This week's roundup of Houston innovators includes Dan Purvis of Velentium, Tony Sanchez of OneNexus Environmental, and Kevin Doffing of Energy Capital of the Future. Courtesy photos
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This new Houston startup is tackling the increasingly dangerous problem of methane-emitting inactive oil and gas wells. Photo courtesy of OneNexus

Houston energy exec launches well-plugging fintech company

future of O&G

Long-time Houston energy executive Tony Sanchez has launched a new fintech company that aims to help oil and gas exploration and production operators decommission orphaned wells and cut down on greenhouse gas emissions.

The company, OneNexus Environmental, was formed in partnership with Houston-based private equity firm BlackGold Capital Management LP and offers exploration and production companies "the equivalent of a universal life insurance policy for their oil & gas wells," according to a statement.

Through OneNexus's model, operators will be able to transfer the title of their wells over to OneNexus, thus absolving all Asset Retirement Obligations (AROs) related to decommissioning inactive wells that are known to release dangerous levels of methane. OneNexus will then assume the financial and operation obligations around properly plugging the wells in a safe, reliable, and cost-effective manner.

"The drastic decline in energy demand that arose from the pandemic forced many operators to walk away from their wells," Sanchez said in a statement. "When orphaned wells started multiplying around the world overnight, what was previously the so-called elephant in the oilfield could no longer be ignored."

Tony Sanchez has founded OneNexus in Houston. Photo courtesy

In addition to the fintech operation, OneNexus will also introduce a 501(c)(3) non-profit foundation that will call on the international oil and gas community to support the innovative solutions to suppressing greenhouse gas emissions.

"Existing solutions are inadequate," Sanchez adds. "We started a company that is capable of tackling the problem head-on and that enables energy companies to proactively be part of the solution."

Sanchez was the founder and former CEO of Sanchez Energy Corporation, a multi-billion dollar energy production company with assets in the Eagle Ford Shale, and has held finance and analysis positions at JP Morgan Investment Banking and Zix Corp. (NASDAQ: ZIXI). He has brought over energy industry specialists and financial professionals to build out his team, with subject matter experts in petroleum engineering, chemical engineering, data science, and systems management.

OneNexus joins a growing group of Houston organizations focused on clean energy and reduction of greenhouse gas emissions. Recent research from Rice University showed that the city is uniquely ready for the energy transition.

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”