Houston pipeline heirs strike it rich as wealthiest family in Texas

AMERICA'S WEALTHIEST FAMILIES

Randa Williams is the high-profile heir of the Duncan family. Photo courtesy of Texas Monthly

Missouri has the Busches. Nebraska has the Buffetts. New York has the Hearsts. These are among the best-known wealthy families in the U.S.

Lesser-known nationally but well-known in Texas is the Duncan family of Houston, identified by FamilyMinded.com as the richest family in Texas. The website, which rounded up a list of the richest family in each state, pegs the family's estimated net worth at $26 billion; Forbes puts it at $25.6 billion.

The Duncan family comprises the four children of the late pipeline mogul Dan Duncan.

The children — Dannine Avara, Scott Duncan, Milane Frantz, and Randa Williams — inherited a tax-free $10 billion share of their father's estate following his death in 2010, when the so-called "death tax" had temporarily been repealed, according to Forbes. Each of them has an estimated net worth of $6.4 billion, Forbes says.

Williams is perhaps the most visible of the four Duncan heirs.

Williams is the only Duncan sibling who's involved in running the family business. She is chairwoman of Houston-based Enterprise Products Partners LP, the pipeline company that her father founded in 1968. Last year, the company posted revenue of $36.5 billion. In June, Williams made a big splash with her purchase of Austin-based Texas Monthly magazine.

While the Duncans are worth close to $26 billion, their wealth doesn't come close to that of Alice Walton of Fort Worth, the richest person in Texas. Forbes estimates her net worth at $52.4 billion.

FamilyMinded.com lists Alice Walton and her fellow heirs to the Walmart fortune as the richest family in Arkansas (where Walmart is based), with an estimated net worth of $163 billion. They're also the richest family in the U.S.

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This article originally ran on CultureMap.

Here's who you need to know this week in Houston innovation. Courtesy photos

3 Houston innovators to know this week

Who's who

This group of innovators to know this week are passionate people. From starting companies to making acquisitions, here's what they are up to and why you need to know their names.

Kelly McCormick, director of RED Labs

Photo courtesy of UH

Kelly McCormick is in the business of making University of Houston's entrepreneurs' dreams into realities. The RED Labs director wrote a guest article for InnovationMap about side hustles — what they are and how to make them worth their while.

"A side hustle has a science to it, and more importantly, it has an art," she writes. Read her full article here.

Randa Duncan Williams, chairman of Enterprise Products Partners LP

Photo courtesy of Texas Monthly

For the second time in three years, Texas Monthly has a new owner. But if Randa Duncan Williams — energy exec and heiress worth over $6 billion — has anything to say about it, she'll be the last new owner of the magazine. Duncan Williams — who acquired the magazine by way of a privately held company, Enterprise Products Company, that's a subsidiary of Enterprise Products Partners, the company her late father founded — says she wants to own the magazine "forever." Read the full story here.

Cody Gremminger, system engineer at Cyber One Solutions

Cody Gremminger

Photo courtesy of Cyber One Solutions

Cody Gremminger is running a booming tech services business with his fiance, Brian Carrico. The company is called Cyber One Solutions and provides management, service and IT support services to the greater Houston area with satellite offices in Austin, Dallas, Lufkin, Brenham, and Beaumont.

While business couldn't be better, the entrepreneur wants to make sure Houston takes this month to remember the losses and challenges that the LGBT community has endured to get where it is today. Read the full story here.

Texas Monthly has a new owner. Texas Monthly/Facebook

Houston billionaire energy exec buys Texas Monthly

Media on media

For the second time in less than three years, Texas Monthly has a new owner. Randa Duncan Williams, chairman of Houston-based midstream oil and gas company, Enterprise Products Partners LP, has purchased the Austin-based magazine. The terms of the sale were not disclosed.

The magazine will become a part of Enterprise Products Company (EPCO), "a privately held company which owns interests in commercial real estate and ranching, as well as a substantial interest in Enterprise Products Partners L.P., a publicly traded midstream energy company," says a release.

"I have been an avid Texas Monthly reader since I was a teenager," says Duncan Williams, chairman of Texas Monthly, LLC, and of EPCO, in the release. "My family is delighted to provide the resources to support this iconic Texas institution which is nationally recognized for its editorial flair."

Williams is the daughter of EPP's late founder, Dan L. Duncan. She has a net worth of $6.2 billion, according to Forbes.

In TM's official statement, president Scott Brown is quoted as saying Duncan Williams wants to own the magazine "forever."

Forever may be what the magazine needs, following a tumultuous era for Texas Monthly, considered to be both a beacon of Texas culture and a shining example of long-form magazine journalism. In 2016, it was purchased from Emmis Communications by Genesis Park, a private investment firm led by Paul Hobby of the famed Houston-based Hobby family. Following that purchase, Hobby took over the role of chairman and CEO of the magazine, launching an arguably rocky tenure for Texas Monthly.

In February 2017, Hobby announced that Tim Taliaferro would be taking over the editor in chief position from Brian Sweany, a longtime TM staffer who climbed the ladder from intern in 1996 to taking the editor position following Jake Silverstein's departure for The New York Times Magazine in 2014. About a dozen notable writers left after Sweany's departure, though it's unfair to say it was a result of the masthead shakeup.

Just a few weeks into the Hobby-Taliaferro regime, journalism watchdog Columbia Journalism Review reported that Texas Monthly, a 13-time National Magazine Award winner, was going in a lifestyle direction. Reader reaction — not to mention the response from the journalism world — was swift, forcing the magazine to backpedal.

A year later, the magazine faced another misstep, this one involving Bumble and an alleged pay-for-play on social media. The somewhat salacious story also broke in the Columbia Journalism Review and eventually led to Taliaferro being moved into the newly created role of chief innovation officer. Thus began a year-long search that ended with Dan Goodgame being named editor in January 2019.

It's not breaking news to say it's an uncertain time for journalism, and Texas Monthly has clearly not survived unscathed. But hopefully Duncan Williams' purchase will help move the "national magazine of Texas" into a new era, one with a clear and bold vision.

For the sake of one of the nation's best magazines, we hope so.

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This article originally ran on CultureMap.

Is Texas still full of wildcatters — but for tech and innovation? Some say yes, but with one caveat. Photo by Scott Halleran/Getty Images

Houston's innovation ecosystem channels the wildcatter's spirit — but with one major difference

Tech boom

Historically, Texas has been a land of opportunity, and that might ring true now more than ever since the state's oil boom. As Houston's innovation ecosystem grows and develops, are these entrepreneurs reminiscent of the wildcatter days of the early 1900s? Well, sort of.

"Wildcatting is supposed to be really wild. You're supposed to go out in the field and drill some holes and hope that you find something," says Marc Nathan, vice president of strategy at Egan Nelson in Austin. "Truth is, we're a lot more deliberate than that these days."

Wildcatting and deliberate innovation development were the topics of discussion at a panel in Austin during SXSW. The panel, which was hosted by Rice Business and Texas Monthly, was comprised of three panelists with Houston ties: Gabriella Rowe, CEO of Station Houston, Lawson Gow, CEO and founder of Houston-based The Cannon, and Nathan, who, though based in Austin now, was born and raised in Houston and has done business in town too.

Wildcatting new industries
All three panelists agreed that the entrepreneurial nature of the wildcatters is alive and well within Texas entrepreneurs, just now spread apart multiple industries. Among all of the major Texas cities — or DASH, as Nathan calls it, Dallas, Austin, San Antonio, and Houston — each has its specialty. Austin tends to specialize in consumer-facing technology, Dallas has a hold on B-to-B and transportation, and San Antonio has the military.

For Houston, which is most known for its energy, life sciences, and space technology, has some new territories it's growing in, says Rowe, from cybersecurity to sports technology. And all of these different industries seem to work together, which is encouraging to see for Rowe.

"That's the secret sauce that Houston has in many ways," Rowe says.

This ability to specialize is also what's also special about Houston. Rather than trying to compete with Austin and its consumer technology — Gow gave an example of a startup focusing on a doggy dating app — Houston is doing its own thing.

"What I love about Houston is we're trying to solve big problems," Gow, who is the son of InnovationMap's parent company's CEO, says. "We're not going to be the consumer software capital of the world and, for the most part, we're not going to mess around with doggy dating apps."

Houston's problems to overcome
One of the challenges Houston faces as an innovation ecosystem is access to funds. According to Nathan, putting money into tech is just not Houston investors are used to doing.

"Houstonians invest in the ground, with oil and gas, and on the ground, with real estate, but not in the cloud," Nathan says.

The reason being, Gow says, is investors tend to put money into industries they know, and there's a need for educating these investors in new industries.

"To compare to Austin, more people in Austin have tech startups that have been successful and they turn around and invest in what they know, which is tech startups," Gow says. "There's a generational effect."

Another challenge Houston faces is competition — but not with other Texas cities or the rest of the country. Competition between startups and accelerators for resources has the potential to hinder the city's growth as an ecosystem.

"We are fighting for very scarce resources — and it's not just money," Nathan says. "It's also talent."

Texas Monthly's chief innovation officer, Tim Taliaferro, moderated the panel. Natalie Harms/InnovationMap

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Rice team keeps CO2-to-fuel devices running 50 times longer in new study

Bubbling Up

In a new study published in the journal Science, a team of Rice University researchers shared findings on how acid bubbles can improve the stability of electrochemical devices that convert carbon dioxide into useful fuels and chemicals.

The team led by Rice associate professor Hoatian Wang addressed an issue in the performance and stability of CO2 reduction systems. The gas flow channels in the systems often clog due to salt buildup, reducing efficiency and causing the devices to fail prematurely after about 80 hours of operation.

“Salt precipitation blocks CO2 transport and floods the gas diffusion electrode, which leads to performance failure,” Wang said in a news release. “This typically happens within a few hundred hours, which is far from commercial viability.”

By using an acid-humidified CO2 technique, the team was able to extend the operational life of a CO2 reduction system more than 50-fold, demonstrating more than 4,500 hours of stable operation in a scaled-up reactor.

The Rice team made a simple swap with a significant impact. Instead of using water to humidify the CO2 gas input into the reactor, the team bubbled the gas through an acid solution such as hydrochloric, formic or acetic acid. This process made more soluble salt formations that did not crystallize or block the channels.

The process has major implications for an emerging green technology known as electrochemical CO2 reduction, or CO2RR, that transforms climate-warming CO2 into products like carbon monoxide, ethylene, or alcohols. The products can be further refined into fuels or feedstocks.

“Using the traditional method of water-humidified CO2 could lead to salt formation in the cathode gas flow channels,” Shaoyun Hao, postdoctoral research associate in chemical and biomolecular engineering at Rice and co-first author, explained in the news release. “We hypothesized — and confirmed — that acid vapor could dissolve the salt and convert the low solubility KHCO3 into salt with higher solubility, thus shifting the solubility balance just enough to avoid clogging without affecting catalyst performance.”

The Rice team believes the work can lead to more scalable CO2 electrolyzers, which is vital if the technology is to be deployed at industrial scales as part of carbon capture and utilization strategies. Since the approach itself is relatively simple, it could lead to a more cost-effective and efficient solution. It also worked well with multiple catalyst types, including zinc oxide, copper oxide and bismuth oxide, which are allo used to target different CO2RR products.

“Our method addresses a long-standing obstacle with a low-cost, easily implementable solution,” Ahmad Elgazzar, co-first author and graduate student in chemical and biomolecular engineering at Rice, added in the release. “It’s a step toward making carbon utilization technologies more commercially viable and more sustainable.”

A team led by Wang and in collaboration with researchers from the University of Houston also recently shared findings on salt precipitation buildup and CO2RR in a recent edition of the journal Nature Energy.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.