Robotics exec talks plans for new Houston office and the future of automation

robot revolution

Marie Myers is the CFO of UiPath and is based in the company's new Houston office. Courtesy of UiPath

It's safe to say that Marie Myers — CFO of UiPath, which opened its 71-person office in Houston earlier this year — loves her job.

The robotics process automation company, which was founded in Romania before moving its headquarters to New York City last year, is in major growth mode. At the helm of the financial side of things is Myers, who has over 20 years of experience in technology.

When Myers was working on a spinoff project for HP, she started seeing the difference software automation makes on a company's bottom line.

"I realized RPA was the fastest way to drive efficiencies, so I started building bots," she tells InnovationMap. "During that time, I came across UiPath and I saw how impressive their technology was. In my more than two-decade career, I hadn't really come across a technology that I felt that had such an impressive impact in such a short time."

She drank the UiPath Kool-Aid, and when the company came to her adopted hometown of Houston to open an office to be its central, Midwestern location, she leapt at the opportunity to join the team. Now, with several months under her belt in the position and a growing office, Myers speaks with InnovationMap about the company's growth and the revolution that RPA is having in business.

InnovationMap: You've been in your role since January, but you've been in tech for a while now. How has the transition been for you?

Marie Myers: This has been one of the most exciting times for my career. I've been in tech for about two decades. I started with Compaq — quite an incredible company that started right here in Texas. It was a very famous startup in its own time, and I had a chance to be a part of that wave, which was really incredible. Then, it got bought out by HP, and then I pivoted and spent a lot of time in Silicon Valley for a couple decades.

I got involved in robotics process automation quite by happenstance about four years ago when HP decided to split. I was involved in setting up a company from the finance and legal perspective. I got challenged to drive some cost efficiency, so I turned to RPA as a means to drive some of that impact within my own organization of a couple thousand folks.

When the opportunity came up to be CFO for UiPath, I really jumped at it because it filled two important things for me. I wanted to be a leader of a finance organization and team. Secondly, I wanted to do something where I was really passionate about the technology. When I think about RPA, the world lights up for me. It's truly transformative.

IM: How did UiPath decide to open a Houston office? What made the city a key market?

MM: Houston — particularly Texas — are both important for us, from a customer perspective. We have some of our larger companies in the country here in Texas, so it was a natural place to look to build capability. Secondly, we're impressed with the overall quality of the market and the availability of different skills here as we build out our company.

IM: What are some goals UiPath has for its new Houston office?

MM: Overall, one of the key goals is to establish a strong Midwest presence for the company. Texas is an ideal location if you think about it for customers that range from the East to the West. Being in the middle is a good, central location. Also, as we grow and expand in Latin America, it's another interesting spot for us. So, one, to ensure that we are able to support the growth needs of the company throughout the United States and leverage the strategic location that Texas has.

I think the other goal is to build some of the core skills we need for the overall organization as we grow in the United States. UiPath is a relatively new player in the U.S., only been here a couple of years.

Finally, we've got terrific customers here, so what's important is to continue to support and nurture those customers. We have a big presence in oil and gas and the support companies within energy.

IM: Tell me about the Academic Alliance and how the company engages with students.

MM: Basically, we offer free training to the universities so that students can get first-hand experience for robotics process automation, which is part of our broader commitment we've made to ensure RBA is available in an open, democratized way.

We are big proponents of supporting students, and we had a great intern program this last summer. We had a double-digit number of interns — I think the largest population in the U.S. We love the fact that we have this access to universities that we can easily tap into.

Just a couple weeks ago we ran UiPath's first-ever hackathon for students in the United States. We had over 50 participants.

We're really excited about building out the ecosystem with the universities and the students here in Houston.

IM: What sort of misconceptions do you encounter within automation?

MM: First and foremost, a lot of it is misconceptions about RPA replacing jobs. I'd say it's a shift in the workforce — I witness this first hand because I had a team where we implemented and built bots. What happens is you create capacity and end up creating new jobs. You have roles of managing bots, bot controllers, bot librarians — these are roles that fundamentally didn't exist five years ago.

IM: What advice do you have for women in tech?

MM: I think it's so critical for women to be in the driving seat and in the forefront of technology. I have two daughters and I'm adamant about how they are exposed to robotics. I did a coffee talk in Houston not too long ago, and I really challenged the women to get out there and get digitally literate. It's really important as women that we don't let ourselves fall behind on technology and how they are impacting both our work and our families. So, staying informed, no matter how you do that — reading, podcasts, news. Another way is to join and network with associations. Myself and another woman important in this space are looking to create a network for women in automation. We want to build a group that will allow women to look for jobs, board roles, mentors, etc. in this industry.

IM: What role do you see Houston playing in the greater innovation conversation and where does the city have room to improve?

​MM: I'm a big fan of Houston. I'm Australian, but I feel like a Texas implant now. It's an incredibly diverse city, and I think that's one of its greatest strengths. You've got people from all walks of life from all parts of the world and a great education system. That creates a really unique backdrop for the technology-led era we're in. The historical strengths of the city have been predicated on the healthy oil and gas sector and medical sector — both are important industries going through major technology transformations. I think for Houston being able to capitalize on all that is a very unique opportunity. It will position Houston very well for the future. You've got the right ingredients here.

Where the city is going to have to continue to build is specifically around some of these skills for the future. Artificial intelligence and having that depth of experience is an area the city struggles in. Certainly other cities like Seattle and San Francisco have tens of years of experience from companies like Google, Facebook, and Amazon that have been able to build deep AI. In Houston, that skillset is going to come more from oil and gas, where they've been building some of those skills, just not in the same breath and not in the same depth as those other cities. I think the real opportunity is to nourish and nurture this in the academic institutions and then take that talent out of the academic institutions and integrate them into the corporations.

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Portions of this interview have been edited.

UiPath's Houston office is in a historic downtown Houston building that's been renovated. Courtesy of Main&Co

Global automation company doubles down on Houston as it grows its United States presence

New bot on the block

When UiPath decided to look into an office in Houston, it was a bit of a gamble, since Houston's not particularly known for its wealth of hardware talent.

"We did a little bit of an experiment to see what the skills would be like specifically in a Houston office," Marie Myers, CFO of the company and based in Houston, tells InnovationMap. "As a robotics company, we weren't sure if we'd get more of those software skills. It's not a natural market for those skills."

But Houston — and Texas in general — is a great location for the robotics process automation company, Myers says. It's central and optimal for customer acquisition. Valued at $7 billion, UiPath has over 2,500 customers — adding six more a day on average, according to a news release.

Since beginning Houston operations in January, Myers says she's very pleased with the 71-person team the company has assembled locally, and the company has even expanded in that short time. Following a $568 million Series D round closing, the company almost doubled its office size.

"The Series D is critical for us as we continue to grow and we're using those proceeds to grow our base across the world, and obviously part of the Houston expansion has been just that," Myers says.

UiPath plans to really settle into Houston and even bring a an RPA Immersion Lab into its Houston office. The lab would allow for potential customers to try out the technology and run simulations. The lab is on the docket for 2020, Myers says.

Another way UiPath is engaging with the Houston community is through its connection to students and universities. The company has an arrangement with six universities in Houston and is even located just across the street from the University of Houston-Downtown. Myers says the company had one of its largest group of interns working in Houston.

"It's going to be so important for students graduating to have experience in up-and-coming technologies, like RPA," Meyers says. "We see such great support from the local universities."

Main&Co's office space is now 100 percent leased. Courtesy of Main&Co

Recently renovated Downtown Houston office space snags leases from 2 tech companies

Tech Space

Two tech-focused companies moved into a newly developed office space in downtown Houston at the intersection of Main Street and Commerce Street. One company relocated its Houston office, and the other company has expanded to the city for the first time.

Oil and gas AI-enabled analytics platform, Ruths.ai relocated its downtown office to Main&Co, located at 114 Main St. The company has 8,457 square feet of office space in the recently renovated historic building.

Meanwhile, global robotics process automation company UiPath has expanded to build a Houston team. The computer software company is based in New York, but has a presence in 18 countries. The company's office has 5,187 square feet of Main&Co's office space.

The two leases account for 100 percent of the office space in the mixed-use facility, which is owned by Houston-based investment firm, NewForm Real Estate. The company does have 1,136 square foot street-level retail space left yet to rent.

The five-story development completed renovations in the summer of last year and has, in addition to the office space, bars — including The Cottonmouth Club, ETRO Nightclub and Lilly&Bloom — and a contemporary art gallery on the fifth floor called the LCD Gallery.

"Main&Co has become a bustling epicenter of culture, arts, nightlife, and commerce in Downtown Houston," says Dan Zimmerman, president of NewForm Real Estate, in a release. "Restoring these iconic historic buildings and leasing the office space to cutting-edge tech firms is a testament that landmark real estate has a place in the future landscape of our city."

Last week, Greenway Plaza announced three different tech organizations that are moving to or had moved to its office park. Those transactions accounted for over 20,000 square feet of space.

Recently renovated

Courtesy of Main&Co

The renovation of the structure concluded in June of 2018.


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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

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