Fill next week's calendar with these can't miss online events from The Houston Innovation Summit. Photo via Getty Images

Back for its fourth year, The Houston Innovation Summit has tons of online, interactive events lined up — starting today.

THIS, just like last year, runs on the same week of Global Entrepreneurship Week, which is focused on education, ecosystems, inclusion, and policy this year. Grace Rodriguez, CEO and executive director of Impact Hub Houston, which hosts THIS, says she focused on incorporating these themes into the programming.

"The focus on education and policy is really interesting to me — it's not just about tech and business anymore," Rodriguez says. "It's really about how we are supporting businesses in the face of the pandemic, climate change crises — floods, fires, hurricanes — the entire world is being affected by these crises. ... [We need to focus on] how we are making sure that people are aware of everything that's happening and how we can innovate solutions."

For a complete list of THIS events, head to the website. Here are the events you should make sure not to miss.

Friday, November 13 — Climathon

The second annual Climathon kicks off THIS beginning today, and continues with two more events on November 17 and November 20. The interactive idea-a-thon is seeking tech specialists, policy experts, and anyone interested in helping prevent the degradation of the planet. For full details on the event and to register, click here.

Monday, November 16, at noon — #THIS2020 Pre-Game AMA with InnovationMap Editor Natalie Harms

A bit of a self-serving listing, but a cool event nonetheless. Join me for an ask-me-anything style chat with Grace Rodriguez of Impact Hub Houston at noon on Monday. Click here to learn more and register.

Monday, November 16, at 3 pm — #THIS2020 Kick-Off: The State of Houston Startups and Small Businesses

Join Houston Exponential for the official kick-off event at 3 pm on Monday. Learn from founders, business mentors, and SBA leaders on how to take advantage of Houston's best available resources to take your company to the next level. For the full agenda and to register, click here.

Wednesday, November 18, at 11:30 am — On Both Sides: Post-Election Conversation on The State of Texas, Startups, and Our Union

Join Impact Hub Houston on Wednesday at 11:30 am for a post-election conversation with diverse startup and community leaders on The State of Texas, Startups, and Our Union. After the initial conversation among the panelists, audience members can ask questions for discussion on the 2020 election, outcomes, and the political landscape that lies ahead. Click here to learn more and register.

Wednesday, November 18, at 3 pm — Houston Originals

Blinds.com has been one of Houston's biggest success stories, but also have been some of their industries' biggest success stories. Behind one of the largest acquisitions in the history of the e-comm is founder, Jay Steinfeld.

Hear from this Houston Original on Wednesday at 3 pm as he shares his true, unfiltered experiences in launching and scaling some of the most prominent companies in business today.

To learn more and save your spot, click here.

Thursday, November 19, at 11 am — Refining Equity

Learn how black entrepreneurs are redefining "equity" and launching new ventures for financial resilience, investment, and wealth generation. Click here to learn more and register for this event on Thursday at 11 am.

Friday, November 20, at 11 am — HCC IDEAS Pitch Competition

The IDEAS Pitch competition (Virtual Competition) on next Friday at 11 am is designed for students to share their creative ideas and social innovations. Individuals or teams can compete in the competition by delivering a pitch to a team of judges. Students should pitch a product or service that explores innovative approaches to answering pressing sustainability and societal needs. Click here to learn more and register.

Friday, November 20, at 3 pm. — The Listies

Let's toast to the entrepreneurial spirit of Houston in a time when celebrating victories is more important than ever. Introducing the Listies, brought to you Houston Exponential and InnovationMap, commemorating the launch of HTX TechList, Houston's innovation discovery platform. Check out the finalists by clicking here. To learn more and to register for the event next Friday at 3 pm, click here.

Grace Rodriguez, CEO and executive director of Impact Hub Houston, has a few weeks ahead of her. Courtesy of Grace Rodriguez

Houston nonprofit introduces new startup incubator ahead of impact-focused innovation week

accelerate

Impact Hub Houston — the local chapter of a nonprofit focused on supporting startups in the social impact space — has a lot on its plate this month.

Not only is next week The Houston Innovation Summit — the fourth annual week of entrepreneurship programming — as well as the second annual Climathon, but the organization has also just launched a new business incubator program.

Accelerate is a program that Impact Hub has offered across 17 international markets. Houston's new chapter already has a few Houston startups involved — including Potentia Workforce and McMac CX. Structured as an ongoing accelerator with mentorship, education, and support, the program is currently accepting new members.

"We actually sit down with each new Accelerate member and then go through a diagnostic interview to help them understand what stage they're at," says Grace Rodriquez, CEO and executive director of Houston Impact Hub. "And then we create a development strategy with them."

Whether the Accelerate member needs one-on-one mentorship, specialized education, or more, the program match makes each member's needs. EY is a network partner and — since everything is virtual — member companies have access to international experts through Impact Hub and its partners' networks.

"The ideal entrepreneur for the Accelerate membership is somebody who has already developed a solution — at least an MVP — for their social venture, whether it's a product or a service," Rodriguez says.

She cites Potentia as an example. The startup helps find jobs for adults with special needs, as well as educate corporations on how to work with and collaborate with these individuals. The company already has data and momentum, and the Accelerate program is helping the company to get to it's next stage.

"The idea is that we help people ladder up — no matter what stage you're at," Rodriguez says.

While growing the new program's membership — Rodriguez says it's her goal to get to 10 member companies my early next year — she's also focused on The Houston Innovation Summit and Impact Hub's Climathon.

The second annual Climathon, which begins Friday, November 13, has evolved since last year in a number of ways. First of all, it's completely virtual — which poses its own set of challenges and opportunities. Additionally, the event has several new partners — most of which didn't even exist in Houston last year, like Greentown Houston and Evolve Houston.

One of the biggest, most exciting changes for Rodriguez is the structure. While last year's event functioned as a hackathon, this year attendees can expect thought-provoking programming and collaboration.

"Last year, [Climathon] was directed at people who were more tech savvy," Rodriguez says. "What we found is people who are interested in climate action are a lot of times policy oriented or community activists and they don't know how they can plug into the tech space. It's more of an idea-a-thon. You don't have to develop a tech solution, but we can think about how we can activate more people for climate change."

Last year's Climathon took place during October. WIth it moving to November this year, it coincides with THIS, adding even more events to the week-long, impact-focused summit. THIS, which was designed to run alongside Global Entrepreneurship Week, also considers that week's themes, which are: education, ecosystems, inclusion, and policy.

"The focus on education and policy is really interesting to me — it's not just about tech and business anymore," Rodriguez says. "It's really about how we are supporting businesses in the face of the pandemic, climate change crises — floods, fires, hurricanes — the entire world is being affected by these crises. ... [We need to focus on] how we are making sure that people are aware of everything that's happening and how we can innovate solutions."

Log on to one of these informative online events happening throughout the rest of the month. Getty Images

10+ can't-miss virtual business and innovation events in Houston for November​

Where to be online

November is usually the last busy month for business events before the end of the year and ahead of the holidays, and this year — even though events have pivoted to virtual gatherings — is no different.

From panels and ask-me-anything meetings to summits and startup competitions, here are over 10 Houston innovation events you can attend virtually via online meetings. This month in particular there's the return of The Houston Innovation Summit and the brand new awards program called, The Listies (nominate now for those). Be sure to register in advance, as most will send an access link ahead of the events.

November 5 — Dell Technologies Ask Me Anything

Dell Technologies is hosting an "Ask Me Anything" session for the Ion community. During this time, attendees can ask experts anything in regards to IT pain points during these times. Entrepreneurs may also use this time to brainstorm the back end IT Infrastructure of their business.

The event will take place online on Thursday, November 5, at 10 am. Register here.

November 5-6 — Greentown Labs Climatetech Summit

Join Greentown Labs for its first Climatetech Summit for a deep dive into scaling climate action. Across the two days, attendees will engage with Greentown's pillars of climate action — technology, finance, policy, and justice — discover groundbreaking startups and their climatetech solutions, learn from industry experts, and forge meaningful connections with entrepreneurs, investors, business leaders, policymakers, startup support organizations, and other climate champions.

The event will take place online on Thursday, November 5, and Friday, November 6. Register here.

November 10 — Igniting Leadership: The State of COVID Vaccines

Join Ignite Healthcare Network for a special night of discussion hosted by IGNITE Steering Committee member Susan Feigin Harris about the status of COVID19 vaccine development with Dr. Maria Elena Bottazzi, Co-director of Texas Children's Center for Vaccine Development.

The event will take place online on Tuesday, November 10, at 6 pm. Register here.

November 10-12 — Texas Life Sciences Forum

The Texas Life Science Forum is the premier life science event in Texas that brings together members from industry, emerging life science companies, academic, and investors. The 2020 event will be virtual and will still be the "must attend" event for anyone in the life science industry in Texas or affiliated with innovation at the life science academic institutions. This event represents an opportunity to meet investors, learn about promising life science companies, to learn about opportunities for entrepreneurs, investment professionals, big pharma, academics and business executives serving the life science industry.

The event will take place online on Tuesday, November 10, to Thursday, November 12. Register here.

November 12 — Plaza Tec: Funding Fundamentals

Though Latinx-owned businesses and startups make up at least 38 percent of businesses in the Houston area, there is still a lack of access to capital blocking growth and progress for Latinx founders.

In this discussion presented by The Ion, representatives from baMa and NextSeed will join together to discuss angel investing and crowdfunding options for Latinx founders and what challenges one might face when seeking capital.

The event will take place online on Thursday, November 12, at 5:30 pm. Register here.

November 12 — Women in Tech and Biz

If you're interested in hearing from some badass women in tech and business, come to the virtual Women in Tech + Biz event created by the Liu Idea Lab for Innovation and Entrepreneurship. The event will be split into two sections — one focused on entrepreneurship and the other focusing more on software and engineering — followed by networking.

The event will take place online on Thursday, November 12, at 6 pm. Register here.

November 13 — Climathon 2020: Hacking Solutions to Houston’s Climate Challenges

On Earth Day this year, the City of Houston published its first Climate Action Plan. The plan is the culmination of thousands of volunteer time from industry professionals, policy stakeholders, and community advocates. Together the working groups have laid out a concise plan to address the climate challenges that Houston faces along with maintaining a leadership role in the energy transition. This year's Climathon will look to realize some of the goals of the plan through design sprints led by local subject matter experts in the areas of transportation, energy innovation, building optimization, and materials management.

The event will take place online on Friday, November 13, at 1 pm. Register here.

November 16-20 — The Houston Innovation Summit

The Houston Innovation Summit — THIS — celebrates Houston's innovation ecosystem during Global Entrepreneurship Week (GEW). THIS responds to 2020 with a special focus on the intersection of Impact and Innovation, spotlighting Houstonians at the forefront of education, ecosystems, inclusion, and policy. Join Impact Hub Houston and Houston's startup and small business community for a week of exciting programs and connect with the thinkers, doers, makers and innovators driving Houston forward.

The event will take place online on Monday, November 16, to Friday, November 20. Register here.

November 17 — Struggles and Bubbles: Pivoting during a Pandemic

Join General Assembly Houston to listen to a panel of startup founders who will share their journey and entrepreneurial struggles, and what it really takes to launch a startup during global pandemic, and scale a startup.

The event will take place online on Tuesday, November 17 at 5 pm. Register here.

November 17-19 — Capital Factory's Texas Startup Roadshow

For the first time, Capital Factory is taking its roadshow online. For three days, the organization will be introducing investors to the various innovative cities across the Lone Star State.

Houston will be the city of focus on Wednesday, November 18.

The event will take place online on Tuesday, November 17, to Thursday, November 19. Register here.

November 20 — The Listies

Let's toast to the entrepreneurial spirit of Houston in a time when celebrating victories is more important than ever. Introducing the Listies, brought to you Houston Exponential and InnovationMap, commemorating the launch of HTX TechList, Houston's innovation discovery platform.

The event will take place online on Friday, November 20, at 3 pm. Register here.

Houston startup development organizations have banded together for the third annual Houston Innovation Summit. Getty Images

Here's what events to attend each day during The Houston Innovation Summit

Where to be

For the third year, The Houston Innovation Summit is taking over the town to promote entrepreneurship and innovation within the city.

THIS begins today and runs through the weekend. Each day represents a theme — all pertinent to Houston. Impact Hub Houston has worked with other local startup development organizations to curate the programming for the week. Grace Rodriguez, CEO and executive director for Impact Hub Houston, says Houston has the innovation infrastructure by now, and now it's about execution.

"For 2019, the goal is now how do we go from inclusion to integration," Rodriguez says on a recent episode of the Houston Innovators Podcast. "I think we're at that step now of becoming more inclusive as a community."

THIS, just like last year, runs on the same week of Global Entrepreneurship Week, which is why today's programming starts with a global focus. Follow along on a global scale with #GEWecosystems.

For a complete list of THIS events (most of which are free and all over town), head to the website. Here are the events you should make sure not to miss.

Monday — Houston: We're Global

Starting strong, the first can't-miss event is the kickoff party. The free event is in the Amegy Building downtown (1801 Main Street), which is currently being transformed into The Cannon Houston's new Launch Pad. The event runs from 4 to 5:45 pm, and you can expect networking and interactive discussions on Houston's innovation ecosystem's growth and potential. Click here to register.

Tuesday: This Is Houston

While GotSpot's Female Founder Luncheon at MassChallenge is a good one to make if you can, the big event this day is Houston Exponential's 2020 Vision event. Basically an open house-style event, attendees at this free event can learn how to engage with HX and what the organization has planned for 2020. InnovationMap and Accenture are teaming up for a fireside chat about the diversity and potential in Houston. Click here to register.

Wednesday: Fresh Perspectives

The fight for technology and innovation is on. The first Houston Digital Fight Club is on Wednesday, November 20, and will feature five fights between industry experts on topics like cybersecurity, sustainable energy, primary care, and more. Audience members get to decide on a winner, and there will be tons of opportunities for networking. The event is $30 per person and will be at White Oak Music Hall. InnovationMap and Accenture are the lead sponsors. Click here to register.

If you can't make this evening event, WeWork Food Labs is cooking up a special event to discuss food innovation in Houston. Click here to register.

Thursday: The Next Generation

While the week so far has been centered around the future of Houston, Thursday focuses specifically on the next generation of people who will be powering the ecosystem. And, of course, money is essential to that equation. Join for a panel from top investor leaders at an event focused on next generation investing at HCC SouthEast Felix Fraga Academic Campus - East End. The panel itself is $5, but for $15 you can also catch two other discussions on campus that day. Click here to register.

For an early bird alternative, Mercury Fund is hosting a Female Founders breakfast at 7:30 am at their office (3737 Buffalo Speedway, Suite 1750). This one is free to attend. Click here to register.

Friday: Integrating Innovation

Friday's events all take place at The Cannon Houston (1334 Brittmoore Road), and there's a specific focus on military technology and military-affiliated entrepreneurs. The Southwest Muster Across America Tour in Houston is from 1 to 6 pm and will consist of an expo, pitch competition, expert talks, and more. The WeWork Veterans in Residence Program Powered by Bunker Labs will show off their companies, and Bunker Labs has teamed up with Ford Fund to host pitch competitions for veteran and military spouse entrepreneurs. Houston is one of seven stops for the competition, and the top two showcase pitches will win $5,000 and $3,500 from the Ford Fund to help support their businesses. Click here to register.

Following this event is Impact Hub's monthly Fuckup Night, where entrepreneurs share their stories of success, struggle, and failure. Click here to register.

Weekend: Innovation Education

The week wraps up with events focusing on education. One not to miss is on Saturday: The HCC IDEAS Pitch Competition. The competition begins at 1 pm and there is $2,500 on the line. Any HCC student is able to apply to pitch. Click here to register.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.