Umbrage, a Houston-based developer of enterprise software, has been acquired. Photo via umbrage.com

A Houston software company is celebrating an exit this month.

Umbrage, founded in 2019, is proving once again that Space City is a software hub. Earlier this month, Founder Will Womble announced that Umbrage has been acquired by Bain & Company.

Umbrage creates custom software for companies by partnering with an internal technology team that makes the products. It’s a “teach a man to fish” method that has brought the company great success in creating software such as Shell’s TapUp app.

Bain & Company works with clients in 64 cities across 39 countries, meaning the global consultancy is positioned to bring Umbrage worldwide.

"Alongside Bain, we can deliver enhanced end-to-end solutions that will position our clients for success and to adapt during waves of disruptive emerging technologies," says CEO Womble in the release.

Bain’s Vector program has advised more than 6,700 digital projects around the world and across industries. It works by creating joint teams featuring Bain’s consulting staff, allowing companies to reach their digital goals themselves, but with a little help, not unlike Umbrage’s own methods. Acquiring Umbrage gives Bain a boost in its ability to help clients on a larger scale.

"Bain's commitment to delivering results with clients requires expanding and enhancing its ability to innovate and industrialize digital solutions," says Arpan Sheth, global leader of Vector, Bain's digital delivery platform. "Joining forces with Umbrage will allow us to develop a best-in-class, craft-centric digital product and venture building studio that will enable our clients to not only develop successful digital strategies, but to also execute on these strategies through world-class software capabilities. Umbrage further enhances Bain's Next solution to support our clients in their business building missions.”

Once the deal is completed, Umbrage will operate independently, but as a branded service line that’s part of Bain Innovation & Design. But existing clients needn’t worry. Umbrage will continue to assist them, including clients in financial services, energy, natural resources, and other industries.

In 2021, Umbrage raised a $2 million round led by Rice Investment Group. Womble previously joined the Houston Innovators Podcast to share how Houston has played a role in the company's growth.

Will Womble founded Umbrage in 2018. Photo courtesy

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Pioneering Houston biotech startup expands to Brazil for next phase

On the Move

Houston biotech company Cemvita has expanded into Brazil. The company officially established a new subsidiary in the country under the same name.

According to an announcement made earlier this month, the expansion aims to capitalize on Brazil’s progressive regulatory framework, including Brazil’s Fuel of the Future Law, which was enacted in 2024. The company said the expansion also aims to coincide with the 2025 COP30, the UN’s climate change conference, which will be hosted in Brazil in November.

Cemvita utilizes synthetic biology to transform carbon emissions into valuable bio-based chemicals.

“For decades Brazil has pioneered the bioeconomy, and now the time has come to create the future of the circular bioeconomy,” Moji Karimi, CEO of Cemvita, said in a news release. “Our vision is to combine the innovation Cemvita is known for with Brazil’s expertise and resources to create an ecosystem where waste becomes opportunity and sustainability drives growth. By joining forces with Brazilian partners, Cemvita aims to build on Brazil’s storied history in the bioeconomy while laying the groundwork for a circular and sustainable future.”

The Fuel of the Future Law mandates an increase in the biodiesel content of diesel fuel, starting from 15 percent in March and increasing to 20 percent by 2030. It also requires the adoption of Sustainable Aviation Fuel (SAF) and for domestic flights to reduce greenhouse gas emissions by 1 percent starting in 2027, growing to 10 percent reduction by 2037.

Cemvita agreed to a 20-year contract that specified it would supply up to 50 million gallons of SAF annually to United Airlines in 2023.

"This is all made possible by our innovative technology, which transforms carbon waste into value,” Marcio Da Silva, VP of Innovation, said in a news release. “Unlike traditional methods, it requires neither a large land footprint nor clean freshwater, ensuring minimal environmental impact. At the same time, it produces high-value green chemicals—such as sustainable oils and biofuels—without competing with the critical resources needed for food production."

In 2024, Cemvita became capable of generating 500 barrels per day of sustainable oil from carbon waste at its first commercial plant. As a result, Cemvita quadrupled output at its Houston plant. The company had originally planned to reach this milestone in 2029.

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This story originally appeared on our sister site, EnergyCapitalHTX.

Texas universities develop innovative open-source platform for cell analysis

picture this

What do labs do when faced with large amounts of imaging data? Powerful cloud computing systems have long been the answer to that question, but a new riposte comes from SPACe.

That’s the name of a new open-source image analysis platform designed by researchers at Baylor College of Medicine, Texas A&M University and the University of Houston.

SPACe, or Swift Phenotypic Analysis of Cells, was created to be used on standard computers that even small labs can access, meaning cellular analysis using images produced through cell painting has a lower barrier to entry than ever before.

“The pharmaceutical industry has been accustomed to simplifying complex data into single metrics. This platform allows us to shift away from that approach and instead capture the full diversity of cellular responses, providing richer, more informative data that can reveal new avenues for drug development,” Michael Mancini, professor of molecular and cellular biology and director of the Gulf Coast Consortium Center for Advanced Microscopy and Image Informatics co-located at Baylor College of Medicine and TAMU Institute for Bioscience and Technology.

SPACe is not only accessible because of its less substantial computational needs. Because the platform is open-source, it’s available to anyone who needs it. And it can be used by academic and pharmaceutical researchers alike.

“The platform allows for the identification of non-toxic effects of drugs, such as alterations in cell shape or effects on specific organelles, which are often overlooked by traditional assays that focus largely on cell viability,” says Fabio Stossi, currently a senior scientist with St. Jude Children’s Research Hospital, the lead author who was at Baylor during the development of SPACe.

The platform is a better means than ever of analyzing thousands of individual cells through automated imaging platforms, thereby better capturing the variability of biological processes. Through that, SPACe allows scientists an enhanced understanding of the interactions between drugs and cells, and does it on standard computers, translating to scientists performing large-scale drug screenings with greater ease.

"This tool could be a game-changer in how we understand cellular biology and discover new drugs. By capturing the full complexity of cellular responses, we are opening new doors for drug discovery that go beyond toxicity,” says Stossi.

And the fact that it’s open-source allows scientists to access SPACe for free right now. Researchers interested in using the platform can access it through Github at github.com/dlabate/SPACe. This early version could already make waves in research, but the team also plans to continually improve their product with the help of collaborations with other institutions.