A concept design rendering of Persona AI's humanoid robot. The company is expanding at the Ion and plans to deliver prototype humanoids by the end of 2026 for complex shipyard welding tasks. Rendering courtesy Persona AI.

Houston-based Persona AI announced the expansion of its operations at the Ion and a major milestone in deploying its humanoid robots.

The company will establish a state-of-the-art development center in the prominent corner suite on the first floor of the Ion, and is slated to begin expansion in June.

“We chose the Ion because it’s more than just a building — it’s a thriving innovation ecosystem,” CEO Nicolaus Radford said in a news release. “This is where Houston’s tech future is being built. It’s a convergence point for the people, energy, and ideas that power our mission to redefine human-machine collaboration. For an industrial, AI-driven robotics company, there’s no better place to scale than in the heart of Houston.”

Persona AI’s new development center will be located in the suite utilized by the Ion Prototyping Lab, managed by TXRX Labs. The IPL will transition its operations to the expanded TXRX facility in the East End Maker Hub, which will allow the lab to grow its team and meet increased demand.

At the start of the year, Persona AI closed $25 million in pre-seed funding. Earlier this month, the company announced a memorandum of understanding with HD Korea Shipbuilding & Offshore Engineering, HD Hyundai Robotic, and Korean manufacturing firm Vazil Company to create and deploy humanoid robots for complex welding tasks in shipyards.

The project will deliver prototype humanoids by the end of 2026, with field testing and full commercial deployment scheduled to begin in 2027.

"As heavy industry faces growing labor constraints—especially in high-risk trades like welding—the need for rugged, autonomous humanoid robots is more urgent than ever,” Radford added in a separate statement. “This partnership with HD Hyundai and Vazil is more than symbolic—deploying to the shipyard is one of the largest real-world proving grounds for Persona's tough, humanoid robots.”

The East End Maker Hub, a public-private endeavor, aims to put Houston on the map for manufacturing. Photo by Natalie Harms

Photos: $38M innovative maker hub space opens in Houston's East End

new to hou

A new 300,000-square-foot innovation and manufacturing hub with a goal of creating 1,000 new companies in the next five years has officially celebrated its grand opening.

The East End Maker Hub — a $38 million public-private partnership — is anchored by TX/RX Labs, a makerspace nonprofit, and located at 6501 Navigation Blvd. So far, 25 companies have signed leasing agreements with the hub that has two of its three phases completed.

"Houston can become the next great manufacturing hub in America," says Roland von Kurnatowski, president at TX/RX Labs. "We can decrease our external reliance and increase our resilience."

The grand opening event, which was held June 3, was attended by makers, EEMH tenants and employees, and some of the local politicians that aided in making the hub a reality with grants, private funding, and more.

The EEMH has officially celebrated its grand opening. Photo by Natalie Harms

"We've always been a city of amazing innovation, whether it's been in energy, medicine, or space exploration," says Mayor Sylvester Turner. "And, we've led the world in whatever we have chosen as the pursuit of our endeavors. One thing about this city is that when we work together, we win."

"The East End Maker Hub provides an opportunity to reclaim our history of innovation and manufacturing and to ensure that the process of innovation is equitable," Turner continues. "It is not saying much to be diverse if you are not inclusive at the same time."

Through TX/RX and other tenants, the EEMH will aim to provide education, workforce development, jobs, and entrepreneurial space to innovators, students, and more.

The mission of the East End Maker Hub is to "drive advanced manufacturing by bringing together the brightest engineers, scientists, manufacturers, and makers to generate innovative advanced manufacturing solutions," according to Patrick Ezzell, president of the Urban Partnerships Community Development Corporation.

Six Houston startups recently announced their moves into the space, and the EEMH tenants represent everything from 3-D printing and unmanned aerial vehicles to vodka distilling and fragrance design.

Take a slideshow tour of the TXRX space below.

TX/RX Labs is the EEMH anchor tenant

Photo by Natalie Harms


Volumetric Biotechnologies has announced its moving its HQ to the East End Maker Hub. Image courtesy of East End Maker Hub

3D-printing startup to move into rising Houston innovation and maker hub

moving around Hou

The East End Maker Hub has landed perhaps its most intriguing tenant thus far — a Houston startup that makes 3D-printed human organs.

Volumetric Biotechnologies Inc. has leased 11,200 square feet at the East End Maker Hub to serve as its headquarters and manufacturing center. Jordan Miller, co-founder of Volumetric, says one of the benefits of being located at the hub will be access to a cleanroom operated by Alchemy Industrial, a 3D manufacturer of medical devices. Earlier this year, Houston-based Alchemy leased more than 5,400 square feet at the East End hub.

Volumetric will occupy space in the first phase of the 307,000-square-foot project East End Maker Hub. That phase of the $37 million project is set to open soon. The startup's current 5,000-square-foot headquarters is at 7505 Fannin St., near the Woman's Hospital of Texas and south of the Texas Medical Center.

Miller says Volumetric's new home will help it "maintain and accelerate our already breakneck progress." Volumetric's 12 biological, chemical, mechanical, and electrical engineers focus on producing human organs and tissues like the liver, kidney, pancreas, lung, and heart using a mix of medical-grade plastics and human cells.

"We're straining to scale our company as fast as our team is inventing and progressing our technologies. It's an absolutely wonderful problem to have," Miller says.

Volumetric hopes to commercialize its 3D-printed organs in 2021. Founded in 2018, Volumetric is a privately held spin-out of Rice University's Department of Bioengineering. It has received $1.8 million in funding, according to Crunchbase. Investors include Silicon Valley-based Sand Hill Angels, and the Springfield, Virginia-based Methuselah Foundation and Methuselah Fund.

Local Realtor Mike Pittman, a development associate with Pearland-based project partner Urban Partnerships Community Development Corp., recruited Volumetric to the hub. He says he's also working with a distillery, a coffee roaster, and a medical gown manufacturer on leasing space there.

The first phase of the East End Maker Hub is set to open soon. Image courtesy of East End Maker Hub

Once the East End Maker Hub opens, Houston's East End District will be home to the largest maker hub in Texas and one of the largest such facilities in the U.S. Being built in three phases on a 21-acre site at 6501 Navigation Blvd., the East End Maker Hub aims to create an environment that gives members of the community access to trade skills and career opportunities, and to provide businesses a place for innovation and manufacturing. The hub's second and third phases are on track to be finished in 2021.

The soon-to-open first phase will feature "white box" suites, ranging in size from 420 square feet to 20,000 square feet, that cater to three sectors:

  • Innovation (robotics, 3D printing, and R&D)
  • Crafting (ceramics, fine woodworking, and screen printing)
  • Light fabrication (food production).

Aside from Alchemy, tenants recently lined up for the hub include Houston-based Waste Management Inc., whose R&D team will occupy more than 3,500 square feet, and Houston-based construction technology company Rugged Robotics Inc., which is renting 1,700 square feet.

"We're not the place for software companies, but our innovation area is the place for hardware companies — those that are into drones, robotics, 3D printing," Pittman says.

The project's hardware innovation element could boost Houston's manufacturing economy, he says. A recent analysis by the Smartest Dollar website found that 7.5 percent of the Houston metro area's workforce is employed in manufacturing. From 1999 to 2019, the number of manufacturing jobs in Houston grew by just 1.9 percent.

So far, the nonprofit TXRX Labs makerspace is the hub's largest tenant, having signed a lease for 65,000 square feet in the first phase. TXRX Labs and Urban Partnerships Community Development teamed up to develop the hub. TXRX contributed $1.25 million in equity, and Urban Partnerships Community Development raised $35.75 million in capital.

Houston-based Stewart Builders is the general contractor for the East End Maker Hub, and Houston-based Method Architecture is the architect of record.

Aside from supplying room for businesses and nonprofits to grow, the hub seeks to provide training and jobs for local residents. Pittman says the hub — located within a tax-advantaged Opportunity Zone — encourages its tenants to hire people who live within a three-mile radius.

"You don't have to go and get a Ph.D. in nuclear science for these jobs to be able to attain really good wages for your family," he says.

Phases two and three of the hub are expected in 2021. Image courtesy of East End Maker Hub

TXRX's new East End Space will allow them to provide prototyping and manufacturing services to more innovators. Courtesy of TXRX

Houston nonprofit makerspace seeking donations as it prepares to move into its new home

Calling for cash

With grants and public funds secured, Houston-based TXRX Labs as one last round of fundraising to acquire before it's ready to head full-speed ahead into its new location.

TXRX launched a $85,000 fundraising campaign to help get the organization where it needs to be before it moves into its 60,000-square-foot space in the East End Maker Hub in spring or summer of next year. The organization, along with its sister nonprofit, Urban Partnership Community Development Corp., has been selected by the city of Houston for an $18 million award and by the federal government for a $5 million innovation grant.

"In the last two weeks, we were getting close to finalizing funding for the building and came up short," says Lauren Caldarera, development director at TXRX. "We wanted to reach out to our membership at TXRX and the broader Houston community to help see if people will help support this unique offering for Houston."

In order to receive those grants, TXRX needs to submit design materials — a process that they budget to cost $325,000. (TXRX has already procured $240,000.) An anonymous donor agreed to match donations, and the organization has until the end of May to raise. Anyone can donate online.

TXRX is focused on bringing back Houston's East End as a manufacturing hub. As manufacturing jobs left the second, third, and fifth wards, it's created a need for skilled labor, middle class jobs, says Roland von Kurnatowski, executive director of TXRX.

"We're looking to bring together innovative companies in the physical innovation space into the East End and creating these middle class jobs," says von Kurnatowski. "It's a modern approach to combating economic inequalities instead of providing handouts."

TXRX is already making a dent in their mission with their smaller space. The organization has over 400 members and incubates 20 or so companies. The new space will allow TXRX to incubate almost twice that amount, work with 75 companies who need prototyping and manufacturing services, and grow their classes and educational offerings.

"Having this space is critical as Houston moves forward in creating an innovation ecosystem," Caldarera says. "We need a space for people to develop their physical prototypes, have engineers and other experts to coach and mentor them, and create more startups and innovators here."

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.

Elon Musk's SpaceX is about to make its debut on Wall Street

Money Moves

Elon Musk's rocket company SpaceX will make its debut on Wall Street Friday, June 12, and both institutional and retail investors are expected to gobble up the 555.6 million shares going up for sale at $135 apiece. Musk, already the world's richest man, could become its first trillionaire.

SpaceX is likely to become the biggest IPO ever, with proceeds of around $75 billion. SpaceX hopes to become the first company to send people to Mars. In fact, part of Musk’s future compensation depends on SpaceX eventually establishing a colony of at least 1 million people on the red planet.

Why SpaceX is going public now

In a video conference on Musk's social media platform X, he told JPMorgan CEO Jamie Dimon that people have suggested for the last 10 years that he take SpaceX public. He's doing it now because the company plans to put 100,000 next-generation Starlink satellites into orbit. Deploying AI data centers in space is a “massive new growth base and you need capital for that,” he said.

Going public provides access to the capital that SpaceX needs. But it also exposes it to more scrutiny from shareholders and more regulatory oversight. That includes filing quarterly financial reports, which critics say incentivizes short-term thinking over longer-term planning and creates unnecessary costs for a company. Securities regulators are currently soliciting public comment on a proposal to require public companies to file the financial reports only twice every year.

How the IPO impacts the company

Musk will hold the majority of a special class of shares, giving him control over decisions related to company strategy, finances and personnel. On the latter, because of his ownership of most of these Class B shares, the only person who can fire Musk as CEO is Musk.

The company credits Musk with being the “driving force” behind its growth, innovation and success. But what happens if Musk is no longer in the picture? SpaceX warns that the loss of Musk could disrupt its ability to execute its strategy as well as hurt its “reputation and relationships with customers, partners and other stakeholders.”

The company also warns that finding a replacement with the same skills and experience as Musk would be time-consuming, if not nearly impossible. As Wedbush Securities analyst Dan Ives wrote Wednesday, “At the end of the day Musk is SpaceX and SpaceX is Musk.”

What could make or break SpaceX

Currently in the test phase, the gigantic reusable Starship rocket is key to SpaceX realizing Musk's ambitions. Much of the commercial space business hinges on SpaceX developing Starship’s capability to be fully reusable and hearty enough for a quick turnaround between flights. If that doesn't happen, SpaceX warns that putting data centers and satellites in space will take longer and cost more money, meaning it risks customers bailing on the company.

Analysts say that by pioneering reusable rockets, SpaceX has established a clear lead on competitors such as Blue Origin, led by Amazon founder Jeff Bezos. The Starlink satellite business competes with, among others, AST SpaceMobile – which is relying on a SpaceX rocket to send its latest generation of satellites into orbit next week.

The prospectus filed last week says SpaceX’s biggest potential market is the sale of business-oriented artificial intelligence products designed to transform how people get work done. It’s an opportunity SpaceX predicts would be worth $22.7 trillion if it could somehow dominate rivals like Anthropic, OpenAI and Microsoft in a highly competitive industry. But the prospectus shows no clear path to profitability for the xAI business, which merged with SpaceX earlier this year.

Why Wall Street is paying attention

If the SpaceX IPO is as successful, the stock could quickly join the Nasdaq 100, a widely followed index that tracks the 100 largest non-financial companies in the composite. That's important because some popular funds, such as the $460 billion QQQ exchange-traded fund, mimic the index and will automatically buy whatever is listed in the index.

Nasdaq recently changed its rules to allow select companies to enter the Nasdaq 100 after just 15 trading days.

S&P Dow Jones Indices, on the other hand, is sticking to established and more traditional thresholds that will not allow SpaceX or other companies with gargantuan IPOs faster entry into its S&P 500 index. That means even high-profile companies will still need to wait for their stocks to trade a full 12 months before they can enter the index.

Companies want to be in the S&P 500 in particular because it's arguably the most important index on Wall Street, with trillions of dollars either mimicking it exactly or benchmarked against it. Vanguard's VOO fund that tracks the S&P 500 has roughly $950 billion invested in it, for example.