Texas ranks as a top state for female entrepreneurs

women in business

Texas takes a stumble on an annual list that identifies the top states for female founders. Photo via Getty Images

Texas dropped three spots in Merchant Maverick’s annual ranking of the top 10 states for women-led startups.

The Lone Star State landed at No. 5 thanks in part to its robust venture capital environment for women entrepreneurs. Last year, Texas ranked second, up from its No. 6 showing in 2021.

Merchant Maverick, a product comparison site for small businesses, says Texas “boasts the strongest venture capital scene” for women entrepreneurs outside California and the Northeast. The state ranked fourth in that category, with $6.5 billion invested in the past five years.

Other factors favoring Texas include:

  • Women solely lead 22 percent of all employees working for a business in Texas (No. 4).
  • Texas lacks a state income tax (tied for No. 1).

However, Texas didn’t fare well in terms of the unemployment rate (No. 36) and the rate of business ownership by women (No. 29). Other Texas data includes:

  • Average income for women business owners, $52,059 (No. 19).
  • Early startup survival rate, 81.9 percent (No. 18).

Appearing ahead of Texas in the 2023 ranking are No. 1 Colorado, No. 2 Washington, No. 3 California, and No. 4 Arizona.

Another recent ranking, this one from NorthOne, an online bank catering to small businesses, puts Texas at No. 7 among the 10 best states for women entrepreneurs.

NorthOne says Texas provides “a ton of opportunities” for woman entrepreneurs. For instance, it notches one of the highest numbers of women-owned businesses in the country at 1.4 million, 2.1 percent of which have at least 500 employees.

In this study, Texas is preceded by Colorado at No. 1, Nevada at No. 2, Virginia at No. 3, Maryland at No. 4, Florida at No. 5, and New Mexico at No. 6. The rankings are based on eight metrics, including the percentage of woman-owned businesses and the percentage of women-owned businesses with at least 500 employees.

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Based on Houston's number of majority female-owned startups, the city ranks as No. 7 in the country. Getty Images

Houston has the No. 7 most startups owned by women

Female founders

While there's still a gap between men and women when it comes to, well, a lot of things in business, Houston is among the top 10 cities in the United States for women-owned startups.

In an effort to find the metropolitan areas with the most women-owned startups, Seek Capital conducted a study on the largest 50 metro areas using data from the U.S. Census Bureau Annual Survey of Entrepreneurs. In Houston, 26.6 percent of its 10,462 startups are owned by women. When compared to other cities, that percentage ranks the city at No. 17. But the number of Houston's women-owned startups — 2,783, which in total employ 9,378 people — earns it the No. 7 spot in the nation.

Across the country, 24.5 percent of the nation's startups are owned by female entrepreneurs, so — compared to the U.S. — Houston's average is slightly better. The top industry for women-owned businesses nationwide is health care and social assistance, but closer to home, that top industry for businesses owned by women is in professional, scientific, and technical services.

In the study, a "startup" is defined as a company less than two years old and "female owned" means at least 51 percent of the company is owned by women.

Austin came in No. 2 in the study for reportedly having 32.7 percent if its startups owned by women. However, Austin has only 1,433 women-owned startups, according to the report, compared to Houston's 2,783.

Earlier this year, Texas was named the best state for female entrepreneurs, according to Fit Small Business. The methodology for that report included evaluating with four equally weighted factors: general business climate and opportunity, the number of female-owned businesses, economic and financial health, and safety and well-being for women.

CategoryHoustonRankU.S. Totals
Percentage of startups that are female-owned26.6%17th24.5%
Number of female-owned startups2,7837th125,634
Employees at female-owned startups9,37810th511,939
Gross sales/receipts of females-owned startups$1-$5 billion-$56 billion
Most active industry for female entrepreneursProfessional, scientific, and technical services-Health care and social assistance

Chart via Seek Capital.

Chart via Seek Capital.

The Lone Star State provides ample opportunities as well as a booming business economy for female entrepreneurs, a new report found. Pexels

Texas ranks as top state for female entrepreneurs

We're No. 1

Texas is known for being a land of opportunity, but a recent study evaluated how those business opportunities translated to benefitting female entrepreneurs. Turns out, starting a business as a woman in the Lone Star State is a pretty good idea.

Fit Small Business ranked all 50 states based on the business opportunities for women. In the January 8 report, Texas came in No. 1 — up from No. 8 last year. Ohio, Minnesota, Washington, and Alabama rounded out the top five, respectively.

Each state was evaluated by four equally weighted factors: its general business climate and opportunity, the number of female-owned businesses, economic and financial health, and safety and well-being for women.

Texas ranked strongest in its economic and financial health, for which it ranked No. 3 overall, followed by the number of female-owned businesses, for which it ranked No. 5. Texas' general business climate was ranked No. 8 in the study. Where the state stands to improve is in its safety and well-being for women. Texas ranked No. 41 in this category, which factored in cost of living, social support for women, and whether or not the state had a positive environment for women.

"Texas is hands-down one of the nation's top states due to its business-friendly legal and economic climate," the report says. "Put aside having no corporate or income taxes and a high rate of startup growth; startups are flocking to Texas high startup success rate."

American Express' 2018 State of Women-Owned Businesses Report found that women-owned businesses are growing at an impressive rate. The study found that over the past 11 years, the amount of women-owned businesses grew 58 percent — compared to the 12 percent all businesses reportedly increased.

In this study, Texas tied with Utah for second place among the states "where women-owned businesses most increased their economic clout between 2007 and 2018." When the data was broken down into metropolitan areas, Texas had three cities in the top 10: San Antonio at No. 2, Austin at No. 3, and Dallas No. 9.

Graphic courtesy of Fit Small Business

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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