3 Houston innovators to know this week

Who's Who

From a former astronaut to growing software company leaders, here are three innovators to know. Courtesy photos

This week's set of innovators to know are familiar with pivoting careers. All three had successful careers — from energy finance to space exploration — before jumping into a new field. And each set of prior experience prepared them for what they are doing today.

Alex Colosivschi, founder and CEO of Currux

Courtesy of Currux

Alex Colosivschi had a successful career in energy finance before he started his company, Currux. He was walking in his Rice Village neighborhood when the idea came to him. He realized that despite the green surroundings, he was choked by the smell of engine exhaust.

"I started with thinking about the future of energy and how the industry will adapt to a world of electric, autonomous and shared mobility, and the need to reduce CO2 emissions," he says.

Tim Kopra, partner at Blue Bear Capital

Courtesy of Blue Bear Capital

It might not be easy to connect the dots between Tim Kopra's NASA career and his current role at Blue Bear Capital, but for Kopra, it makes perfect sense.

"On face value, it may sound like an odd match, taking someone with a tech and operational background and putting them in venture, but quite frankly it feels very familiar to me because my career has really been focused on working on complex technology and operations with very small teams," Kopra says. "It's not just a theoretical understanding of the technology, but understanding how to use the technology and how it works."

Stuart Morstead, co-founder and COO of Arundo Analytics

Courtesy of Arundo Analytics

Stuart Morstead spent the bulk of his career in consulting, so he knows the importance of understanding the needs an industry has. He co-founded Arundo Analytics to address the analytical needs energy companies have on a regular basis.

Morstead says that most industrial companies that encounter issues with operations such as equipment maintenance "lack the data science and software capabilities to drive value from insights into their daily operations."

Arundo is growing — both from a funding standpoint as well as through its staff. The Houston company has big plans for its 2019.

It might not be surprising to discover that the energy capital of the world is a hub for energy startups. Getty Images

5 emerging energy tech companies in Houston revolutionizing the industry

The Future is Now

If you thought Houston's wildcatter days were exciting, just you wait. Houston has an emerging ecosystem of tech startups across industries — from facial recognition devices used at event check in to a drone controller that mimics movement in space.

A somewhat obvious space for Houston entrepreneurs is oil and gas. While the energy industry might have a reputation of being slow to adapt new technologies, these five Houston startups are developing the future of the industry — one device at a time.

Future Sight AR

Lori-Lee Emshey's Future Sight AR is revolutionizing antiquated construction tools using augmented reality. Courtesy of Future Sight AR

Working on an oil and gas construction site is like constructing a really large puzzle — one that, if constructed incorrectly, could have dangerous and costly consequences. On her first job in the industry, Lori-Lee Emshey was required to move through the site with a pen and a clipboard to mark down any issues or problems, only to later log that information into a computer. It was a slow process, and she felt frustrated by that.

"I was really shocked at how much work they were doing with such little technology," Emshey says. "I thought, 'there's so much room for innovation here.'"

She created Future Sight AR that uses artificial reality technologies on a smart device so that technicians can instantly see instructions and solutions for the hardware they are constructing on the site. Read more about Future Sight AR here.

Nesh

Nesh's digital assistant technology wants to make industry information more easily accessible for energy professionals. Photo courtesy of Thomas Miller/Breitling Energy

Access to information is endless in the digital age, but Sidd Gupta wanted to create a digital assistant that specifically focused on the energy industry. Nesh is an information bot that users can chat questions to. Think: Siri or Alexa, but with an engineering degree.

"We created Nesh as something super-simple to use," Gupta says. "There's no learning curve, no technical knowledge required, you just need to speak plain English."

Nesh has the potential to change productivity and hiring requirements in various energy companies. Read more about Nesh here.

Cemvita Factory

The Karimi siblings have created a way to synthetically convert CO2 into glucose, and they are targeting the energy and aerospace industries for their technology. Courtesy of Cemvita Factory

Energy companies are getting more and more pressure to create a sustainable solution for the carbon dioxide refineries produce on a daily basis. Houston-based Cemvita Factory has a solution. The company has a patented technology that can convert CO2 into glucose — just like plants do in the photosynthesis process.

"We go to these companies and say, 'What do you want to convert CO2 into?,'" Moji Karimi, co-founder of Cemvita, says. "Then, we do a quick pilot in six months in our lab, and we show them the metrics. They decide if they want to scale it up."

The company also has big plans for making an impact on the aerospace industry too. Read more about Cemvita here.

NatGasHub.com

Jay Bhatty looked at how pipeline data reached traders and thought of a better way. Getty Images

Information around natural gas pipelines — such as whether a pipeline has capacity issues that could trigger a spike in prices — has, for years, been scattered across the web. Now, Houston-based NatGasHub.com aggregates pipeline data from dozens upon dozens of websites.

Jay Bhatty, a veteran of the natural-gas-trading business, founded the Houston-based NatGasHub.com platform, which runs on cloud-based software, launched in late 2017. The company is already profitable and hasn't taken any outside funding. Read more about NatGasHub.com here.

Arundo Analytics

This growing Houston company is providing industrial industries with smart analytics. Courtesy of Arundo

While information can be slow and siloed between energy companies, energy professionals come across the same problem within their own organization. Arundo Analytics is developing software to help connect the dots within an energy company's operations.

Stuart Morstead, co-founder and chief operating officer of Arundo, says that most industrial companies that encounter issues with operations such as equipment maintenance "lack the data science and software capabilities to drive value from insights into their daily operations." Read more about Arundo Analytics here.

This growing Houston company is providing industrial industries with smart analytics. Getty Images

Houston software company looks to grow its workforce internationally

Staffing up

A Houston-based analytics-focused company is gearing up for growth in 2019 and plans to staff up its headquarters and remote offices abroad.

Arundo Analytics Inc. brings industrial companies — which sometimes are slow to adopt brand-new technology — into the world of machine learning and advanced analytics to help boost revenue, cut costs and reduce risks.

The startup's enterprise software gives asset-heavy industrial businesses "a virtual window into their day-to-day operations," says Stuart Morstead, co-founder and chief operating officer of Arundo. Among the operations that benefit from software are equipment maintenance, safety, logistics and scheduling.

Morstead points out that most industrial companies that encounter issues with operations such as equipment maintenance "lack the data science and software capabilities to drive value from insights into their daily operations."

Arundo aims to solve that problem by incorporating machine learning and advanced analytics — the kind of innovations emanating from the likes of Amazon, Google, and IBM — into everyday business operations at industrial companies, says Morstead, a former partner at consulting firm McKinsey & Co. and a graduate of Rice University.

Aside from its broad enterprise software, Arundo supplies out-of-the-box applications that tackle individual industrial challenges like flow metering for the offshore oil and gas industry and monitoring the condition of equipment. The virtual cloud-based multiphase flow meter is sold as part of a software package from industrial technology giant ABB.

More than 50 of Arundo's estimated 110 employees work on that technology from the startup's headquarters in downtown Houston. To propel its growth, Arundo plans to add employees this year in Houston as well as its other offices in Canada, Norway, Sweden and the United Kingdom, according to Morstead.

In 2016, Arundo graduated from Stanford University's StartX accelerator program. A year later, Arundo was named to the MIT STEX25 accelerator program by the Massachusetts Institute of Technology Startup Exchange.

Since its founding in 2015, Arundo has raised more $35 million in capital, including a Series A round of $28 million that closed in the first half of 2018. Investors include Sundt AS, Stokke Industri, Horizon, Canica, Strømstangen, Arctic Fund Management, Stanford-StartX Fund and Northgate Partners.

Aside from drawing more funding in 2018, the startup set up several strategic partnerships designed to increase the adoption of Arundo's software in sectors such as oil and gas, manufacturing, shipping, construction and maritime. Among the new partners are Dell Technologies, DNV GL's Veracity platform and WorleyParsons.

Going forward, Morstead says Arundo aims to bring its software expertise, business prowess and "world-class data science" to even more industrial companies and their physical assets as part of the global Industrial Internet of Things sector. That market is projected to approach $1 trillion by 2025, up from $100 billion in 2016.

To be sure, Arundo is competing in a market that's rife with opportunity. Consulting firm Accenture estimates the IIoT market could add $14.2 trillion to the global economy by 2030.

"Arguably the biggest driver of productivity and growth in the next decade, the Industrial Internet of Things will accelerate the reinvention of sectors that account for almost two-thirds of world output," the Accenture report says.

Tor Jakob Ramsøy, founder and CEO of Arundo, certainly grasps the enormous potential of IIoT.

"Asset-heavy companies can no longer afford to make business decisions based on an incomplete view of their organization," Ramsøy, a former McKinsey partner, said in a 2018 news release. "By combining deep data and [artificial intelligence] knowledge with decades of cumulative experience in enterprise consulting, Arundo is ushering in a new era in IIoT."

Tracking performance

  

Courtesy of Arundo

Arundo's Condition & Performance Monitoring Software can easily be plugged into a company's system and track its equipment using cloud technology.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Rice team keeps CO2-to-fuel devices running 50 times longer in new study

Bubbling Up

In a new study published in the journal Science, a team of Rice University researchers shared findings on how acid bubbles can improve the stability of electrochemical devices that convert carbon dioxide into useful fuels and chemicals.

The team led by Rice associate professor Hoatian Wang addressed an issue in the performance and stability of CO2 reduction systems. The gas flow channels in the systems often clog due to salt buildup, reducing efficiency and causing the devices to fail prematurely after about 80 hours of operation.

“Salt precipitation blocks CO2 transport and floods the gas diffusion electrode, which leads to performance failure,” Wang said in a news release. “This typically happens within a few hundred hours, which is far from commercial viability.”

By using an acid-humidified CO2 technique, the team was able to extend the operational life of a CO2 reduction system more than 50-fold, demonstrating more than 4,500 hours of stable operation in a scaled-up reactor.

The Rice team made a simple swap with a significant impact. Instead of using water to humidify the CO2 gas input into the reactor, the team bubbled the gas through an acid solution such as hydrochloric, formic or acetic acid. This process made more soluble salt formations that did not crystallize or block the channels.

The process has major implications for an emerging green technology known as electrochemical CO2 reduction, or CO2RR, that transforms climate-warming CO2 into products like carbon monoxide, ethylene, or alcohols. The products can be further refined into fuels or feedstocks.

“Using the traditional method of water-humidified CO2 could lead to salt formation in the cathode gas flow channels,” Shaoyun Hao, postdoctoral research associate in chemical and biomolecular engineering at Rice and co-first author, explained in the news release. “We hypothesized — and confirmed — that acid vapor could dissolve the salt and convert the low solubility KHCO3 into salt with higher solubility, thus shifting the solubility balance just enough to avoid clogging without affecting catalyst performance.”

The Rice team believes the work can lead to more scalable CO2 electrolyzers, which is vital if the technology is to be deployed at industrial scales as part of carbon capture and utilization strategies. Since the approach itself is relatively simple, it could lead to a more cost-effective and efficient solution. It also worked well with multiple catalyst types, including zinc oxide, copper oxide and bismuth oxide, which are allo used to target different CO2RR products.

“Our method addresses a long-standing obstacle with a low-cost, easily implementable solution,” Ahmad Elgazzar, co-first author and graduate student in chemical and biomolecular engineering at Rice, added in the release. “It’s a step toward making carbon utilization technologies more commercially viable and more sustainable.”

A team led by Wang and in collaboration with researchers from the University of Houston also recently shared findings on salt precipitation buildup and CO2RR in a recent edition of the journal Nature Energy.

---

This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

View All Listings