3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Tammi Wallace of the Greater Houston LGBT Chamber of Commerce, Adam Putterman of OURS, and Ghazal Qureshi of UpBrainery. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from edtech to mental health — recently making headlines in Houston innovation.

Tammi Wallace, co-founder of the Greater Houston LGBT Chamber of Commerce

Tammi Wallace of the Greater Houston LGBT Chamber of Commerce was a panelist on The Ion's Pride in Tech event. Photo via LinkedIn

There are a few days left in Pride Month, and Houston's tech community came together last week to celebrate — but also discuss some of the challenges within the ecosystem for LGBTQIA+ entrepreneurs.

In a Q&A with InnovationMap, Tammi Wallace, co-founder of the Houston LGBT Chamber of Commerce, shared her advice for LGBTQIA+ innovators and allies.

"Get involved with the Houston LGBT Chamber of Commerce," she says. "Since 2016, the chamber has been working to build a strong community to support LGBTQIA+ entrepreneurs and get them access to resources to help their businesses grow and thrive." Click here to read more.

Adam Putterman, co-founder of OURS

Adam Putterman, co-founder of OURS, shares how he jumped on the opportunity that is innovating the future of relationship health. Photo courtesy of OURS

More than ever before, people are warming up to the idea of seeking professional health care for more than just their bodies, Adam Putterman, co-founder of OURS says on the most recent episode of the Houston Innovators Podcast.

"We've seen a massive shift in the perception of counseling and therapy — and, more importantly, all the aspects of health that are not just your body," he explains. "It's no longer just going to the gym, it's meditating, coaching for a professional field. We've found that people are taking that mindset and applying it to their relationship as well."

After launching its beta in 2020, OURS worked in stealth to develop its product, which officially launched in May. The platform costs $400 for a four-week program that includes six personalized interactive sessions with an OURS guide at the helm of the experience. These one-hour technology-powered sessions are based around an innovative new technology, called Loveware, and include dynamic and meaningful conversations between a couple that are built around the magic that comes from being in the room with an expert. Click here to listen to the full episode and read more.

Ghazal Qureshi, founder and CEO of UpBrainery

Innovations like artificial intelligence, augmented reality, and machine learning certainly have advantages in the edtech sector. Photo courtesy

The education community is facing big changes thanks to technology and new innovations. In a guest column for InnovationMap, Ghazal Qureshi — founder and CEO of UpBrainery, a Houston-based immersive educational technology platform — shares how things like artificial intelligence, machine learning, and more have the potential to impact the sector.

"AI has created benefits for educators as well, such as it has created a task automation system in which all kinds of daily mundane tasks including grading papers, admin work, replying to queries, etc. have been directly automated," she writes. "Although adopting cutting-edge technology in the educational industry for most institutions is certainly not a piece of cake as it is time-consuming and very costly." Click here to read more.

Tammi Wallace of the Greater Houston LGBT Chamber of Commerce is a panelist on The Ion's Pride in Tech event. Photo via LinkedIn

Q&A: How the Houston tech community can support LGBTQIA+ innovators

pride month

It's Pride Month, and the Houston tech community is celebrating its LGBTQIA+ community — as well as addressing some challenges faced within the business arena.

The Ion Houston, Austin-based Pride.VC, and Houston-based Sesh Coworking are collaborating on a Pride in Tech event, tomorrow, June 24, at noon at the Ion. It's free to attend and all is welcome. The Ion is also encouraging attendees to come early for a cup of coffee at Common Bond for the weekly Cup of Joey networking happy hour from 8:30 to 10:30 am.

The event will feature a panel moderated by Sesh's Maggie Segrich and Meredith Wheeler, and will tackle topics around how Houston can do more to build a truly inclusive business community. The panelists include

Wallace, who co-founded the Greater Houston LGBT Chamber of Commerce in 2016, joined InnovationMap for a quick Q&A ahead of the event.

InnovationMap: What kind of challenges do LGBTQIA+ founders in Houston face these days?

Tammi Wallace: First, LGBTQIA+ founders need to be at the table and have a voice. When we launched the Greater Houston LGBT Chamber of Commerce in 2016, our primary goal was to make sure we were seen, heard and engaged.

A seat and a voice at the table matters because LGBTQIA+ founders often lack visibility in the broader economic ecosystem and continue to experience discrimination. This means they cannot engage with their full and authentic selves as entrepreneurs and experience unique challenges. More specifically, they face challenges with access to venture capital and angel investment funds and these entrepreneurs lack strong LGBTQIA+ role models and mentors.

In fact, some LGBTQIA+ business owners never come out because they fear losing customers or clients. We hear stories all the time about LGBTQIA+ founders not seeking either traditional or non-traditional funding because they fear that they will have to out themselves in the process and fear discrimination and a lack of acceptance in the process. Disclosing personal information, such as financial information, in some cases, can effectively out them as an LGBTQIA+ person. Funding paths must be fully inclusive and ensure that the process is viewed from the lens of the LGBTQIA+ entrepreneur and how that can impact their access to capital.


    IM: How would you recommend these founders find the community and support they are looking for? 

    TW: Definitely get involved with the Houston LGBT Chamber of Commerce. Since 2016, the chamber has been working to build a strong community to support LGBTQIA+ entrepreneurs and get them access to resources to help their businesses grow and thrive.

    We create connections and give LGBTQIA+ entrepreneurs a space and place to walk through the door as their full and authentic selves. Through the Chamber, LGBTQIA+ founders can find support, whether from other entrepreneurs, mentors and Corporate Partners. We collaborate with the National LGBT Chamber of Commerce (NGLCC) as well as the other LGBTQIA+ chambers in Texas to drive connections and build a strong LGBTQIA+ business network across the country and the state.

    We encourage LGBTQIA+ businesses to get LGBTBE® Certified as well which offers even more connection with other certified businesses, major corporations and other key stakeholders and mentoring opportunities with major companies. We can help these founders get started with the LGBTBE® certification process and tap into national, regional and statewide resources.

    IM: How do you recommend startup development organizations, investors, and other businesses become better allies to the LGBTQIA+ startup community? 

    TW: Ensure that LGBTQIA+ entrepreneurs and business and community leaders are engaged with your organization. Organizations like the Greater Houston LGBT Chamber of Commerce and the Ion are working "boots on the ground" to support the LGBTQIA+ business community and can offer the opportunity for meaningful collaboration. We also recommend advocating for others -- when you are around a table, look around and if the LGBTQIA+ community is not being represented, ask why.

    If representation is around the table, be intentional to ensure that we have a voice. As organizations that are involved in Houston's economic ecosystem, be strong and visible advocates for the LGBTQIA+ business community through engagement of businesses and the Chamber throughout the year. Be engaged -- not just during Pride Month, but twelve months out of the year.

    Whether a startup, investor or a business, you can help raise the profile for LGBTQIA+ businesses and the LGBTQIA+ business movement.

    Supporting LGBT-founded startups is crucial to Houston business success. Ylanite Koppens/Pexels

    Houston business leader on the importance of engaging the LGBTQ community

    Pride Month

    When we think about different groups within the business ecosystem in our region, the LGBTQ business community historically has not been at the table. As we close this year's Pride Month, it's time to reflect on the the importance the LGBTQ population has within Houston and local businesses.

    While the LGBTQ community has realized historic gains, such as marriage equality, serious gaps in legal protections remain, resulting in discrimination in employment, housing and public accommodations. In fact, there are twenty-nine states where a person can be fired for their sexual orientation or gender identity. That kind of job insecurity coupled with an entrepreneurial spirit has driven many in the LGBTQ community to start their own businesses.

    Many LGBTQ-owned businesses in the region are obtaining the LGBTBE® certification, opening the door for these business owners to participate in corporate supplier diversity programs such as those offered by Fortune 500 corporations like Bank of America, Chevron, Shell. and United. These and many other companies greatly value diverse suppliers as part of their supply chain inclusivity goals and they embrace the diversity that LGBTQ businesses bring as part of that inclusion equation. The LGBTBE® certification is part of supplier diversity and inclusion programs that typically include participation of businesses owned by minorities, veterans, and women as examples.

    The Greater Houston LGBT Chamber of Commerce is hosting its annual Pride in Business Celebration on Friday, June 28, at 5:30 pm at the Hyatt Regency Houston. Click here for more information.

    Why get certified?

    Traditionally, LGBTQ business owners have been excluded from these opportunities within the broader business community and many have stayed in the closet because of the fear of losing clients, employees, and revenue. In fact, many LGBTQ business owners can experience a coming out process in their professional life that is entirely different from the one they have experienced in their personal life. The LGBTBE® certification gives LGBTQ owned businesses an opportunity to participate in contracting opportunities and to be valued for the service or product they provide, as well as because of who they are as LGBTQ suppliers and as part of an ecosystem of diverse entrepreneurs.

    How does a business qualify for the certification?

    A company must be at least 51 percent LGBTQ-owned, operated, managed, and controlled along with other criteria comparable to similar certification programs. The certifying body for the LGBTBE® certification is the National LGBT Chamber of Commerce (NGLCC). In order to get certified, a business owner should complete the application through the NGLCC.

    Greater Houston LGBT Chamber members are eligible for a fee waiver, as part of the Houston chamber's affiliate relationship with the NGLCC. This is a "win-win" for businesses with the waiver of the fee and the opportunity to take advantage of the many benefits and support offered to LGBTQ entrepreneurs through the Chamber.

    What's the impact?

    Making sure that the LGBTQ business community has access to economic opportunity is good for business and good our region. Looking forward to the goal of full and equal rights for the LGBTQ community, economic opportunity is a key milestone for LGBTQ entrepreneurs and the community as a whole. The LGBTQ business community is part of the economic fabric in our region and key to Houston's economic success.

    While the LGBTQ business community is poised for tremendous growth in the region as corporations and consumers seek out LGBTQ-supportive businesses, the traditional barriers for LGBTQ-owned businesses must be removed and economic opportunity a priority whether through the LGBTBE® certification or actively engaging LGBTQ entrepreneurs with the broader business community.


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    Tammi Wallace is the co-founder and board chair of the Greater Houston LGBT Chamber of Commerce. She is also the founder and principal consultant of EnFocus Group, which connects organizations to the power of LGBTQ diversity and inclusion through training and consulting.

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    Rice Alliance and the Ion leader Brad Burke to retire this summer

    lasting legacy

    Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

    Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

    “Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

    During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

    “Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

    One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

    Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

    Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

    In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

    “Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

    Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

    “The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

    Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

    Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

    cancer research

    With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

    Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

    Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

    “Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

    In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

    With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

    Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

    Houston booms as No. 2 U.S. metro for new home construction

    Construction Boom

    Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

    Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

    Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

    Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

    A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

    Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

    Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

    Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

    While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

    “Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

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