University of Houston looks at how to navigate which ongoing research is considered essential

Houston voices

Is all research essential? Nope. Miguel Tovar/University of Houston

Many researchers have begun to work from home due to the novel COVID-19 pandemic, and only essential personnel are allowed to work on university campuses. For a researcher, what is considered "essential personnel"? Isn't all research essential to the workings of a public research university?

In a word, no.

As much as one would like to believe their respective job is of the utmost importance to human existence, certain mitigating factors can overrule that sensibility – and the definition of the word "essential" – in a moment's time. According to an article in Inside Higher Education, a Ph.D. candidate researching diabetes at the University of Toronto said, "There is no single experiment or laboratory activity that is more important than saving the life of even a single individual in the community."

Your university or institution may not have closed completely, yet it is safe to suspect that you have been asked to complete most of your work remotely. With most counties in the nation declaring a shelter in place order, researchers who have been required to "ramp down" lab activities may be feeling extreme disappointment and even panic.

Allowances and exceptions for federally funded research

The NSF has extended deadlines for some applications and reports. For instance, it has extended the dates of all annual project reports due between March 1 and April 30 by 30 days. In addition, the charge of costs or fees that have been incurred due to COVID-19 can be negotiated, as long as there is proper documentation and the result is not a shortage of funds to eventually carry out the project.

The NIH released NOT-OD-20-086 on March 12, 2020 to alert the research community of certain flexibilities which apply to NIH applicants and recipients. Some of these include pre-award costs, extension of required reporting, prior approval waivers and expenditure of award funds – especially involving travel. There are other exceptions being made, including allowing salaries to be charged against grant monies in some instances.

So, you have to go to campus

If you are a researcher who ensures the continuity of key operations, such as an animal care operations worker, there are several things you can do to keep yourself and your colleagues safe, which will come as no

surprise:

Very few researchers are allowed on campus. If you are working on campus, keep 6 feet away from your co-workers. There should be a greatly reduced number of researchers in the lab or facility at any given time.
Wash your hands. Follow all environmental safety and hazardous material rules to a tee.
Be careful when getting deliveries and regularly clean your workspace.
Research the many funding opportunities that are available to contribute to the solution of COVID-19 related issues.

Just breathe…it’s going to be okay

If this pandemic has taught us anything, it is that an emergency plan is the best bet for staving off panic and flowing as seamlessly as possible into a remote working situation. As always, safety is goal one and this situation's trajectory is causing safety concerns to escalate. Your research will ramp up again, make no mistake, although for the time being it may have fallen victim to this outbreak. If you stay in close adherence to policies put forth by your institution and you keep your sponsor abreast of your next steps, all will work out in the end.

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This article originally appeared on the University of Houston's The Big Idea.

Sarah Hill is the communications manager for the UH Division of Research.

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Houston health care leader secures funding, milestones for latest initiatives across cancer, stroke, and more

news roundup

UTHealth Houston is making waves in many disciplines right now. From cancer to Alzheimer’s disease to stroke, the institution is improving outcomes for patients in new ways. Last week, UTHealth announced three exciting updates to its roster of accomplishments.

On October 8, UTHealth announced that it had received a $4.8 million grant from the National Cancer Institute, aimed at helping cancer survivors to continue their healing and enhancing primary care capacity. It will be put into action by UTHealth researchers working with eight community health centers around Texas that treat un- and underinsured patients. The initiative is called Project CASCADE, which stands for Community and Academic Synergy for Cancer Survivorship Care Delivery Enhancement.

“Project CASCADE focuses on how primary healthcare teams provide whole-person and coordinated care to underserved patients who have a history of cancer,” says Bijal Balasubramanian, professor of epidemiology and the Rockwell Distinguished Chair in Society and Health at UTHealth Houston School of Public Health, a multiple principal investigator of the study. “Primary care is uniquely suited to deliver whole-person and coordinated care for cancer survivors because, at its core, it prioritizes, personalizes and integrates healthcare for all conditions, not just the cancer.”

He continued by adding that 70 percent of cancer survivors live with other chronic conditions. The study will help by taking a holistic approach, rather than relegating people’s care to many different teams. Project CASCADE is one of only four National Cancer Institute-funded U01 grants that have been awarded to applicants focused on primary care for cancer survivors.

“Community health centers are the primary-care homes for patients who are underinsured or uninsured. In collaboration with community health center clinics, this study will develop a model of cancer survivorship care that can be disseminated and scaled up to be used across other health systems in Texas,” Balasubramanian says.

The intervention will use a designated care coordinator champion to oversee every aspect of patients’ health journey. Project ECHO will provide a backbone for treatment. That’s a telementoring strategy that improves primary care clinicians’ knowledge about post-cancer care, recognition and management of the effects of cancer and its treatments, and communication between oncologists and the primary care team. Project CASCADE is also a partnership between The University of Texas System institutions, including UT Southwestern Medical Center and The University of Texas MD Anderson Cancer Center.

The previous week, UTHealth made history by performing the first infusion in Houston of a newly FDA-approved drug, Kisunla, for the treatment of early symptomatic Alzheimer’s disease. The lucky recipient was 79-year-old Terrie Frankel. Though Kisunla is not a cure for Alzheimer’s, it has been noted to slow progress when administered early in the disease’s encroachment.

“Mrs. Frankel is the ideal patient for this treatment,” her doctor, David Hunter says. “We want to see patients as soon as they, or their family, notice the slightest trace of forgetfulness. The earlier the patient is in their Alzheimer’s disease, the more they benefit from treatments like Kisunla.”

UTHealth was one of the sites in the trial that charted the fact that Kisunla reduced amyloid plaques on average by 84 percent at 10 months after infusion. Frankel will receive her infusions monthly for the next 18 months, and her doctors will keep tabs on her progress with PET scans and use MRIs to scan for possible side effects. Next year, researchers will begin recruiting participants over the age of 55 with a family history of dementia, but no memory loss themselves, for a new trial, one of several currently working against Alzheimer’s that are taking place at UTHealth.

Stroke is no less of a worry to many patients. Last week, UTHealth received another grant that will improve the odds for patients who have had a stroke with the successful re-opening of a blocked vessel through endovascular surgery. The $2.5 million grant from the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, will fund a five-year study that will include the creation of a machine-learning program that will be able to predict which stroke patients with large blood vessel blockages will benefit most from endovascular therapy.

The investigators will form a database of imaging and outcomes of patients whose blockages were successfully opened, called reperfusion, from three U.S. hospitals. This will allow them to identify clinical and imaging-based predictors of damage in the brain after reperfusion. From there, the deep-learning model will help clinicians to know which patients might go against the tenet that the sooner you treat a patient, the better.

“This is shaking our core of deciding who we treat, and when, and how, but also, how we are evaluating them? Our current methods of determining benefit with imaging are not good enough,” says principal investigator and associate professor in the Department of Neurology at McGovern Medical School at UTHealth Houston, Sunil Sheth.

And this is just some of the groundbreaking work taking place at UTHealth each day.

Houston plugs in as 3rd cheapest city in America for remote workers

report

Houston's bustling telework industry is earning a new reputation as one of the most affordable in the country. A recent study by online retailer The Perfect Rug has revealed Houston is the No. 3 cheapest U.S. city center for remote work.

The report ranked the top 10 largest U.S. cities based on population data, the number of coworking spaces and cafes per capita, statewide average internet speeds, average apartment rent prices, and more.

Houston falls third to the far west Texas city of El Paso (No. 1), and Austin (No. 2).

When it comes to finding the best place to work remotely, Houston has an abundance of options including coffee shops, coworking spaces, and local library branches. According to the report's data, there are about six coworking spaces and 16 cafes per capita in the city, but Houstonians know best that there is a much wider variety of places to work from "home" than whatever number a study determines.

The average internet speed in Texas is 425.9 mbps (megabits per second), which is the fourth-highest internet speed out of the six total states (and the District of Columbia) mentioned in the study. Pennsylvania, Washington, and Washington, D.C. all have faster average internet speeds, at 430.8, 451, and 473.8 mpbs, respectively.

The Perfect Rug also calculated the average costs for meals, coffee, and monthly rent in Houston:

$1,196 per month – Average apartment rent cost in central Houston
$15 per hour – Average cost for a desk at a coworking space
$18 – Average cost for a meal
$5.32 – Average cost for a coffee

Furthermore, Houston-based remote workers are technically saving on fuel costs compared to those who have to commute into the city daily for their jobs.A spokesperson for The Perfect Rug said Texas cities like El Paso, Austin, and Houston are far more popular for "budget-conscious" remote workers partially because rent costs are far lower in comparison to many other U.S. cities.

"On the other hand, cities like Washington, D.C., and Seattle, while more expensive, compensate with faster internet speeds and a higher density of workspaces, which can enhance the remote work experience," the spokesperson said. "Finding the right balance between cost and amenities is key for remote workers seeking both productivity and affordability."

Elsewhere in Texas, San Antonio ranked as the fifth most affordable city for teleworkers, followed by Dallas (No. 7).

The top 10 cheapest U.S. cities for remote workers are:

No. 1 – El Paso, Texas
No. 2 – Austin, Texas
No. 3 – Houston, Texas
No. 4 – Seattle, Washington
No. 5 – San Antonio, Texas
No. 6 – Washington, D.C.
No. 7 – Dallas, Texas
No. 8 – Denver, Colorado
No. 9 – Philadelphia, Pennsylvania
No. 10 – Nashville, Tennessee

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This article originally ran on CultureMap.

SpaceX reaches milestone achievement with latest Starship rocket launch

science nonfiction

Texas-based SpaceX pulled off the boldest test flight yet of its enormous Starship rocket on Sunday, catching the returning booster back at the launch pad with mechanical arms.

A jubilant Elon Musk called it “science fiction without the fiction part.”

Towering almost 400 feet (121 meters), the empty Starship blasted off at sunrise from the southern tip of Texas near the Mexican border. It arced over the Gulf of Mexico like the four Starships before it that ended up being destroyed, either soon after liftoff or while ditching into the sea. The previous one in June had been the most successful until Sunday's demo, completing its flight without exploding.

This time, Musk, SpaceX's CEO and founder, upped the challenge for the rocket that he plans to use to send people back to the moon and on to Mars.

At the flight director's command, the first-stage booster flew back to the launch pad where it had blasted off seven minutes earlier. The launch tower's monstrous metal arms, dubbed chopsticks, caught the descending 232-foot (71-meter) stainless steel booster and gripped it tightly, dangling it well above the ground.

“The tower has caught the rocket!!” Musk announced via X. “Big step towards making life multiplanetary was made today.”

Company employees screamed in joy, jumping and pumping their fists into the air. NASA joined in the celebration, with Administrator Bill Nelson sending congratulations.

Continued testing of Starship will prepare the nation for landing astronauts at the moon’s south pole, Nelson noted. NASA’s new Artemis program is the follow-up to Apollo, which put 12 men on the moon more than a half-century ago.

“Folks, this is a day for the engineering history books,” SpaceX engineering manager Kate Tice said from SpaceX headquarters in Hawthorne, California.

“Even in this day and age, what we just saw is magic,” added company spokesman Dan Huot from near the launch and landing site. “I am shaking right now.”

It was up to the flight director to decide, in real time with a manual control, whether to attempt the landing. SpaceX said both the booster and launch tower had to be in good, stable condition. Otherwise, it was going to end up in the gulf like the previous ones. Everything was judged to be ready for the catch.

The retro-looking spacecraft launched by the booster continued around the world, soaring more than 130 miles (212 kilometers) high. An hour after liftoff, it made a controlled landing in the Indian Ocean, adding to the day's achievement. Cameras on a nearby buoy showed flames shooting up from the water as the spacecraft impacted precisely at the targeted spot and sank, as planned.

“What a day,” Huot said. “Let's get ready for the next one.”

The June flight came up short at the end after pieces came off. SpaceX upgraded the software and reworked the heat shield, improving the thermal tiles.

SpaceX has been recovering the first-stage boosters of its smaller Falcon 9 rockets for nine years, after delivering satellites and crews to orbit from Florida or California. But they land on floating ocean platforms or on concrete slabs several miles from their launch pads — not on them.

Recycling Falcon boosters has sped up the launch rate and saved SpaceX millions. Musk intends to do the same for Starship, the biggest and most powerful rocket ever built with 33 methane-fuel engines on the booster alone.

Musk said the captured Starship booster looked to be in good shape, with just a little warping of some of the outer engines from all the heat and aerodynamic forces. That can be fixed easily, he noted.

NASA has ordered two Starships to land astronauts on the moon later this decade. SpaceX intends to use Starship to send people and supplies to the moon and, eventually Mars.

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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.

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