Houston startup raises $10M, A&M names TMC campus, and more innovation news

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The latest Houston innovation news includes a name for the burgeoning Texas A&M University campus in the Texas Medical Center. Photo courtesy of TAMU

Houston's innovation ecosystem has been booming with news, and it's likely some might have fallen through the cracks. From a Texas university naming its burgeoning new campus to a Houston SaaS startup with fresh funds, here are some short stories in Houston innovation.

ThoughtTrace raises $10M series B

ThoughtTrace has received investment from Chevron Technology Ventures. Photo via thoughttrace.com

ThoughtTrace Inc., a Houston-based software-as-a-service startup closed a $10 million series B round led by Canadian venture capital fund McRock Capital with contribution from Houston-based Chevron Technology Ventures.

"Chevron Technology Ventures (CTV) pursues externally-developed technologies and new business solutions that have the potential to enhance the way Chevron produces and delivers affordable, reliable and ever-cleaner energy," says Barbara Burger, president of CTV, in a release. "ThoughtTrace fits that mandate with the potential to automate the complex, time-consuming, and document-intensive workflows required for our ongoing business operations."

ThoughtTrace's software quickly analyzes documents and contracts and produces results at a fraction of the cost and time of traditional methods. With the fundraising deal, Scott MacDonald, McRock's co-founder and managing partner, will join ThoughtTrace's Board of Directors.

"We are extraordinarily excited to have both McRock and Chevron join the team. McRock brings a great background in the industrial space, which we see as a great fit. In the case of Chevron, they went from being a new customer in 2019 to an investor in 2020," says Nick Vandivere, ThoughtTrace CEO, in a release.

"With the new capital raise, ThoughtTrace will accelerate its investment in creating AI with unparalleled speed and accuracy, grow strategic partnerships and platform integrations, and add to its existing team of talented professionals, all of which will bring further value to the growing ThoughtTrace customer-base," Vandivere continues.

Texas A&M names its Texas Medical Center campus

The new campus will be called Texas A&M Innovation Plaza. Photo courtesy of Texas A&M University System

After announcing its plans for a $546 million medical complex in Houston's Texas Medical Center in February, Texas A&M University has released the name of the 5-acre campus rising at the intersection of Holcombe Boulevard and Main Street: Texas A&M Innovation Plaza.

The project will be completed in phases. The first phase, which will open later this year, is a renovation of an 18-floor building at 1020 Holcombe Blvd., which will to be the new home for EnMed, a dual degree program that produces both a master's in engineering and a medical degree.

"EnMed is just the first example of innovation that Texas A&M System intends to bring to the Texas A&M Innovation Plaza," says Chancellor John Sharp in a news release. "We are excited to have such a visible location in the Texas Medical Center."

Rice Business Plan Competition lays out virtual plans

The competition must go on. Photo via rbpc.rice.edu

This year's Rice Business Plan Competition, which was planned for March 26 to 28, was canceled due to COVID-19, but the Rice Alliance for Technology and Entrepreneurship has decided to offer up an alternative: A virtual RBPC. Forty two student teams will compete over three virtual events.

  • Elevator Pitch Competition on June 17 (Open to the public): Each team will deliver 60-second pitches.
  • Round 1 on June 18 (Open to startups and judges only ): Each team will deliver 10-minutes to pitch to a panel of judges followed by Q&A.
  • Live finals on June 19 (open to the public): The seven finalists will pitch to the judges, and following a round of questions from judges, the winners and prizes will be announced.

Two health care educational institutions team up for new program

Xavier University and Baylor College of Medicine have launched a collaborative medical track. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

Louisiana's Xavier University and Baylor College of Medicine in Houston have joined forces to allow Xavier students a smooth transition into Baylor's graduate programs. Xavier students, including traditionally underrepresented minorities — according to a press release — will have the opportunity to apply for the program in November. Three students will be selected for the program, which facilitates acceptance into the medical school.

"Our commitment at Baylor College of Medicine to diversity and inclusion creates the best environment for success across our mission areas of healthcare, research, education and community outreach," says Dr. Paul Klotman, president, CEO and executive dean of Baylor College of Medicine, in the release. "This important collaboration with Xavier University will strengthen this commitment, and I look forward to welcoming students from this new partnership into the Baylor family."

Klotman continues to express how inclusiveness is a priority for BCM and for this partnership.

"We live in a world where healthcare is changing and evolving," says Dr. Anne McCall, provost and senior vice president for Academic Affairs at Xavier, in the release. "This partnership will further equip our students with the diverse tools and training that they'll need to foster equity in the medical field and compete on an international level."

University of Houston begins offering virtual tours for perspective students

Potential UH Cougars can get the 411 on campus via a virtual tour tool. Photo via uh.edu

Before COVID-19 sent everyone home and canceled gatherings, classes, and events across the world, the University of Houston was already working on a way for potential students to tour and learn more about the campus. Now, in light of the pandemic, UH has released this virtual tour offering complete with live interaction from UH student ambassadors.

"I'm really excited about the live component we just added because prospective students can ask questions just like during a face-to-face campus tour and that interaction is invaluable," says Mardell Maxwell, executive director of UH Admissions, in a release. "UH is so committed to access, and we see this as a great opportunity not only for students in Houston and Texas, but for those coming from out of state. We are opening up access to campus across the world."

Anyone can sign up for a tour online through the university's website.

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New UH survey reveals concerns over AI data center growth in Houston

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A new report out of the University of Houston shows that area residents remain wary of the long-term effects of operating data centers.

The recent survey from the University of Houston’s latest SPACE City Panel, conducted by the Center for Public Policy at the Hobby School of Public Affairs, shows that while 85 percent of Houston-area residents use AI, nearly 63 percent oppose the construction of AI data centers within 1 mile of their homes.

Respondents’ concerns centered around data centers’ high energy demand and the area’s power grid reliability. According to the survey, 32 percent of residents who oppose local data center projects would be more likely to support the centers if they relied on renewable energy over fossil fuels.

“Respondents understand that AI can bring economic and educational benefits, but they are also concerned about the physical infrastructure needed to fuel AI, especially data centers,” Soran Mohtadi, post-doctoral fellow at the Hobby School and a researcher on the report, said in a news release. “This physical infrastructure demands more electricity and water, leading to environmental impacts.”

Experts estimate that 6.5 gigawatts of data center capacity will be added to the Texas grid by 2030. And Houston’s data center capacity is predicted to more than double by 2028.

The Electric Reliability Council of Texas also projects electricity demand could reach 218 gigawatts by 2031, which would be more than double the record peak set in August 2023. Data centers are expected to account for 86 gigawatts of that new demand.

Survey respondents also said they are concerned about the state's future water supply, given the large amounts of water that data centers need to stay cool.

In terms of who’s responsible for that issue, 57.6 percent of respondents said they put the onus on Texas lawmakers, while 31.5 percent say tech companies should be responsible.

Additionally, more than 75 percent of respondents believed that data center developers and technology companies—not residents—should bear the cost of infrastructure upgrades to support data centers.

“Every decision legislators make has implications on residents’ everyday lives and local infrastructure now and in the future,” Maria P. Perez Arguelles, lead researcher on the report and research assistant professor at the Hobby School, added in the news release. “This issue is going to become more important in years to come, so this is just the beginning.”

Read the full report here.

Houston-born Cemvita makes breakthrough in sustainable fuel production

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Houston-based biotech company Cemvita announced that it recently reached a critical milestone in the development of its FermOil product, which can be used to create Sustainable Aviation Fuel (SAF) and other renewable fuels at industrial scale.

The company shared in a news release that it completed a 75,000-liter industrial fermentation run at Belgium's Bio Base Europe Pilot Plant.

The campaign achieved target technical metrics for the production of FermOil, Cemvita’s renewable natural oil (RNO). FermOil is produced from industrial crude glycerin, an industrial byproduct, as opposed to traditional sugar-based feedstocks used in many bio-oil fermentation processes. It's designed to be a drop-in feedstock for creating SAFs.

Cemvita had previously advanced its FermOil production process through multiple scale-up stages before successfully reaching the 75,000-liter demonstration campaign, according to the company.

“This is not just a fermentation milestone,” Moji Karimi, CEO at Cemvita, said in the release. “It is a blueprint for how existing industrial infrastructure can evolve into circular bioeconomy infrastructure. Every biodiesel plant generating crude glycerin is a potential platform for renewable natural oil production.”

The milestone also supports the deployment of Cemvita’s industrial biomanufacturing platform, FermWorks, which integrates with existing energy and industrial infrastructure to turn waste carbon streams into SAFs and other materials. According to the release, Cemvita plans to move forward with commercial deployment discussions with partners in Brazil, Europe and in the UK. Cemvita already has a partnership with the Brazilian sustainable research institution REMA.

“We are proud to support innovative companies like Cemvita in scaling breakthrough industrial biotechnology solutions,” Hendrik Waegeman, head of business operations at Bio Base Europe Pilot Plant, added in the release. “Successfully operating at the 75,000-liter scale using a feedstock such as crude glycerin highlights both the maturity of the technology and the quality of the scale-up execution achieved by the Cemvita team.”

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Eli Lilly scoops up Houston biotech startup in $300 million deal

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Pharmaceutical giant Eli Lilly has acquired Houston biotech startup CrossBridge Bio, which develops antibody-drug conjugates for cancer, in a deal worth up to $300 million. The deal was celebrated by TMC Venture Fund and the University of Texas Health Science Center at Houston last week.

CrossBridge, founded in 2023, is developing ADCs based on research by Kyoji Tsuchikama and Zhiqiang An, both of UT Health Houston. Tsuchikama is an associate professor of medicinal chemistry and a globally recognized ADC pioneer, and An is a professor of molecular science and vice president of drug discovery.

Antibody-drug conjugates (ADCs) are a potent combination of targeted therapy and chemotherapy that kills cancer cells while saving healthy tissue.

Clinical trials for CrossBridge’s primary ADC candidate, CBB-120, are expected to start this year, pending approval from the U.S. Food and Drug Administration (FDA).

“I’m proud of how well our team has executed and advanced our platform in such a short time since the company’s founding,” Michael Torres, co-founder and CEO of CrossBridge, said in a news release. “By becoming a part of Lilly, a leader in patient-focused therapeutic development, we are well-positioned to further accelerate the clinical potential of this approach.”

Under the Lilly deal, CrossBridge shareholders were expected to receive an upfront payment along with a follow-up payment based on the achievement of certain milestones.

In 2024, CrossBridge closed a $10 million seed round. Among the investors in CrossBridge are the Texas Medical Center Venture Fund, CE-Ventures, Alexandria Venture Investments, Portal Innovations, Linden Lake Labs, and the Cancer Prevention and Research Institute of Texas (CPRIT). It was formed in TMC Innovation’s Accelerator for Cancer Therapeutics program."Built within the TMC ecosystem, CrossBridge Bio grew with the support, funding, and resources that helped shape its trajectory. TMC led the company's early financing and watched it evolve from its earliest days to its acquisition by Eli Lilly," William McKeon, president and CEO of the Texas Medical Center, shared in a LinkedIn post. "[This is a] strong reminder that breakthrough science and the right early backing can change what’s possible."
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