CPRIT recently granted $93 million to 61 organizations and scientists, including many in Houston, to advance cancer research. Carter Smith/Courtesy of MD Anderson

Several prominent cancer researchers are coming to the Houston area thanks to $22 million in grants recently awarded by the Cancer Prevention and Research Institute of Texas (CPRIT).

The biggest CPRIT recruitment grant — $6 million — went to genetics researcher Jean Gautier. Gautier, a professor of genetics and development at Columbia University’s Institute for Cancer Genetics, is joining the University of Texas MD Anderson Cancer Center to continue his research.

The website for Gautier’s lab at Columbia provides this explanation of his research:

“The main objective of our research is to better understand the molecular mechanisms responsible for the maintenance of genome stability. These controls are lost in cancer, which is characterized by genomic instability.”

Aside from his work as a professor, Gautier is co-leader of the Herbert Irving Comprehensive Cancer Center’s Cancer Genomics and Epigenomics Program at Columbia.

Other recipients of CPRIT recruitment grants include:

  • $2 million to recruit Xun Sun from the Scripps Research Institute to the University of Texas Medical Branch at Galveston.
  • $2 million to recruit Mingqi Han from the University of California, Los Angeles to MD Anderson.
  • $2 million to recruit Matthew Jones from Stanford University to MD Anderson.
  • $2 million to recruit Linna An from the University of Washington to Rice University.
  • $2 million to recruit Alissa Greenwald from the Weizmann Institute of Science to MD Anderson.
  • $2 million to recruit Niladri Sinha from Johns Hopkins University to the Baylor College of Medicine.
  • $2 million for Luigi Perelli to stay at MD Anderson so he can be put on a tenure track and set up a research lab.
  • $2 million for Benjamin Schrank to stay at MD Anderson so he can be put on a tenure track and set up a research lab.

Over $20.2 million in academic research grants were awarded to researchers at:

  • Baylor College of Medicine
  • Houston Methodist Research Institute
  • Rice University
  • Texas Southern University
  • University of Houston
  • University of Texas Health Science Center at Houston
  • University of Texas MD Anderson Cancer Center
  • University of Texas Medical Branch at Galveston

In addition, nearly $4.45 million in cancer prevention grants were awarded to one researcher at the University of Texas Medical Branch at Galveston and another at Texas Southern University.

Also, five Houston businesses benefited from CPRIT grants for product development research:

  • Allterum Therapeutics, $2,999,996
  • CTMC, $1,342,178
  • Instapath, $900,000
  • Prana Surgical, $900,000
  • InformAI, $465,188

“Texas is a national leader in the fight against cancer,” said Kristen Pauling Doyle, CPRIT’s CEO. “We can measure the return on investment from CPRIT grants … not only in the economic benefits flowing from increased financial activity and jobs in the state, but more importantly in the cancers avoided, detected early, and treated successfully. Thanks to the Legislature’s vision, this commitment is saving lives.”

Overall, CPRIT approved 61 grants totaling more than $93 million in this recent round of funding.

The next phase of the Houston Spaceport will build out connectivity and workforce training. Rendering via Houston Airports

Houston Spaceport takes off with second phase of development

ready for liftoff

Since the Houston Spaceport secured the 10th FAA-Licensed commercial spaceport designation in 2015, the development's tenants have gone on to secure billions in NASA contracts. Now, the Houston Spaceport is on to its next phase of growth.

“Reflecting on its meteoric rise, the Spaceport has seen remarkable growth in a short span of time. From concepts on paper to the opening of Axiom Space, Collins Aerospace, and Intuitive Machines, the journey has been nothing short of extraordinary,” says Arturo Machuca, director of Ellington Airport and the Houston Spaceport, in a news release. “These anchor tenants, collectively holding about $5 billion in contracts with NASA and other notable aerospace companies, are not just shaping the future of space exploration but injecting vitality into Houston’s economy.”

The next phase of development, according to Houston Airports, will include:

  • The construction of a taxiway to connect Ellington Airport and the Spaceport
  • The construction of a roadway linking Phase 1 infrastructure to Highway 3
  • The expansion of the EDGE Center, in partnership with San Jacinto College

Rendering via Houston Airports

The Houston Spaceport's first phase completed in 2019. Over the past few years, tenants delivered on their own buildouts. Last year, Intuitive Machines moved into its new $40 million headquarters and Axiom Space opened its test facility. In 2022, Collins Aerospace cut the ribbon on its new 120,000 square-foot facility.

“The vision for the Houston Spaceport has always been ambitious,” says Jim Szczesniak, director of Aviation for Houston Airports. “Our vision is to create a hub for aviation and aerospace enterprises that will shape the future of commercial spaceflight.”

Educational partners have also revealed new spaces, including San Jacinto College's EDGE Center, which broke ground in July of 2019, finally celebrated its grand opening in 2021. Last year, Texas Southern University got the greenlight to operate an aeronautical training hub on a two-acre site at Ellington Airport.

“By providing the education and training needed to sustain jobs in the rapidly evolving space industry, the Spaceport is not only attracting companies but also nurturing the talent that will drive Houston's aerospace sector forward,” continues Szczesniak in the release.

Texas Southern University got the greenlight for funding for its flight academy. Photo courtesy of Houston Airport System

City approves $5.5M investment for Houston flight school

greenlight

Houston City Council approved Houston Airports to use $5.5 million from its Airport Improvement Fund to build the Texas Southern University Flight Academy at Ellington Airport.

The new facility will add to student learning with TSU’s aviation program and internships. Construction will begin in May of 2024 with an expected completion of May 2025.

“The investment in this facility allows Houston to remain at the forefront of supporting the rapid growth of the air transportation industry in the United States,” Mayor Sylvester Turner says in a news release. “I am honored that the City of Houston is taking the initiative to build this facility, which will provide numerous opportunities for Houstonians in the future."

TSU expanded its flight training fleet at Ellington Airport with the addition of a new Cessna 172, which brings the university to nine aircrafts that are available to help expand the program.TSU also has a virtual airport laboratory that trains pilots, air traffic controllers, and airport officers.

Construction is expected to begin in May of 2024 with an anticipated completion of May 2025. Rendering courtesy of Houston Airport Systen

The facility will be two acres and built on land accessible to an existing taxi-lane connection. The facility includes a 24,000 square foot aircraft hangar, an 11,000 square feet of aircraft apron, a 4,200 square feet of office/training/classroom space, an 8,000 gallon above-ground aviation fuel tank, and vehicle parking.

“This new facility is a major step toward Texas Southern University becoming the premier destination for training pilots and aviation professionals of the future,” TSU Interim President Mary Evans Sias says in a news release. “Our aviation program has reached heights in achievement that are unprecedented for the state of Texas. We look forward to the future aviators who will come through these doors and leave prepared to seize the opportunities in aviation, which we know are only increasing. We are deeply appreciative of the City of Houston for making this investment into TSU, and we know the return on this investment will be worthwhile.”

The Houston City Council approved a memorandum of agreement this past May for five years between Houston Airports and TSU.

“Houston Airports is a proud partner of TSU as it educates and inspires the next generation of pilots, mechanics and air traffic controllers,” Mario Diaz, director of Aviation for Houston Airports, says in a news release. “From training pilots during World War 1, and NASA astronauts as they prepared to step on the moon, to now training the next generation of aviation professionals, Ellington Airport continues to play a crucial role in Houston’s aviation history.”

Here's what Houston tech and startup news trended this year on InnovationMap in space tech. Image via Getty Images

Top Space City news of 2023: New Houston unicorn, an IPO, spaceport development, and more

year in review

Editor's note: As the year comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. In the Space City, there were dozens of space tech stories, from a space tech company reaching unicorn status to another completing its IPO. Here are five Houston space tech-focused articles that stood out to readers this year — be sure to click through to read the full story.


Local university gets green light to launch new building at Houston Spaceport

City of Houston has entered into an agreement with Texas Southern University to develop an aviation program at the Houston Spaceport. Photo via fly2houston.com

With a financial boost from the City of Houston, the aviation program at Texas Southern University will operate an aeronautical training hub on a two-acre site at Ellington Airport.

The Houston Airport System — which runs Ellington Airport, George Bush Intercontinental Airport, Hobby Airport, and Houston Spaceport — is chipping in as much as $5 billion to build the facility, which will train aeronautical professionals.

On May 3, the Houston City Council authorized a five-year agreement between the airport system and TSU to set up and operate the facility. Continue reading the full story from May.

Houston space tech startup closes deal to IPO

Intuitive Machines will be listed on Nasdaq beginning February 14. Photo via intuitivemachines.com

It's official. This Houston company is live in the public market.

Intuitive Machines, a space tech company based in Southeast Houston, announced that it has completed the transaction to merge with Inflection Point Acquisition Corp., a special purpose acquisition company traded on Nasdaq.

“We are excited to begin this new chapter as a publicly traded company,” says Steve Altemus, co-founder, president, and CEO of Intuitive Machines, in a news release. “Intuitive Machines is in a leading position to replace footprints with a foothold in the development of lunar space. With our launch into the public sphere through Inflection Point, we have reached new heights financially and opened the doors for even greater exploration and innovation for the progress of humanity.”

The transaction, which was originally announced in September, was approved by Inflection Point’s shareholders in a general meeting on February 8. As a result of the deal, the company will receive around $55 million of committed capital from an affiliate of its sponsor and company founders, the release states. Continue reading the full story from February.

Houston to host 6 Italian aerospace companies with new program

Six Italian companies are coming to the Space City to accelerate their businesses thanks to a new program. Photo via nasa.gov

It's an Italian invasion in Houston — and it's happening in the name of accelerating innovation within aerospace.

For the first time, Italy has announced an international aerospace-focused program in the United States. The Italian Trade Agency and Italian Space Agency will partner with Space Foundation to launch Space It Up, an initiative that will accelerate six companies in Houston.

“The launch of Space It Up marks a pivotal moment in our ongoing commitment to nurturing innovation and facilitating global partnerships," Fabrizio Giustarini, Italian Trade Commissioner of Houston, says in a news release. "This program serves as a testament to the collaborative spirit that defines the aerospace industry. It represents the convergence of Italian ingenuity and Houston's esteemed legacy in space exploration, setting the stage for unprecedented advancements." Continue reading the full story from August.

Houston space tech startup raises $350M series C, clinches unicorn status

Axiom Space CEO Michael Suffredini (right) has announced the company's series C round with support from Aljazira Capital, led by CEO Naif AlMesned. Photo courtesy of Axiom Space

Houston has another unicorn — a company valued at $1 billion or more — thanks to a recent round of funding.

Axiom Space released the news this week that it's closed its series C round of funding to the tune of $350 million. While the company didn't release its valuation, it confirmed to Bloomberg that it's over the $1 billion threshold. Axiom reports that, according to available data, it's now raised the second-most funding of any private space company in 2023 behind SpaceX.

Saudi Arabia-based Aljazira Capital and South Korea-based Boryung Co. led the round. To date, Axiom has raised over $505 million with $2.2 billion in customer contracts, according to the company.

“We are honored to team with investors like Aljazira Capital, Boryung and others, who are committed to realizing the Axiom Space vision,” Axiom Space CEO and president Michael Suffredini says in a news release. “Together, we are working to serve innovators in medicine, materials science, and on-orbit infrastructure who represent billions of dollars in demand over the coming decade. Continue reading the full story from August.

Texas university to build $200M space institute in Houston

Texas A&M University will build a new facility near NASA's Johnson Space Center. Photo courtesy of JSC

Texas A&M University's board of regents voted to approve the construction of a new institute in Houston that hopes to contribute to maintaining the state's leadership within the aerospace sector.

This week, the Texas A&M Space Institute got the greenlight for its $200 million plan. The announcement follows a $350 million investment from the Texas Legislature. The institute is planned to be constructed next to NASA’s Johnson Space Center in Houston.

“The Texas A&M Space Institute will make sure the state expands its role as a leader in the new space economy,” John Sharp, chancellor of the Texas A&M System, says in a news release. “No university is better equipped for aeronautics and space projects than Texas A&M.” Continue reading the full story from August.

Houston is in the running to receive millions from a program from the National Science Foundation. Photo via Getty Images

Houston named semifinalist for major energy transition funding opportunity

making moves

The National Science Foundation announced 34 semifinalists for a regional innovation program that will deploy up to $160 million in federal funding over the next 10 years. Among the list of potential regions to receive this influx of capital is Houston.

The Greater Houston Partnership and the Houston Energy Transition Initiative developed the application for the NSF Regional Innovation Engine competition in collaboration with economic, civic, and educational leaders from across the city and five regional universities, including the University of Houston, The University of Texas at Austin, Texas Southern University, Rice University, and Texas A&M University.

The proposed project for Houston — called the Accelerating Carbon-Neutral Technologies and Policies for Energy Transition, or ACT, Engine — emphasizes developing sustainable and equitable opportunities for innovators and entrepreneurs while also pursuing sustainable and equitable energy access for all.

“The ACT Engine will leverage our diverse energy innovation ecosystem and talent, creating a true competitive advantage for existing and new energy companies across our region," says Jane Stricker, senior vice president of energy transition and executive director for HETI, in a statement. "Texas is leading the way in nearly every energy and energy transition solution, and this Engine can catalyze our region’s continued growth in low-carbon technology development and deployment."

If Houston's proposal is selected as a finalist, it could receive up to $160 million over 10 years. The final list of NSF Engines awards is expected this fall, and, according to a release, each awardee will initially receiving about $15 million for the first two years.

"Each of these NSF Engines semifinalists represents an emerging hub of innovation and lends their talents and resources to form the fabric of NSF's vision to create opportunities everywhere and enable innovation anywhere," NSF Director Sethuraman Panchanathan says in a news release. "These teams will spring ideas, talent, pathways and resources to create vibrant innovation ecosystems all across our nation."

The NSF selected its 34 semifinalists from 188 original applicants, and the next step for Houston is a virtual site visit that will assess competitive advantages, budget and resource plans for R&D and workforce development, and the proposed leadership’s ability to mobilize plans into action over the first two years.

"Houston is poised, like no other city, to lead the energy transition. The ACT Engine presents a remarkable opportunity to not only leverage the region's unparalleled energy resources and expertise but also harness our can-do spirit. Houston has a proven track record of embracing challenges and finding innovative solutions,” says Renu Khator, president of the University of Houston, in the statement. “Through the collaborative efforts facilitated by the ACT Engine, I am confident that we can make significant strides towards creating a sustainable future that harmonizes economic growth, environmental protection and social equity."

NSF Engines will announce awards this fall after a round of in-person interviews of finalists named in July. With Houston's track record for building thriving industry hubs in energy, health care, aerospace, and the culinary arts, the region is eager to establish the next generation of leaders and dreamers responding to some of the greatest economic and societal challenges ever seen in America.

“Our energy innovation ecosystem is inclusive, dynamic, and fast growing," says Barbara Burger, energy transition adviser and former Chevron executive, in the release. "The ACT Engine has the potential to increase the amount of innovation coming into the ecosystem and the capabilities available to scale technologies needed in the energy transition. I am confident that the members of the ecosystem — incubators, accelerators, investors, universities, and corporates — are ready for the challenge that the ACT Engine will provide."

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This article originally ran on EnergyCapital.

City of Houston has entered into an agreement with Texas Southern University to develop an aviation program at the Houston Spaceport. Photo via fly2houston.com

Local university gets green light to launch new building at Houston Spaceport

cleared for takeoff

With a financial boost from the City of Houston, the aviation program at Texas Southern University will operate an aeronautical training hub on a two-acre site at Ellington Airport.

The Houston Airport System — which runs Ellington Airport, George Bush Intercontinental Airport, Hobby Airport, and Houston Spaceport — is chipping in as much as $5 billion to build the facility, which will train aeronautical professionals.

On May 3, the Houston City Council authorized a five-year agreement between the airport system and TSU to set up and operate the facility.

The facility will feature:

  • A 22,000-square-foot aircraft hangar
  • 20,000 square feet of aircraft apron
  • 7,200 square feet of office and training space
  • A 12,000-gallon, above-ground aviation fuel tank
  • Vehicle parking

Thanks to NASA and United Airlines, among other employers, Houston is home to more than 500 aviation and aerospace companies. Over 23,000 people in the Houston area work in the aviation and aerospace sector.

“The air transportation industry in Houston and across the United States is growing and provides career opportunities for those with the skills needed to succeed,” Houston Mayor Sylvester Turner says in a news release.

Mario Diaz, director of aviation for Houston’s airports, says the new training center will “invest in and inspire the next generation of aviation professionals.”

“The facility at Ellington Airport continues the illustrious story of Houston’s aeronautical history. … Soon, students at Texas Southern University will apply the crucial lessons learned at Ellington Airport to revolutionize the aviation industry,” says Diaz.

Terence Fontaine, executive director of aviation at TSU, says the facility will house his program’s eight aircraft. It also will provide “an enhanced environment for student learning opportunities as we work to address our nation’s critical aviation needs,” says Fontaine.

TSU’s College of Science, Engineering & Technology offers a bachelor’s degree in aviation science management for students pursuing careers at airports, airlines, air traffic control centers, and other employers in the aviation sector. More than 100 students are enrolled in the program.

In January, United CEO Scott Kirby warned that due to shortages of pilots and other airline workers, plans to bulk up capacity in 2023 and beyond “are simply unachievable.”

He noted that United, American Airlines, Delta Air Lines, and Southwest Airlines alone intend to hire about 8,000 pilots this year, compared with a historical range of 6,000 to 7,000 pilots per year.

“We believe any airline that tries to run at the same staffing levels that it had pre-pandemic is bound to fail,” Kirby said on a United earnings call, “and likely to tip over to meltdown anytime there are weather or air traffic control stresses in the system.”

Houston serves as one of United’s hubs. The local hub employs more than 12,000 people. On May 4, the airline held a career fair aimed at filling jobs at George Bush Intercontinental. United plans to add 3,000 employees in Houston by 2026.

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New Rice Brain Institute partners with TMC to award inaugural grants

brain trust

The recently founded Rice Brain Institute has named the first four projects to receive research awards through the Rice and TMC Neuro Collaboration Seed Grant Program.

The new grant program brings together Rice faculty with clinicians and scientists at The University of Texas Medical Branch, Baylor College of Medicine, UTHealth Houston and The University of Texas MD Anderson Cancer Center. The program will support pilot projects that address neurological disease, mental health and brain injury.

The first round of awards was selected from a competitive pool of 40 proposals, and will support projects that reflect Rice Brain Institute’s research agenda.

“These awards are meant to help teams test bold ideas and build the collaborations needed to sustain long-term research programs in brain health,” Behnaam Aazhang, Rice Brain Institute director and co-director of the Rice Neuroengineering Initiative, said in a news release.

The seed funding has been awarded to the following principal investigators:

  • Kevin McHugh, associate professor of bioengineering and chemistry at Rice, and Peter Kan, professor and chair of neurosurgery at the UTMB. McHugh and Kan are developing an injectable material designed to seal off fragile, abnormal blood vessels that can cause life-threatening bleeding in the brain.
  • Jerzy Szablowski, assistant professor of bioengineering at Rice, and Jochen Meyer, assistant professor of neurology at Baylor. Szablowski and Meyer are leading a nonsurgical, ultrasound approach to deliver gene-based therapies to deep brain regions involved in seizures to control epilepsy without implanted electrodes or invasive procedures.
  • Juliane Sempionatto, assistant professor of electrical and computer engineering at Rice, and Aaron Gusdon, associate professor of neurosurgery at UTHealth Houston. Sempionatto and Gusdon are leading efforts to create a blood test that can identify patients at high risk for delayed brain injury following aneurysm-related hemorrhage, which could lead to earlier intervention and improved outcomes.
  • Christina Tringides, assistant professor of materials science and nanoengineering at Rice, and Sujit Prabhu, professor of neurosurgery at MD Anderson, who are working to reduce the risk of long-term speech and language impairment during brain tumor removal by combining advanced brain recordings, imaging and noninvasive stimulation.

The grants were facilitated by Rice’s Educational and Research Initiatives for Collaborative Health (ENRICH) Office. Rice says that the unique split-funding model of these grants could help structure future collaborations between the university and the TMC.

The Rice Brain Institute launched this fall and aims to use engineering, natural sciences and social sciences to research the brain and reduce the burden of neurodegenerative, neurodevelopmental and mental health disorders. Last month, the university's Shepherd School of Music also launched the Music, Mind and Body Lab, an interdisciplinary hub that brings artists and scientists together to study the "intersection of the arts, neuroscience and the medical humanities." Read more here.

Your data center is either closer than you think or much farther away

houston voices

A new study shows why some facilities cluster in cities for speed and access, while others move to rural regions in search of scale and lower costs. Based on research by Tommy Pan Fang (Rice Business) and Shane Greenstein (Harvard).

Key findings:

  • Third-party colocation centers are physical facilities in close proximity to firms that use them, while cloud providers operate large data centers from a distance and sell access to virtualized computing resources as on‑demand services over the internet.
  • Hospitals and financial firms often require urban third-party centers for low latency and regulatory compliance, while batch processing and many AI workloads can operate more efficiently from lower-cost cloud hubs.
  • For policymakers trying to attract data centers, access to reliable power, water and high-capacity internet matter more than tax incentives.

Recent outages and the surge in AI-driven computing have made data center siting decisions more consequential than ever, especially as energy and water constraints tighten. Communities invest public dollars on the promise of jobs and growth, while firms weigh long-term commitments to land, power and connectivity.

Against that backdrop, a critical question comes into focus: Where do data centers get built — and what actually drives those decisions?

A new study by Tommy Pan Fang (Rice Business) and Shane Greenstein (Harvard Business School) provides the first large-scale statistical analysis of data center location strategies across the United States. It offers policymakers and firms a clearer starting point for understanding how different types of data centers respond to economic and strategic incentives.

Forthcoming in the journal Strategy Science, the study examines two major types of infrastructure: third-party colocation centers that lease server space to multiple firms, and hyperscale cloud centers owned by providers like Amazon, Google and Microsoft.

Two Models, Two Location Strategies

The study draws on pre-pandemic data from 2018 and 2019, a period of relative geographic stability in supply and demand. This window gives researchers a clean baseline before remote work, AI demand and new infrastructure pressures began reshaping internet traffic patterns.

The findings show that data centers follow a bifurcated geography. Third-party centers cluster in dense urban markets, where buyers prioritize proximity to customers despite higher land and operating costs. Cloud providers, by contrast, concentrate massive sites in a small number of lower-density regions, where electricity, land and construction are cheaper and economies of scale are easier to achieve.

Third-party data centers, in other words, follow demand. They locate in urban markets where firms in finance, healthcare and IT value low latency, secure storage, and compliance with regulatory standards.

Using county-level data, the researchers modeled how population density, industry mix and operating costs predict where new centers enter. Every U.S. metro with more than 700,000 residents had at least one third-party provider, while many mid-sized cities had none.

ImageThis pattern challenges common assumptions. Third-party facilities are more distributed across urban America than prevailing narratives suggest.

Customer proximity matters because some sectors cannot absorb delay. In critical operations, even slight pauses can have real consequences. For hospital systems, lag can affect performance and risk exposure. And in high-frequency trading, milliseconds can determine whether value is captured or lost in a transaction.

“For industries where speed is everything, being too far from the physical infrastructure can meaningfully affect performance and risk,” Pan Fang says. “Proximity isn’t optional for sectors that can’t absorb delay.”

The Economics of Distance

For cloud providers, the picture looks very different. Their decisions follow a logic shaped primarily by cost and scale. Because cloud services can be delivered from afar, firms tend to build enormous sites in low-density regions where power is cheap and land is abundant.

These facilities can draw hundreds of megawatts of electricity and operate with far fewer employees than urban centers. “The cloud can serve almost anywhere,” Pan Fang says, “so location is a question of cost before geography.”

The study finds that cloud infrastructure clusters around network backbones and energy economics, not talent pools. Well-known hubs like Ashburn, Virginia — often called “Data Center Alley” — reflect this logic, having benefited from early network infrastructure that made them natural convergence points for digital traffic.

Local governments often try to lure data centers with tax incentives, betting they will create high-tech jobs. But the study suggests other factors matter more to cloud providers, including construction costs, network connectivity and access to reliable, affordable electricity.

When cloud centers need a local presence, distance can sometimes become a constraint. Providers often address this by working alongside third-party operators. “Third-party centers can complement cloud firms when they need a foothold closer to customers,” Pan Fang says.

That hybrid pattern — massive regional hubs complementing strategic colocation — may define the next phase of data center growth.

Looking ahead, shifts in remote work, climate resilience, energy prices and AI-driven computing may reshape where new facilities go. Some workloads may move closer to users, while others may consolidate into large rural hubs. Emerging data-sovereignty rules could also redirect investment beyond the United States.

“The cloud feels weightless,” Pan Fang says, “but it rests on real choices about land, power and proximity.”

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This article originally appeared on Rice Business Wisdom. Written by Scott Pett.

Pan Fang and Greenstein (2025). “Where the Cloud Rests: The Economic Geography of Data Centers,” forthcoming in Strategy Science.

Houston climbs to top 10 spot on North American tech hubs index

tech report

Houston already is the Energy Capital of the World, and now it’s gaining ground as a tech hub.

On Site Selection magazine’s 2026 North American Tech Hub Index, Houston jumped to No. 10 from No. 16 last year. The index relies on data from Site Selection as well as data from CBRE, CompTIA and TeleGeography to rank the continent’s tech hotspots. The index incorporates factors such as internet connectivity, tech talent and facility projects for tech companies.

In 2023, the Greater Houston Partnership noted the region had “begun to receive its due as a prominent emerging tech hub, joining the likes of San Francisco and Austin as a major player in the sector, and as a center of activity for the next generation of innovators and entrepreneurs.”

The Houston-area tech sector employs more than 230,000 people, according to the partnership, and generates an economic impact of $21.2 billion.

Elsewhere in Texas, two other metros fared well on the Site Selection index:

  • Dallas-Fort Worth nabbed the No. 1 spot, up from No. 2 last year.
  • Austin rose from No. 8 last year to No. 7 this year.

San Antonio slid from No. 18 in 2025 to No. 22 in 2026, however.

Two economic development officials in DFW chimed in about the region’s No. 1 ranking on the index:

  • “This ranking affirms what we’ve long seen on the ground — Dallas-Fort Worth is a top-tier technology and innovation center,” said Duane Dankesreiter, senior vice president of research and innovation at the Dallas Regional Chamber. “Our region’s scale, talent base, and diverse strengths … continue to set DFW apart as a national leader.”
  • “Being recognized as the top North American tech hub underscores the strength of the entire Dallas-Fort Worth region as a center of innovation and next-generation technology,” said Robert Allen, president and CEO of the Fort Worth Economic Development Partnership.

While not directly addressing Austin’s Site Selection ranking, Thom Singer, CEO of the Austin Technology Council, recently pondered whether Silicon Hills will grow “into the kind of community that other cities study for the right reasons.”

“Austin tech is not a club. It is not a scene. It is not a hashtag, a happy hour, or any one place or person,” Singer wrote on the council’s blog. “Austin tech is an economic engine and a global brand, built by thousands of people who decided to take a risk, build something, hire others, and be part of a community that is still young enough to reinvent itself.”

South of Austin, Port San Antonio is driving much of that region’s tech activity. Occupied by more than 80 employers, the 1,900-acre tech and innovation campus was home to 18,400 workers in 2024 and created a local economic impact of $7.9 billion, according to a study by Zenith Economics.

“Port San Antonio is a prime example of how innovation and infrastructure come together to strengthen [Texas’] economy, support thousands of good jobs, and keep Texas competitive on the global stage,” said Kelly Hancock, the acting state comptroller.