Know before you go: 2024 H-Town Roundup

Plan your week

Here's what you need to know about HTR this year. Photo courtesy

Next week, Houston Exponential's annual week of innovation and networking is taking place. Here are five things you need to know before you go.

1. New year, new name.

Houston Tech Rodeo, which originated in 2020, has been rebranded to H-Town Roundup, but the week of innovation and entrepreneurship still has the same goal of providing programming and events that connect and educate Houstonians.

On a recent episode of the Houston Innovators Podcast, Natara Branch, CEO of Houston Exponential, says the change is meant to make for a more inclusive experience for entrepreneurs of small businesses, something she's seen a need for since she took on her role last year.

"This year, we've had the better part of a year to think about what can be different and how can we serve the founder," she says.

Branch explains that some members of the Houston community confused the event for being associated with the Houston Livestock Show and Rodeo or for being only for true tech people. Branch says the wanted to open the door a little wider to entrepreneurs who are innovative without necessarily working in technology.

"That's not what we wanted — to exclude anyone," she says. "H-Town Roundup is going to allow us to be more inclusive."

2. It's completely free to attend.

Dozens of events are taking place around town, and all are free to Houston entrepreneurs, investors, and more. Simply register for anything you're able to attend.

For reference, a full, detailed agenda is available online too.

3. There are two featured events.

Need to make some priorities? This year, there are two featured events for HTR.

  • Tech and Tequila Talk powered by Blue People at 5 to 7:30 pm, on Tuesday, February 27, at the UH Tech Bridge Innovation Center.
  • CodeLaunch Houston at 4 to 9 pm, on Wednesday, February 28, at Bayou Music Center.

4. Introducing: The Founder Lounge.

For attendees with the founder pass, The Founder's Lounge at Esperson Building in downtown is open Monday through Thursday from 10 am to 3 pm next week.

The full agenda of talks planned at the lounge is online.

5. Find the activity zones.

HTR again is rotating venues. Here's where and when you can expect to find HTR activities.

  • Sunday (1 to 5 pm) - Esperson Building
  • Monday (8 am to 12:30 pm) - TMC Innovation
  • Monday (1:30 to 5 pm) - The Cannon Downtown
  • Tuesday (1 to 7:30 pm) - UH Tech Bridge
  • Wednesday (10 am to 1 pm) - Esperson Building
  • Wednesday (4 to 9 pm) - Bayou Music Center
  • Thursday ( 8 am to noon) - HCC Central Campus
  • Thursday (1 to 7 pm) - Greentown Labs
  • Friday (9 am to 3:30 pm) - the Ion
  • Saturday (10 am to 2 pm) - Esperson Building

A new program launched by two UH-based organizations will help early-stage startups commercialize, apply for grants, and more. Photo via UH.edu

University of Houston launches new collaborative program for startups in Houston, Gulf Coast Region

ready to grow

Two University of Houston organizations have partnered up to further support early-stage startups in the Gulf Coast Region.

The university announced this month that its UH Technology Bridge and the UH Texas Gulf Coast Small Business Development Center are now accepting applications for a new, collaborative program that will help innovators and entrepreneurs develop a pitch or commercialization plan. The program will also guide participants in applying for Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants and other investments.

Applications are open to those with the university and across the region.

"We are excited to partner with the University of Houston Technology Bridge to provide this valuable support to early-tech startups in the Texas Gulf Coast region," Steven Lawrence, director of the UH Texas Gulf Coast SBDC Network, says in a statement. "Our program is designed to help innovators take their ideas to the next level and prepare for success in the marketplace."

"Our goal is to help innovators turn their ideas into successful businesses, and this partnership will help us achieve that goal," Tanu Chatterji, Associate Director of Startup Development at UH, echoes in the news release.

The UH Texas Gulf Coast SBDC Network is one of 14 SBDCs in the Texas Gulf Coast Region that's part of UH's C.T. Bauer College of Business and funded in part by the U.S. Small Business Administration. The centers provide no-cost and affordable business training and advising.

The UH Tech Bridge focuses on providing research and development space to UH-affiliated startups and entrepreneurs. The 15-building complex and its 31,000 square feet of incubator space houses more than 20 small companies and startups that provide internship and learning opportunities for UH students, along with several federally funded research centers and institutes.

Earlier this year, the Tech Bridge received a $2.875 million grant from the U.S. Department of Housing and Urban Development. The grant is slated to benefit the UH Industry & International Innovation Hub and will establish The Deck Innovation & Coworking Center.

Ramanan Krishnamoorti, the vice president of energy and innovation at the University of Houston who oversees the UH Technology Bridge, spoke with the Houston Innovators Podcast earlier this summer about UH's plans to build a central campus hub for innovation and the need to encourage more innovation and entrepreneurship.
TexPower's founders — Board Chairman Arumugam Manthiram, CTO Wangda Li, and CEO Evan Erickson, respectively — celebrated the opening of the company's new lab space. Photo courtesy of TexPower

Houston startup with revolutionary battery technology opens new labs

power move

A Houston startup founded off research out of a Texas university has cut the ribbon on its new lab space.

TexPower EV Technologies Inc. celebrated the opening of its 6,000-square-foot laboratory and three-ton-per-year pilot production line at a ribbon-cutting event last week. The Northwest Houston site is located at 6935 Brittmoore Rd.

The new space will help the company further commercialize its cobalt-free lithium-ion cathode, lithium nickel manganese aluminum oxide (NMA). The technology is game changing for the electrification of the United States, including the rapid adoption of electric vehicles.

Currently, the country is experiencing a supply chain crisis, says Evan Erickson, co-founder and CEO of the company, at the event. Most of the world's cobalt, a material traditionally used in lithium-ion cathodes, is sourced primarily from the Congo and refinement is mostly controlled by China, he explains.

For these reasons, Cathodes are the most expensive component of lithium-ion batteries. But TexPower has a unique technology to solve this supply chain issue, and now with its new labs, is one step closer to commercialization of its materials.

TexPower spun out of the University of Texas at Austin in 2019. The company was co-founded by Erickson with CTO Wangda Li and Board Chairman Arumugam Manthiram, a professor at UT whose lithium-ion battery research fuels the foundation of the company.

“We want to point out how lucky we are — as a company and as scientists," Erickson says at the ribbon cutting event. "It’s not common that you see something you work on in academia turn into something that can become commercially successful.”

Prior to the newly built labs, TexPower operated out of the University of Houston's Tech Bridge. The company intends to raise additional funding to support its expansion.

According to the company, the new three-ton-per-year pilot line is the first step toward building a manufacturing facility that's capable of producing up to 50 times more the amount of cathode with a goal to impact markets such as defense, power tools, and eVTOL.

CEO Evan Erickson celebrated the new lab space opening last week

Photo courtesy of TexPower

UH is investing in a nanotechnology developed on its own campus that can help prevent the spread of COVID-19. Photo courtesy of University of Houston

University of Houston to install nanotech-coated air filters on campus to prevent COVID-19 spread

who's house

A nanotechnology developed at the University of Houston is about to make a big difference right on campus.

UH's Facilities/Construction Management Preventive Maintenance team is working on a project that will install air filters that are nanocoated with a material that was first developed at the UH Technology Bridge. UH Professor of Physics Seamus Curran has an extensive background in nanotech, and, as he learned more about COVID-19 and how it spreads, he started nano-coating facemasks to make them more resistant to the small particles that enable the spread of the virus.

Originally developed for the construction business, Curran's coating material could also be used to create hydrophobic facemasks, Curran discovered, and he founded a spin off company, Curran Biotech, to develop his next pandemic-proof innovation: nano-coated air filters.

"The big thing for me when we were shut down was that people couldn't go to work or school. The country can't live that way — but you can't send people back to work in a world that's not safe," Curran said last October in an interview for the Houston Innovators Podcast. "How do you create a safer environment? That's the thing that really got me going in the beginning in the summer. We looked at filters."

Listen to Professor Curran on the Houston Innovators Podcast:

Curran, who says he's learned more about air filters than he ever cared to, realized that even the most expensive air filters can only protect from 10 to 25 percent of viruses. And most buildings' HVAC systems would have to be replaced completely to allow for these pricier, more protective filters. But Curran Biotech's Capture Coating can be used on existing filters and HVAC systems.

Air filters coated with Curran Biotech's sealant were then tested at the New York Family Court Building, by DCAS-Energy Management Division, and now, ahead of the fall semester, UH is implementing the innovation in all buildings that have less than MERV-13 rated filters.

Curran Biotech's sealant can be used on existing air filters and HVAC systems. Photo via UH.edu

Think you know what's happening at university tech transfer offices? Think again. Graphic by Miguel Tovar/University of Houston

Houston expert: 4 misconceptions of university tech transfer offices

houston voices

Beyond their education and research missions, universities across the nation have turned research discoveries into big business. In addition to protecting intellectual property from faculty discoveries, universities build and support startup pipelines to help researchers commercialize those technologies.

However, there are a few misconceptions when it comes to university tech transfer offices that keep faculty at bay. Here, we'll take a look at four misconceptions and explore the truth behind the thinking.

Misconception 1: Filing patent paperwork is all tech transfer offices do

While tech transfer offices are in the business of patents, many offer a full range of services to support the commercialization process. This can include everything from strategy and startup development to the establishment of enterprise and industry ventures. Many university tech transfer offices operate incubators, co-working space for startups and accelerator programs, and some even build and manage venture funds.

"At the University of Houston, we now offer lots of services to faculty, such as strategy sessions to help them understand the commercial potential of their technologies," said Chris Taylor, executive director of the UH Office of Technology Transfer and Innovation. "We also help faculty license their technologies to ensure fair use as they transition them into the market."

Misconception 2: I need to have a fully-developed idea to submit a disclosure

According to Taylor, many faculty begin interacting with tech transfer offices once they have a technology fully developed. But tech transfer offices can do much more for faculty if involved early in the process.

"Yes, we do help protect what's been developed. But, if we have a conversation at the beginning, we could help faculty shape or pivot their technologies. This will give them the greatest market potential," he said.

One of the many benefits of tech transfer offices is their ability to readily research the market.

"We can determine whether or not technologies can be disclosed, patented and licensed. It's important to know this before going through a lengthy and expensive filing process."

Misconception 3: The patent process will slow down my publication plans

Publishing researching findings may be one of the most important activities for the university researcher. However, publishing research on unprotected discoveries can result in the loss of patent rights. Therefore, filing a disclosure is very important, according to Taylor.

"Publishing is one of the best ways to market university technologies," he said. "However, industry values patented technologies, so it's better to make a small time investment to protect your IP.

Misconception 4: Getting a patent is the primary goal for tech transfer offices

As Taylor explains, the primary goal of tech transfer offices is to help faculty "transfer" their discoveries to society. And while patenting technologies is one way to do that, tech transfer offices also provide education and mentoring programs. They also support other protections such as copyrights for software.

"IP protection is important," he said. "It gives faculty control over how their technology is used, for good or for bad. So, this is an important part of the work that we do for faculty. But, we support faculty in so many other ways through the entire pipeline."

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This article originally appeared on the University of Houston's The Big Idea. Lindsay Lewis, the author of this piece, is the executive director of communivations for the UH Division of Research.

Contact-free market shopping has come to campus at UH. Photo courtesy of UH

University of Houston upgrades to contactless market technology

new to campus

A convenience store on campus at the University of Houston just got a little more, well, convenient — and a whole lot safer.

UH and its dining services partner, Chartwells Higher Education, have partnered with tech company Standard to upgrade the check-out process of convenience shopping. The technology is easy to install and can retrofit any convenience store to a contact-less process.

"Students' tastes change constantly, and we're well equipped to handle that. But their shopping preferences evolve too, and we want to continue providing new and unique shopping experiences that are unexpected on a college campus," says David Riddle, vice president of operations for Chartwells Higher Ed, and district manager for UH System Dining, in a press release. "This is the future of shopping, and with autonomous checkout through Standard, we've made it as easy, safe and convenient as possible for students to come in, get what they need, and go."

The store, called Market Next, is located at UH's Technology Bridge and opened earlier this month. Enabled by cameras and easy-to-use scanners, the store operates 24 hours a day and is also designed for quick service for students on the go. The fastest shopping trip recorded by Standard is 2.3 seconds.

"Market Next is the first retail store in the world to be retrofitted for a 100 percent cashierless, checkout-free experience," says Jordan Fisher, co-founder and CEO of Standard, in the release. "Our platform is the only system on the market proven to retrofit an entire retail experience. Innovative retailers like Chartwells use the AI-powered Standard platform to enable shoppers to grab any product they want and simply walk out, without waiting in line. We are excited to partner with Chartwells to deliver this groundbreaking technology to more locations around the country."

Chartwells is working with Standard to bring more of these stores across the country — as well as more itterations on the UH campus.

"Checkout-free technology is an innovation that will make our students' lives a little easier and a lot safer. This is the new standard for campus safety that is important to students today and for the foreseeable future," says Emily Messa, associate vice chancellor and associate vice president for administration at UH, in the release. "That's why we will plan to convert additional Market stores on campus to this technology in the coming year."

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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