A COVID-19 research breakthrough out of a Texas university comes from unlikely source

have you heard the one about the llama?

COVID-19 antibody research coming out of the University of Texas stars an unlikely participant: A llama named Winter. University of Texas at Austin/Facebook

In the race to find a treatment for the novel coronavirus, researchers at the University of Texas at Austin have announced a potential breakthrough — thanks to a llama.

Scientists from Texas' flagship university who have been collaborating with the National Institutes of Health and Ghent University in Belgium identified an antibody treatment that could potentially neutralize the virus that causes COVID-19.

The researchers detail their work in the May 5 edition of Cell, a scientific journal.

"This is one of the first antibodies known to neutralize SARS-CoV-2," said Jason McLellan, associate professor of molecular biosciences at UT Austin and co-senior author of the paper, in a release. (FYI, SARS-CoV-2 is referring to the virus that causes COVID-19.)

Using a Belgian llama named Winter, scientists were able to identify two antibodies the animal produces when it comes into contact with a foreign body (such as the coronavirus). The first is similar to a human antibody and the second is much smaller, about one-quarter of the size of the other.

This is Winter. Photo courtesy of University of Texas at Austin

Researchers were able to link two copies of this special llama antibody to create a new antibody. This new antibody binds tightly to a key protein on the coronavirus germ that causes COVID-19 and could possible be nebulized and put into an inhaler.

"That makes them potentially really interesting as a drug for a respiratory pathogen because you're delivering it right to the site of infection," said Daniel Wrapp, a UT graduate student in McLellan's lab and co-first author of the paper.

Unlike vaccines, which can take up to two months to take effect, antibody treatment can be used in more vulnerable populations as a way to fight off the virus.

"Vaccines have to be given a month or two before infection to provide protection," McLellan said. "With antibody therapies, you're directly giving somebody the protective antibodies and so, immediately after treatment, they should be protected. The antibodies could also be used to treat somebody who is already sick to lessen the severity of the disease."

From here, research turns to preclinical studies, using hamsters and primates for testing. If successful, they will move onto humans.

If you're wondering just how a group of researchers living in different parts of the globe were able to make this discovery seemingly overnight, that's because they've actually been working on it since 2016, when Winter was just 9 months old.

The experiment began as a way to develop vaccinations for two earlier versions of the coronavirus: SARS-CoV-1 and MERS-CoV. Their years of research allowed the scientists to pivot in recent months to isolating the protein in COVID-19.

As for Winter, she's now 4 years old and still lives with about 130 llamas on a farm in Belgium, likely unaware of her contribution to potentially altering the course of COVID-19 forever.

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This article originally ran on CultureMap.

Coding camps continue to grow and expand in Houston. The most recent comes from the University of Texas. Getty Images

UT coding camp emerges in Houston as the city grows its tech and innovation ecosystem

Up to code

As Houston's innovation ecosystem grows, the need for tech talent grows too. It's why the University of Texas and workforce accelerator Trilogy Education decided to bring a series of coding boot camps designed to teach Houstonians the skills they need to excel in the fast-paced world of the tech economy to town.

"Too many working adults lack the skills to succeed in the digital economy," says Liliya Spinazzola, the senior director for professional education and strategic initiatives at the Texas Extended Campus of The University of Texas at Austin. "And that means that employers are lacking a talent pool."

The Houston Coding Boot Camp aims to change all that. The 24-week sessions teach web development and coding skills, allowing adults to take classes even as they're working. That kind of flexibility helps them increase their knowledge as they continue to build career paths.

Houston's seen a good amount of growth when it comes to new coding camps. Digital Crafts, for instance, grew from an inaugural class of eight students to 125 people in just two years. Women Who Code saw a need for female coders in Houston to have a network, and now the city has a newly launched chapter.

Student success
So far, 260 students have completed the programs, going on to work at companies such as JP Morgan, IBM, and Deloitte.

One of those is Rebecca Gemeinhardt, now a full stack developer at Shell. She graduated with her bachelor's in graphic arts from the Kansas City Art Institute in 2017, and found that she missed being in a classroom. When she started the boot camp, she was immediately drawn to the challenge the subject matter offered, as well as the flexible schedule.

"The boot camp was just as formidable as the curriculum promised but extremely fulfilling," she says. "Going into boot camp, I didn't tell anyone I was doing it — what if I struggled and couldn't get through it? I kept it a secret until I found the confidence to identify as a developer."

Once she completed the program, she was hired at Shell.

"My life had changed so much in just six months but definitely for the better," Gemeinhardt says. "By focusing on the ability to adopt new technologies, [the coding boot camp instructors] left us with the invaluable skill of being adaptable and fast-learning full stack developers. This has helped me immensely at my current position as we are always incorporating new languages to our architecture depending on individual project needs."

Filling the need
Spinazzola says the camps deliberately try to create environments that foster the level of problem solving and exploration Gemeinhardt describes. The program partners with employers to discover what skills are most needed, and tailors the curriculum to dovetail with them. She says the skills most in demand right now are coding, cyber security, IT project management, and digital marketing.

"We also look at job description data here in Texas to see what skills are listed," she says. "And while students are in the program, we have a robust network that engages with them upfront, talking to them about what jobs are out there. And we host career fairs where they can show off their portfolios and discuss their skills set with potential employers."

Spinazzola says that students come from all walks of life and employment backgrounds, and that 26 percent of the participants are women. With 25 students per boot camp session, the small classes make for deep instruction. UT offers between three and fours sessions in Houston each year. She says that she finds participants are looking to either break into the tech sector, learn new skills or re-train to be able to advance their careers. The average age of students is somewhere in the low-30s, she says.

"We had a student who owned a cooking school and wanted to start a new career," she says. "[Rebecca] trained as a graphic artist and wanted to be a developer. One student shut down his medical practice and says that he wanted to learn coding so that he could go work for a pharmaceutical company. To me, that's the beauty of this program. These skills are in demand, and our students are able to take what they already know and enhance their abilities to be able to take on new career paths."

The University of Texas System scooted up three spots from 2017. University of Texas at Austin/Facebook

University of Texas ranks as one of the world's most innovative schools

Hook 'em

A new ranking from Reuters has placed the University of Texas System among the world's most innovative universities.

According to an October 11 release, the Reuters Top 100: The World's Most Innovative Universities "identifies and ranks the educational institutions doing the most to advance science, invent new technologies and power new markets and industries." The UT System ranked No. 6 out of the 100 best in the world. The 2018 ranking is a jump up from its No. 9 spot in 2017.

In addition to the flagship University of Texas at Austin, the system is comprised of seven other public universities across the state as well as six health institutions. Reuters notes that because of how the UT System reports on innovation, it assessed the entire enterprise rather than individual universities.

As a whole, the UT System boasts an impressive number of accolades that helped it scoot up three spots. As Reuters notes, chief among these accolades is the National Science Foundation's $60 million grant to the Texas Advanced Computing Center at the University of Texas at Austin to build a supercomputer and the system's $2.7 billion in annual research expenditures. (Not to mention numerous Nobel Laureates among both faculty and alumni.)

Overall, the U.S. dominated the list, claiming 46 out of the 100 spots. Rounding out the top 10 for 2018 is: No. 1, Stanford University; No. 2, Massachusetts Institute of Technology; No. 3, Harvard University; No. 4, University of Pennsylvania; No. 5, University of Washington; No. 7, Belgium's KU Leuven, No. 8, U.K.'s Imperial College London; No. 9, University of North Carolina at Chapel Hill; and No. 10, Vanderbilt University.

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This story originally appeared on CultureMap.

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Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

Texas foundation makes massive $180M donation to Galveston hospital

historic gift

The University of Texas Medical Branch in Galveston (UTMB) has accepted a staggering $130 million grant from the Sealy & Smith Foundation, which, combined with the $50 million that the foundation donated in 2025 to establish the Department of Cardiovascular Medicine, is the largest bequest in UTMB history.

The grant will go to grow cardiovascular imaging, diagnosis, and treatment at UTMB by establishing an inpatient cardiovascular hub on the sixth floor of Jennie Sealy Hospital. In honor of the donation, the department is being renamed the Sealy Heart and Vascular Institute.

“The Sealy & Smith Foundation has a long history of investing in initiatives that transform health care for the people of Galveston and beyond,” said John Kelso, president of The Sealy & Smith Foundation Board of Directors. “We believe the Sealy Heart & Vascular Institute has the potential to redefine cardiovascular care in our region by bringing together exceptional physicians, advanced technology, innovative research and a commitment to improving patient outcomes. This additional investment reflects our confidence in UTMB’s vision and our belief that the Institute will have a lasting impact for generations to come.”

The Sealy & Smith Foundation was established in 1922 by John Sealy II and his sister Jennie Sealy Smith. Bolstered by the Sealy fortune built on shipping, oil, banking, and railroads, the Foundation has donated more than $1.2 billion to UTMB over the last century, linking the family legacy to healthcare, teaching, and research. It was John Sealy Sr. who contributed the initial $50,000 to build a hospital on the island, which opened right alongside the new medical school created by the state legislator in what was then Texas's largest and most economically powerful city.

Since then, the Foundation has helped grow UTMB into a world-class hospital. The cardiovascular care especially is well-regarded, making the 2025 Newsweek/Statista List of America's Best Hospitals.

“This extraordinary investment reflects The Sealy & Smith Foundation’s unwavering commitment to improving health and advancing medical excellence,” said Dr. Jochen Reiser, UTMB president and CEO of the UTMB Health System. “The partnership between UTMB and The Sealy & Smith Foundation is very strong. Built on generations of shared vision and trust, it continues to redefine what an academic health system can achieve. Together, we are building one of the nation’s premier cardiovascular programs integrating exceptional patient care, groundbreaking research, innovation and world-class education to improve the lives of patients throughout Texas and beyond.”

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This article originally appeared on CultureMap.com.

UTHealth Houston team joins NASA initiative to protect border drinking water

water watch

Climate change means far more to public health than living with hotter days. Transformations in our weather are contributing to challenges in accessing safe drinking water in some communities.

One of the most dire situations is along the US–Mexico border. The National Aeronautics and Space Administration (NASA) is seeking to address that issue with its Water Quality Applications program. An 11-researcher project led by a UTHealth Houston School of Public Health faculty member has been selected to participate.

“Drinking water is one of the most fundamental public health protections, but producing safe drinking water involves a delicate balance,” Yun Hang, assistant professor of environmental and occupational health sciences, said in a news release. Her team’s proposal was one of 93 that were submitted for funding through NASA’s Research Opportunities in Space and Earth Sciences (ROSES)-2025 program.

This is the first time that NASA has worked with a team devoted to water quality applications. The group, which includes researchers from across the nation, will use satellite observations of Earth, as well as hydrologic modeling, to potentially anticipate and act on water quality conditions as they change. Challenges addressed over the course of the three-year program, which kicked off in June, might include problems with water quality due to climate variability and increased pressure on water resources.

Hang’s team will focus on a pair of borderlands: Paso del Norte and the Rio Grande Valley.

“Working closely with El Paso Water ensures that our research addresses real operational needs while helping utilities better prepare for climate-related water quality changes and continue providing safe drinking water to communities across the Texas border region,” Hang added in the release.

She and the team will use data gathered by NASA on both past and future Earth-observing missions, which will allow them to track environmental changes that may affect source water quality. Combined with past water treatment records and hydrologic models, the team will also utilize artificial intelligence to develop predictive tools that aim to stop issues before they become larger hurdles to water safety.

Another one of the project’s goals is to create visualization tools and source water summaries that can be utilized by those without scientific expertise. The tools will be produced in English and Spanish to further broaden their accessibility.

The hope is that the materials made by the team will also go far beyond the border, with protocols that can be adapted or adopted by other areas dealing with water quality issues.

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