Images

3 tips for a successful crowdfunding campaign

Know before you hit go

Kickstarter is a widely popular crowdfunding platform that helps people to raise money and awareness for their creative projects. While known for product-focused campaigns, musicians to film producers have also achieved success on the platform. In September of 2017, my Houston-based startup GetAlcove.com launched our first kickstarter campaign. While we exceeded our campaign goal, it was a very intense 45 day campaign. Let's consider the statistics:


Yes, almost 70 percent of projects fail. Don't fret. Understanding how to effectively plan and launch your campaign will increase your chances for meeting your campaign goals.

By March 2017, my co-founder and I received enough customer feedback to warrant the pursuit of developing Alcove Workstation™ further. We were attracted to crowdfunding as it presented a viable option for validating our concept with a wider audience while also raising the initial working capital necessary to mass producing Alcove. After researching the various crowdfunding platforms, we decided on Kickstarter as it is well known for launching product-focused campaigns and has a strong brand that we could leverage during our marketing efforts. While we read countless publications on how to prepare for our crowdfunding campaign, our experience on Kickstarter garnered three key lessons.

1. Spend up to one year prepping before launching your campaign.

I can't stress this enough. After we decided to launch, we spent six months engaging with our target audience and obtaining verbal commitments from friends and family and past colleagues to back our project. We also presented at local events and evangelized our brand via social media marketing. In hindsight, we should have spent additional time finalizing the production ready sample of our product prior to launching.

Once you launch your campaign, the clock starts ticking and you'll need deliver fast. Due to a myriad of issues with remote manufacturing, we inevitably missed our original ship date. Fortunately, the kickstarter community is forgiving and recognizes the inherent challenges with bringing a product to market. Even so, I recommend launching your campaign as close to your final concept as possible to reduce unforeseen delays with manufacturing and shipping logistics.

Once you launch your campaign, the clock starts ticking and you'll need deliver fast.

2. Determine which crowdfunding platform is right for your project.

There are four main types of crowdfunding platforms. Kickstarter and Indiegogo are rewards-based whereas platforms like GoFundMe are donation-based. More recently, equity, and debt based platforms like Houston's NextSeed have garnered attention from campaigners seeking alternative methods to raising funds and deferring payment.

Take the time to read about each type and contact each platform for specifics about how they will support your campaign during and after campaign. Indiegogo does a solid job of highlighting their partnerships with vendors that can assist you during different stages of your campaign; offering marketing promotion, direct links to manufacturing vendors, and additional funding options even after your campaign ends.

The next step to determining the right platform for your project is to search for similar "like" products. If you are launching the most revolutionary ear buds on the planet, then you want to ensure people are backing ear buds or similar product on the platform/s you are considering. A simple search on each site will pull up all ear bud projects to date. Then, you can quickly assess the patterns of the most successful vs. unsuccessful campaigns.

3. Launch the right campaign goal, with the right team, at the right time.

This is both important and hard to determine. Let's break it down.

The right campaign goal
The campaign goal is the total dollar amount you want to raise by the end of your campaign. The goal amount can be adjusted once on Kickstarter but I recommend that you keep it low — $5,000-$10,000 — to ensure you meet your goal within two days — three days max. Keep in mind you are competing with four to five thousand live projects at any given time. If you make your campaign goal, Kickstarter's algorithm pushes your project up the list and you have a good shot of being listed or even featured on the front page of Kickstarter's website. If you make your campaign goal too high and don't meet your goal with those couple days, Kickstarter's algorithm pushes your project down the list. If I recall, our campaign went from approximately 115 to 800 after day two. Each day that passes, your project is pushed even further down the list of over 4000 projects. What this means to your project is that unless you have a serious marketing engine behind you, no one will see your project outside of your immediate contact list or followers on social media. This is where hiring the right team of marketers and PR can be invaluable.

The right team
Think of the development of your crowdfunding campaign as a micro-enterprise site that requires the right mix of talent to build out. Funded startups with established teams and products in market, for instance, are launching on Kickstarter as a way to increase market awareness of their new products. For the boot-strapped startups with small teams, leverage your strengths and hire for gaps in skills to ensure you develop the right communications, pricing strategy, and overall layout of your page. To be clear, a production quality video is an absolute must.

The right time
Finally, consider the timing of your launch to align with complimentary events or holidays. If your product is focused on education/learning, the obvious timeframe would be to launch during back to school. Another way to galvanize your target audience is to identify popular conferences for your industry. For our campaign, we aligned with the Tech Disrupt conference in San Francisco and literally went live on Kickstarter directly from our exhibit booth!

While I can not make any guarantees for your campaign's success, I am confident that if you apply these tips, you will be that much closer to achieving your campaign goals.

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Yared Akalou is the founder of Houston-based Alcove.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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