The UTHealth Behavioral Sciences Center, set to open next year, will be unlike anything in Houston. Rendering courtesy of Perkins and Will

Film and TV portrayals of psychiatric hospitals have driven a narrative based in cold, clinical rooms and unwelcoming corridors. That picture couldn't be more inaccurate when it comes to Houston's first public mental health hospital in more than three decades. Breaking stigmas and setting a new bar for design, the UTHealth Behavioral Sciences Center is set to open its doors in late 2021.

UTHealth has brought on architecture firm Perkins and Will to design the upcoming mental health facility. The behavioral health campus will be the largest facility of its kind in the United States, becoming a place to train future physicians and specialists. Located near Texas Medical Center, the space will consist of two buildings connected by a glazed bridge, surrounded by a tranquil green space.

The 220,000-square-foot facility includes 264 new inpatient beds and will provide access to mental healthcare, substance use intervention and treatment, and medical care via integrated treatment programs.

"Knowing that behavioral and mental health is a critical aspect of one's holistic well-being, our team was thoughtful in approaching each design decision through research and with the interest of promoting health," says Diana Davis, principal and managing director of the Houston studio of Perkins and Will.

Creating the calm

Rendering courtesy of Perkins and Will

Each element in the space was created with the intention of creating a peaceful environment for patients and staff. From a warm color palette to scenic views, the architecture will play a role in soothing patients and offering a relaxing space.

"We were working directly with a researcher who had done a lot of work on the impact of lighting environments for helping to establish a stronger sense of circadian rhythm in the behavioral health environment," explains Davis.

Tunable lighting fixtures that can shift to warmer hues at certain times of day were one of the intentional designs featured throughout the space.

Insomnia can arise in various mental health disorders and can even be a side effect of certain medications. According to the National Alliance on Mental Illness, approximately 50 percent of insomnia cases are related to depression, anxiety or psychological stress.

"If you've ever suffered from a little bit of insomnia, you can imagine that that probably makes the treatment process that much harder. So anything we could do as design professionals to encourage a relaxing, sleeping space was very important," says Sarah Rolfvondenbaumen, a project architect at Perkins and Will.

Like light, sound can be a crucial element in creating an ambiance. The units in the UTHealth Behavioral Sciences Center is built for 24 patients — now imagine 24 patients talking in a room. "It could get very loud," says Rolfvondenbaumen, "We focused a lot on how to reduce that sound."

Rolfvondenbaumen explained how many hospital settings use two different types of acoustics that are "necessary to make a good space to be in." Sound transmission class (STC) is the measurement of how sound travels between two different spaces, and noise reduction coefficient (NRC) is a number value that describes the average sound absorption of material.

"We used a very high in our NRC ceiling tile where applicable. . .that really helps capture the sound that is bouncing around a room and displacing it instead of reflecting it back down," says Rolfvondenbaumen. The design also changes the planes of the space, avoiding the typical square layout and giving rooms non-90 degree angles.

Perkins and Will will also be collaborating with researchers at the UTHealth Science Center to research the impact of noise reduction. By comparing the space patients are in now vs. the new building, Davis hopes to conduct "a study that would show that, hopefully, by reducing the noise that we're also able to reduce adverse events and contribute to that healing environment."

Materials matter

Rendering courtesy of Perkins and Will courtesy of Perkins and Will

Outside of choosing noise-reducing materials, Perkins and Will made a commitment to using sustainable items within the facility.

"We had a very rigorous process of selecting the interior finishes to make sure that they were good for the environment or at least good for the people who are living in the space," says Rolfvondenbaumen.

Material health was a big priority because "in trying to heal people's minds and bodies, we weren't subjecting them to materials that themselves might be carcinogens or involve an excess of pollutants in the process of being created," explains Davis.

A welcoming space

Rendering courtesy of Perkins and Will

"It was really important to us in the design to deinstitutionalize the look of the building," explains Davis, "To try to keep the height down so that it felt a little less intimidating so that it felt more like it was a part of its community."

To help patients transition from the hospital setting into the outside world, the campus includes a therapy mall. Offering opportunities for patients to practice interacting in everyday life, the therapy mall was created to be used in a multitude of ways. It can serve as a salon, boutique, fitness center, movie night spot, or music therapy space.

"One of my favorite features of the building is that the way it is designed is that the shared treatment spaces that are kind of the amenity spaces that serve multiple units are located on the ground floor and all wrap around one of the courtyards," explains Davis.

The common areas like the therapy mall and dining room feature natural light and picturesque views of the tree-filled courtyard. "We were very intentional about making sure that the key locations of therapy all had that direct communication to the outdoors and that ability to see out," says Davis.

Staff perks

Rendering courtesy of Perkins and Will

The healthcare field, especially during a pandemic, can be a stressful environment with high rates of employee burnout. The CDC has even published extensive guides for healthcare workers and first responders to help overcome the stress caused by COVID-19 and the healthcare system.

More than solely a relaxing space for patients, the UTHealth Behavioral Sciences Center is designed to make work comfortable for staff members, too. The facility's Support Pavilion holds an education center as well as break rooms, on-call sleep rooms, and a mother's room for staff.

"The Support Pavilion has its own entrance so that people coming and going are preapproved," explains Rolfvondenbaumen, "They have a badge reader so that they don't have to go through security scrutinization that the public entrance has."

Planning ahead

Rendering courtesy of Perkins and Will

Every Houstonian is, unfortunately, familiar with the city's flooding woes. The UTHealth Behavioral Sciences Center project started post-Hurricane Harvey, so flooding was undoubtedly on the mind of the Perkins and Will team.

Evacuating a healthcare building is unideal, especially a psychiatric facility. Measures were taken to prevent flooding and keep the hospital running on generator power, so patients could stay safe in the building. Just below the hospital, the facility features underground storage tanks that could fill an Olympic-sized swimming pool.

While weather can be planned for, a global pandemic is far less predictable. While the project with UTHealth was started prior to the coronavirus, the space is intentionally designed to allow patients to have flexibility throughout. Patients can choose to be in larger group settings or separate themselves into a breakout room, lending itself to social distancing guidelines.

While it's unclear whether Houston will be dealing with the COVID-19 pandemic at the close of next year, research shows the lasting mental health struggles the virus is creating. Davis foresees this project contributing "in a much more significant way" due to the unfortunate "need for care that we will have following this [pandemic] because of the mental stress and strain."

While mental and behavioral health has long-held stigmas, the UTHealth Behavioral Sciences Center will be both "welcoming and inviting," says Davis.

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Houston health tech co. lands NIH grant for AI cancer prediction tool

fresh funding

Houston-based CellChorus and Stanford Medicine were recently awarded a Phase I Small Business Innovation Research grant for the company's AI platform to test how certain cancer patients will respond to therapies.

The funding comes from the National Cancer Institute of the National Institutes of Health. According to a filing, the grant totaled just under $400,000.

CellChorus, which spun out from the University of Houston’s Technology Bridge, has developed TIMING (Time-lapse Imaging Microscopy In Nanowell Grids), which analyzes the behavior of thousands of individual immune cells over time and can identify early indicators of treatment success or failure.

The company will work with Stanford's Dr. David Miklos and Dr. Saurabh Dahiya, who have built the Bone Marrow Transplantation and Cell Therapy Biobank. The biobank manages and stores biological samples from patients treated at their clinic and in clinical trials.

"Predicting which patients will achieve durable responses after CAR-T therapy remains one of the most important challenges in the field,” Miklos said in a news release. “We aim to uncover functional cellular signatures that can guide treatment decisions and improve patient outcomes.”

The project will specifically profile cells from patients with relapsed/refractory large B-cell lymphoma (r/rLBCL). According to CellChorus, only about half of r/rLBCL patients who receive CAR-T therapy "achieve a durable, long-term remission." Others do not respond to therapy or experience relapse.

“The sooner we know whether a cancer therapy is working, the better. To maximize patient benefit, we need technology that can provide a robust and early prediction of response to therapy. The technology needs to be scalable, cost-efficient, and capable of rapid turnaround times,” Rebecca Berdeaux, chief scientific officer of CellChorus, added in the release. “We are excited to work with Drs. David Miklos and Saurabh Dahiya and their colleagues on this very important project.”

CellChorus has previously received SBIR grants from federal agencies, including a $2.5 million award in 2024 from its National Center for Advancing Translational Sciences (NCATS) and a $2.3 million SBIR Fast-Track award from the National Institute of General Medical Sciences in 2023.

Houston museum showcases America's founding documents in rare exhibit

Experience History

As the United States prepares to celebrate its 250th birthday, Houstonians have a chance to see rare documents from the founding of the nation. Freedom Plane National Tour: Documents That Forged a Nation, presented by the National Archives Foundation, will be on display at the Houston Museum of Natural Science through Monday, May 25.

The collection includes a rare engraving of the original Declaration of Independence; official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton; a draft of the Bill of Rights; the Treaty of Paris, the documented that recognized America's independence from Great Britain; and the tally of votes approving the Constitution.

The National Archives specifically chose Houston as one of only eight cities in the country to host the exhibit as a means to help the documents reach a wider audience outside of the main hub of semiquincentennial events in New England and the Washington, D.C. area.

"One of the things we decided when we put the tour together because we wanted to be off the East Coast," said Patrick Madden, CEO of the National Archives Foundation, who was onsite for the exhibit's opening in Houston. "There's a lot of 250th celebration stuff happening in the original 13 colonies. How do we get it to major markets where larger numbers of people can see it? So in the case of Houston, obviously, [is a] major market in this part of the country, but also we've partnered with the museum twice before with National Archives exhibits, so we knew that they would be up to the task of handling the exhibit and the crowds."

The star of the collection is a rare engraving of the original Declaration of Independence. Secretary of State and future president John Quincy Adams commissioned 200 exact replicas of the document from engraver William J. Stone in 1823. Less than 50 now remain. Madden joyfully pointed out that there are errors in this document, a potent reminder that the men who forged a nation made mistakes.

"There's a couple of typos in it where they had to make corrections," said Madden. "So even the founders, you know, they're all human. That resonates because here these people are making this move against the most powerful nation in the world and putting their lives on the line for a country based on ideas."

Other impressive parts of the collection include official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton, as well as one of the drafts of the Bill of Rights. Many states would not ratify the Constitution until certain rights were included in the document, leading to Washington going on a national tour assuring state leaders enshrining protections was first on the list. The draft copy on display specifically shows the First Amendment in progress.

Houston is the fourth stop on the exhibition's tour, which will take the documents to Denver, Miami, Dearborn, and Seattle through the summer. Freedom Plane is just one part of a larger patriotic celebration at the HMNS, which includes a film series celebrating American science and culture and general Americana decoration throughout the main hall.

Admission to Freedom Plane is free to the public, but separate from general admission to the museum. Space is limited, and passes are available on a first-come, first-serve basis. Non-members should expect long waits or the possibility that the day's passes are sold out. Only museum members can reserve passes for specific times. Flash photography is prohibited due to the fragile nature of the documents.

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This article originally appeared on CultureMap.com.

Houston quantum energy chip startup emerges from stealth with $12M round

seed funding

Houston-based Casimir has emerged from stealth with a $12 million seed round to commercialize its quantum energy chip.

The round was led by Austin-based Scout Ventures. Lavrock Ventures, Cottonwood Technology, Capital Factory, American Deep Tech, and Tim Draper of Draper Associates also participated in the round. The oversubscribed round exceeded the company’s original $8 million target, according to a news release.

Casimir’s semiconductor chips can generate power from quantum vacuum fields without the need for batteries or charging. The company plans to commercialize its first-generation MicroSparc chip by 2028.

The MicroSparc chip measures 5 millimeters by 5 millimeters and is designed to produce 1.5 volts at 25 microamps, comparable to a small rechargeable battery, without degradation and no replacement cycle.

“Casimir represents exactly the kind of breakthrough dual-use technology Scout Ventures was built to back,” Brad Harrison, founder and managing partner at Scout Ventures, said in the release. “This is based on 100 years of science and we’re finally approaching a commercial product … We’re proud to lead this round and support Casimir’s journey from applied science to deployed technology.”

Casimir says it aims to scale its technology across the ”full power spectrum,” including large-scale energy systems that can power homes, commercial infrastructures and electric vehicles.

Casimir's scientific work has been supported by DARPA-funded nanofabrication research and its technology was incubated at the Limitless Space Institute (LSI). LSI is a nonprofit that works to innovate interstellar travel and was founded by Kam Ghaffarian. Technology investor and serial entrepreneur Ghaffarian has been behind companies like X-energy, Intuitive Machines, Axiom Space and Quantum Space.

Harold “Sonny” White, founder and CEO of Casimir, believes the technology can power devices for years without replacements.

“Millions of devices will operate for years without a battery ever needing to be replaced or recharged because we have engineered a customized Casimir cavity into hardware capable of producing persistent electrical power,” White added in the release. “I spent nearly two decades at NASA studying how we power humanity’s future. That work led me to the Casimir effect and the quantum vacuum, where new tools have allowed us to build on a century of scientific knowledge and bring abundant power to the world.”