This week's innovators to know in Houston includes Ayse McCracken of Ignite Healthcare Network, Philipp Sitter of VIPinsiders, and Diane Yoo of Medingenii. Photos courtesy

Editor's note: In today's Monday roundup of Houston innovators, I'm introducing you to three innovators — from health care investing to marketing technology — all making headlines in Houston this week.

Ayse McCracken, founder and board chair of Ignite Healthcare Network

Ayse McCracken joins the Houston Innovators Podcast to discuss women in health care and Ignite Madness. Photo courtesy of Ignite

When the pandemic hit and shut down businesses across the world, Ayse McCracken knew immediately what group of people were likely going to be the most affected: Women in health care. It just so happens that her nonprofit organization, Ignite Healthcare Network, exists to serve this same group of people, so she got to work on creating online events that were intentional and meaningful.

"With COVID, it has only escalated the importance of our work, so we've elevated our voices through our webinar series," McCracken says on this week's Houston Innovators Podcast.

This week, Ignite's virtual startup competition concludes with the finals. She shares more about the program and Ignite's mission on the episode. Click here to read more and stream the episode.

Philipp Sitter, founder of VIPinsiders

Restaurateur Philipp Sitter launched VIPinsiders last year. Photo courtesy of VIPinsiders

Restaurants have undoubtedly suffered due to loss of business during the shutdown, but they face an uphill battle back to normalcy, and restaurateur Philipp Sitter knew his tech tool could help. He created VIPinsiders as a marketing tool to reach customers in a data-driven way.

"The restaurant gets to know me [the customer], it understands how often I visit, it also gets to reward my visitation," explains Sitter. "Most importantly, it reminds me to come back when I haven't visited in a while."

Data recorded by VIPinsiders shows that 48 percent of users visit restaurants with the platform "more often" in the first 90 days. Click here to read more.

Diane Yoo, managing partner at Medingenii

Diane Yoo, who was hospitalized due to COVID-19 earlier this year, created a VC fund that's investing in health tech solutions for the disease. Photo courtesy of Medingenii

Just a few weeks after being hospitalized from COVID-19, Diane Yoo was investing in a medical device startup that could have made a world of difference to her recovery. After closing its initial fund, Medingenii invested in several Houston health startups including Vitls, a wearable device that can track and send vitals remotely.

"The pandemic has really validated some of the business models we're invested in," she tells InnovationMap.

Now, fueled by her first round of success and eager to advance other life-changing technologies, Yoo is looking toward a second fund. Click here to read more.

A Houston restaurateur and tech founder is giving the food and restaurant business a new marketing opportunity with VIPinsiders. Photo by Andrea Piacquadio from Pexels

Houston entrepreneur's mobile platform brings gains to small restaurant chains

tapping into tech

Food is the way to a Houstonian's heart. With critically-acclaimed cuisine and an abundance of diversity, Houston is the South's culinary pride. COVID-19 has now stirred uncertainty in a once definitive piece of the city's culture, and restaurateurs are looking for solutions. For Philipp Sitter, CEO of VIPinsiders, artificial intelligence is a step in the right direction.

Sitter holds many titles: CEO of KB Restaurant Group, President of EggHaus and King's Bierhaus — and now, tech founder. In 2019 he launched VIPinsiders, "a rewards program that uses artificial intelligence (AI) to understand the customer on an individual journey," he explains.

"I was born into the restaurant industry," says Sitter, as he remarks on immigrating from Vienna as a child and opening the first King's Biergarten in Pearland in 2011. As a fifth-generation restaurateur, he is familiar with "the love and pain of the industry." When he took on the challenge of marketing his family's "obscure German restaurant behind a car wash in Pearland," he became "obsessed" with the trade.

Philipp Sitter launched VIPinsiders last year. Photo courtesy of VIPinsiders

After building excitement around EggHaus, the Instagrammable haven that's attracted both breakfast lovers and influencers, Sitter wanted to find a way to build the same buzz at his other restaurants using technology.

Going mobile

From Starbucks Rewards' gold stars to Chick-Fil-A One, reward programs have been tested and utilized by the Goliaths of the restaurant industry for years.

When looking at the cost of building a mobile app like Starbucks, he determined it to be impossible.

"We're talking about millions that go into developing technology. What restaurant is going to be able to afford something like that?" he asked.

The plan soon crystallized: Sitter decided to create a mobile platform that uses AI to personalize unique offers and experiences for customers while taking the responsibility from the shoulders of restaurant owners with smaller, multi-unit concepts. By developing and scaling the mobile platform by providing its services to other businesses, "then it would all of the sudden become affordable for everybody," he realized.

Deciding to create a mobile platform was the easy part.

"I wasn't born with the emotion of fear in business," shares Sitter, who has dabbled in obscure endeavors from washing cars to flipping classic cars on eBay.

After formulating the VIPinsiders concept, he hired a team of developers to "use the psychology of everything I've learned in marketing and put it into a technology platform," he explains.

The user experience

Each client gets a tailor-made approach, ensuring the rewards and loyalty features are made to fit the restaurant. The VIPinsiders staff builds custom mobile platforms for its small and medium-sized restaurant chain clients that utilize the restaurant's branding, menus and events for $299 per month.

"We got through a discovery call in which our team will actually build the rewards journey for them and show it to the business owner for approval," explains Sitter, "We don't want to give the owners and managers a homework assignment."

Once the platform is approved, Sitter's team trains restaurant owners. In-house copywriters and designers then develop print material for the restaurant to cross-promote the rewards program.

According to VIPinsiders' internal data, 95 percent of users find the app "easy to use." Using QR technology, customers can sign up by scanning a QR code rather than downloading an app.

"The restaurant gets to know me [the customer], it understands how often I visit, it also gets to reward my visitation," explains Sitter. Rather than a one-size-fits-all reward program, the platform is meant to showcase different menu items and offerings.

"Most importantly, it reminds me to come back when I haven't visited in a while."

Data recorded by VIPinsiders shows that 48 percent of users visit restaurants with the platform "more often" in the first 90 days.

Text message marketing 

When stay-at-home orders first took effect in Harris County, many business owners could not update their business hours or post new content on the Google My Business platform due to the site's halted review process during COVID-19.

The issue left business owners with one less form of contact, creating a vulnerability in customer communication. Social media marketing doesn't quite come to the rescue either, with Facebook's algorithm showing an average of 5.5 percent of a brand's following will see its post.

To Sitter, text messaging is "the next frontier."

Due to COVID-19, VIPinsiders recently ran a promotion to provide free platform use and unlimited text capabilities for a limited time to restaurants. "We've gotten a lot of incredible emails and feedback saying thank you for letting us use this and helping us [get] back our business," says Sitter.

"It's time for all of us to take our power back, to own our customer [data] and be able to talk with them directly and not have to pay the middleman [like social media companies] and really have the relationship that customer opted in for," says Sitter.

As one of the first mobile platforms approved by the Texas Alcoholic Beverage Commission, restaurant clients can extend happy hour offerings and provide customers with free alcoholic beverages.

At King's Bierhaus, Sitter was able to deploy an alcohol-to-go offer via text message that resulted in $40,000 of bottled King's Whiskey sold.

"I was able to sell that because I was able to text my customers directly," Sitter says.

Clients outside of Sitter's own properties also see growth. Ninety-three percent of restaurants using the VIPinsiders platform reported an increase in sales.

"I would absolutely recommend other operators to sign up for VIPinsiders because it has increased our sales, our guests love it, and the support we get from them makes it effortless," explains Usman Dhanani, President of Operations for Cyclone Anaya's Tex-Mex Kitchen, in a VIPinsiders testimonial video.

El Toro, a Mexican restaurant chain with six Texas locations, generated an estimated additional $735,000 in sales with a total of more than 35,000 additional customer visits, according to VIPinsiders data.

"The biggest brands in the world and celebrities lead a charge into marketing initiatives," says Sitter, "A company like ours will bring that to small businesses and make it affordable for them so they can compete at the highest level."

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7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”