CPRIT grants $22M to bring top cancer researchers to Houston

fresh funding

CPRIT recently granted $93 million to 61 organizations and scientists, including many in Houston, to advance cancer research. Carter Smith/Courtesy of MD Anderson

Several prominent cancer researchers are coming to the Houston area thanks to $22 million in grants recently awarded by the Cancer Prevention and Research Institute of Texas (CPRIT).

The biggest CPRIT recruitment grant — $6 million — went to genetics researcher Jean Gautier. Gautier, a professor of genetics and development at Columbia University’s Institute for Cancer Genetics, is joining the University of Texas MD Anderson Cancer Center to continue his research.

The website for Gautier’s lab at Columbia provides this explanation of his research:

“The main objective of our research is to better understand the molecular mechanisms responsible for the maintenance of genome stability. These controls are lost in cancer, which is characterized by genomic instability.”

Aside from his work as a professor, Gautier is co-leader of the Herbert Irving Comprehensive Cancer Center’s Cancer Genomics and Epigenomics Program at Columbia.

Other recipients of CPRIT recruitment grants include:

$2 million to recruit Xun Sun from the Scripps Research Institute to the University of Texas Medical Branch at Galveston.
$2 million to recruit Mingqi Han from the University of California, Los Angeles to MD Anderson.
$2 million to recruit Matthew Jones from Stanford University to MD Anderson.
$2 million to recruit Linna An from the University of Washington to Rice University.
$2 million to recruit Alissa Greenwald from the Weizmann Institute of Science to MD Anderson.
$2 million to recruit Niladri Sinha from Johns Hopkins University to the Baylor College of Medicine.
$2 million for Luigi Perelli to stay at MD Anderson so he can be put on a tenure track and set up a research lab.
$2 million for Benjamin Schrank to stay at MD Anderson so he can be put on a tenure track and set up a research lab.

Over $20.2 million in academic research grants were awarded to researchers at:

Baylor College of Medicine
Houston Methodist Research Institute
Rice University
Texas Southern University
University of Houston
University of Texas Health Science Center at Houston
University of Texas MD Anderson Cancer Center
University of Texas Medical Branch at Galveston

In addition, nearly $4.45 million in cancer prevention grants were awarded to one researcher at the University of Texas Medical Branch at Galveston and another at Texas Southern University.

Also, five Houston businesses benefited from CPRIT grants for product development research:

Allterum Therapeutics, $2,999,996
CTMC, $1,342,178
Instapath, $900,000
Prana Surgical, $900,000
InformAI, $465,188

“Texas is a national leader in the fight against cancer,” said Kristen Pauling Doyle, CPRIT’s CEO. “We can measure the return on investment from CPRIT grants … not only in the economic benefits flowing from increased financial activity and jobs in the state, but more importantly in the cancers avoided, detected early, and treated successfully. Thanks to the Legislature’s vision, this commitment is saving lives.”

Overall, CPRIT approved 61 grants totaling more than $93 million in this recent round of funding.

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The next phase of the Houston Spaceport will build out connectivity and workforce training. Rendering via Houston Airports

Houston Spaceport takes off with second phase of development

ready for liftoff

Since the Houston Spaceport secured the 10th FAA-Licensed commercial spaceport designation in 2015, the development's tenants have gone on to secure billions in NASA contracts. Now, the Houston Spaceport is on to its next phase of growth.

“Reflecting on its meteoric rise, the Spaceport has seen remarkable growth in a short span of time. From concepts on paper to the opening of Axiom Space, Collins Aerospace, and Intuitive Machines, the journey has been nothing short of extraordinary,” says Arturo Machuca, director of Ellington Airport and the Houston Spaceport, in a news release. “These anchor tenants, collectively holding about $5 billion in contracts with NASA and other notable aerospace companies, are not just shaping the future of space exploration but injecting vitality into Houston’s economy.”

The next phase of development, according to Houston Airports, will include:

The construction of a taxiway to connect Ellington Airport and the Spaceport
The construction of a roadway linking Phase 1 infrastructure to Highway 3
The expansion of the EDGE Center, in partnership with San Jacinto College

Rendering via Houston Airports

The Houston Spaceport's first phase completed in 2019. Over the past few years, tenants delivered on their own buildouts. Last year, Intuitive Machines moved into its new $40 million headquarters and Axiom Space opened its test facility. In 2022, Collins Aerospace cut the ribbon on its new 120,000 square-foot facility.

“The vision for the Houston Spaceport has always been ambitious,” says Jim Szczesniak, director of Aviation for Houston Airports. “Our vision is to create a hub for aviation and aerospace enterprises that will shape the future of commercial spaceflight.”

Educational partners have also revealed new spaces, including San Jacinto College's EDGE Center, which broke ground in July of 2019, finally celebrated its grand opening in 2021. Last year, Texas Southern University got the greenlight to operate an aeronautical training hub on a two-acre site at Ellington Airport.

“By providing the education and training needed to sustain jobs in the rapidly evolving space industry, the Spaceport is not only attracting companies but also nurturing the talent that will drive Houston's aerospace sector forward,” continues Szczesniak in the release.

Texas Southern University got the greenlight for funding for its flight academy. Photo courtesy of Houston Airport System

City approves $5.5M investment for Houston flight school

greenlight

Houston City Council approved Houston Airports to use $5.5 million from its Airport Improvement Fund to build the Texas Southern University Flight Academy at Ellington Airport.

The new facility will add to student learning with TSU’s aviation program and internships. Construction will begin in May of 2024 with an expected completion of May 2025.

“The investment in this facility allows Houston to remain at the forefront of supporting the rapid growth of the air transportation industry in the United States,” Mayor Sylvester Turner says in a news release. “I am honored that the City of Houston is taking the initiative to build this facility, which will provide numerous opportunities for Houstonians in the future."

TSU expanded its flight training fleet at Ellington Airport with the addition of a new Cessna 172, which brings the university to nine aircrafts that are available to help expand the program.TSU also has a virtual airport laboratory that trains pilots, air traffic controllers, and airport officers.

Construction is expected to begin in May of 2024 with an anticipated completion of May 2025. Rendering courtesy of Houston Airport Systen

The facility will be two acres and built on land accessible to an existing taxi-lane connection. The facility includes a 24,000 square foot aircraft hangar, an 11,000 square feet of aircraft apron, a 4,200 square feet of office/training/classroom space, an 8,000 gallon above-ground aviation fuel tank, and vehicle parking.

“This new facility is a major step toward Texas Southern University becoming the premier destination for training pilots and aviation professionals of the future,” TSU Interim President Mary Evans Sias says in a news release. “Our aviation program has reached heights in achievement that are unprecedented for the state of Texas. We look forward to the future aviators who will come through these doors and leave prepared to seize the opportunities in aviation, which we know are only increasing. We are deeply appreciative of the City of Houston for making this investment into TSU, and we know the return on this investment will be worthwhile.”

The Houston City Council approved a memorandum of agreement this past May for five years between Houston Airports and TSU.

“Houston Airports is a proud partner of TSU as it educates and inspires the next generation of pilots, mechanics and air traffic controllers,” Mario Diaz, director of Aviation for Houston Airports, says in a news release. “From training pilots during World War 1, and NASA astronauts as they prepared to step on the moon, to now training the next generation of aviation professionals, Ellington Airport continues to play a crucial role in Houston’s aviation history.”

Here's what Houston tech and startup news trended this year on InnovationMap in space tech. Image via Getty Images

Top Space City news of 2023: New Houston unicorn, an IPO, spaceport development, and more

year in review

Editor's note: As the year comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. In the Space City, there were dozens of space tech stories, from a space tech company reaching unicorn status to another completing its IPO. Here are five Houston space tech-focused articles that stood out to readers this year — be sure to click through to read the full story.

Local university gets green light to launch new building at Houston Spaceport

City of Houston has entered into an agreement with Texas Southern University to develop an aviation program at the Houston Spaceport. Photo via fly2houston.com

With a financial boost from the City of Houston, the aviation program at Texas Southern University will operate an aeronautical training hub on a two-acre site at Ellington Airport.

The Houston Airport System — which runs Ellington Airport, George Bush Intercontinental Airport, Hobby Airport, and Houston Spaceport — is chipping in as much as $5 billion to build the facility, which will train aeronautical professionals.

On May 3, the Houston City Council authorized a five-year agreement between the airport system and TSU to set up and operate the facility. Continue reading the full story from May.

Houston space tech startup closes deal to IPO

Intuitive Machines will be listed on Nasdaq beginning February 14. Photo via intuitivemachines.com

It's official. This Houston company is live in the public market.

Intuitive Machines, a space tech company based in Southeast Houston, announced that it has completed the transaction to merge with Inflection Point Acquisition Corp., a special purpose acquisition company traded on Nasdaq.

“We are excited to begin this new chapter as a publicly traded company,” says Steve Altemus, co-founder, president, and CEO of Intuitive Machines, in a news release. “Intuitive Machines is in a leading position to replace footprints with a foothold in the development of lunar space. With our launch into the public sphere through Inflection Point, we have reached new heights financially and opened the doors for even greater exploration and innovation for the progress of humanity.”

The transaction, which was originally announced in September, was approved by Inflection Point’s shareholders in a general meeting on February 8. As a result of the deal, the company will receive around $55 million of committed capital from an affiliate of its sponsor and company founders, the release states. Continue reading the full story from February.

Houston to host 6 Italian aerospace companies with new program

Six Italian companies are coming to the Space City to accelerate their businesses thanks to a new program. Photo via nasa.gov

It's an Italian invasion in Houston — and it's happening in the name of accelerating innovation within aerospace.

For the first time, Italy has announced an international aerospace-focused program in the United States. The Italian Trade Agency and Italian Space Agency will partner with Space Foundation to launch Space It Up, an initiative that will accelerate six companies in Houston.

“The launch of Space It Up marks a pivotal moment in our ongoing commitment to nurturing innovation and facilitating global partnerships," Fabrizio Giustarini, Italian Trade Commissioner of Houston, says in a news release. "This program serves as a testament to the collaborative spirit that defines the aerospace industry. It represents the convergence of Italian ingenuity and Houston's esteemed legacy in space exploration, setting the stage for unprecedented advancements." Continue reading the full story from August.

Houston space tech startup raises $350M series C, clinches unicorn status

Axiom Space CEO Michael Suffredini (right) has announced the company's series C round with support from Aljazira Capital, led by CEO Naif AlMesned. Photo courtesy of Axiom Space

Houston has another unicorn — a company valued at $1 billion or more — thanks to a recent round of funding.

Axiom Space released the news this week that it's closed its series C round of funding to the tune of $350 million. While the company didn't release its valuation, it confirmed to Bloomberg that it's over the $1 billion threshold. Axiom reports that, according to available data, it's now raised the second-most funding of any private space company in 2023 behind SpaceX.

Saudi Arabia-based Aljazira Capital and South Korea-based Boryung Co. led the round. To date, Axiom has raised over $505 million with $2.2 billion in customer contracts, according to the company.

“We are honored to team with investors like Aljazira Capital, Boryung and others, who are committed to realizing the Axiom Space vision,” Axiom Space CEO and president Michael Suffredini says in a news release. “Together, we are working to serve innovators in medicine, materials science, and on-orbit infrastructure who represent billions of dollars in demand over the coming decade. Continue reading the full story from August.

Texas university to build $200M space institute in Houston

Texas A&M University will build a new facility near NASA's Johnson Space Center. Photo courtesy of JSC

Texas A&M University's board of regents voted to approve the construction of a new institute in Houston that hopes to contribute to maintaining the state's leadership within the aerospace sector.

This week, the Texas A&M Space Institute got the greenlight for its $200 million plan. The announcement follows a $350 million investment from the Texas Legislature. The institute is planned to be constructed next to NASA’s Johnson Space Center in Houston.

“The Texas A&M Space Institute will make sure the state expands its role as a leader in the new space economy,” John Sharp, chancellor of the Texas A&M System, says in a news release. “No university is better equipped for aeronautics and space projects than Texas A&M.” Continue reading the full story from August.

Houston is in the running to receive millions from a program from the National Science Foundation. Photo via Getty Images

Houston named semifinalist for major energy transition funding opportunity

making moves

The National Science Foundation announced 34 semifinalists for a regional innovation program that will deploy up to $160 million in federal funding over the next 10 years. Among the list of potential regions to receive this influx of capital is Houston.

The Greater Houston Partnership and the Houston Energy Transition Initiative developed the application for the NSF Regional Innovation Engine competition in collaboration with economic, civic, and educational leaders from across the city and five regional universities, including the University of Houston, The University of Texas at Austin, Texas Southern University, Rice University, and Texas A&M University.

The proposed project for Houston — called the Accelerating Carbon-Neutral Technologies and Policies for Energy Transition, or ACT, Engine — emphasizes developing sustainable and equitable opportunities for innovators and entrepreneurs while also pursuing sustainable and equitable energy access for all.

“The ACT Engine will leverage our diverse energy innovation ecosystem and talent, creating a true competitive advantage for existing and new energy companies across our region," says Jane Stricker, senior vice president of energy transition and executive director for HETI, in a statement. "Texas is leading the way in nearly every energy and energy transition solution, and this Engine can catalyze our region’s continued growth in low-carbon technology development and deployment."

If Houston's proposal is selected as a finalist, it could receive up to $160 million over 10 years. The final list of NSF Engines awards is expected this fall, and, according to a release, each awardee will initially receiving about $15 million for the first two years.

"Each of these NSF Engines semifinalists represents an emerging hub of innovation and lends their talents and resources to form the fabric of NSF's vision to create opportunities everywhere and enable innovation anywhere," NSF Director Sethuraman Panchanathan says in a news release. "These teams will spring ideas, talent, pathways and resources to create vibrant innovation ecosystems all across our nation."

The NSF selected its 34 semifinalists from 188 original applicants, and the next step for Houston is a virtual site visit that will assess competitive advantages, budget and resource plans for R&D and workforce development, and the proposed leadership’s ability to mobilize plans into action over the first two years.

"Houston is poised, like no other city, to lead the energy transition. The ACT Engine presents a remarkable opportunity to not only leverage the region's unparalleled energy resources and expertise but also harness our can-do spirit. Houston has a proven track record of embracing challenges and finding innovative solutions,” says Renu Khator, president of the University of Houston, in the statement. “Through the collaborative efforts facilitated by the ACT Engine, I am confident that we can make significant strides towards creating a sustainable future that harmonizes economic growth, environmental protection and social equity."

NSF Engines will announce awards this fall after a round of in-person interviews of finalists named in July. With Houston's track record for building thriving industry hubs in energy, health care, aerospace, and the culinary arts, the region is eager to establish the next generation of leaders and dreamers responding to some of the greatest economic and societal challenges ever seen in America.

“Our energy innovation ecosystem is inclusive, dynamic, and fast growing," says Barbara Burger, energy transition adviser and former Chevron executive, in the release. "The ACT Engine has the potential to increase the amount of innovation coming into the ecosystem and the capabilities available to scale technologies needed in the energy transition. I am confident that the members of the ecosystem — incubators, accelerators, investors, universities, and corporates — are ready for the challenge that the ACT Engine will provide."

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This article originally ran on EnergyCapital.

City of Houston has entered into an agreement with Texas Southern University to develop an aviation program at the Houston Spaceport. Photo via fly2houston.com

Local university gets green light to launch new building at Houston Spaceport

cleared for takeoff

With a financial boost from the City of Houston, the aviation program at Texas Southern University will operate an aeronautical training hub on a two-acre site at Ellington Airport.

On May 3, the Houston City Council authorized a five-year agreement between the airport system and TSU to set up and operate the facility.

The facility will feature:

A 22,000-square-foot aircraft hangar
20,000 square feet of aircraft apron
7,200 square feet of office and training space
A 12,000-gallon, above-ground aviation fuel tank
Vehicle parking

Thanks to NASA and United Airlines, among other employers, Houston is home to more than 500 aviation and aerospace companies. Over 23,000 people in the Houston area work in the aviation and aerospace sector.

“The air transportation industry in Houston and across the United States is growing and provides career opportunities for those with the skills needed to succeed,” Houston Mayor Sylvester Turner says in a news release.

Mario Diaz, director of aviation for Houston’s airports, says the new training center will “invest in and inspire the next generation of aviation professionals.”

“The facility at Ellington Airport continues the illustrious story of Houston’s aeronautical history. … Soon, students at Texas Southern University will apply the crucial lessons learned at Ellington Airport to revolutionize the aviation industry,” says Diaz.

Terence Fontaine, executive director of aviation at TSU, says the facility will house his program’s eight aircraft. It also will provide “an enhanced environment for student learning opportunities as we work to address our nation’s critical aviation needs,” says Fontaine.

TSU’s College of Science, Engineering & Technology offers a bachelor’s degree in aviation science management for students pursuing careers at airports, airlines, air traffic control centers, and other employers in the aviation sector. More than 100 students are enrolled in the program.

In January, United CEO Scott Kirby warned that due to shortages of pilots and other airline workers, plans to bulk up capacity in 2023 and beyond “are simply unachievable.”

He noted that United, American Airlines, Delta Air Lines, and Southwest Airlines alone intend to hire about 8,000 pilots this year, compared with a historical range of 6,000 to 7,000 pilots per year.

“We believe any airline that tries to run at the same staffing levels that it had pre-pandemic is bound to fail,” Kirby said on a United earnings call, “and likely to tip over to meltdown anytime there are weather or air traffic control stresses in the system.”

Houston serves as one of United’s hubs. The local hub employs more than 12,000 people. On May 4, the airline held a career fair aimed at filling jobs at George Bush Intercontinental. United plans to add 3,000 employees in Houston by 2026.

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5+ must-know application deadlines for Houston innovators

apply now

Editor's note: As 2026 ramps up, the Houston innovation scene is looking for the latest groups of innovative startups that'll make an impact. A number of accelerators and competitions have opened applications. Read below to see which might be a good fit for you or your venture. And take careful note of the deadlines. Please note: this article may be updated to include additional information and programs.

Did we miss an accelerator or competition accepting applications? Email innoeditor@innovationmap.com for editorial consideration.

2026 HCC Business Plan Competition

Deadline: Jan. 26

Details: HCC’s annual Business Plan Competition (BPC) is an opportunity for proposed, startup and existing entrepreneurs to develop focused plans to start or grow their businesses. Accepted teams will be announced and training will begin in late February and run through early June, with six free, three-hour training sessions. Advising will be provided to each accepted team. Applicants can apply as a team of up to five persons. Finalists will present to to gudges on May 27, 2026. Last year, $26,000 was awarded in seed money to the top five teams. In-kind prizes were also awarded to all graduating teams including free products, services and memberships, with an estimated in-kind value totaling $147,000. Find more information here.

University of Houston Technology Bridge Innov8 Hub (Spring 2026)

Deadline: Jan . 30

Details: UHTB Innov8 Hub’s immersive, 12-week startup acceleration program designed to help early-stage founders launch and scale their technology startups. Selected participants will gain access to expert mentors and advisors, collaborate with a cohort of peers, and compete for cash prizes during our final pitch event. The cohort begins Feb. 16, 2026. The program culminates in Pitch Day, where participants present their ventures to an audience of investors and partners from across the UH innovation ecosystem. Find more information here.

Rice Business Plan Competition 2026

Deadline: Jan. 31

Details: The Rice Business Plan Competition, hosted by the Rice Alliance for Technology and Entrepreneurship, gives collegiate entrepreneurs real-world experience to pitch their startups, enhance their business strategy and learn what it takes to launch a successful company. Forty-two teams will compete for more than $1 million in cash, investments and prizes on April 9-11, 2026. Find more information here.

Rice Veterans Business Battle 2026

Deadline: Jan. 31

Details: The Rice Veterans Business Battle is one of the nation’s largest pitch competitions for veteran-led startups, providing founders with mentorship, exposure to investors and the opportunity to compete for non-dilutive cash prizes. The event has led to more than $10 million of investments since it began in 2015. Teams will compete April 8-9, 2026. Find more information here.

TEX-E Fellows Application 2026-2027

Deadline: Feb. 10

Details: The TEX‑E Fellowship is a hands-on program designed for students interested in energy, climate, and entrepreneurship across Texas. It connects participants with industry mentors, startup founders, investors and academic leaders while providing practical, "real-world" experience in customer discovery, business modeling, and energy-transition innovation. Fellows gain access to workshops, real-world projects, and a statewide network shaping the future of energy and climate solutions. Participants must be a student at PVAMU, UH, UT Austin, Rice University, MIT or Texas A&M. Find more information here.

Greentown Go Make 2026

Deadline: March 10

Details: Greentown Go Make 2026 is an open-innovation program with Shell and Technip Energies. The six-month program is advancing industrial decarbonization by accelerating catalytic innovations. Selected startups will gain access to a structured platform to engage leadership from Shell and Technip Energies and explore potential partnership outcomes, including pilots and demonstrations. They’ll also receive networking opportunities, partnership-focused programming, and marketing visibility throughout the program. The cohort will be selected in May. Find more information here.

Houston startups closed $1.75 billion in 2025 VC funding, says report

by the numbers

Going against national trends, Houston-area startups raised 7 percent less venture capital last year than they did in 2024, according to the new PitchBook-NVCA Venture Monitor report.

The report shows local startups collected $1.75 billion in venture capital in 2025, down from $1.89 billion the previous year.

Houston-based geothermal energy company Fervo Energy received a big chunk of the region’s VC funding last year. Altogether, the startup snagged $562 million in investments, as well as a $60 million extension of an existing loan and $45.6 million in debt financing. The bulk of the 2025 haul was a $462 million Series E round.

In the fourth quarter of last year, Houston-area VC funding totaled $627.68 million. That was a 22 percent drop from $765.03 million during the same period in 2024. Still, the Q4 total was the biggest quarterly total in 2025.

Across the country, startups picked up $339.4 trillion in VC funding last year, a 59 percent increase from $213.2 trillion in 2024, according to the report. Over the last 10 years, only the VC total in 2021 ($358.2 trillion) surpassed the total from 2025.

Nationwide, startups in the artificial intelligence and machine learning sector accounted for the biggest share of VC funding (65.4 percent) in 2025, followed by software-as-a-service (SaaS), big data, manufacturing, life sciences and healthtech, according to the report.

“Despite an overall lack of new fundraising and a liquidity market that did not shape up as hoped in 2025, deal activity has begun a phase of regrowth, with deal count estimates showing increases at each stage, and deal value, though concentrated in a small number of deals, falling just [8 percent] short of the 2021 figure,” the report reads.

Sandbox VR brings new gaming center to Houston's tech-savvy population

Get In The Game

Sandbox VR, a futuristic, full-body virtual reality gaming experience, has announced it will enter the Houston market this month, opening its first local gaming center on January 23.

"Houston's reputation as a hub for innovation and technology makes it a perfect fit for Sandbox VR," said Steve Zhao, CEO and founder of Sandbox VR, in a statement. "The city's diverse, tech-savvy population and strong entertainment culture create an ideal environment for our immersive VR experiences. LOL Entertainment continues to exceed our expectations as a partner, and we're excited to bring our cutting-edge virtual reality gaming to Texas's largest city."

The new gaming center opens Friday, January 23 at 797 Sorella Court in CityCentre.

One of the games that stands out is the Stranger Things: Catalyst game, based on the blockbuster Netflix television series. Groups of one to six players will be dropped into the sinister Hawkins Lab and the mysterious Upside Down to fight Demogorgons and other monsters. The game features Matthew Modine reprising his role as Dr. Martin "Papa" Brenner, who imbues players with psychic powers.

Other games include the supernatural pirate title The Curse of Davy Jones and other Netflix tie-ins based on Zack Snyder's Rebel Moon and Squid Game. Sandbox VR offers fully-immersive group play activities that range from combat to puzzle solving for a variety of age groups.

The opening of Sandbox VR is another part of the expansion of LOL Entertainment, who touts itself as one of the pre-eminent hosts of immersive and gaming experiences in the U.S. Sandbox VR will be their first entry into the Houston market, with another immersive group adventure game, Time Mission, set to open at the the Marq'E Entertainment District later this year.

“Bringing Sandbox VR to CityCentre Houston is a big milestone for LOL Entertainment, for Sandbox VR, and for this market,” said Rob Cooper, CEO of LOL Entertainment. “Houston is a fast-growing, experience-driven city, and we’re excited to give locals and visitors a truly immersive, social gaming destination that you can’t replicate anywhere.”

Presale tickets for the grand opening of Sandbox VR are available here. Standard pricing is $55-$65 per event, but Sandbox VR is running a special for 30 percent off with code OPEN30 for those who purchase before Thursday, January 22. Presale buyers are also entered into a drawing for free Sandbox VR for one year.

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This article originally appeared on CultureMap.com.

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